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Search Results within category "Women's Health"

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Suggestions within category "Women's Health"


38 Study Matches

Site for Tomosynthesis Mammographic Imaging Screening Trial (TMIST)_EA1151_PSCI 19-080

This study is being done to answer the following question: Can tomosynthesis mammography, three-dimensional x-ray imaging of the breast, lower your chance of developing life-threatening breast cancer through routine screening compared with digital mammography, two-dimensional x-ray imaging of the breast? We are doing this study because we want to find out which of the two usual approaches to breast cancer screening are better in the early detection of life-threatening breast cancers.
Swati Shah at sshah@pennstatehealth.psu.edu
Female
18 year(s) or older
This study is also accepting healthy volunteers
NCT03233191
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Inclusion Criteria:
Women age 45 or older and under age 75 at the time of study entry
Patients must be scheduled for, or have intent to schedule, a screening mammogram.
Patients must be able to tolerate digital breast tomosynthesis and fullfield digital mammographic imaging required by protocol.
Patients must be willing and able to provide a written informed consent.
Exclusion Criteria:
Women of childbearing potential must not be known to be pregnant or lactating.
Patients must not have new symptoms or signs of benign or malignant breast disease
Patients must not have had a screening mammogram within the last 11 months prior to date of randomization.
Patients must not have previous personal history of breast cancer including ductal carcinoma in situ
Patients must not currently have breast enhancements (e.g., implants or injections).
Prevention, Cancer, Women's Health
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Location
Hershey, PA

Phase 2, Multicenter, Double-blind (Sponsor-unblinded), Randomized, Placebo-Controlled Study of the Safety and Efficacy of Elagolix in Women with Polycystic Ovary Syndrome

The objective of the study is to see if elagolix can help with the symptoms experienced by women with a diagnosis of PCOS
Barbara Scheetz at bscheetz@pennstatehealth.psu.edu or 717-531-4483
Female
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03951077
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Inclusion Criteria:
women aged 18-35
diagnosis of PCOS
Current or history of irregular periods defined as 8 or fewer periods per year
BMI between 18 and 38 kg/m2
Exclusion Criteria:
currently pregnant or less than 6 months post partum
planning a pregnancy within the next 12 months
diabetic
surgical history of tubal ligation, tubal occlusion or salpingectomy
osteoperosis or other bone disease
Women's Health
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Location
Hershey, PA

Respect and Satisfaction in Same-Sex Romantic Relationships

The purpose of this study is to expand on previous research looking at respect and relationship satisfaction among heterosexual relationships and compare it to that of same-sex relationships to find where they are similar or different. Participants will complete self-report measures regarding their romantic relationships, including respect toward partner, satisfaction, and attitudes toward love. 30 minutes will be required for the study.
Michelle Yarwood at mxg925@psu.edu or 814-867-4851
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
age 18 years or older
Exclusion Criteria:
younger than 18 years of age
Men's Health, Mental & Behavioral Health, Women's Health
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COVID-19 in Pregnancy Study

We are interested in learning more about how COVID-19 impacts the health of moms and their babies from pregnancy to the first month of life. This study will help us gather more evidence that could guide the clinical care provided to moms and their babies.
Kristin Sznajder at ksznajder@phs.psu.edu
Female
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Pregnant
>=18 years
Seeking care at Penn State Health
Exclusion Criteria:
Not planning on being a caregiver to the infant after it is delivered
Children's Health, Pregnancy & Infertility, Women's Health
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Site For ENDOmarker

Site For ENDOmarker
Patsy Rawa at prawa@pennstatehealth.psu.edu or 717-531-3692
Female
18 year(s) or older
This study is also accepting healthy volunteers
NCT03161704
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Inclusion Criteria:
Scheduled to undergo gynecologic surgery
Exclusion Criteria:
Currently pregnant
Current or past diagnosis of any malignancy (exception melanoma skin cancer)
Known to be HIV-positive
Clinical evidence of active cervical infection
Clinical evidence of pelvic inflammatory disease (PID)
Women's Health
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Hershey, PA

A randomized double-blind placebo controlled trial to assess the effectiveness of low-dose naltrexone in combination with standard treatment in women with chronic pelvic pain secondary to endometriosis.

Pelvic pain associated with endometriosis is in part due to inflammation of a layer of tissue in the abdomen (stomach area). This leads to the great potential of relieving endometriosis related pelvic pain in a non-narcotic medication by decreasing the inflammation. The purpose of this study is to evaluate how a low dose of naltrexone compared to placebo (inactive substance) impacts your daily pain and the quality of your life with endometriosis. Naltrexone is approved by the U.S. Food and Drug Adminstration (FDA) for the treatment of opioid overdose and addiction. At much lower doses, naltrexone has been shown to be beneficial in pain relief of inflammatory disorders with promising results, but the use of the low dose in this study to treat endometriosis pain is investigational and has not been approved by the FDA.
Heidi Watts at hwatts@pennstatehealth.psu.edu or 717-531-6272
Female
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03970330
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Inclusion Criteria:
Surgical diagnosis of endometriosis
Pelvic Pain associated with endometriosis
age 18-45
Exclusion Criteria:
Daily opioid use
Pregnant
Breast Feeding
Allergy to oxycodone, motrin, naltrexone
Pain Management, Women's Health
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Location
Hershey, PA

Assessment of Endothelial Function in Post-Menopausal Women with Depression

The goal of this project is to understand the contribution of depression on blood vessel function in post-menopausal women, a population at heightened risk for cardiovascular disease. Currently, little is known about the combined impact of depressive symptoms and the effects of reproductive aging on blood vessel function. As such, there is a greater need to characterize blood vessel function in post-menopausal women with depressive symptoms. Participants depressive symptoms will be assessed and non-invasive vascular measures will be performed.
Jigar Gosalia at jzg691@psu.edu or 814-863-3182
Female
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Post-menopausal women who are at least 1 year removed from their final menstrual period and between the ages of 50 and 80
Individuals with moderate to severe depression as reflected by Patient Health Questionnaire (PHQ-9) score of 10 or greater for the depressed post-menopausal women group
We also need non-depressed healthy post-menopausal women are needed as well for control group comparisons
Free from blood-pressure lowering medication and lipid lowering medication
Exclusion Criteria:
Individuals with any overt cardiovascular, metabolic, hematologic, pulmonary, renal, musculoskeletal, and/or neurological disease(s).
Users of any tobacco and/or nicotine products (smokers, chewing tobacco, nicotine-containing patches/gum, smokeless cigarettes)
Individuals taking hormone therapy
Individuals with a BMI > 35
Heart & Vascular, Mental & Behavioral Health, Women's Health
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Study Locations

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Location
State College, PA

Barriers to Transgender Healthcare in Rural Communities

The purpose of this study is to comprehensively explore the barriers to healthcare among rural transgender or non-binary adults in rural Pennsylvania, using a convergent mixed-methods approach.
Oluwamuyiwa Adebayo at owa2@psu.edu or 814-867-4656
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Aged 18 years and older
Identify as transgender or non-binary or genderqueer
Fluent in English
Reside in Rural Pennsylvania County
Exclusion Criteria:
Younger than 18 years
Identify as cisgender
Men's Health, Prevention, Women's Health
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