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Suggestions within category "Neurology"


4 Study Matches

A data and biorepository for individuals with subjective cognitive decline (SCD), mild cognitive impairment (MCI), dementia, and other individuals at increased risk for dementia

This research is being done to help us better understand the risk factors and protective factors for cognitive decline in people who are at increased risk for dementia. The goal of the study is to establish a data and biorepository for people at increased risk for dementia.
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Age 18 and older
Patient participants
•Meet the criteria for subjective cognitive decline, mild cognitive impairment, dementia or at risk for any
Health controls
•Normal age and education-adjusted performance on the Montreal Cognitive Assessment Test or another standardized cognitive screening test
Exclusion Criteria:
Age less than 18
Neurology
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Study Locations

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Location
Hershey, PA

Family Caregiver’s Perspectives on the Dyadic Experiences of Delirium Superimposed on Dementia.

The purpose of this study is to understand family caregiver’s views and experience related to caring for older adult with acute/sudden confusion on top of dementia.
Priyanka Shrestha at pxs409@psu.edu or 410-841-9408
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Family caregiver of Age 18 years or older
Family caregiver of an older adult with diagnosed dementia
Family caregiver living together or in regular contact with the older adult
Family caregiver who takes care of an older adult hospitalized in the past year
Family caregiver who takes care of an older adult who experienced sudden or worsening confusion
Exclusion Criteria:
Age <18 years
Non-english speaking
Not living in United States
Education, Neurology, Mental & Behavioral Health
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Site for Therapy in Amyotrophic Lateral Sclerosis (TAME)

This is a phase IIB multi-centered, double blind, placebo controlled study to assess the safety and efficacy of a medication called memantine in people with ALS. This study is designed to validate the preliminary data that suggests memantine can slow down the course of ALS and also to determine if memantine can improve ALS patients who have characteristics of frontotemporal dementia.
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT02118727
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Inclusion Criteria:
Age 18-85
Diagnosed with amyotrophic lateral sclerosis (ALS)
ALS Functional Rating Scale (ALSFRS-R) score > 25
Has a caregiver willing to help with study activities
Exclusion Criteria:
Forced vital capacity (FVC) ≤ 60% predicted
ALS-related weakness for more than 3 years
History of liver disease
Kidney failure
Neurology
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Study Locations

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Location
Hershey, PA

Prion Disease Registry at Penn State Health

This research is being done to help us better understand prion disease. The goal of the study is to establish a registry of patients with rapidly progressive dementia, suspected prion disease, or confirmed prion disease. A disease registry is an extensive collection of data related to patients with a specific diagnosis that plays an important role in the surveillance of a disease. Prion disease has poor prognosis, yet there is currently no approved treatment. The collection of information from prion patients will help us gather information to help advance the study of this pathology and potentially help contribute to treatments and preventative methods in the future.
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
Aged 18 or older
Diagnosed with prion disease
Suspected prion disease
Rapidly progressive dementia
Exclusion Criteria:
Aged less than 18
Without diagnosis of or suspected prion disease, or without rapidly progressive dementia
Neurology
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