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Search Results within category "Women's Health"

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Suggestions within category "Women's Health"


4 Study Matches

Management Of Pain After Cesarean Trial

This is a double blinded, placebo-controlled randomized controlled trial to test the efficacy of a combination of acetaminophen and ibuprofen administered to patients on schedule compared to ibuprofen and placebo on the patient's reported pain score on the second post-operative day after Cesarean delivery. We will also record opiate consumption and pain scores throughout the hospitalization of participants, and will survey patients at one and two weeks after surgery regarding opiate consumption and quality of life.
Female
All
This study is also accepting healthy volunteers
NCT03929640
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Inclusion Criteria:
Pregnant woman
Planned delivery via C-section
Pfannenstiel ("bikini line") skin incision
Able to read and speak English fluently
Exclusion Criteria:
Major intra-operative or post-operative complication such that clinical recommends patient should not receive non-steroidal anti-inflammatory drugs
Unplanned surgery (hysterectomy, bowel/bladder repair, cystoscopy)
Allergy or contraindication to study medication
History of opioid or other substance use disorder either before or during pregnancy
History of kidney or liver disease
Pregnancy & Infertility, Women's Health
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Study Locations

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Location
Hershey, PA

COVID-19 in Pregnancy Study

We are interested in learning more about how COVID-19 impacts the health of moms and their babies from pregnancy to the first month of life. This study will help us gather more evidence that could guide the clinical care provided to moms and their babies.
Kristin Sznajder at ksznajder@phs.psu.edu
Female
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Pregnant
>=18 years
Seeking care at Penn State Health
Exclusion Criteria:
Not planning on being a caregiver to the infant after it is delivered
Children's Health, Pregnancy & Infertility, Women's Health
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Role of microRNA activation of lectin-like oxidized LDL receptor (LOX-1) mechanisms in microvascular dysfunction in women with endometriosis

Endometriosis is a gynecological disorder associated with chronic pelvic pain, pain during intercourse, and infertility. With endometriosis, endometrium-like tissue is found in sites outside the uterine cavity. This disorder affects 6% - 10% of women of reproductive age. It can be as high as 35-50% in women who have pain or infertility. Endometriosis is associated with higher risk of hypercholesterolemia and hypertension that increases risk for cardiovascular disease (CVD). CVD is characterized by dysfunction of the blood vessels of the body. CVD is the leading cause of death in women. Two groups of women complete this study: 1) healthy women between the ages of 18 and 45 years (Controls); 2) women between the ages of 18 and 45 years with endometriosis. The screening and two experiments include blood draws. After passing a medical screening, each subject participates in a microdialysis (MD) experiment before and after 6-9 days of oral atorvastatin therapy (10mg/day). Atorvastatin (brand name: Lipitor) is an FDA-approved drug that physicians prescribe to lower blood cholesterol. The atorvastatin also suppresses substances made by the body that increase the risk of CVD. MD is a procedure in which a thin tube of membrane that mimics a capillary blood vessel is implanted in the skin. Substances of interest are added to the saline flowing through the MD sites and are delivered into small areas of skin. The MD experiments combine the perfusion of the test-substances with local heating of the skin to explore the causes for the dysfunction of blood vessels and increased risk for CVD that occurs with endometriosis.
Susan Slimak at sks31@psu.edu or 814-863-8556
Female
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Women, Ages 18-45
Do or do not have endometriosis
Have normal blood pressure
Exclusion Criteria:
Use of nicotine-containing products (e.g. smoking, chewing tobacco, etc.)
High Blood Pressure
Abnormal liver function
Known allergy statins (Lipitor)
Pregnant or Breastfeeding
Heart & Vascular, Pregnancy & Infertility, Women's Health
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Location
State College, PA

Coparenting, Infant Sleep, and Infant Development: An Intervention Study

This application proposes a randomized clinical trial (RCT) to evaluate the effects of a sleep-enhanced adaptation of an evidence-based transition-to-parenting coparenting intervention program [Family Foundations - FF). The study has three arms. In one arm, families will experience FF as originally formulated; in the second, families will receive an adapted FF that emphasizes coparenting in infant sleep contexts; the third arm will serve as controls. Assessments of coparenting and parenting in infant sleep contexts, parental adjustment to infant sleep behavior, choices about sleep arrangements, infant and parent sleep quality, and infant socio-emotional functioning, will serve as outcomes.
Morgan Loeffler at FF@psu.edu or 717-695-7050
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT03187561
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Inclusion Criteria:
Parents must live together
Parents must be expecting their first baby together
We must start working with the couple before the baby is born
Parents must be 18 years or older
Families who can speak and understand English
Exclusion Criteria:
Single-parent families
Families with more than one-child
Familes who cannot speak or understand English
Families in which one parent is under the age of 18
Pregnancy & Infertility, Sleep Management, Women's Health
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Study Locations

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Location
Carlisle, PA
Harrisburg, PA
Hershey, PA