Refine your search

Search Results within category "Addiction & Substance Abuse"

Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.

Search all categories
11 Study Matches

Non-invasive sampling method of respiratory exhaled breath condensate (EBC) and nasal mucosa for smoking related biomarkers

The objective of this preliminary study is to collect EBC samples from 20 healthy volunteers for use in the measurement of specific tobacco related biomarkers of exposure and oxidative stress. Laboratory studies will also be conducted to detect specific markers and to determine their variability and stability and establish optimal collection and processing protocols
Reema Goel at rgoel@phs.psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Able to understand and provide consent
Exclusion Criteria:
1. Unstable or significant medical conditions that affect oxidative stress
Addiction & Substance Abuse, Prevention
  Email this study information to me
  Contact the study team
  Show all 1 locations

Study Locations

Hide all locations
Location
Hershey, PA

Randomized trial of low nicotine cigarettes plus electronic cigarettes in smokers

This study will examine the health effects of lowering the nicotine content in cigarettes while having access to an electronic cigarette.
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT04058717
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Ages 21-70
Smoke 5 or more cigarettes per day
Must be willing to both switch to a different type of cigarette and try an electronic cigarette
No serious quit attempt or use of smoking cessation medication in the past 30 days
Meet diagnostic criteria for current or lifetime mental health condition
Exclusion Criteria:
Women who are pregnant, nursing, or trying to become pregnant
Any known allergy to propylene glycol or vegetable glycerin
History of difficulty providing blood samples
Other member of the household currently participating in the study
Unstable or significant medical condition in the past 3 months
Addiction & Substance Abuse, Lung Disease & Asthma, Mental & Behavioral Health
  Email this study information to me
  Contact the study team
  See more information
  Show all 1 locations

Study Locations

Hide all locations
Location
Hershey, PA

The Effect of Resistance Exercise on Craving and Cannabis Use in Individuals with Cannabis Use Disorder

Cannabis is the most widely used illicit drug and rates of hazardous use, and cannabis use disorders (CUDs), have continued to rise in recent years. Increased exposure produces higher risk for detrimental psychological and behavioral effects of cannabis use. Given this increased prevalence of problematic cannabis use, identifying effective behavioral strategies for individuals experiencing problems with addiction would offer significant benefits. Exercise, particularly resistance exercise, is a behavioral intervention with considerable potential as an adjunctive treatment for CUD. No prior study has investigated the effects of an acute bout of resistance exercise on cannabis craving and consumption, nor has prior research identified what psychobiological mechanisms may underlie these exercise potentiated effects. The aims of this proposal seek to address these issues by implementing an acute resistance exercise protocol in men and women who have severe cannabis use disorder. This proposal will examine the acute effects of resistance exercise on craving, mood, anxiety, and markers of reward and stress regulation. In addition, this proposal will examine the trajectory of these effects in the subsequent days.
Gwendolyn Thomas at gat112@psu.edu or 814-863-3172
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Cannabis Use
Between 18-30 years old
Recreationally trained
Able to read write English and complete study evaluations
Provide negative toxicology screenings for nicotine or alcohol at intake
Exclusion Criteria:
Women who are pregnant or lactating
Known endocrine disorder
Blood clotting disorders
Any psychiatric disorder or current psychiatric symptoms
Inability to give informed consent
Addiction & Substance Abuse
  Email this study information to me
  Contact the study team
  Show all 1 locations

Study Locations

Hide all locations
Location
State College, PA

Establishing the effect of flavor on the addictive potential of electronic cigarettes

For the current study, smokers will use an electronic cigarette in addition to their usual cigarettes for 4 weeks. The electronic cigarette will contain sweet or tobacco flavored liquid that may or may not contain nicotine. Participants will complete functional magnetic resonance imaging scans at the beginning and end of the study to measure how the brain responds to the electronic cigarette flavor.
Kenneth Houser at abl@pennstatehealth.psu.edu or 717-531-5473
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT03905928
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
21-60 years old
Smoke at least 5 cigarettes per day
Smoke regular tobacco flavored cigarettes
Not currently interested in quitting smoking
Exclusion Criteria:
Unstable or significant medical conditions
Pregnant or nursing
Regular use of flavored tobacco products
Regular use of electronic cigarettes
Implanted metal in the body
Addiction & Substance Abuse
  Email this study information to me
  Contact the study team
  See more information
  Show all 1 locations

Study Locations

Hide all locations
Location
Hershey, PA

Examining responses to rewards in the laboratory and during daily life in individuals who smoke cigarettes

The goal of this study is to learn more about how people who smoke cigarettes respond to rewards, such as winning money, under different conditions. The study uses a method called functional magnetic resonance imaging, or fMRI, which is a research method for measuring activity in the brain. In this study, we are using fMRI to measure how brain activity changes in people who smoke when they receive rewards. The fMRI measures are collected during two separate visits. Participants are also asked to fill out questionnaires and complete computer tasks while in the lab. In total, participants are required to visit the research lab on the University Park campus a total of five times. In addition, the study involves measuring thoughts and behaviors in people who smoke in real life by asking them to fill out surveys on a smartphone. Participants are asked to carry a smartphone for a total of 10 days and answer several surveys throughout each day. In order to be eligible for the study, individuals must be between 18 and 55 years old and you must smoke on a daily basis.
Julian Peck at jnp5021@psu.edu or 814-867-2333
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
18-55 years of age
Right Handed
Smokes cigarettes
Exclusion Criteria:
under 18 years of age or over 55 years of age
Left Handed
non-smokers
Men's Health, Addiction & Substance Abuse, Women's Health
  Email this study information to me
  Contact the study team
  Show all 2 locations

Study Locations

Hide all locations
Location
Altoona, PA
State College, PA

Measuring Neuroadaptations in Response to Very Low Nicotine Content Cigarettes

For this study, 75 smokers will be randomly assigned to smoke research cigarettes with a very low or normal nicotine content. Participants will complete functional magnetic resonance imaging (MRI) scans at 3 in-person study visits to help us better understand how reducing nicotine intake affects decision making and reward processing.
Brianna Hoglen at abl@pennstatehealth.psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT03612960
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Smoke greater than or equal to 5 cigarettes per day
21-60 years old
>1 year daily smoking
Live local for next 3 months
No plans to quit smoking in next 6 mos.
Exclusion Criteria:
Regular use of non-cigarette tobacco products
MRI safety contraindications
Unstable or significant medical conditions
smell dysfunction
colorblindness
Addiction & Substance Abuse
  Email this study information to me
  Contact the study team
  See more information
  Show all 1 locations

Study Locations

Hide all locations
Location
Hershey, PA

Daily Experiences and Health Behaviors

This study will investigate the relationship between daily experiences, including different types of stress, and health behavior choices among undergraduate students at the daily level.
Cara Rice at cara.rice@psu.edu or 814-863-9724
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
18 or older
25 or younger
Undergraduate at one of following PSU campuses (Abington, Altoona, Behrend, Berks, Harrisburg, Mont Alto, University Park)
Exclusion Criteria:
Under age 18
Over age 25
Not an undergraduate at one of qualifying PSU campuses
Addiction & Substance Abuse, Mental & Behavioral Health
  Email this study information to me
  Contact the study team

Habit Learning in Adolescents and Young Adults

This research seeks to exam behavioral and neural differences in the formation and maintenance of habit behavior in adolescents and adults.
Daniel Petrie at djp67@psu.edu or 814-863-5124
All
All
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Healthy adolescents between the ages of 13 to 17
Health adults between the ages of 25 to 40
Not currently taking medications known to influence body weight, task, food intake, behavior, or blood flow
Exclusion Criteria:
Outside of age ranges specified
Left handed
Diagnosed neurological or psychological condition including anxiety or depression
Currently or planning to follow a diet for weight loss
Non-removable body piercings, pacemaker, or other metal implants that would preclude safe completion of an MRI
Addiction & Substance Abuse, Food & Nutrition, Mental & Behavioral Health
  Email this study information to me
  Contact the study team
  Show all 1 locations

Study Locations

Hide all locations
Location
State College, PA

Alcohol habits in daily life

This study examines alcohol-related triggers, behaviors, and habits for 5 consecutive days in the daily lives of young adults using mobile phone surveys and alcohol monitoring wearable devices.
Rachel Bomysoad at RNB82@psu.edu or 814-863-0190
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
age 21+
Exclusion Criteria:
under age 21
Addiction & Substance Abuse
  Email this study information to me
  Contact the study team
  Show all 1 locations

Study Locations

Hide all locations
Location
State College, PA

Recruitment for Nicotine and Tobacco Related Research at Penn State Hershey

The purpose of this project is to screen potential participants for multiple research studies being conducted by tobacco researchers at Penn State Hershey. Since there are multiple IRB approved studies enrolling at Penn State Hershey with similar but not identical inclusion/exclusion criteria, it is more efficient for the researchers and participants to have one phone number to call initially for basic screening. After completing this, the participant can be redirected for more specific screening if they are found to be potentially eligible for one of the studies.
Candace Bordner at cbordner@phs.psu.edu or 844-207-4594
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Age 21 or older
Current tobacco user
Exclusion Criteria:
Age less than 21
Addiction & Substance Abuse, Lung Disease & Asthma
  Email this study information to me
  Contact the study team
  Show all 3 locations

Study Locations

Hide all locations
Location
Harrisburg, PA
Hershey, PA
York, PA

Understanding the Experiences of College Students of Color with Psychiatric Disabilities

The purpose of this study is to develop a better understanding of the lived experiences of college students of color with psychiatric disabilities, particularly related to the formation of racial identity, disability identity, and the impact of perceived discrimination.
Amber O'Shea at amo5208@psu.edu or 814-867-5721
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Currently enrolled as a college student
18 years of age or older
Capable of providing informed consent
Diagnosis of a psychiatric disability
Identify as a person of color
Exclusion Criteria:
Adults unable to provide legal consent
Individuals who are not yet legal adults
Prisoners
Unable to speak/read English Language at time of interview
Addiction & Substance Abuse, Education, Mental & Behavioral Health
  Email this study information to me
  Contact the study team
  Show all 1 locations

Study Locations

Hide all locations
Location
State College, PA