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This study seeks to examine parenting skills in responses to child misbehavior. Parents complete rating scales about their child's symptoms and behaviors and also participate in computer tasks to measure brain wave activity through EEG. There is an optional section where parent and child will be video recorded while completing activities together. Following the testing sessions are 8 weeks of counseling sessions for parents to help better manage their child's attention and behavior symptoms.

Participants will complete C-DISC while caregiver will complete rating scales around ADHD, ODD, and CD symptoms during initial visit. On the second visit, participants will complete emotion regulation tasks while EEG data is collected. Caregivers will also complete a monetary task while connected to EEG equipment. Parents will use LifeData to report inattentiveness, hyperactivity, and oppositional behaviors over 14 days. Optional parent child interaction and 8-week parenting intervention are offered to participating families.

$50

The purpose of this study is to learn more about the use of an investigational drug for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in preschool-aged (4-5 years old) children.

If after Visit 1 (Screening) your child is found to be eligible to take the study drug, he/she will need to come to the study center for 7 additional visits (Visits# 2-8; 6 weeks) and you will receive a follow-up phone call one week after your child’s last study visit (or after your child takes the last capsule of study drug). Most visits will be scheduled 1 week apart. Every participant will take 1 capsule each day for 6 weeks. Your child will either take one SPN-812 capsule every day for 6 weeks or a Placebo capsule every day for 6 weeks.

$650

In this study, we hope to better understand the neural mechanisms underlying risk for Borderline Personality Disorder (BPD) in adolescent girls. BPD is a condition that is usually found in adults. However, it may be possible to identify risk for the disorder before adulthood. Understanding who is at risk for BPD early in development is important in order to develop preventative interventions.

There will be a total of three visits - one main visit and two follow-ups. Participants will be completing questionnaires, participating in a parent-child observation task, and children will be doing an EEG assessment during the first visit. Participants will be asked to complete questionnaires and participate in a parent-child observation task during the follow-up visits.

$100

This study will examine whether patients who have insomnia with different sleep characteristics demonstrate a differential response to two common insomnia treatments, Cognitive Behavioral Therapy for Insomnia (CBT-I) and trazodone. All participants will complete a trial of CBT-I, followed by a medication trial in some participants. Participants will be evaluated with structured interviews; self-report questionnaires; in lab sleep recording; activity monitoring; saliva, blood, & urine collection for routine clinical measures; blood pressure monitoring and an EKG. All outcomes will be assessed again following the end of treatment.

Study involvement is 9-12 months Phone Screen to determine basic eligibility. There are 4-5 in person visits (first is consent/screening visit) 2-3 of the in person visits are overnight visits to the sleep lab Up to 18 other visits for treatment may be done in person or by video conference. Data is collected at home for 3-4 weeks during the 12 month period (activity monitor & blood pressure) Online self-completed surveys & structured interviews are required. A single blood sample and saliva samples will be collected Pregnancy Test, 12-Lead EKG, Medication may need to be taken in addition to the CBT-I Sessions

600.00

In this study, we hope to better understand the neural mechanisms underlying risk for personality disorders in adolescent youth. Understanding who is at risk for personality disorders early in development is important in order to develop preventative interventions.

Youth participants and their parent will be required to attend one in-person visit at our lab in Hershey, PA where youth participants will complete two computer tasks while EEG and cardiac data are collected. Youth participants will also complete questionnaires and a peer-interaction task with another peer their age. Parents will complete questionnaires and an interaction task with their child. Youth participants will complete remote surveys via a survey app for two weeks after the visit. This study includes 4 follow-up appointments (once every 6 months) which can be completed in-person or remotely via a Microsoft Teams meeting. These follow-up appointments will consist of a parent-child interaction task and surveys for parent and youth participants.

Up to $305

Children with attention and behavior problems often need external rewards to motivate them to perform challenging tasks, but we don’t yet know much about how children weigh potential rewards and the effort required to obtain the rewards. This research is being done to find out how children with varying levels of ADHD symptoms value rewards and costs when making decisions about whether or not to perform a difficult task.

There will be one in-person visit. Children will complete two computerized cognitive tasks (thinking games), and will be able to earn prizes from the points they earn on these tasks. Parents will also be asked to complete a few questionnaires that should take about 25 minutes to finish. Children can earn up to $50 in compensation for completing the study.

$50

This is a drug study for children between 7-12 years old with ADHD that will examine how central nervous system (CNS) stimulants improve anger and irritability in children. It uses only meds that are already FDA approved for ADHD. After intake, families will meet with study doctors to determine an ideal stimulant dose (no placebos in this phase) over 6 visits spaced 1-2 weeks apart. All youth showing improved ADHD and stable or reduced levels of irritability/aggression will advance to a 2 week blinded crossover trial. Participants will complete computer tasks while hooked up to EEG to measure how CNS stimulants impact processing of reward and loss. Participants will complete two EEG visits one week apart - one visit will occur while the child is on the optimal active dose of CNS stimulant from the prior phase, and the other will occur while the child is on a placebo pill. Parents will complete 3 cell phone surveys per day of their child's behavior over these 14 days. This study is expected to take an average of 10 visits over 3 months.

Parent and child will first complete an intake up two hours (30 minutes for child) to verify that child has ADHD and issues with temper problems at home. Then over 6 visits spaced 1-2 weeks apart study doctors will find the best dose of ADHD medication for the child that also helps their anger, with parents filling out weekly ratings of child behavior. All medicines used in the study are already approved to treat ADHD in children and commercially available. At least half of these visits need to occur at the study site at 22 NE Drive in Hershey, PA. For the last two weeks, there will be one in office visit per week at the Hershey office. Children will complete 3 computer games while undergoing EEG testing to measure their brain wave activity. For each of these 14 days, parents will fill out 3 cell phone surveys per day about their child’s behavior. During one of these two weeks, children will take the dose of ADHD medication that worked the best for them. For the other week, it will be replaced with placebo (fake pill). Neither parent or child will know which week is real and which week is fake medication. The total study takes between 10 to 12 visits over an average of 3 months.

child is $100 parent is $105

The purpose of this study is to examine cognitive function during perimenopause and explore how these changes may be related to sex hormone levels and other psychological effects. The present study aims to address this gap by examining associations between estrogen and progesterone, as well as fluctuations in these hormone levels, in relation to cognition, measured comprehensively across self-report, behavioral measures, and neural assessments. By examining hormonal effects on cognition, the proposed study aims to inform strategies for early detection of cognitive vulnerability, promote resilience, and ultimately improve cognitive health outcomes for women across the lifespan.

Participants will be required to attend two in-person visits at our lab in Hershey, PA. At the first in-person visit, participants will complete three behavioral tasks and two computer tasks while EEG data is recorded. Participants will also complete questionnaires and give a saliva sample. Additionally, for four-weeks after this visit, participants will complete remote cognitive games and surveys via a link sent through text message and will collect saliva samples at home three times a week during this time. After four-weeks, participants will return for their second in-person visit where they will repeat the three behavioral tasks, a few questionnaires, and give another saliva sample.

$200

This is a study that will examine the effectiveness of using Art Therapy techniques for improvement and maintenance of self-reported coping skills and symptoms co-occurring with Autism.

The study will last approximately 18 weeks. Participants will be randomly assigned to one of three groups. The assessment only group participants will spend approximately 30 minutes completing online assessments weekly. Participants assigned to the psychoeducational group will meet weekly in person for approximately 45 minutes. Participants assigned to the full art therapy intervention group will meet weekly in person for approximately 1.5 hours. Participants will be asked to complete follow-up assessments at 1 and 3-months after the last week of the assigned group.

The overarching goal of this research is to adapt, optimize, and pilot a transdiagnostic sleep and circadian intervention so that its contents and delivery are effective and sustainable for autistic adolescents

Participants will complete assessments at two time points and engage in a 6 week behavioral sleep intervention with a trained clinician.

$75.00

Sleep and circadian problems are associated with deleterious social, emotional, and cognitive outcomes, yet are modifiable. This prospective study will adapt, optimize, and test an empirically supported behavioral intervention that addresses common sleep and circadian problems of autistic adults, who are at increased risk for mental health disorders, using a transdiagnostic approach. The knowledge gained from this study will address a critical need for accessible transdiagnostic sleep interventions for autistic adults, who experience a broad range of sleep and circadian problems at high rates and often lack access to specialty care treatment.

You will need to complete self-report assessments at baseline and post-treatment, as well as collect data at home for 2 weeks by wearing a physical activity monitor on your wrist, and completing sleep diaries (short questionnaires) each day. You will also need to complete 6 weekly 50 minute sessions delivered individually by trained clinicians. You will also complete a 30-minute semi-structured interview at post-treatment with the study coordinator.

$75.00