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Study Matches
Site for Tomosynthesis Mammographic Imaging Screening Trial (TMIST)_EA1151_PSCI 19-080
This study is being done to answer the following question:
Can tomosynthesis mammography, three-dimensional x-ray imaging of the breast, lower your chance of developing life-threatening breast cancer through routine screening compared with digital mammography, two-dimensional x-ray imaging of the breast?
We are doing this study because we want to find out which of the two usual approaches to breast cancer screening are better in the early detection of life-threatening breast cancers.
Women age 45 or older and under age 75 at the time of study entry Patients must be scheduled for, or have intent to schedule, a screening mammogram. Patients must be able to tolerate digital breast tomosynthesis and fullfield digital mammographic imaging required by protocol. Patients must be willing and able to provide a written informed consent.
Exclusion Criteria:
Women of childbearing potential must not be known to be pregnant or lactating. Patients must not have new symptoms or signs of benign or malignant breast disease Patients must not have had a screening mammogram within the last 11 months prior to date of randomization. Patients must not have previous personal history of breast cancer including ductal carcinoma in situ Patients must not currently have breast enhancements (e.g., implants or injections).