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Measuring the impact of three types of resistant starch on fecal butyrate levels and the gut microbiome in healthy and obese individuals

This is dietary intervention trial that will examine the impact of consuming three different types of resistant starch on the gut microbiome and butyrate levels in normal weight and obese individuals. Participants will consume starch samples daily for 24 weeks, collecting weekly fecal samples that will be returned to the lab. Researchers will analyze the bacterial fermentation products in these samples, particularly butyrate and analyze the microbiome composition. This will allow identification of differences in resistant starch (a dietary fiber) processing between normal weight and obese individuals and will also determine if the three resistant starches tested have differing impacts on the microbiome and butyrate levels.
Darrell Cockburn at dwc30@psu.edu
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18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
BMI greater than 30
Exclusion Criteria:
Diagnosis of Inflammatory Bowel Disease
Diagnosis of Diabetes
Pregnant
Taking antibiotics
Food & Nutrition
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Location
State College, PA