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Experimental determination of the neurogenic contribution to skin flowmotion

The purpose of this study is to use spectral analysis to measure blow flow changes in superficial vessels of the arm. This study will explore how skin blood flow changes in response to heat and nerve inhibition. We will be locally heating the skin and blocking nerves of the skin with a topical numbing cream and measuring the resulting skin blood flow. Skin blood flow is measured by a machine that shines a harmless laser light onto the skin. The machine produces a signal that looks like a wave moving up and down. There is a known, and previously used, algorithm that can identify the neurogenic input-wave from the total skin blood flow-wave.
Zachary Lichter at or 814-863-8557
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Men and women aged 18-85
English speaking individuals
Exclusion Criteria:
individuals diagnosed cardiovascular, metabolic, or dermatological conditions
nicotine use (e.g. smoking, chewing tobacco, etc)
pregnancy or breastfeeding
illicit or recreational drug use
allergies to lidocaine or prilocaine
Heart & Vascular, Neurology
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State College, PA