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The role of probiotics in attenuating inflammation and improving gut health in obese adults

We are conducting a clinical study that is investigating the effects of yogurt on markers of inflammation and gut health in older adults (55-75 years old) with an elevated BMI. The participants will be given yogurt for 4 weeks and yogurt with added probiotics for 4 weeks. The order of the yogurt treatments will be random, meaning some participants will get plain yogurt first, and others will get yogurt with probiotics first. The participants will be asked to consume one 8-ounce serving of the given yogurt each day during the four weeks. At the beginning and end of each four-week period, the participants will have clinical evaluations so we can determine the impact of the yogurt on markers of inflammation and gut health. The compensation for this study is $300.
Hannah VanEvery at hqv5028@psu.edu or 814-863-3919
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18 year(s) or older
This study is also accepting healthy volunteers
NCT03418857
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Inclusion Criteria:
Overweight/obese
age 55-75
Non-smoking
Not currently taking cholesterol- or glucose- lowering medication
Not currently taking anti-hypertensive medication
Exclusion Criteria:
Smoking and/or use of other tobacco products
Fasting glucose > 126 mg/dL
Diastolic blood pressure > 100 mm Hg
Systolic blood pressure: ≥160 mm Hg
Clinical diagnosis of Inflammatory Bowel Disease (IBD) e.g. Crohn’s Disease or ulcerative colitis
Food & Nutrition
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Location
State College, PA