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Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.

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PA CURE Phase 1: Biomarkers of Traumatic Brain Injury (TBI)

The study seeks to identify the characteristics of brain function after traumatic brain injury (TBI). The data obtained through this study aims to help physicians better understand the characteristics of specific products released into the blood and cerebrospinal fluid (CSF) following a TBI, called biomarkers. In addition, we will store blood and CSF samples for later testing as new information becomes available. The long-term goal of this study is to provide physicians with the tools they need to diagnose brain injuries. This information may help doctors judge how severe a head injury is, if treatment needs to be adjusted, and it may help predict how well a patient recovers from the injury.
18 year(s) or older
This study is NOT accepting healthy volunteers
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Inclusion Criteria:
Traumatic brain injury within the preceding 48 hours
Current age 18-80 years
Head CT with acute intracranial pathology
Ability to undergo MR and PET imaging
Exclusion Criteria:
Penetrating TBI due to gunshot wound, shrapnel, or other metallic substance that would preclude patient from undergoing MR imaging
Pre-existing neurologic or neurodegenerative disorder or history of psychiatric conditions, such as major depressive disorder or psychosis
Active drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with neuropsychological testing
Contra-indication to MR imaging, such as ferrous metal, pacemakers, body weight above 125 kg, or concerns about claustrophobia
Non-native English speakers (translations are not available/validated for most neuropsychological test measures).
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Hershey, PA