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1 Study Matches

Investigation of pulse starch impact on the gut microbiome

We are investigating how the starch from pulse crops (chickpeas, lentils and dry peas) affects the gut microbiome, particularly with regards to the production of butyrate, a microbial metabolite with a number of known health benefits. We are recruiting people from two groups, those that consume a lot of these pulses and those who rarely consume them. These participants will then track their food intake for 48 hours before collecting a fecal sample which they will return to the lab. We will then use these fecal samples to conduct laboratory fermentations with pulse starches processed in a number of different ways to see what factors are important for determining the amount of butyrate that is produced. This will serve as pilot data for designing future human clinical trials.

Darrell Cockburn
Darrell Cockburn - at or 814-863-2950

18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
18-65 years of age
Either consume pulses twice or more per week or consume them once a month or less. Pulses are dry legumes such as chickpeas(Garbanzo beans), lentils or other dry peas and beans

Exclusion Criteria:
Currently or in the past month taking antibiotics
Taking a fiber supplement
Bowel problems such as IBD, IBS, chronic diarrhea or constipation
Food & Nutrition
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State College, PA ,