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Effect of Blood Flow Restriction Therapy on Knee Flexor Strength in Healthy Young Adults

This study is seeking to enroll participants who are between the ages of 18-35 that are healthy, physically active. Eligible participants will complete laboratory testing related to knee function, which will include hamstring strength assessment, hamstring tendon stiffness and muscle cross sectional area analysis via ultrasound. Participants will be assigned to one of three groups. Depending on group assignment, participants will either complete a 4-week knee flexor focused training program using a technique called blood flow restriction (BFR) therapy in one limb and normal high intensity training in the other limb (same exercises within each group), or will receive no treatment/intervention and complete normal daily activities. The BFR therapy intervention will consist of three sessions per week (twelve sessions total) that will focus on increasing hamstring strength. The first session will also include 1 repetition max testing for the exercises being completed during the intervention. Following the 4-week period, all participants will return to the laboratory to repeat similar laboratory testing. Comparisons of the data collected will be made between groups and limbs before and after the 4-week intervention period
Mark Colapietro at or 814-381-5093
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
All genders age 18-35
No history of significant knee pathology or lower extremity injury that required surgery in either limb
No history of hamstring strains or musculoskeletal injuries in past three months
No history of back pain in past 3 months
Physically active/ good general health
Exclusion Criteria:
History of lower extremity injury or fracture that required surgery
History of acute musculoskeletal injury in past 3 months for both limbs
History of hypertension (blood pressure greater than 130/80 mmHg), diabetes mellitus, compromised vascular circulation, or cancer
Individuals with neurological or other health condition that would limit their ability to flex the knee beyond 90 degrees
Participants with an allergic reaction to ultrasound gels
Sports Medicine, Muscle & Bone
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State College, PA