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Multimodal MR imaging of the midbrain for early Parkinson’s progression

This longitudinal MRI study aims to assess two novel MRI markers for early Parkinson's disease progression. Early stage Parkinson's patients, as well as healthy volunteers of similar ages, are eligible to be enrolled into the study.

Participants are asked to complete a screening, baseline and 12-month visit. During the baseline and 12-month visit, they are asked to complete some questionnaires as well as a motor evaluation, smell test and MRI. Participants also may choose to complete additional study components that may ultimately guide the diagnosis, prognosis and treatment of Parkinson's disease. These optional components include a fasting blood draw and collection of skin punch biopsies.

$500.00

Guangwei Du
Autumn Collier - at TBRC@pennstatehealth.psu.edu or 717-531-0003, ext=281168
 

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18 year(s) or older
This study is also accepting healthy volunteers
STUDY00014109
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Inclusion Criteria:
At least 35 years of age
Able to tolerate a brain MRI
Received initial diagnosis of Parkinson's disease within approximately the prior 3.5 years
Exclusion Criteria:
Older than 85 years of age
Condition that precludes a routine MRI, such as a pacemaker or severe scoliosis
Major medical problems, such as kidney or liver failure
History of cerebrovascular disease, such as a stroke
Intention to pursue deep brain stimulation (DBS) within the upcoming year
Neurology
Not applicable
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Location Contacts
Hershey, PA ,