Refine your search

Search Results

Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.

1 Study Matches

Home telemonitoring of bulbar function by acoustic measurement of swallowing and speech sounds in ALS

Most individuals with ALS experience changes in speech and swallowing over the course of the disease. In some, these are their initial indication of ALS. Identifying these changes, which may be rapid in some individuals, is complicated by the recent acceleration of virtual care delivery. This is a longitudinal home study of ALS patients to assess speech and swallowing function through use of smartphone application. The overall hypothesis is that this monitoring protocol can be used in a way that, 1) is satisfactory to the patient, 2) performs at least as well as standard clinical measures of dysarthria and dysphagia, and 3) resolves the development of emergence of speech and swallowing pathologies in ALS. Patients enrolling in this study will participate for approximately 24 weeks, during which they will have swallowing and speech tests performed, complete surveys, and perform audio recordings of speech on their cellphone. Healthy controls will be enrolled to judge the intelligibility of speech samples provided by patients in the study.
Cristie Crawford at or 814-863-5338
18 year(s) or older
This study is also accepting healthy volunteers
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
At least 18 years of age
Possess a diagnosis of amyotrophic lateral sclerosis (ALS)
Have symptom onset within the last 3 years
Demonstrate changes in speech or swallowing as a result of ALS.
Possess a smartphone capable of running the study application
Exclusion Criteria:
Possess a co-existing neurological or psychiatric illness in addition to their ALS diagnosis
Possess abnormal speech or swallowing processes due to a condition independent of their ALS diagnosis
Language & Linguistics, Neurology
  Email this study information to me
  Contact the study team
  See more information
  Show all 2 locations

Study Locations

Hide all locations
Hershey, PA
State College, PA