Refine your search

Search Results

Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.

1 Study Matches

A Phase II, Double-blind, Placebo-controlled, Randomized, Dose ranging, Parallel Group Study to Evaluate the Safety and Efficacy of PHA-022121 Administered Orally for Prophylaxis Against Angioedema Attacks in Patients with Hereditary Angioedema due to C1-Inhibitor Deficiency (Type I or Type II)

PHVS416 (PHA-022121 soft capsules) is being developed for the treatment of HAE. The main purpose of this research study is to test the effectiveness of different doses of study drug in preventing HAE attacks. Within this study, PHVS416 will be compared to a placebo.
Hunter Smith at
18 year(s) or older
This study is NOT accepting healthy volunteers
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Male or Female between the ages of 18 and 75 at the time of enrollement
Diagnosis of Heriditary Angioedema Type I or II
Must have had at least 3 HAE Attacks in 3 Months, or 2 HAE attacks in 2 months during screening period
Females must be willing to use highly effective contraception for the duration of the trial
Exclusion Criteria:
Diagnosis of any other chronic, recurrent angioedema
Participation in any other clinical trial in the 30 days prior to enrollment
Currently receiving any other prophylactic treatment for HAE and unwillingly to stop current medication
Infectious Diseases & Immune System, Allergies
  Email this study information to me
  Contact the study team
  See more information
  Show all 1 locations

Study Locations

Hide all locations
Hershey, PA