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Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.

5 Study Matches

Validation of Early Prognostic Data for Recovery Outcome after Stroke for Future, Higher Yield Trials (VERIFY)

The purpose of this research study is to understand how well we can predict your recovery by using tests done early after stroke. During the months after a stroke, some people recover all the way, some people don’t recover at all, and many people have a partial recovery. If we can predict how you will do in the coming months, we can choose the right rehabilitation therapies more quickly and more accurately.

Data will be collected during the acute hospitalization (in-person), at Day 30 (by phone), and at Day 90 (in person).

$190

Yes
 

Raymond Reichwein
Terri Smith - at tsmith@pennstatehealth.psu.edu or 717-531-6190
Neurology (HERSHEY)
 

All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT05338697
SITE00001220
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Inclusion Criteria:
Unilateral Stroke due to ischemic or intracerebral hemorrhage
Motor deficits in the acutely affected UE
Provision of signed and dated informed consent form within 48 to 96 hours of stroke onset
Stated willingness to comply with all study procedures and availability for the duration of the study
Fluent in English or Spanish

Exclusion Criteria:
UE injury or conditions on paretic side that limited use prior to the stroke
Legally blind
Dense sensory loss on paretic side indicated by a score of 2 on NIHSS sensory item
Unable to abduct the shoulder extend the fingers of the non-paretic UE on verbal command
Isolated cerebellar stroke
Neurology
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Hershey, PA ,

Asymmetries in Cognitive Aspects of Motor Control and Learning

This study will improve our understanding of movement control and how strokes of different sides affect overall independence. Participants will complete the visit seated at a chair with sensors connected to the less-affected arm. They will then play a short virtual reality game and complete several questionnaires and assessments.

Yes
 

Robert Sainburg
Shanie Jayasinghe - at sjayasinghe@pennstatehealth.psu.edu or 717-531-0003, ext=283146
Kinesiology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is NOT accepting healthy volunteers
STUDY00015871
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Inclusion Criteria:
Right handed (pre-stroke)
Neurological confirmation of unilateral stroke
Severe paresis on one side only
Adults over the age of 18
Chronic stage of stroke (>3 months post stroke)

Exclusion Criteria:
Left-handed (pre-stroke)
Neuro radiological confirmation of extensive periventricular white matter changes
History of neurological diseases other than stroke
Significant joint pain that is activity limiting
Neurology
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Hershey, PA ,

Predicting Ipsilesional Motor Deficits in Stroke with Dynamic Dominance Model

This study will test the hypothesize that the combination of low-moderate to severe paresis and persistent motor deficits in the non-paretic arm limits functional independence in chronic stroke survivors. We, therefore, predict that intense remediation, focused on improving the speed, coordination, and accuracy of the less-impaired arm should improve functional independence.

There will be two evaluation sessions, 15 training sessions, and 3 post-test evaluation sessions

$2,100

Yes
 

Robert Sainburg
Candice Maenza - at CMaenza@psu.edu or 717-531-0003, ext=283146
Kinesiology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03634397
STUDY00008385
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Inclusion Criteria:
Over the age of 18
Motor impairment in the arm
Had a stroke confirmed by neurology
Chronic stage of stroke

Exclusion Criteria:
neurological disease other than stroke
a major psychiatric diagnosis (e.g., schizophrenia, major affective disorder)
hospital admission for substance abuse
peripheral disorders affecting sensation or movement of the arms,
currently taking prescription drugs with known sedative properties that interfere with sensory-motor function
Neurology
I'm interested
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See this study on ClinicalTrials.gov
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Hershey, PA ,

Exploring the Concreteness Effect in Expressive and Receptive Language Measures in Healthy Aging as a Comparison for Persons with Aphasia

The concreteness effect is the finding that individuals are faster and more efficient at processing concrete words (e.g., "dog") than abstract words (e.g., "wisdom"). The study will investigate the presence and strength of the concreteness effect in neurologically intact older adults. This data will be used as a control comparison for a group of people with aphasia, a language disorder that commonly results from left hemisphere stroke.

Participants will be asked to complete language and cognition tests that measure attention, memory, problem solving, and language processing on the computer. Participants will be asked to complete two Zoom sessions, each lasting approximately 1.5 hours.

30

No
 

Anna Serrichio
Anna Serrichio - at acs36@psu.edu
Division of Graduate Studies (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023820
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Inclusion Criteria:
Native English Speaker
At least a high school education
40 years of age or older
Access to device with keyboard and internet connection to participate in Zoom sessions

Exclusion Criteria:
History of neurological, developmental, or psychiatric disorders
Below 40 years of age
Language & Linguistics
Not applicable
I'm interested
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Sound Symbolism and Aphasia

Sound symbolism is the idea that the sound of a word alone can convey its meaning. Aphasia is a language impairment, occurring most often as a result of a stroke. There is some evidence that sound-symbolic language is preserved in stroke patients. Studies in this protocol will investigate the extent to which this is so, and whether sound-symbolic language could be a rehabilitation strategy for aphasia.

We will ask you to listen to real words and non-words and make judgements about them. We may also ask you to complete some tests of language ability. The total time commitment may be up to four hours but will be split into two sessions.

Amount varies depending on the study

Yes
 

Krishnankutty Sathian
Josh Dorsi - at jdorsi@pennstatehealth.psu.edu
Neurology (HERSHEY)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00022919
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Inclusion Criteria:
Must be aged 18 or older
Must have English as your first language
Must have normal or corrected-to-normal vision
Must report normal hearing
May have a recent diagnosis of aphasia following a stroke

Exclusion Criteria:
Self-reported hearing difficulty
Bilingual persons may be excluded from some studies
Minors under the age of 18
Language & Linguistics
Not applicable
I'm interested
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Study Locations

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Hershey, PA ,