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329 Study Matches

An Innovative Approach for Assessing Interoception: A Pilot Validation Study

The primary rationale for this study lies in addressing the identified gaps in knowledge within the field of interoception research. A comprehensive understanding of interoception and its role in emotion regulation, behavior, and appetite control is vital for the development of effective interventions and therapeutic approaches targeting various psychological and physiological conditions. By investigating the applicability and accuracy of a novel method for assessing interoception, this study aims to contribute to the existing literature on interoceptive awareness and measurement.

This study will involve a single-in person visit. During the visit to the lab, we will weigh and measure you, have you complete two tasks assessing your ability to feel your own heartbeat, and answer questionnaires. For one of these tasks, you will be asked to complete Jumping Jacks. Throughout the session you will also be asked to wear a heartbeat monitor.

$10

Yes
 

Kathleen Keller
Nicholas Neuwald - at nvn5211@psu.edu or 814-863-0920
Nutritional Sciences (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00022855
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Inclusion Criteria:
Age of 18-30
Proficient in English
Adequate cognitive abilities

Exclusion Criteria:
Anxiety Disorder
Cardiovascular Health Conditions
Substance Use
Currently Pregnant
Sensory Impairments
Heart & Vascular, Neurology, Mental & Behavioral Health
Not applicable
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State College, PA ,

Incidence Rates of Hair Loss in Women Who Wear Hijab

The aim of this study is to obtain information regarding the incidence of hair-related concerns in women who wear hijab and to collect information pertaining to factors that could contribute to hair loss in women who wear the hijab.

This survey study will involve a one-time survey that will take 5-10 minutes.

No
 

Matthew Helm
Tierney Wallace - at twallace3@pennstatehealth.psu.edu or 717-531-6117
Dermatology (HERSHEY)
 

Female
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023070
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Inclusion Criteria:
Wear the hijab
Women
Read and understand English
Ages 18 years and older

Exclusion Criteria:
Do not meet inclusion criteria
Skin Conditions
Not applicable
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Interpersonal contrast avoidance of anxiety and depression

This research aims to learn more about your daily thoughts, behaviors, and their impact on social relationships. We want to understand the different qualities of day-to-day thoughts, how these might affect your mood, and how this may influence how you behave in social interactions. We will first ask you to complete a set of structured questionnaires and a brief 30-minute psychological interview via Zoom. This will be followed by a training session in which you will learn how to use your smartphone to track your social interactions and related daily thoughts and behaviors eight times a day for eight days.

You will undergo an initial assessment visit conducted on Zoom, where you will provide informed consent and undergo screening through a brief 30-minute clinical interview. Based on your responses, we will know if you can participate in the study. If eligible, you will be invited to the second part of the study. If so, during the same session, you will then receive a brief half-hour training session reviewing instructions on using a mobile application to complete daily surveys and then complete a series of online questionnaires.When you leave this session, for the next eight days, you will complete eight (approximately 2-minute) questionnaires daily between 10 a.m. and 10 p.m. On the third day, you will attend a compliance check via Zoom to review your progress in the present study.

$20

Yes
 

Adam Calderon
Adam Calderon - at afc6160@psu.edu
Psychology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00022977
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Inclusion Criteria:
At least 18 years of age
Scores on self-report questionnaires suggest person does or does not struggle with anxiety and/or depression
Owns a smartphone
Fluent in the English language in terms of speaking, listening, reading, and writing.

Exclusion Criteria:
Younger than 18 years of age
Does not own a smartphone
Unable to speak, read, listen, and write English fluently.
Men's Health, Mental & Behavioral Health, Women's Health
Not applicable
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State College, PA ,

Use of the Frequen-ZZZ Sleep Pad to Increase Restorative Sleep: A Proof-of-Concept Study

This research is a small, 8wk clinical trial testing the potential effects of an investigational device, Frequen-ZZZ/Sleepergize Sleep Pad, on the sleep of adults 40-65 years old. We aim to determine whether sleeping with the Sleep Pad, which creates an electromagnetic field around the sleeper, has an improving effect on sleep. Sleep will be primarily measured using a non-invasive clinical standard method, called polysomnography (PSG), for 6 separate nights in the personal residence of participants. Sleep will also be measured both day and night with a watch-like device that measures activity, and with surveys. We will look for changes in sleep quality, in sleep duration, and in the way that sleep is organized by the body. We will also measure changes in inflammation, which is related to sleep, from 3 blood samples collected during the study. There are 15-17 in-person appointments across the course of the study. With the data, we hope to also evaluate the feasibility and effect sizes of this non-pharmacological intervention to inform future research, and we plan to use data in support of a future FDA application for the device.

Participation involves sleeping with the investigational device, 6 separate nights of sleep monitoring in your home with standard equipment that is used in clinical settings, 3 blood draws, surveys, and wearing an activity watch, all over the course of an ~8wk participation period. There are 15-17 in-person appointments and about 15 active hours of engagement involved in the study.

$3,000.

Yes
 

Anne-Marie Chang
Anne-Marie Chang - at sleeppad@psu.edu
Biobehavioral Health (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
NCT05908344
STUDY00020435
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Inclusion Criteria:
40-65 years of age (inclusive)
At least some Insomnia symptoms
Living without assistance and able to sign own informed consent
Not a nocturnal shift or rotating shift-worker
English speaker/reader

Exclusion Criteria:
Current smoker
Diagnosed with a sleep disorder
Pacemaker
Pregnant, breast-feeding, or planning to become pregnant
Taking prescribed medication or therapy for sleep
Men's Health, Sleep Management, Women's Health
Experimental device
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State College, PA ,

Can more sleep improve pain responses, symptomatology, and regulation in college students?

This study is being done to find out how whether sleep duration is associated with pain responses and if a sleep intervention predicts a higher tolerance and a higher threshold for pain. This is a 21-day study. Participants will be asked to wear sleep-monitoring watches. Pressure pain and cold pain will be measured at study visits.

There will be four in-person visits. Height, weight, and blood pressure will be measured during each study visit. Participants will also be asked to complete surveys during each study visit.Pain will be measured during visits 2-4. Blood will be drawn during visits 2-4. Retinal images will be captured during visits 2-4. A Trail making test (a test for executive functioning) will be administered during visit 2-4. Participants will also be asked to provide screen shots of their phone screen use at visits 2-4.

$150

Yes
 

Anne-Marie Chang
yms5393@psu.edu 814-867-1653
Biobehavioral Health (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
NCT05816434
STUDY00022196
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Inclusion Criteria:
18 to 24 (inclusive) years of age at enrollment
Fluent English speaker and reader
Willing to refrain from initiating new therapeutic interventions (e.g., medication; behavioral) designed to target sleep or pain for the duration of study participation

Exclusion Criteria:
Diagnosed with a sleep disorder
Diagnosed with a pain disorder
Has experienced a cold-related injury or has any other nerve damage to the feet
Has a history of injury to any of the muscular measurement sites for pain (I.e. shoulder, jaw, forearm)
Diagnosed with hypertension or cardiovascular disease
Prevention
Not applicable
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State College, PA ,

PSCI 23-020: EA8212 A Randomized Phase III Trial of Intravesical BCG veRsus Intravesical Docetaxel and GEmcitabine Treatment in BCG Naïve High Grade Non-Muscle Invasive Bladder Cancer (BRIDGE)

If you decide to take part in this study, you will either get Gemcitabine and Docetaxel instilled through a catheter weekly in your bladder for up to 6 weeks, or you will get BCG instilled weekly in your bladder for up to 6 weeks. Your initial therapy may be followed with maintenance therapy.

If you decide to take part in this study, you will either get Gemcitabine and Docetaxel instilled through a catheter weekly in your bladder for up to 6 weeks, or you will get BCG instilled weekly in your bladder for up to 6 weeks. Your initial therapy may be followed with maintenance therapy.After you finish your treatment, your doctor will continue to follow your condition for 5 years with a combination of cystoscopies (inserting a telescope in your bladder) and CT scans (to take images of your body) in order to detect cancer recurrence.

Yes
 

Matthew Kaag
PSCI CTO Office at psci-cto@pennstatehealth.psu.edu or 717-531-5471
Urology (HERSHEY)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
NCT05538663
SITE00001374
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Inclusion Criteria:
Patient must be > 18 years of age.
Patient must have histologically confirmed high-grade non-muscle invasive urothelial carcinoma of the bladder (HgTa, HGT1, CIS, HgTa + CIS, or HGT1 + CIS stage)
Patient must have ECOG Performance Status 0-2.
Patient must have all visible papillary tumor resected by the treating urologist at the site registering the patient to this protocol prior to randomization.
Patient may have received prior systemic gemcitabine or docetaxel use if it was for a non-bladder malignancy

Exclusion Criteria:
Patients must not have prostatic urethral involvement
Patient must have not received prior intravesical therapy for bladder cancer, with the exception of perioperative chemotherapy at the time of TURBT.
Patient must not have pure squamous cell carcinoma or adenocarcinoma.
Patient must not have any component of neuroendocrine carcinoma (i.e., small cell or large cell).
Patient must not have any component of sarcomatoid, micropapillary, or plasmacytoid variant histology.
Kidney & Urinary System
Experimental drug compared to an approved drug
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Hershey, PA ,

One Talk at a Time - Anti-Racism

This is a psychological study to examine the effect of a new intervention that provides parents with tools to speak with their kids about race, racism, and privilege.Participants will complete a 2-3 hour long program and answer questionnaires over the course of 6-8 weeks. The total time required for this study is approximately 4.5 hours for parents and 2 hours for children. Parents can earn up to $165 and children can earn up to $50.

Parents and children will both be asked to participate, and all participation will be remote.Over the course of 6-8 weeks, parents will answer 3 sets of questionnaires in addition to completing 2-3 hour long interactive program. Parents will also be asked to participate in a recorded discussion task with their child, and will be invited back for a short interview as the final task.Children will answer 2 sets of questionnaires at the beginning and end of the study, and will also participate in the recorded discussion task with their parents.

215

No
 

Chardee Galan
Chardee Galan - at dreamlab@psu.edu or 626-205-5563
Psychology (UNIVERSITY PARK)
 

All
All
This study is also accepting healthy volunteers
STUDY00023214
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Inclusion Criteria:
Non-Hispanic, White parent and child
Child between the ages of 10-14 years old
Child in 5th through 8th grade
Parent and youth are fluent in English
Parent and youth have access to devices with WiFi

Exclusion Criteria:
Parent or youth identify as any race/ethnicity other than non-Hispanic White, including multiracial individuals that identify as White
Family does not have reliable internet access or access to a device that can appropriately display the virtual program.
Parent or children does not speak or read sufficient English
Youth or parent/caregiver has an intellectual disability, autism spectrum disorder, or other disorder that may limit ability to complete study (surveys and interviews require sustained attention, mental processing, and comprehension)
Children's Health, Education, Mental & Behavioral Health
Not applicable
I'm interested
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Modifiable Prevention and Early Intervention Targets for Unhealthy Eating Behaviors: A Study in First Year Undergraduates

This is a research study investigating the prevalence and manifestation of unhealthy eating behaviors and the relationships of energetic status, cognitive function, and reproductive health in a population of first year college students.

Phase 1 will involve a minimum of 1-2 visits, and completion of surveys about your general health, exercise and nutrition history, eating behaviors and attitudes, stress, and reproductive health, as well as cognitive testing and hair sampling. For those who qualify, Phase 2 will involve approximately 4 additional visits. Each visit will be about 2 hours. The visits include completion of surveys about general health, exercise and nutrition history, eating behaviors and attitudes, stress, and reproductive health, as well as cognitive testing and physiological measurements including blood and hair sampling, and tests of metabolism. Study participation will last at minimum about 1 week, and at maximum completion of Phase 1 and Phase 2 will occur over the course of a full academic year.

$25 per visit, up to $75

Yes
 

Nancy Williams
Jaime Rodden - at whel@psu.edu
Kinesiology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00022878
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Inclusion Criteria:
First Year College Student
Age 18-25 Years
BMI 16.5-30 kg/m2
No apparent metabolic, endocrine, or musculoskeletal disease.

Exclusion Criteria:
Pregnancy or intention to become pregnant in the next 9 months
Serious or chronic health condition (including thyroid illness, metabolic disease)
Unwilling to adhere to study protocol
Lactating
Does not speak English or are unable to give consent
Men's Health, Mental & Behavioral Health, Women's Health
Not applicable
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State College, PA ,

Defining the role of slow eye movements on limb motor control

The purpose of this study is to define how eye movements contribute to eye-hand coordination. All procedures to be used in our study will be non-invasive. The task during the study will be performed with a robotic handle that participants will grasp with their right hand. They will interact with visual stimuli by moving the robotic handle. The robotic environment will attempt to simulate real-world mechanical interactions, such as those experienced during catching a ball. Our objective is to understand how the nervous system processes visual sensory information of moving objects through slow eye movements called smooth pursuit eye movements.

During this study, we will ask you to come to our laboratory located in 23 Recreation Building, Penn State University, on two days separated by a maximum of 48 hours. Both sessions will last approximately 90-120 minutes.We will ask you to perform an eye-hand coordination task using a robot. You will sit in a modified chair and grasp a handle that permits you to move your hand leftward, rightward, towards and away from your body. A display system will project visual targets into the same plane as your hands, which will allow you to interact virtually with the visual targets. These targets will move in the workspace. When the target comes in contact with your arm, the robot will apply a gentle force to mimic what you would typically experience when you catch a ball.

40

Yes
 

Tarkeshwar Singh
Oindrila Sinha - at osinha@psu.edu or 814-206-6260
Kinesiology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023321
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Inclusion Criteria:
Participants should be between 18-65 years old.
Male and female participants who volunteer for the study and provide informed consent.
Participants will be right-hand dominant individuals.
They will have normal or corrected-to-normal vision.
Participants should be able to sit upright in a chair for long periods (up to 2 and a half hours) with rest.

Exclusion Criteria:
Any history of neurological disorders
Any history of musculoskeletal disorders.
Eye or vision problems.
Cognitive impairment such that informed consent cannot be obtained, or that participant would not be safe with the protocol.
Medication that could make the participant drowsy or tired during the experiment.
Neurology
Not applicable
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Study Locations

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State College, PA ,

Exploring the Needs and Challenges of Care Partners to Support Financial Management of Individuals with AD/ADRD

The project focuses on gathering initial evidence about the opportunities and challenges of designing tailored financial technology (fintech) to support the care partners of persons living with Alzheimer’s disease (AD) and AD-related dementia (ADRD) to help them with collaborative and longitudinal financial management. To accomplish this goal, we will conduct 20 min survey study and optional follow-up interview activities with care partners.

We are recruiting care partners of individuals living with Alzheimer's Disease and Alzheimer's Disease Related Dementias. There will be two phases in the study. The first phase is a 20-min survey that will ask participants about their financial management behavior. The second phase is optional, and it is a 40-min follow-up interview with similar questions.

For the first phase, each participant may choose to enter a drawing for a chance to win a $50 Amazon eGift card. For the second phase, each participant will receive a $30 Amazon eGift card for their time.

No
 

Ling Qiu
Ling Qiu - at lzq5034@psu.edu or 402-416-5975
Information Sciences and Technology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023385
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Inclusion Criteria:
Care partners of individuals living with Alzheimer's Disease and Alzheimer's Disease Related Dementias
Ability to understand or speak English
Age range: over 21 years and less than 89 years.

Exclusion Criteria:
Minors, under age 21
Non-English-speaking respondents
Those who are NOT care partners of individuals living with Alzheimer's Disease and Alzheimer's Disease Related Dementias
Mental & Behavioral Health
Survey(s)
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The role of thromboxane A2 and its receptor in vascular regulation in women with endometriosis

Women with endometriosis have more thromboxane being produced in their platelets. Thromboxane affects blood vessels, making them constrict, and sensory nerves, making them more sensitive. This study will determine if women with endometriosis are negatively effected by the excess thromboxane.

There will be three in-person visits: one screening and two experimental visits. Participants will take aspirin before one visit and a placebo before the other then will undergo brief tests of nerve sensitivity and a blood draw.

$150

Yes
 

Lacy Alexander
Sue Slimak - at sks31@psu.edu or 814-863-8556
Kinesiology (UNIVERSITY PARK)
 

Female
18 year(s) or older
This study is also accepting healthy volunteers
NCT05962034
STUDY00021851
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Inclusion Criteria:
18-48 years
born with a uterus
with and without endometriosis

Exclusion Criteria:
diagnosed cardiovascular disease
hormone replacement therapy within previous 2 months
nicotine use
pregnant or breastfeeding
aspirin allergy or hypersensitivity
Heart & Vascular, Pain Management, Women's Health
Approved drug(s)
I'm interested
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Study Locations

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Hershey, PA ,
State College, PA ,

Dynamic Assessment of Vocabulary Learning Strategies

To provide better understanding of Chinese students' vocabulary learning Strategies and help develop better learning strategies

Complete seven sessions, which may take approximately 20-30 minutes of your time per session.Read several English short texts and identify meanings of target words.Possibly participate in a virtual interview that will be scheduled at your convenience.

No
 

Yuwei Xia
Yuwei Xia - at yxx5304@psu.edu or 626-999-1712
Division of Graduate Studies (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00021134
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Inclusion Criteria:
Of Chinese origin or descent
Adult English learners
Currently enrolled in a college or university

Exclusion Criteria:
English as Native Language
Not Chinese
Education
Not applicable
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Dynamic Assessment of English Vocabulary

Better understand and improving Chinese English learners' vocabulary development

•Complete seven sessions, which may take approximately 20-30 minutes of your time per session.•Read several English short texts and identify meanings of target words.•Possibly participate in a virtual interview that will be scheduled at your convenience.

No
 

Yuwei Xia
Yuwei Xia - at yxx5304@psu.edu
Division of Graduate Studies (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023081
Show full eligibility criteria
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Inclusion Criteria:
Of Chinese origin or descent
Adult English learners
Currently enrolled in a college or university

Exclusion Criteria:
English as native language
Education
Not applicable
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Home Observation of Meals and Environment (HOME) Bytes

This study aims to measure child eating behavior at home. Parents will video record their child eat 3 meals at home using a smart phone device and then take pictures of food storage locations (e.g., fridge, pantry). Videos will be coded for child eating behaviors. Parents will complete baseline and follow-up questionnaires. Children will wear an activity watch (like a Fitbit) for 1 week. In addition to these study procedures, there is an optional urine sample collection for children in order to study urinary metabolites as a marker of diet.

You will be asked to video record your child eating 3 meals at home and to take photos of food storage locations in your home (e.g., fridge, pantry).

$75 and an optional $25 for completing the urine sample collection

No
 

Alaina Pearce
Alaina Pearce - at homebytes@psu.edu
Nutritional Sciences (UNIVERSITY PARK)
 

All
Younger than 18 years old
This study is also accepting healthy volunteers
STUDY00023102
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Inclusion Criteria:
Child must be of good health
Child must have no neurodevelopmental disorder (e.g., ADHD) or learning disabilities (e.g., dyslexia)
Child must not be taking any medications known to influence body weight, taste, food intake, behavior, or blood flow.
Child must be 7-10 years-old at enrollment
The child must speak English

Exclusion Criteria:
Child is not within the age requirements (< than 7 years old or > than 10 years-old at baseline).
Child is taking cold or allergy medication, or other medications known to influence cognitive function, taste, appetite, or blood flow.
Child has a learning disability, ADD/ADHD, language delays, autism or other neurological or psychological conditions.
Child has a pre-existing medical condition such as type I or type II diabetes, rheumatoid arthritis, Cushing’s syndrome, Down’s syndrome, severe lactose intolerance, Prader-Willi syndrome, HIV, cancer, renal failure, or cerebral palsy.
Child has a highly restrictive diet limiting their ability to consume typical meals due to disordered eating (anorexia, RFID) or severe allergies.
Children's Health, Food & Nutrition
Not applicable
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Singlehood in the Emerging Adult Years: The use of Technology to Communicate

The goal of this study is to understand the use of dating apps in emerging adults (ages 18-29 years old). Using an online survey, participants will be asked a series of questions about their well-being, romantic relationship history, and about their use of dating apps.

You will be asked to take a brief, 15-25 minute online survey, and you may be asked to upload a few screenshots from your phone.

No
 

Nicole Watkins
Nicole Watkins - at nkw5323@psu.edu or 570-963-2573
Social Sciences and Education (SCRANTON)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023596
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Inclusion Criteria:
1.Must be between the ages of 18-29
2.Must be fluent in English
3.Reside in the US
4.Must self-identify as single (romantic relationship status) at the time of participation
5.Must own and use an IPHONE

Exclusion Criteria:
1.Adults over the age of 29
2.Children under age 18
3.Those who do not have an IPHONE
4.Not fluent in English
5.Do not self-identify as single at the time of participation (romantic relationship status)
Men's Health, Mental & Behavioral Health, Women's Health
Not applicable
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Investigation of Digital Media Use, Anxiety, and Biobehavioral Emotion Regulation in Adolescents

Over the past few decades, the social world of teens has been transformed by the use of digital technology. This study will examine associations between digital media use and emotions in adolescents' daily lives.Youth and their parent will complete questionnaires and semi-structured clinical interviews regarding the youth’s emotions, social experiences, and possible anxiety symptoms. For 10 consecutive days, youth will complete one computerized task once per day and four mini questionnaires via the Wear-It app on the youth's mobile device.Some youth will also participate in a lab visit that will last approximately two hours. Six months later, all youth will be asked to repeat one computerized task once per day and four mini questionnaires via the Wear-It App on the youth's mobile device.One year after enrollment, participants will complete final questionnaires, interviews, one computerized task once per day and four mini questionnaires via the Wear-It App on the youth's mobile device. Some youth will also participate in a lab visit that will last approximately two hours.

Over the past few decades, the social world of teens has been transformed by the use of digital technology. This study will examine associations between digital media use and emotions in adolescents' daily lives.Youth and their parent will complete questionnaires and semi-structured clinical interviews regarding the youth’s emotions, social experiences, and possible anxiety symptoms. For 10 consecutive days, youth will complete one computerized task once per day and four mini questionnaires via the Wear-It app on the youth's mobile device.Some youth will also participate in a lab visit that will last approximately two hours. Six months later, all youth will be asked to repeat one computerized task once per day and four mini questionnaires via the Wear-It App on the youth's mobile device.One year after enrollment, participants will complete final questionnaires, interviews, one computerized task once per day and four mini questionnaires via the Wear-It App on the youth's mobile device. Some youth will also participate in a lab visit that will last approximately two hours.

$495

No
 

Sarah Myruski
Stacey LeVan - at sls217@psu.edu or 814-863-6485
Psychology (UNIVERSITY PARK)
 

All
All
This study is also accepting healthy volunteers
NCT00000000
STUDY00023358
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Inclusion Criteria:
Youth age 14-16.9 with a parent
Speak, write and read English
Must reside and participate from the US

Exclusion Criteria:
Not able to speak, write or read in English
Neurological disorders (ie, Autism, seizures)
Youth of parent not between 14-16.9 years of age
Those not residing in or participating from the US
Mental & Behavioral Health
Not applicable
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The role of ocular and limb motor inhibition for dexterous motor control

In this project, participants will perform experiments where they will be asked to look at salient virtual targets and make reaching movements to those targets, while ignoring other visual stimuli presented to them.

During this study, we will ask you to come to our laboratory located in 23 Recreation Building, Penn State University, on a single day.We will ask you to perform an eye-hand coordination task using a robot. You will sit in a modified chair and grasp a handle that permits you to move your hand leftward, rightward, towards and away from your body. A display system will project visual targets into the same plane as your hands, which will allow you to interact virtually with the visual targets. These targets will be either bright or dark and you will be instructed to look at some of these targets (while ignoring others) and make reaching movements to some of these targets.

20

Yes
 

Tarkeshwar Singh
Tarkeshwar Singh - at tsingh@psu.edu
Kinesiology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023552
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Inclusion Criteria:
Participants should be between 18-50 or 65-80 years of ageold.
Male and female participants who volunteer for the study and provide informed consent.
Participants will be right-hand dominant individuals.
They will have normal or corrected-to-normal vision.
Participants should be able to sit upright in a chair for long periods (up to 2 and a half hours) with rest.

Exclusion Criteria:
Any history of neurological disorders
Any history of musculoskeletal disorders
Eye or vision problem
Cognitive impairment such that informed consent cannot be obtained, or that participant would not be safe with the protocol.
Medication that could make the participant drowsy or tired during the experiment
Neurology, Vision & Eyes
Not applicable
I'm interested
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Study Locations

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State College, PA ,

Exploring Gender Differences in ADHD Through Narrative Competency

This is an interview study that will examine how people with and without ADHD tell stories. Eligible participants will be asked to attend a virtual televisit where they will tell three stories according to prompts given by study staff. We are recruiting both men and women for this study so we can determine if gender affects storytelling ability.

There will be one virtual visit on Zoom lasting approximately one hour. Participants will complete eligibility questionnaires, then eligible participants will be asked to tell three stories based on prompts from an investigator and complete one additional questionnaire.

$15

No
 

Grace Smith
Grace Smith - at ges5315@psu.edu
Division of Undergraduate Studies (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023413
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Aged 18-30
Diagnosis of Attention-Deficit Hyperactivity Disorder (ADHD)
No diagnosis of Attention-Deficit Hyperactivity Disorder (ADHD)
Native English speaker

Exclusion Criteria:
Diagnosed or suspected Autism Spectrum Disorder (Autism, ASD, previously known as "Asperger's Syndrome")
Under 18 or over 30 years old
Psychosis, dyslexia, or other neurological impairment
Uncorrected hearing loss
Neurology, Mental & Behavioral Health, Language & Linguistics
Not applicable
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Rapid Motor Regulation Mechanism for Arm Movement in Response to Visual Motion

This study looks at the relationship between motor control via. arm movement and visual stimuli. After participating in brief calibration protocol for the eye tracking system, participants will be moving a robotic handle to interact with visual stimuli during various tasks. Participants will spend approximately 2 hours in the lab.

There will be one approximately 2-hour visit. They will then be asked to complete 20-25 blocks of hand movements while looking at a moving virtual stimulus with a large visual background. Participants will receive regular breaks during the experiment.

$20

Yes
 

Tarkeshwar Singh
Tarkeshwar Singh - at tsingh@psu.edu or 814-865-7851
Kinesiology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023522
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Inclusion Criteria:
Between 18-65 years old
Right-hand dominant
Normal or corrected-to-normal vision
Able to sit upright in a chair for long periods
Able to grasp and move objects with both hands

Exclusion Criteria:
Any history of neurological disorders
Any history of musculoskeletal disorders
Eye or vision problems (e.g., cataracts, glaucoma, a detached retina or macular degeneration)
Cognitive impairment such that informed consent cannot be obtained, or that participant would not be safe with the protocol
Medication that could make the participant drowsy or tired during the experiment
Neurology, Vision & Eyes
Not applicable
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State College, PA ,

Validation of Cell-free mitochondrial DNA (cf-mtDNA) Saliva Collection Methods

The reproducibility, reliability, and validity of saliva collection techniques is an important issue that needs to be addressed to achieve consistency in the emerging field of mitochondrial psychobiology. The objective of the current study is to increase scientific rigor by utilizing robust and well-controlled methods in the collection and testing of saliva samples. Given the non-invasive and convenient nature of saliva collection, it is likely that research using saliva-derived cell-free mitochondrial DNA (cf-mtDNA) will increase. Therefore, to ensure that the results obtained from the current study are trustworthy and meaningful, we are proposing a small, highly controlled randomized study design that will integrate three methods of saliva collection. The study will adopt a rigorous and systematic approach to data collection, analysis, and interpretation. Through the implementation of these methods, we seek to achieve a higher degree of accuracy and reliability in cf-mtDNA saliva-based measurements.

Each participant will be asked to collect 3 randomized saliva samples (i.e., one static Salivette®, one active Salivette®, and either a second active Salivette® or a passive drool) upon awakening for 10 business days. All collection materials be pre-labeled with the day, type of sample, and order to make it easy for participants to quickly and accurately deposit samples upon awakening. Once saliva samples are collected, participants will be asked to promptly return the samples to the provided plastic bag and store the bag in their at-home freezers. All samples will be stored there until the end of the 10-day study. After the saliva is returned to the freezer, participants will complete a short (3-5 min) morning survey on the provided mobile device which has been pre-loaded with the M2C2 application. The morning survey asks questions about sleep, morning outlook, and anticipatory stress and positive experiences. In the evenings, participants will be prompted (via banner notification on screen and audible beep) to complete a slightly longer (8-10 min) survey. This survey asks questions about the respondent’s daily experiences (stressors, mood, physical symptoms). Within the application, there are three brief, objective cognitive tasks. Upon completion of the 10-day protocol, respondents will return the mobile device and saliva samples. Participants may bring all saliva samples back to the lab during regular business hours, or they may schedule a time for a member of the study team to pick up the samples. Depending on the distance between the laboratory and the participant’s home, the need for ice packs will be assessed on an individual basis.

50

Yes
 

Idan Shalev
Lauren Petri - at laurenpetri@psu.edu
Biobehavioral Health (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023371
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Inclusion Criteria:
healthy adult
between the age of 18-50 years
must be English speaking
cannot be pregnant or breastfeeding
must not use tobacco

Exclusion Criteria:
Younger than 18
Individuals who work nightshift
Individuals who do not have access to an at-home freezer
Individuals who have an irregular sleep-wake cycle
Individuals who currently use tobacco
Infectious Diseases & Immune System, Mental & Behavioral Health
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State College, PA ,

To stretch, not strain: Impact of passive stretching on calf muscle and gait mechanics in peripheral artery disease

People with narrowed blood vessels in their legs can only walk a short distance before needing to sit down due to pain in their calf muscles. Most of these patients do not follow their heart doctor's advice to walk at home because it hurts. A therapy that does not involve painful walking would be ideal for these patients to begin to treat their disease so they can eventually walk with less discomfort. We will ask patients with peripheral artery disease (PAD) to place both feet into inflatable ankle splints 30 minutes a day for 4 weeks to passively stretch their calf muscles. Before and after this 4-week program, we will measure the health and size of their leg blood vessels, the length, and function of their calf muscles and tendons, and how long they can walk without pain. We will also closely track their joint and foot movements and calf muscle oxygen levels while they walk down a hallway. People with and without risk factors for heart disease are also eligible for this study to compare differences in vascular and muscular health to patients with PAD. Volunteers without a PAD diagnosis or poor leg circulation will not undergo the 4-week stretch and no-stretch interventions.

Peripheral artery disease (PAD) and poor leg circulation patients:-4 visits to University Park Clinical Research Center ~3 hours per visit-1 blood draw-Wear a calf muscle stretching device for 30-min a day, 5 days a week, for 4 weeks and 4 weeks of no stretching-Several muscle and vascular ultrasound measurements-Walking performance tests on and off the treadmill-Wear a smartwatch to monitor physical activity during each 4-week stretch or no stretch interventionParticipants with and without risk factors for heart disease:-2 visits to University Park Clinical Research Center within the same week lasting ~3 hours per visit-Not diagnosed with PAD or poor leg circulation-1 blood draw-Several muscle and vascular ultrasound measurements-Walking performance tests on and off the treadmill

PAD participants can receive up to $450 in compensation. Participants with and without heart disease risk factors (non-PAD participants) will receive $50 for their participation.

Yes
 

David Proctor
Jocelyn Delgado - at proctorlab@psu.edu
Kinesiology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
NCT06041880
STUDY00022960
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Inclusion Criteria:
Patients (40-85 years) diagnosed with peripheral artery disease or poor leg circulation
Participants (20-85 years) with or without risk factors for heart disease (high blood pressure, blood sugar, cholesterol, etc.) and not diagnosed with PAD
Ability to walk on or off a treadmill at 1 mile per hour
Men and women who are not pregnant or nursing

Exclusion Criteria:
Current tobacco smoker or use of nicotine-containing products
Heart attack within the past 6 months or unstable angina
Severe lung disease, rheumatoid arthritis, degenerative joint disease, critical limb ischemia
Major surgery or lower extremity revascularization surgery within the past 6 months
Recent serious ankle, Achilles tendon, or foot injuries
Heart & Vascular, Muscle & Bone
Experimental device
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Altoona, PA ,
State College, PA ,

Neurobehavioral Effects of Frequent Co-use of Alcohol and Cannabis

This study will examine neural reactivity to stress in young adults who use alcohol and cannabis and link these responses to behaviors in everyday life.

You will be asked to complete the following:1) An in-lab intake appointment for interviews and questionnaires2) An in-lab neuroimaging training session and scan + smartphone-based training session3) Three separate 14-day bursts (total of 42 days) of smartphone-based reporting in daily life4) A follow-up visit after the first 14-day burst5) 6-month follow-up appointment for interviews and questionnaires6) 12-month follow-up appointment for interviews and questionnaires

717

Yes
 

Eric Claus
Skylar Lin - at repeatlab@psu.edu or 814-865-9939
Biobehavioral Health (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023420
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Inclusion Criteria:
18-30 years old
Use an android or apple smartphone
Cannabis use
Alcohol use
Willing to do MRI scan

Exclusion Criteria:
Women who are pregnant or lactating
Inability to give informed consent
Any contraindications for MRI (e.g., medical devices in the body, claustrophobia, etc.)
Mental & Behavioral Health
Not applicable
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State College, PA ,

Advancing the use of immersive virtual environments to study the effects of racism on eating behavior in an Asian American population

During the COVID-19 pandemic, Asian Americans have faced a rise in overt racism, with thousands of hate incidents reported. This has had a bigger impact on young Asian American adults, leading to emotional distress and health problems. A theory by Harrell suggests that experiencing racial discrimination can harm mental and physical well-being due to stress. Past studies have shown a connection between racial discrimination stress and health issues like obesity and mental disorders. However, there's a need to understand the cultural and emotional factors involved. This research aims to explore how racial discrimination affects Asian Americans' food choices by looking at stress responses and cultural influences. Using surveys, experiments, psychophysiology, and virtual reality, the study will investigate how cultural identity affects stress reactions and subsequent food decisions after racial discrimination experiences.

Hello,We are recruiting Asian Americans with Japanese, Chinese, or Korean heritage for a paid research study.We want to understand how racism affects food choice in a virtual reality (VR) environment. To participate in this study, you will need to complete an informed consent form, and answer questions prior to your arrival at the lab. You will have to come to the lab to watch a video of anti-Asian racism incidents that happened during the COVID-19 pandemic, and answer questions before and after the video. Last, you will make food choices in the VR environment. Participation will require three hours or more of fasting before arrival at the lab.You will be paid $25 in a gift card for your participation. If you come to the lab but do not complete the study, you will still be paid.Please continue to the next page to read the informed consent if you are interested in participating. If you are not, please exit this page.&lt;&lt;LINK TO REDCap SURVEY HERE&gt;&gt;

$25 gift card

Yes
 

Travis Masterson
Bianca Braga - at bqc5625@psu.edu
Nutritional Sciences (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
NCT00000000
STUDY00023365
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Inclusion Criteria:
Self-identified as Asian American of Japanese, Chinese or Korean heritage
Aged between 18 and 21 at the start of the study
Born in the US
Self-reported having fasted for at least 3 hours prior to the start of the study

Exclusion Criteria:
Not self-identified as Asian-American of Japan, China or Korea heritage
Not aged between 18 and 21 at the start of the study
Not born in the US
Self-reported having fasted for less than 3 hours prior to the start of the study
Has epilepsy or a cognitive disability
Food & Nutrition, Mental & Behavioral Health
Not applicable
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State College, PA ,

The effects of creatine supplementation on neurocognitive function of college students of differing levels and types of physical activity

This study design is a survey that collects information about students' active level and supplement use, with an emphasis on creatine. The difference between contact and non-contact athletes will be examined, in addition to people who are considered inactive/low activity. This will help provide information of how physical activity related supplementation use affects cognition in different populations, with varying amounts of neurotrauma.

All participants will complete a digital survey that provides information about their dietary supplementation and physical activity habits. As part of the survey, participants will be allowed to indicate their interest and availability to come to a laboratory setting to complete a brief batter of neurocognitive tests.

Yes
 

Semyon Slobounov
Bogdan Ivanov - at bmi5063@psu.edu or 617-327-4064
Kinesiology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023261
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Inclusion Criteria:
18 years or older

Exclusion Criteria:
Under 18 years of age
Has had concussion in last 3 months
Food & Nutrition, Sports Medicine
Survey(s)
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State College, PA ,

Intraparticipant speaking rate differences within and across sessions

The purpose of this study is to assess if healthy adults speak at a consistent speaking rate when asked to read a standard passage or answer an open ended prompt.

There will be 2 visits that each take approximately 20 minutes. We will meet in person or via Zoom. At each visit you will be asked to read three paragraphs and answer some open ended questions/prompts.

No
 

Nicole Etter
Nicole Etter - at oppal@psu.edu
Communication Sciences and Disorders (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023863
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Inclusion Criteria:
18 years or older
English-speaking
Hearing and cognition within functional limits to complete speaking tasks

Exclusion Criteria:
Currently seeking treatment for speech or voice concerns
History of neurologic disease, injury, or event including traumatic brain injury, stroke, multiple sclerosis, amyotrophic lateral sclerosis, Parkinson’s disease, etc.
Language & Linguistics
Not applicable
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Exploring the Concreteness Effect in Expressive and Receptive Language Measures in Healthy Aging as a Comparison for Persons with Aphasia

The concreteness effect is the finding that individuals are faster and more efficient at processing concrete words (e.g., "dog") than abstract words (e.g., "wisdom"). The study will investigate the presence and strength of the concreteness effect in neurologically intact older adults. This data will be used as a control comparison for a group of people with aphasia, a language disorder that commonly results from left hemisphere stroke.

Participants will be asked to complete language and cognition tests that measure attention, memory, problem solving, and language processing on the computer. Participants will be asked to complete two Zoom sessions, each lasting approximately 1.5 hours.

30

No
 

Anna Serrichio
Anna Serrichio - at acs36@psu.edu
Division of Graduate Studies (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023820
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Inclusion Criteria:
Native English Speaker
At least a high school education
40 years of age or older
Access to device with keyboard and internet connection to participate in Zoom sessions

Exclusion Criteria:
History of neurological, developmental, or psychiatric disorders
Below 40 years of age
Language & Linguistics
Not applicable
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Sound Symbolism and Aphasia

Sound symbolism is the idea that the sound of a word alone can convey its meaning. Aphasia is a language impairment, occurring most often as a result of a stroke. There is some evidence that sound-symbolic language is preserved in stroke patients. Studies in this protocol will investigate the extent to which this is so, and whether sound-symbolic language could be a rehabilitation strategy for aphasia.

We will ask you to listen to real words and non-words and make judgements about them. We may also ask you to complete some tests of language ability. The total time commitment may be up to four hours but will be split into two sessions.

Amount varies depending on the study

Yes
 

Krishnankutty Sathian
Josh Dorsi - at jdorsi@pennstatehealth.psu.edu
Neurology (HERSHEY)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00022919
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Inclusion Criteria:
Must be aged 18 or older
Must have English as your first language
Must have normal or corrected-to-normal vision
Must report normal hearing
May have a recent diagnosis of aphasia following a stroke

Exclusion Criteria:
Self-reported hearing difficulty
Bilingual persons may be excluded from some studies
Minors under the age of 18
Language & Linguistics
Not applicable
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Hershey, PA ,

Neurobehavioral mechanisms of social and non-social risky decision making.

The purpose of this study is to understand the neural and behavioral mechanisms subserving social and non-social risky decision making.

There will be one in-person lab visit where you will play a decision-making game, while having an fMRI scan.

$31.25

Yes
 

Nina Lauharatanahirun
Nina Lauharatanahirun - at nina.lauhara@psu.edu
Biomedical Engineering (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023716
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Inclusion Criteria:
18 years or older
Able to read and speak English
Normal to corrected vision in order to see a computer screen clearly
No history of head injury
No MRI contraindications

Exclusion Criteria:
Claustrophobia
History of head injury
Had an event where loss of consciousness > 10 minutes
Weighs more than 300 pounds
Does not read and speak English
Neurology
Not applicable
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State College, PA ,

Early Identification in Older Adults of Risks to Sleep Health, Movement, and Cognition Using Ecological Methods

This proposal is a prospective study in which we will collect both subjective and objective quantitative data from older adults residing in independent living retirement communities, microlongitudinally (~1wk). Comprehensive measures of sleep health, cognition, and movement will be collected at community residences. The first phase of this project will recruit local, State College area adults over 70 residing in independent living facilities (e.g., Foxdale Village and The Village at Penn State). A second phase of data collection will extend to community-based older adults in rural parts of Centre and nearby counties.With this prospective, microlongitudinal information we will evaluate the characteristics of sleep predictive of daytime cognitive and neurobehavioral function and use those conclusions to inform nonpharmacologic, preventative interventions for older adults.

After consent, there will be 6 study visits at either Penn State University Park campus or at the participant's personal residence. Study participation lasts about 1 week.Participants wear non-invasive ambulatory watch-like activity monitors throughout (both day and night) the week. Participants complete electronic surveys and cognitive tests 6 times daily, with additional surveys at study conclusion.Sleep and daytime brain and heart activity are recorded (without video) using non-invasive clinical-type wire sensors applied to the face, head, and chest. Wires are worn on the face, head, and chest throughout the first two study nights. Wires are worn on the head and chest throughout the first two study days. There is not a sleep intervention in this study. We are collecting data about the typical sleep health of older adults and its relation to cognitive health.

$350

Yes
 

Orfeu Buxton
Margeaux Gray - at ecosleep@psu.edu or 814-863-5800
Biobehavioral Health (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00011786
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Inclusion Criteria:
>=50 and <91 years of age
Resident of PA, Centre County region
Living without functional assistance
Able to walk unassisted for at least 5min

Exclusion Criteria:
Previous participants are not eligible
Evidence of cognitive impairment (will be tested)
Men's Health, Sleep Management, Women's Health
Not applicable
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State College, PA ,

Sex and race differences in exercise pressor reflex under blood flow restriction condition

The purpose of this voluntary research study is to test the effects of exercise on reduction in blood flow to exercising muscle.

You will be asked to participate in one visit to perform handgrip exercise and foot exercises with, and without a blood pressure cuff inflated on your arm and leg. Various physiological measurements will be recorded during this time including microneurography, blood pressure, heart rate, blood flow and muscle oxygenation.

You will receive $25 per hour for your participation in this research study

Yes
 

Jian Cui
Cheryl Blaha - at cblaha@pennstatehealth.psu.edu or 717-531-1605
Heart and Vascular Institute (HERSHEY)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023505
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Inclusion Criteria:
Males and Females 21-80 years of age
All races and ethnicities welcome
Are fluent in written and spoken English
Healthy status as defined by history and physical
blood pressure that is within a safe range (<150/100)

Exclusion Criteria:
less than 21 years of age or greater than 80 years of age
Pregnant or nursing woman
Current smoker
Any chronic diseases (heart, lung, neuromuscular disease or diabetes)
High blood pressure
Heart & Vascular
I'm interested
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Hershey, PA ,