The purpose of this study is to investigate whether fermenting pulse foods (e.g. beans, chickpeas, lentils, peas, etc.) changes their effects on the gut microbiome and inflammation. Participants will eat provided meals of either fermented or unfermented pulses, providing blood and fecal samples at the beginning of the study and after two weeks of eating meals containing each of the pulse types.

The study lasts 8 weeks. 2 weeks where you do not consume any of the test food (pulses such as chickpeas, lentils, peas or beans), 2 weeks of consuming the first type of the provided meals, 2 weeks without consuming any of the test foods, 2 weeks consuming the second type of provided meals. There will be five in person visits, one at the beginning to provide consent and then one at the end of each 2 week section. At three of these visits a fecal sample will be collected, blood will be drawn and a dietary survey completed.

300

To comprehensively examine the psychological effects of abstract lighting patterns on individuals' emotional states, cognitive performance, and overall well-being. Secondly, the study aims to explore the intriguing connection between music-color synesthesia and the perception of lighting conditions.

Participants will complete cognitive tests and subjective evaluations

The purpose of this study is to test how social decisions are affected by possible risk of infection. We aim to examine the neural and behavioral mechanisms underlying how choices in a risky social decision-making situation can be influenced by viewing images of infection threat (e.g., person with runny nose) vs. images of neutral scenes or other threatening scenes.

Participants will come to the research site for a one-time visit. They will complete brief questionnaires, followed by playing a social decision-making game while undergoing fMRI scanning.

$35.42

The effect of familiarity of an space on visual and lighting perceptions, and the effect of lighting conditions on risk taking and decision making will be investigated

Participants will wear sensors and complete survey that consists of decision making questions and subjective evaluations of architectural spaces.

In this study, we hope to better understand the neural mechanisms underlying risk for personality disorders in adolescent youth. Understanding who is at risk for personality disorders early in development is important in order to develop preventative interventions.

Youth participants and their parent will be required to attend one in-person visit at our lab in Hershey, PA where youth participants will complete two computer tasks while EEG data are collected. Youth participants will also complete questionnaires and a peer-interaction task with another peer their age. Parents will complete questionnaires and an interaction task with their child. Youth participants will complete remote surveys via a survey app for two weeks after the visit. This study includes 4 follow-up appointments (once every 6 months) which can be completed in-person or remotely via a Microsoft Teams meeting. These follow-up appointments will consist of a parent-child interaction task and surveys for parent and youth participants.

$300

The objectives of the study are to determine whether grip force is related to participants’ fear and whether touch feedback from a robot can effectively communicate risk in a simulated high stress environment. We hypothesize that grip force increases in stressful situations like walking through a haunted house. Like in a real haunted house, people often find comfort in holding hands with someone as they walk through. In this study, a participant walks through a virtual haunted house.

There will be one in person visit. Participant will wear VR equipment and chest heart rate monitor. They will hold a virtual robot's hand and walk through a VR haunted house environment until it is over. They will then answer a brief survey.

15

In this study, we're investigating how the COVID-19 pandemic has influenced the way people who face challenges in transportation—perhaps due to limited access or resources—get around. We're curious about any changes they made during the pandemic, like using different modes of transportation or adjusting their travel habits. Additionally, we're exploring whether these changes might stick around even after the pandemic. It's all about understanding the impact of the pandemic on the travel choices of those who already face transportation difficulties and what this might mean for the future.

There will be a questionnaire that should take approximately 15 minutes to complete.

The purpose of this study is to collect normative data related to orofacial (lip/tongue) somatosensation (touch sensation) in healthy adults across the adult lifespan. This data will be compared to a select clinical population, those with Parkinson's disease.

There will be one data collection session lasting approximately 90 minutes. Participants may be invited back for a second session approximately 4 weeks later to repeat the testing sessionDuring the sessions, participants will answer a series of questions about their eating and drinking preferences, they will be asked to provide a speech sample by repeating a series of syllables, words, and sentences, as well as providing a spontaneous speech sample.All participants will be asked to complete a series of sensory tests where small plastic objects are placed on their lip, tongue, and finger tip. Participants will be asked when they feel the pressure/texture and when they do not.

The purpose of this research study is to determine if a healthy diet containing 2 eggs/day has similar effects on risk factors for heart disease as a healthy diet containing 3 eggs/week.

This study runs for about 3 months. During this time, you will be provided with two diets in random order to consume for 28 days. These diets will meet your energy and nutrient needs and include 3 meals, 2 snacks and some beverages. During this time, we will ask you not to eat any foods outside of those provided by the study. You will have a 1-month break between the two diets. Testing will be conducted on two separate days at the beginning and end of each diet period (a total of 8 testing days). For these visits, you will need to fast for 12 hours prior and avoid alcohol for 48 hours prior. At these visits, we will take a blood draw, measure your body weight, and perform non-invasive tests to assess your vascular health.

400

The aim of this study is to examine the effect of wearing CROCS with or without a heel-strap on walking mechanics.

There will be one in-person visit to take place at Penn State Altoona. During this visit, lasting approximately two hours, participants will undergo a simple consent process and they will provide information about their physical activity and fitness history. Body measurements, such as height, weight, and leg length will be recorded during the visit. Participants in the study will complete a five-minute treadmill warm-up at a self-selected walking speed while wearing a pair of CROCS, Inc. clog-style shoes (provided). After the warm-up participants will complete a series of 15 walking trials consisting of three randomized conditions (barefoot, no heel-strap, heel-strap) on a level and firm walking surface. During these trials, the participant will wear lightweight sensors on the lower-body to track walking patterns. Images and videos will be acquired during the visit, but all distinguishing features will be blurred or omitted upon archiving.

This study will compare the use of CCT-102 with expectant management to promote uterine evacuation in first trimester non-progressing Delayed Pregnancy Loss (DPL). Eligible participants will be randomly assigned to active treatment or expectant management and will undergo ultrasound, physical examination, sample collection and complete daily diaries.for six days. Participants will be monitored up to 208 days until a negative urine hCG test is achieved.

There are 3 visits and a screening visit which may be combined with visit 1. A physical examination, ultrasound and blood draw will take place at screening and visit 2. Urine pregnancy tests will be taken at screening, visit 1, visit 2 and at home on days 14, 21 and 28 or until a negative result occurs. Electronic diaries will be logged days 1 through 7

595

The purpose of this study is to assess if a healthy diet containing cottonseed oil improves markers of heart and metabolic health compared to healthy diets containing other commonly consumed plant oils. Participants will be asked to consume three different healthy diets containing plant oils for 28 days each, with a minimum 1-month break between the three diets. Measurements of blood markers (sugar, insulin, cholesterol), blood pressure, and heart health, will be done at the start of the study and the end of each diet period.

In this study, you will be asked to consume three different diets for 28 days each. The diets will be provided and include 3 meals, 2 snacks and beverages daily. These diets will meet your energy and nutrient needs. You will be asked not to eat any foods outside of what is provided by the study. You will have a minimum 1-month break between the three diets. Testing will be conducted on two consecutive days at the start of the study, and the end of each of the three diet periods (a total of 8 testing days). For these visits, you will need to fast for 12 hours prior and avoid alcohol for 48 hours prior. At these visits, we will take a blood draw, measure your body weight, and perform non-invasive tests to assess your vascular health.

500

This research experimental study aims to investigate the impact of gender and language on stigma related to opioid use disorder (OUD) among college students. Participants, aged 18 and older, will be randomly assigned to read vignettes describing individuals with OUD, varying in gender and language use. After reading, participants will complete a brief survey assessing their perceptions of stigma associated with OUD. The study seeks to uncover how stigmatizing language and gender-specific societal expectations interact to shape attitudes, contributing to a better understanding of OUD stigma in the college-aged population.

Participants will engage in a structured series of activities. Initially, they will complete a demographics questionnaire, providing essential information such as age, gender, and college affiliation. Subsequently, participants will be presented with one of four vignettes designed to systematically manipulate language and gender variables related to OUD stigma. Following the vignette exposure, participants will respond to The Perceived Stigma of Substance Abuse Scale (PSSAS) as part of the survey.

The purpose of this study is to define how eye movements contribute to eye-hand coordination in individuals of the age group 18-50 (young adults) and 65-80 (older adults). Specifically, the aim of the study is to understand how slow eye movements affect arm and hand movements. All procedures to be used in our study will be non-invasive. The task during the study will be performed with a robotic handle that participants will grasp with their right hand. They will interact with visual stimuli by moving the robotic handle. The robotic environmentwill attempt to simulate real-world mechanical interactions, such as those experienced during catching a ball.

During this study, we will ask you to come to our laboratory located in 23 Recreation Building,Pennsylvania State University, on two days separated by a maximum of 48 hours. Both sessions will last approximately 90-120 minutes. During the first session, we will review the procedures with you and if you agree to participate, you will sign this form and then proceed to perform the study. You will perform about 20-25 blocks of hand movements. Each block will consist of 24-30 trials and each trial will last between 3-5 seconds.The second day will be identical to the first day but the order of trials within a block will be changed.

$10/hour

Determine if free radicals produced by electronic cigarettes or conventional cigarettes impact inflammation and oxidative stress responses in users.

Subjects will come to the Clinical Research Center at Hershey and if they are a nicotine user they will bring their device (cigarette or e-cigarette) with them. Healthy volunteers will answer the same questionnaires and provide the same samples but will not use any nicotine during their visit. They will provide blood, urine and exhaled breath condensate samples. They will be videotaped using their own devices and they will answer questionnaires. This is a one-time visit that will last around 2 hours.

50

This study is designed to better understand how people complete complicated tasks, and the best ways in which to measure their performance. If you agree to the study, you will be asked to fill out questionnaires on your thoughts, feelings, and behaviors; take a short interview on the same; and complete brain teasers and computerized tests of attention and learning.

There are several steps to determining whether you are a good fit for the study. If you agree to be in the study, then we will send you a link to complete online questionnaires (~10 min) on your thoughts, feelings, and behaviors. If you are a good fit, then we will schedule a laboratory visit in Moore Building at the University Park campus (maximum length of time = 3 hours). During that visit you will complete an interview and more questionnaires, brain teasers, and computerized tests of attention and learning. The visit will be video recorded for quality assurance.

$50

This study aims to learn about how university students interact with ChatGPT and how ChatGPT's support of autonomy, competence, and relatedness could either help or hinder students' ability to learn. We will interview students to understand how ChatGPT supports student learning and identify any challenges that may arise.

There will be a 60-minute interview.

$10

This study aims to build upon a previous study that established a different presentation of autism called the ISM presentation by using a large sample size to either confirm or dispute this presentation as an alternative to classical autism.

Participants will be required to complete a survey expected to take no longer than an hour.

The broad goal of this project is to provide both theoretical and algorithmic solutions for efficient adaptive federated learning, as well as build practical adaptive federated learning systems for real-world applications.

Each participant carrying or wearing a smart device will conduct six activities, including (a) Wiping the whiteboard; (b) Walking; (c) Moving a suitcase; (d) Rotating the chair; (e) Sitting; (f) Standing up and sitting down. We will collect nine signals from each smart device, including three axes of the accelerometer, three axes of the gyroscope, and three axes of the magnetometer.

$20

The purpose of this research study is to better understand how leg blood flow is regulated in healthy people and patients with Peripheral Arterial Disease (PAD). It is also being done to examine if a standard-of-care peripheral intervention procedure to improve blood flow to the leg in PAD patients will improve the oxygen delivery and blood flow response to exercise in their legs.

Healthy subjects will participate in 1 visit and perform handgrip and foot (plantar flexion) exercises while several non-invasive measurements are recorded.

You will receive $25 per hour for your participation in this research study

This study will examine the impact of age, sex, and racial/ethnic background on vascular function.

There will be three in-person visits: one screening, one experimental visit, and one visit to return equipment (if applicable). Blood will be drawn at the screening and experimental visit. Participants will undergo tests for cardiovascular measures.

$100

This research study is being done to understand how different techniques for practicing sentences are affected by healthy aging. This will help us create better language therapy for people with aphasia.

There will be one visit. It can be in-person or over Zoom. We will ask you to fill out a questionnaire about yourself, complete a brief cognitive assessment, and complete a sentence production task. This visit should only last about 90 minutes.

up to $15

The purpose of this study is to understand parents' experiences of emotion regulation in parenting and coparenting contexts and how individual differences in parents' emotion regulation are associated with well-being and relationship functioning.

Coparents will be asked to fill out questionnaires and engage in interviews with the researchers during three online sessions across the transition to parenthood.

110

The purpose of this study is to evaluate the nicotine delivery, toxicant exposure, and subjective effects associated with the use of heat-not burn tobacco products, compared with electronic cigarettes.

Participants will attend 2 clinic visits at the Penn State Milton S. Hershey Medical Center lasting approximately 1 ½ hours each. Participants will be asked to refrain from using any tobacco or nicotine products for at least 14 hours prior to each visit. During the visit participants will try the new tobacco products in the study center while blood samples are collected through an IV catheter placed in the arm.

120

This research is being done to better understand how certain parts of the brain may react differently in people who have a particular eating disorder, anorexia nervosa, which may help us understand why they respond to food in the way they do. This may help us design more effective treatments for people with anorexia nervosa.

You will complete a package of surveys for personality, psychopathology, an evaluation of taste functions, and an MRI/fMRI examination.

Up to a total of $100.

This study investigates the influence of different rest design of restaurant on participants’ food consumption behavior. More specifically, visually pleasant versus visually unpleasant design elements are included in two cafe settings to study their influence on participant liking, and emotion response. To accomplish this, we will conduct an experiment where participants will be eating a meal while immersed in a virtual café interior with two different designs using a VR headset. Their food intake will be measured.

Participants will visit the lab for 3 sessions to eat a meal each time while wearing an immersive virtual reality headset.

$30

The aim is to conduct a pilot study to assess the feasibility, acceptability and potential effectiveness of culinary focused nutrition education to promote increased adherence to the Dietary Guidelines for Americans compared to standard low-intensity care.

You will be asked to attend two fasting clinic visits. At these visits paperwork will be completed, measures of weight, height, waist circumference, and vascular health will be taken. A blood draw will also be taken. If you are randomized to the culinary focused nutrition education group, you will be asked to attend weekly 1-hour face-to-face group education sessions during the first month of the study. For months 2 and 3 face-to-face sessions will be held bi-weekly for 1 hour. You will also receive emails containing videos and other resources. If you are in the standard nutrition education group, you will receive nutrition education via written study material and a phone application (app) and you will not have to attend education visits.

250

In this study, we are trying to determine whether Vitamin B6 will help improve the exercise-induced cardiovascular response in healthy participants following a procedure by restricting and recovering the blood flow to the leg.

There will be 6 in-person visits over a month long supplementation of Vitamin B6. Three visits will include a blood draw. Half of the visits will include walking a treadmill and 3 will involve foot exercise (plantar flexion)

You will receive $25/hour for in-person visits and $50 for completing the B6 supplementation

Average global temperatures and the number of heat waves have increased recently. Humans sweat and increase blood flow to the skin to cool their body when they get hot. Older adults (>65 yrs) do not do this as well as younger adults. This makes them at risk for heat-related illnesses. It is important to learn about cooling strategies that will lower body temperature for older adults in the heat. In this study, we will determine if placing your hands and forearms in cold water and/or supplementation with folic acid are effective cooling strategies for older adults resting in the heat.

There will be 4 in-person visits in a hot and humid environment, there will be folic acid supplementation and placebo for 6 weeks each

300