Search Results Within Category "Heart & Vascular"
Thermoregulatory responses to heat stress in adults with major depressive disorder with and without antidepressant treatment.
The purpose of this study is to determine if, compared to non-depressed adults, differences exist in skin blood flow and sweating responses to passive heat stress in adults with clinically diagnosed depression, those with depression who are prescribed and taking SSRIs (Selective Serotonin reuptake inhibitors) and those with depression who are prescribed and taking SNRIs (Serotonin-Norepinephrine reuptake inhibitors).
For this study, you will be asked to come into the lab for a screening visit, a maximal exercise test visit, and one experimental visits. *Before the experimental visit, you will be asked to swallow a temperature-sensing capsule to measure your internal body temperature 1-2 hours prior to arriving at the lab. During the passive heat stress experiment, you will wear a suit lined with tubing through which hot water will run, causing your body to warm up. We measure your sweat and skin blood flow responses.
50
Depression treatment with SSRIs
Depression treatment with SNRIs
Adults aged 18-40
Use of psychoactive or psychopharmacological drugs other than SSRI and SNRIs within one year of participating.
Non-Hispanic Black Individuals and Vascular Function
This study will examine the impact of age, sex, and racial/ethnic background on vascular function.
There will be three (3) in-person visits: one screening, one experimental visit, and one visit to return equipment. Equipment includes a 24-hour Ambulatory Blood Pressure monitor and an 8-day accelerometer (physical activity tracker). Blood will be drawn at the screening and experimental visit. Participants will undergo tests for cardiovascular measures during the experimental visit.
$100
Male or Female
Identify as Non-Hispanic Black or Non-Hispanic White
Tobacco consumption (e.g., smoking) or Recreational drug use (e.g., marijuana)
Pregnant and/or breastfeeding
Taking blood pressure medication
Diagnosed with metabolic and/or cardiovascular disease(s)
Effects of atherosclerosis on the autonomic responses to systemic nitric oxide
This research looks at whether atherosclerosis, which is the buildup of fatty deposits in the arteries, affects how nitric oxide works to control blood pressure. Nitric oxide is a substance in the body that helps blood vessels relax and widen. By studying how these two factors interact, we hope to better understand them, which could lead to improved treatments for patients in the future. However, this study does not provide treatment for patients with heart or blood vessel diseases.
You will be asked to participate in one visit and to receive a medication called sublingual nitroglycerin. Various physiological measurements will be recorded during this time including microneurography, blood pressure, heart rate and blood flow.
You will receive $25 per hour for your participation in this research study
Any race or ethnicity
Men and women age 21- 80 years
Capable of speaking English
blood pressure is <160/100 mmHg
Pregnant or nursing women
Incapable of speaking English
Decisional impairment
Patients with diabetes