Search Results Within Category "Women's Health"
The Ethics of the Influence of Beauty-Focused Social Media Content on Cosmetic Procedure Intentions and Utilization Among Women Aged 21-25
This mixed-methods study examines the relationship between engagement with beauty-focused social media content created by young female influencers and intentions to pursue cosmetic procedures among women aged 21-25. The research employs both quantitative survey methods and qualitative interviews to understand this relationship and its ethical implications.
1 online survey (5-10 min) Some participants may be asked to partake in a 15 min qualitative interview
social media use of at least 3 hrs/week
ability to provide informed consent
under 21
diagnosed body dysmorphia
Neurocognitive Dynamics of Perimenopause: Patterns, Predictors and Mechanisms of Healthy Aging
The purpose of this study is to examine cognitive function during perimenopause and explore how these changes may be related to sex hormone levels and other psychological effects. The present study aims to address this gap by examining associations between estrogen and progesterone, as well as fluctuations in these hormone levels, in relation to cognition, measured comprehensively across self-report, behavioral measures, and neural assessments. By examining hormonal effects on cognition, the proposed study aims to inform strategies for early detection of cognitive vulnerability, promote resilience, and ultimately improve cognitive health outcomes for women across the lifespan.
Participants will be required to attend two in-person visits at our lab in Hershey, PA. At the first in-person visit, participants will complete three behavioral tasks and two computer tasks while EEG data is recorded. Participants will also complete questionnaires and give a saliva sample. Additionally, for four-weeks after this visit, participants will complete remote cognitive games and surveys via a link sent through text message and will collect saliva samples at home three times a week during this time. After four-weeks, participants will return for their second in-person visit where they will repeat the three behavioral tasks, a few questionnaires, and give another saliva sample.
$200
Fluent in English
Have had at least one menstrual period in the past 3 months
Have an intact uterus and at least one ovary
Have access to a smartphone
Not fluent in English
Women experiencing amenorrhea
Women who have had a hysterectomy
Platform Wars: Evaluating postural and strength adaptations with Wii Fit Balance vs. Whole-body vibration in college students.
This study will aim to see if there is a difference in strength and balance changes among college students when comparing the Wii Fit Balance and whole-body vibration training.
The study duration will be six-weeks, in which study participants will be involved in either a gaming training group or a vibration platform training group. Participants will complete a baseline session and post-training assessment, each lasting two hours. During both of these visits measures of balance, strength, and walking ability will be acquired. In the six weeks of the study,18 individual vibration or gaming training sessions will be completed. The respective training sessions will take place three times a week for 6 weeks and will last 10-minutes each.
$20.00
Male and female between the ages of 18 and 25.
Known history of musculoskeletal, neurological, cardiovascular, or pulmonary impairment that may affect ability to perform the testing procedures.
Use of a pacemaker.
Major general medical disorders, such as recent surgeries, implants in trained body parts (i.e., artificial joints), acute hernias, discopathies (i.e., slipped disks), rheumatoid arthritis, epilepsy, and/or acute thrombosis.
Using sedatives of any type upon enrollment to the study.
Menopause Stage and Depression Symptomatology
This study aims to examine differences in physiological variables (inflammation and heart rate variability) at different menopausal stages and whether these differences influence depression symptomatology. There will be one 3.5-4 hour in person study visit that includes completion of questionnaires, cognitive tests, electrocardiogram (ECG) recordings, and one blood draw.
There will be one 3.5-4 hour in person study visit that includes completion of questionnaires, cognitive tests, electrocardiogram (ECG) recordings, and one blood draw. If you are in the early perimenopausal/late reproductive group and still having menstrual periods, you will be asked to record menstrual bleeding on a menstrual calendar for 3 cycles.
75
assigned female at birth
English fluent
less then 2 years past the final menstrual period if postmenopausal
if on antidepressants, on a stable dose for 8 weeks
taking hormone medications in past 3 months
on strong anti-inflammatory medications
history of cardiovascular (other than hypertension) or neurological disease
Diagnosis of Bipolar or Psychotic Disorder
A Clinical Investigation of the Adjustable Continence Therapy (ACT) for Female Stress Urinary Incontinence Due to Intrinsic Sphincter Deficiency
The purpose of this study is to find out if an implant of ACT is safe and effective in reducing urinary incontinence. The study will involve about 132 women that have urinary incontinence. This system is investigational. After placement of the devices, participants will be followed for 12 months on a regular visit schedule. Annual visits may continue for up to 5 year. ACT® is an implantable device for treating stress urinary incontinence. One end of the device is a balloon that is attached by a tube to a port at the other end of the device.
Participants will attend a screening visit, the implantation visit, post-op assessment, 6 week, 3 month, 6 month, 12 month, and annual follow up visits for necessary device adjustments.
600
Failed at least 6 months of previous treatment for stress urinary incontinence
Currently undersoing radiation therapy
Pregnant/lactating women
A Prevention Strategy For The Indication Of Prune Consumption In Perimenopausal Females: Can Prunes Attenuate Bone Loss?
This project will be an 18-month dietary intervention of prune consumption during the late perimenopausal period of the menopause transition investigating if prune intake can slow down the rapid period of bone loss (bone mineral density) that occurs in the late transmenopause. The study will also investigate the effects of prune intake on inflammation, gut permeability, gut microbiome, and bone strength and geometry. Women transitioning into menopause will be randomized to either a group that will consume 6 prunes/day or to a no-prune group that will avoid prunes for the entire duration of the 18-month intervention. Both groups will consume calcium and vitamin D supplements daily. Study procedures will include collection of blood, urine, and stool samples, bone and body composition scans, completion of health-related questionnaires, exercise records, and daily compliance logs.
Participants will be asked to consume calcium and vitamin D supplements daily for 18 months and will be randomized into either a group that will be asked to consume 6 prunes daily for 18 months, or a control group that will be asked to avoid prunes and similar fruits (for example, blueberries, blackberries, pomegranates) for 18 months. There will be 10 in-person visits and 13 virtual visits (Zoom calls). In-person visits include questionnaires, blood draws, and bone and body composition scans. The study also involves urine and stool sampling.
$300
Overall good health
Non-smoking
Ambulatory
At least one episode of no menses of ≥60 days within the past 12 months but no more than 18 months since final menstrual period
Taking hormonal medication or hormonal contraception
Taking medication for osteoporosis
Untreated hypo- or hyperthyroidism
Hyper- or hypoparathyroidism
Tilt Testing in Endometriosis
Endometriosis is a common condition that can sometimes affect the nerves and may also impact heart and blood‑vessel health. In this study, we will use routine medical tests that show how the nervous system and cardiovascular system work together. Women with and without endometriosis will go through standard tilt testing - laying still on a table while the head of the table is tilted upward. Blood pressure and heart rate are measured. Participants then wear a blood pressure monitor for 24 hours.
Participants will go through standard tilt testing (laying down on a table that is tilted head up) and 24-hour blood pressure monitoring (wearing a portable blood pressure monitor while going about their day for one day).
100
At least one intact ovary
Aged 18-49
With and without endometriosis
Diagnosed cardiovascular, neurological, or endocrine disease
Current or recent nicotine use
Hypertension
A Phase 2, Double-Blind, Placebo-Controlled Study to Investigate the Safety and Efficacy of Mibavademab in Adult Women with Functional Hypothalamic Amenorrhea
The study is researching an experimental drug called mibavademab. The study is focused on patients with a condition called Functional Hypothalamic Amenorrhea (FHA). FHA is a condition where a woman stops menstruating because the brain is not sending the correct hormonal signals to the ovaries, which then are not able to cycle and ovulate properly. The aim of the study is to see how well the study drug helps the body make the hormones necessary for ovulation and reproduction, and to assess its safety.
Subjects will have 18 in person visits, 1 EKG, 8 blood draws, pregnancy tests, 2 Dexa scans, transvaginal ultrasound, menstrual monitoring, optional blood sample for DNA isolation. Participation will last approximately 11 months.
BMI between 18.5 (18.5 included) and <25 kg/m2 at screening. OR BMI 25 (included) to < 30 kg/m2 with a serum leptin level < 8.0 ng/mL at screening.
Diagnosis of Functional Hypothalamic Amenorrhea as defined by the Endo Society Practice Guidelines
No menstrual bleeding episode within 3 months prior to Day 1
Willing and able to comply with clinic visits and study-related procedures.
Pregnant, breastfeeding, or lactating
Blood estradiol ≥ 50 pg/ml or blood progesterone ≥ 1ng/ml at screening
Uterine (e.g. absence of uterus, prior endometrial ablation, endometriosis outflow tract disorders) or ovarian (e.g. absence of an ovary, presence of polycystic ovaries) conditions that impact assessment of menses or of the HPO axis
Use of medications affecting bone metabolism and/or HPO axis (e.g. bisphosphonates, teriparatide, denosumab, estrogen, progesterone, anabolic steroids, GnRH agonists or antagonists, gonadotropins or analogues
AI Chatbot Use for Personal and Emotional Support: Patterns, Perceptions, and Help-Seeking Behavior
This study examines how individuals use general-purpose AI chatbots (e.g., ChatGPT, Gemini, Claude) when responding to personal, emotional, or difficult experiences, including experiences of victimization. Participants complete an anonymous online survey taking approximately 15–20 minutes covering patterns of chatbot use, emotional responses to these interactions, and help-seeking behavior. The study is open to all adults 18 and older. Participants may optionally enter a raffle for one of ten $25 Amazon e-gift cards.
Completing a brief, anonymous online survey that takes approximately 15–20 minutes.
Be able to read and understand English.
Have access to the internet and a device capable of completing an online survey.
Provide implied consent to participate by continuing past the consent screen and completing the survey.
Do not provide informed consent to participate.
Are unable to read or understand English.
Evaluating the Efficacy of a Comic-Based Activity Booklet for Reducing Mammography Anxiety
The purpose of this study is to evaluate whether a comic-based educational booklet can reduce anxiety and support coping during a simulated diagnostic mammography callback experience. We aim to assess participants’ emotional responses to the simulated callback process, evaluate whether the booklet improves confidence in managing uncertainty during the waiting period, and gather feedback on the booklet’s clarity, usefulness, and acceptability.
What participation involves: Participants complete two brief surveys remotely—one before and one 1–2 weeks after attending an in-person study session at a date and time convenient for you. The in-person session will take place in a comfortable, non-clinical area at Penn State and is completely independent of your imaging appointment. During the in-person session, you will: - Read and sign an informed consent form. - Complete three brief surveys. - Watch a simulated mammography video. - Read through and use a brief (and fun) activity booklet designed to support patients during the waiting period. - Participate in a brief focus group with a member of the research team and several other participants. Your total participation time, including the remote surveys and in-person session, is approximately 75 minutes.
Participants will receive a $25 Greenphire ClinCard.
Individuals who have had a mammogram callback after routine screening within the last 2 years.
Able to read and understand English, as the booklet and questionnaires will be provided in English.
Non-English speaking (due to language limitations of materials used in the study).
Individuals unable to demonstrate an understanding of the study procedures or who decline to provide informed consent.
Individuals who have previously participated in this study.