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Search Results within category "Diabetes & Hormones"

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Suggestions within category "Diabetes & Hormones"


13 Study Matches

A Longitudinal Study To Identify Early Non-invasive Ocular Markers of Diabetic Complications

This is a human subject study looking at the complications arising in newly diagnosed diabetic patients using non-invasive measures, optical coherence tomography (OCT) and corneal confocal microscope (CCM), indicative of peripheral neuropathy and diabetic retinopathy. Through the use of these devices we would like to determine the onset of corneal nerve fiber alterations and retinal thinning in newly diagnosed diabetics. This information could help investigators find early and reversible biomarkers to target for therapeutic options.
Ellen Stoute at estoute@pennstatehealth.psu.edu or 717-531-4696
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
Corrected visual acuity of 20/25 or better
Patients with diabetes must be newly diagnosed, withing the last 5 years
Diabetics must have initial HbA1c of greater than 6.5 or a fasting glucose of 126 or higher
Exclusion Criteria:
History of vitreous or retinal surgery
Lasix surgery
Previous ocular trauma
History of diabetic complications
Cataract surgery within 3 months of enrollment
Vision & Eyes, Diabetes & Hormones
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Location
Hershey, PA

A Pilot Study to Dynamic Modeling of the Effects of Physical Activity on Blood Glucose Levels in Type 1 Diabetes

This research study will help us to better understand how your blood sugar level changes when you do physical activity, especially when you do exercise. Our research team will collect data to help us understand how what you eat, your insulin dose, and what physical activity you do would affect your blood glucose level. You have to have type 1 diabetes and use an insulin pump to manage diabetes. In addition, we will have you wear a continuous glucose monitor, record the food you eat using MyFitnessPal, and wear activity monitors to track what physical activity you do over the 12- or 16-day study period. You would come to the Clinical Research Center at Penn State for your initial visit and to exercise either two times during the 12-day study period or three times during the 16-day study period. You will be compensated up to $140 for completing the entire study. If you have Type 1 Diabetes and would like to participate in this research you can contact our team at 814-863-7126 and we'll give you more details.
Christa Oelhaf at cmj108@psu.edu or 814-863-7126
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
Young adult and adult individuals with Insulin Pump treated Type 1 Diabetes; ages 18-45 years living in and around Central Pennsylvania.
Well established (>6 months) in using an insulin pump to manage diabetes.
A user of Continuous Glucose Monitor (CGM) to measure interstitial glucose levels, and willingness to continue during the study.
Willingness to avoid moderate or strenuous exercise during the study, other than exercise that is part of the study.
Self reported most recent Hgb A1C < 10%.
Exclusion Criteria:
Contra-indications to engaging in exercise (i.e., health care provider has indicated no/limited activity due to a health condition – as disclosed by the subject)
Uncontrolled hypertension i.e. BP >140/90 mm Hg (ADA criterion) at the assessment visit, measured by the CRC protocol; repeat screening after potential medication adjustment by subjects health care provider is permissible.
Diagnosed significant coronary artery disease, unless written clearance by the subject’s health care provider is given.
Hypoglycemia unawareness
Currently pregnant, breastfeeding or trying to become pregnant during the likely study time frame
Diabetes & Hormones
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Location
State College, PA

Site For Trial to Access Chelation Therapy TACT2

Site For Trial to Access Chelation Therapy TACT2
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT02733185
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Inclusion Criteria:
History of diabetes
History of myocardial infarction
Equal to or greater than 50 years of age
Exclusion Criteria:
Myocardial infarction within the past 6 weeks
Heart failure hospitalization within the past 6 months
Cigarette smoking within the past 3 months
Heart & Vascular, Diabetes & Hormones
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Hershey, PA

Site For TrialNet

Site For TrialNet
Patricia Carper at pcarper@pennstatehershey.psu.edu or 717-531-5656
All
All
This study is also accepting healthy volunteers
NCT00097292
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Inclusion Criteria:
aged 1-45 years and a sibling, offspring, or parent of an individual with type 1 diabetes
aged 1-20 years and a niece, nephew, aunt, uncle, grandchild, cousin, or half sibling of an individual with Type 1 diabetes
willing to have blood drawn
Exclusion Criteria:
Have previous or current use of medications for the control of hyperglycemia
Currently use immunosuppressive or immunomodulatory therapies
Has diabetes
Diabetes & Hormones
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Hershey, PA

The Effect of Evening Almond Butter Consumption on Fasting Blood Glucose

The aim of this study is to determine if giving an individual with type 2 diabetes a serving of natural almond butter before bed improves fasting blood glucose. We will recruit individuals with type 2 diabetes for this study and measure their blood glucose using a continuous glucose monitor.
Emily Johnston at exj22@psu.edu
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03826472
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Inclusion Criteria:
18-75 years of age
Diagnosis of type 2 diabetes
Without allergy to tree nuts
On stable dose of medication (no dose change for 6 months)
Willing and able to adhere to study protocol
Exclusion Criteria:
Individuals with type 1 diabetes, cardiovascular disease, kidney disease, liver disease, cancer or inflammatory conditions (e.g. GI disorders, rheumatoid arthritis)
Pregnant or breastfeeding
Taking insulin or sulfonylureas
Tree nut allergy
Allergy to Dexcom CGM adhesive
Food & Nutrition, Diabetes & Hormones
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State College, PA

Angiotensin-(1-7) and Energy Expenditure in Human Obesity

We will investigate the effects of the hormone angiotensin-(1-7) on energy expenditure in patients with obesity.
Aimee Cauffman at acauffman@pennstatehealth.psu.edu or 717-531-1617
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03777215
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Inclusion Criteria:
Men and women of all races
Age 18-60 years
Body mass index between 30-40 kg/m2
Capable of giving informed consent
Exclusion Criteria:
Age less than 18 years or greater than 60 years
Pregnant, nursing, or post-menopausal women
Current smokers
Type I or type II diabetes
History of major cardiovascular or cerebrovascular disease, immune diseases, impaired kidney or liver function
Heart & Vascular, Diabetes & Hormones
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Hershey, PA

Decreasing Stress in Type 2 Diabetes: A Randomized Controlled Trial (DE-STRESS T2D)

The purpose of this study is to find out how two different stress reduction programs affect blood sugar levels in people with type 2 diabetes. Participants will attend eighteen study sessions where they will take part in one or more of the following activities: breathing exercises, meditation, stretching exercises or health education activities. Participants will undergo questionnaires, blood tests, and a brief physical exam at baseline, eight weeks, six months, and one year. Compensation is provided.
Ellen Stoute at estoute@pennstatehealth.psu.edu or 717-531-8395
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT04016415
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Inclusion Criteria:
Age 18 years or older
Type 2 diabetes diagnosed for one year or more
Hemoglobin A1c 8% or greater
Have a smartphone
Able to attend 14 study treatment sessions
Exclusion Criteria:
Current suicidality, history of significant psychopathology such as bipolar disorder or psychosis
History of an inpatient admission for psychiatric disorder within the past two years
Active alcohol or drug abuse
Inability to read, write or speak English
Current enrollment in a stress reduction program, or in any other investigative study
Mental & Behavioral Health, Diabetes & Hormones
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Hershey, PA

The perception and experiences of newly diagnosed type 2 diabetes patients (T2D) on the impact of patient-provider communication on subsequent decision to engage in diabetes self-management education (DSME).

This study seeks to explore the perception and experiences of newly diagnosed type 2 diabetes patients about how their interaction with their provider at diagnosis led to their uptake of diabetes education.
Michelle Boakye at mdb521@psu.edu or 814-699-1783
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
Age 18 or older
Any gender
Newly diagnosed type 2 diabetes patient within the past 12 months
Have attended at least one diabetes education after diagnosis
Able to provide consent in English
Exclusion Criteria:
Patients who are below 18 years
Patients who have a different type of diabetes either than type 2
Patients diagnosed with Type 2 diabetes more than 12 months
Newly diagnosed diabetes patients who have not attended diabetes self-management education
Diabetes & Hormones
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Dining with Diabetes in Pennsylvania

Penn State Extension's Dining with Diabetes program is an evidence-based community education program for people with or at risk for type 2 diabetes. The program teaches participants how to prevent or manage their disease by providing practical knowledge and strategies to make the necessary lifestyle changes that will lead to healthier living and reduction in the risk of complications. The overall goals and objectives of the program are as follows: Increasing knowledge of healthy food choices for families with or at risk for diabetes Promoting behavior changes by offering demonstrations and tasting of healthy food. Increasing knowledge of essential medical tests associated with diabetes management. Promoting physical activity as a component of diabetes control. Encouraging self-management and self-efficacy skill. Connecting participants to their healthcare providers for long-term follow-up. The program is designed to meet 4 consecutive weeks and then a 3 month follow-up. Classes consist of a nutrition lesson, physical activity, cooking demonstration and food tasting.
Debra Griffie at dab210@psu.edu or 610-489-4315
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT04080960
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Inclusion Criteria:
Individulas with type 2 diabetes
individuals with pre-diabetes
individuals at risk of developing type 2 diabetes
healthy family members/caretakers
healthy volunteers
Exclusion Criteria:
under the age of 18
Diabetes & Hormones
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Study Locations

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Altoona, PA
DuBois, PA
Erie, PA
Greater Pittsburgh Area, PA
Hazleton, PA
Reading, PA
State College, PA
Wilkes-Barre/Scranton Area, PA

Raising a Child with T1D and Autism: Qualitative Thematic Analysis

We have utilized a previously completed forum and blog analysis conducted as STUDY00007977 to begin to identify to successes and challenges families raising a child with both T1D and autism experience. This study seeks to expand our knowledge through conducting interviews with families recruited both online and through the clinic. By using an Interview Guide created with our themes identified thus far, we will have a chance to expand on these themes through interviews, as well as hear from families that may not use the online community. We will recruit and interview families through the diabetes online community and through Penn State Hershey--6-8 of these families will have a child with optimal glycemic control and 6-8 of these families will have a child with suboptimal glycemic control. In addition to refining themes, this effort will help us assess the reliability, credibility, and validity of what was found via forum and blog analysis.
Jessica Wright at jwright3@pennstatehealth.psu.edu
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
Able to read, write and communicate effectively in English
Caregiver (parent, grandparent, adult sibling, guardian) to a child age 5-18 years with both T1D and Autism
Telephone and internet access
Willing to consent and complete study requirements
Exclusion Criteria:
Unable to read, write and communicate effectively in English
Not a caregiver (parent, grandparent, adult sibling, guardian) to a child age 5-18 years with both T1D and Autism
No access to phone or internet
Unwilling to consent or complete study requirements
Children's Health, Mental & Behavioral Health, Diabetes & Hormones
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Micromanagement strategies in pump users with type 1 diabetes: What happens in day-to-day insulin use?

Because we know relatively little about the day-to-day process of insulin therapy in type 1 diabetes, we will systematically study insulin pumpers' experiences with daily micro-management. Many studies of insulin therapy implementation simply assess the degree to which people with diabetes report following the recommendations of their healthcare providers, or the frequency with which people with diabetes skip an insulin dose or give themselves less insulin than prescribed. We will assess the process through which people on insulin pumps self-manage their insulin therapy and the aspects of living that affect glycemic control. We will have participants report their daily glucose values, different treatment decisions that they have made, and overall management of their daily glucose. The success of diabetes self-management is dependent on the way these decisions are made and implemented. At the conclusion of this study, we will have developed a new conceptualization, or theory, of insulin treatment in type 1 diabetes that can be used in educational interventions to improve both self-management of blood glucose (SMBG) and A1c outcomes.
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
Type 1 diabetes (self-reported)
Insulin pump for one year or more
Age =>25
Participant interested in diabetes research studies
Able to communicate in English
Exclusion Criteria:
No access to technology (i.e. computer, tablet, smartphone)
Diabetes & Hormones
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Pilot Study to Assess Medication Adherence, Health Literacy, and Technological Literacy among African Americans and Latinos with Hypertension

This pilot study aims explore the health literacy and medication adherence found among African Americans and Latinos with hypertension receiving care at Hamilton Health Center in Harrisburg PA. We also aim to determine the feasibility of the iPad or smartphone as a tool for accessing health related information among African American and Latino patients with hypertension receiving care at clinics at Hamilton Health Center in Harrisburg PA. The expected outcomes of this project are to obtain a better understand of the literacy levels and adherence behaviors of African Americans and Latinos in Harrisburg, Pennsylvania. The findings from this study will provide valuable insights into the health management behaviors of this community and determine if there is a need to develop a mobile health application for the management of hypertension.
Yendelela Cuffee at ycuffee@phs.psu.edu or 717-531-2044
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Diagnosed with high blood pressure
Prescribed medication for high blood pressure
African American/Black (Hispanic or Non-Hispanic) or White (Hispanic)
21 years and older
Able to speak and read English
Exclusion Criteria:
Unable to provide consent to participate in the study
Heart & Vascular, Diabetes & Hormones
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Location
Hershey, PA

Examining views associated with physical exercise and its connection to diet, social connectivity, and stress reduction: Focus Groups

The primary objective of this study is to examine, via focus groups, the perceptions that are held by potentially-eligible subjects in the PSH DPP program in regard to the importance of physical exercise, particularly within the context of diet, social connectivity, and stress reduction. These perspectives will then be used to help develop, test, and refine additional motivational text messages that can be used in a text messaging intervention.
Selena Ortiz at suo13@psu.edu or 814-863-8041
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Be at least 18 years old and under age 65
Body Mass Index ≥25 kg/m2 (≥23 kg/m2 if Asian)
Have no previous diagnosis of type 1 or type 2 diabetes
Fluent in English
Exclusion Criteria:
Under 18 years old and over age 65
Body Mass Index <25 kg/m2 (<23 kg/m2if Asian)
Previous diagnosis of type 1 or type 2 diabetes
Not fluent in English
Prevention, Education, Diabetes & Hormones
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Study Locations

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Location
State College, PA