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Suggestions within category "Diabetes & Hormones"


Study matches: 7

Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.


Natural History Study of the Development of Type 1 Diabetes

Natural History Study of the Development of Type 1 Diabetes
Patricia Carper at pcarper@pennstatehealth.psu.edu or 717-531-5656
All
Not specified
This study is also accepting healthy volunteers
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Inclusion Criteria:
aged 1-45 years and a sibling, offspring, or parent of an individual with type 1 diabetes
aged 1-20 years and a niece, nephew, aunt, uncle, grandchild, cousin, or half sibling of an individual with Type 1 diabetes
willing to have blood drawn
Exclusion Criteria:
Have previous or current use of medications for the control of hyperglycemia
Currently use immunosuppressive or immunomodulatory therapies
Has diabetes
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NCT00097292
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Location
Hershey, PA

A randomized, double-blind, placebo-controlled, parallel-group, multicenter, event-driven Phase III study to investigate the efficacy and safety of finerenone on the reduction of cardiovascular morbidity and mortality in subjects with type 2 diabetes mellitus and the clinical diagnosis of diabetic kidney disease in addition to standard of care.

The purpose of this study is to evaluate whether finerenone is effective and safe in treating patients with type 2 diabetes mellitus and Diabetic Kidney Disease (DKD) in addition to regular therapy.
Kim Hitz at khitz1@pennstatehealth.psu.edu or 717-531-4924
All
18 year(s) or older
This study is NOT accepting healthy volunteers
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Inclusion Criteria:
type 2 diabetes
clinical diagnosis of diabetic kidney disease
treatment with ACE or ARB
Exclusion Criteria:
HbA1c > 12%
uncontrolled hypertension
dialysis
current or scheduled kidney transplant
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NCT02545049
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Hershey, PA

A Longitudinal Study To Identify Early Non-invasive Ocular Markers of Diabetic Complications

This is a human subject study looking at the complications arising in newly diagnosed diabetic patients using non-invasive measures, optical coherence tomography (OCT) and corneal confocal microscope (CCM), indicative of peripheral neuropathy and diabetic retinopathy. Through the use of these devices we would like to determine the onset of corneal nerve fiber alterations and retinal thinning in newly diagnosed diabetics. This information could help investigators find early and reversible biomarkers to target for therapeutic options.
Ellen Stoute at estoute@pennstatehealth.psu.edu or 717-531-4696
All
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Corrected visual acuity of 20/25 or better
Patients with diabetes must be newly diagnosed, withing the last 5 years
Diabetics must have initial HbA1c of greater than 6.5 or a fasting glucose of 126 or higher
Healthy controls must have HbA1c less than 6.5 or fasting blood glucose of 100mg/dl or less
Exclusion Criteria:
History of vitreous or retinal surgery
Lasix surgery
Previous ocular trauma
History of diabetic complications
Cataract surgery within 3 months of enrollment
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N/A
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Location
Hershey, PA

Complex interactions of behavior, genes, and environment in the multi-system characterization of the effects of sleep loss on health, cardio-metabolic disease risk, cognition, and the epigenome

The purpose of this study is to see what effects sleep restriction (sleeping less than needed each night for many nights in a row) has on metabolism, cardiovascular regulation, cognitive function, and epigenomic changes in various tissues. This is an 11-day inpatient study. All of the 11 days and nights of the study will be spent in your study room in the Clinical Research Center at Penn State where you will live for the entire 11 days and nights without going home. During different days of the study you will be participating in several study procedures. These include: • Having your sleep patterns recorded every night • Taking performance and memory tests at regular intervals on a tablet computer everyday • Taking tests during an fMRI on three different occasions • Having blood drawn while you stay sitting in bed for up to four hours at a stretch while we test how your body processes sugar, or food on six different occasions • Having a small sample of fat (adipose tissue) removed on 2 different occasions We will determine your eligibility to be in the study during a screening process that consists of 4 screening bisits. Each visit will take up to several hours to complete and the entire screening process will take about 3 weeks. Completion of all screening visits: $50 Daily rate while living in hospital during 11-day study: $150/day (total $1,650) Incentive bonus for completing entire 11-day laboratory study: $550 Payment upon full completion: $2,250
Nicole Nahmod at SleepingBrain@psu.edu or 814-867-5977
Male
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Male ages 20-35
Non-smoker
Right-handed
Physically and mentally healthy
Willing to comply with screening and study procedures
Exclusion Criteria:
History of night work or recent travel across >2 time zone
Drug or alcohol dependency; History of certain medications and/or supplements
Certain food allergies or dietary restrictions
Acute, chronic, or debilitating medical condition or illness
History of psychiatric illness or disorder, including claustrophobia
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N/A
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Study Locations

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Location
State College, PA

A randomized, double-blind, placebo-controlled, parallel-group, multicenter, event-driven phase III study to investigate the efficacy and safety of finerenone, in addition to standard of care, on the progression of kidney disease in subjects with type 2 diabetes mellitus and the clinical diagnosis of diabetic kidney disease.

The purpose of this study is to evaluate whether finerenone is effective and safe in treating patients with type 2 diabetes mellitus and Diabetic Kidney Disease (DKD) in addition to regular therapy.
Kim Hitz at khitz1@pennstatehealth.psu.edu or 717-531-4924
All
18 year(s) or older
This study is NOT accepting healthy volunteers
Hide eligibility criteria
Inclusion Criteria:
type 2 diabetes
diabetic kidney disease
treatment with ACE or ARB
Exclusion Criteria:
HbA1c > 12%
uncontrolled hypertension
dialysis
current or scheduled kidney transplant
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NCT02540993
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Study Locations

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Location
Hershey, PA

Dining with Diabetes in Pennsylvania

Penn State Extension's Dining with Diabetes program is an evidence-based community education program for people with or at risk for type 2 diabetes. The program teaches participants how to prevent or manage their disease by providing practical knowledge and strategies to make the necessary lifestyle changes that will lead to healthier living and reduction in the risk of complications. The overall goals and objectives of the program are as follows: Increasing knowledge of healthy food choices for families with or at risk for diabetes Promoting behavior changes by offering demonstrations and tasting of healthy food. Increasing knowledge of essential medical tests associated with diabetes management. Promoting physical activity as a component of diabetes control. Encouraging self-management and self-efficacy skill. Connecting participants to their healthcare providers for long-term follow-up. The program is designed to meet 4 consecutive weeks and then a 3 month follow-up. Participants A1c and blood pressure are taking at the first and follow-up classes. Classes consist of a nutrition lesson, physical activity, cooking demonstration and food tasting.
Debra Griffie at dab210@psu.edu or 610-489-4315
All
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Individulas with type 2 diabetes
individuals with pre-diabetes
individuals at risk of developing type 2 diabetes
Exclusion Criteria:
under the age of 18
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N/A
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Study Locations

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Location
Altoona, PA
Carlisle, PA
DuBois, PA
Erie, PA
Greater Philadelphia Area, PA
Greater Pittsburgh Area, PA
Hazleton, PA
Hershey, PA
Reading, PA
State College, PA
Wilkes-Barre/Scranton Area, PA

Patient Perceptions of Micro-Management of Insulin

The purpose of this project is to understand how people with type 1 diabetes (T1D) make moment-to-moment decisions about their insulin therapy, specifically whether to administer a dose of insulin at any given time and how much insulin to deliver. In this study, we will interview participants about a survey we developed (based on the initial IRB submission) regarding events that trigger decisions that need to be made about insulin and the kinds of decisions people make about insulin.
Heather Stuckey at hstuckey@pennstatehealth.psu.edu or 717-531-0003
All
18 year(s) or older
This study is NOT accepting healthy volunteers
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Inclusion Criteria:
Type 1 diabetes (self-reported)
Taking >3 multiple daily insulin injections (long-acting and short-acting) or insulin pump
At least one year on insulin
Exclusion Criteria:
Cannot conduct the interview in English
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N/A
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