Refine your search

Search Results within category "Mental & Behavioral Health"

Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.

Search all categories

Suggestions within category "Mental & Behavioral Health"


7 Study Matches

Imaging and Depression with or without MS

A study looking at the neural and genetic correlates of depression. Presently, the current study is looking to recruit individuals for two separate groups: 1. MS but NO history of depression 2. Depression but NO history of MS or neurological disease. The purpose of the study is to look at patterns of brain structure and function in individuals with depression and compare them to those with MS. We will explore how any differences we find contribute to more problems with depression in MS and see how such differences might lead to better treatment options for depression.
Cristina Roman at car342@psu.edu or 814-865-5578
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Between the ages of 30-65
Able and willing to undergo an MRI
Able to travel to State College for the Study
Exclusion Criteria:
Current psychotherapy treatment for depression
Started anti-depressant medication in the last 2 months
Diagnosis of bipolar disorder, schizophrenia, or significant neurocognitive impairment
Very severe depression that would interfere with the ability to participate or suicidal ideations
Unable to undergo an MRI (metal in your body)
Mental & Behavioral Health
  Email this study information to me
  Contact the study team
  Show all 1 locations

Study Locations

Hide all locations
Location
State College, PA

Deprexis Study: An online program to reduce depression in MS – a phase III international multicenter randomized controlled trial

An online program to reduce depression in MS – a phase III international multicenter randomized controlled trial
Deprexis Team Roman at mhc147@psu.edu or 814-865-5578
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT02740361
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Diagnosis of Multiple Sclerosis
Current Depression
No current treatment for depression
Internet access
Between the ages of 18-65
Exclusion Criteria:
No diagnosis of MS
No current psychotherapy for depression
No substantial neurocognitive impairments
Started anti-depressants in the last 2 months
Neurology, Mental & Behavioral Health
  Email this study information to me
  Contact the study team
  See more information
  Show all 1 locations

Study Locations

Hide all locations
Location
State College, PA

Examining Maternal Reward Responsiveness and the Intergenerational Risk for Depression

Children of depressed mothers are at high risk for developing depression, particularly as youth age into adolescence, yet relatively little is known about the mechanism underlying risk for depression in youth with depressed mothers. The present study examines maternal reward responsiveness, measured across neurophysiological, behavioral, and self-report measures as a marker of depression in mothers of adolescents. Associations between maternal reward responsiveness and parenting difficulties often associated with maternal depression, as well as adolescent functioning will be examined, to explore the clinical impact of maternal reward responsiveness on the intergenerational transmission of depression.
All
All
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Female adults 18 years and above with an adolescent child aged 13-16 years
Capacity for informed consent
Fluent in verbal and written English
Adolescent between the ages of 13 and 16 years (inclusive)
Exclusion Criteria:
Diagnosis of autism spectrum disorder, substance use disorders, schizophrenia or other psychotic disorder
Any hearing or visual impairments
Investigator discretion regarding ability to participate in the study
Children's Health, Mental & Behavioral Health, Women's Health
  Email this study information to me
  Contact the study team
  Show all 1 locations

Study Locations

Hide all locations
Location
Hershey, PA

Assessment of Endothelial Function in Post-Menopausal Women with Depression

The goal of this project is to understand the contribution of depression on blood vessel function in post-menopausal women, a population at heightened risk for cardiovascular disease. Currently, little is known about the combined impact of depressive symptoms and the effects of reproductive aging on blood vessel function. As such, there is a greater need to characterize blood vessel function in post-menopausal women with depressive symptoms. Participants depressive symptoms will be assessed and non-invasive vascular measures will be performed.
Jigar Gosalia at jzg691@psu.edu or 814-863-3182
Female
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Post-menopausal women who are at least 1 year removed from their final menstrual period and between the ages of 50 and 80
Individuals with moderate to severe depression as reflected by Patient Health Questionnaire (PHQ-9) score of 10 or greater for the depressed post-menopausal women group
We also need non-depressed healthy post-menopausal women are needed as well for control group comparisons
Free from blood-pressure lowering medication and lipid lowering medication
Exclusion Criteria:
Individuals with any overt cardiovascular, metabolic, hematologic, pulmonary, renal, musculoskeletal, and/or neurological disease(s).
Users of any tobacco and/or nicotine products (smokers, chewing tobacco, nicotine-containing patches/gum, smokeless cigarettes)
Individuals taking hormone therapy
Individuals with a BMI > 35
Heart & Vascular, Mental & Behavioral Health, Women's Health
  Email this study information to me
  Contact the study team
  Show all 1 locations

Study Locations

Hide all locations
Location
State College, PA

Inflammatory, Behavioral and Neural Markers of Anhedonia in Major Depressive Disorder

The purpose of this study is to investigate the underlying biological causes of the loss of pleasure in individuals diagnosed with depression. This study will examine brain, behavioral, and inflammatory markers of depression. Participants will answer questions, give blood and saliva, undergo fMRI and perform computer tasks. The study is a 1 time appointment lasting 3hrs and participants will be compensated $130. The study is also recruiting healthy controls with no history of major mental illnesses.
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Major Depressive Disorder
Failed two lines of anti depressant treatment
Between 18-65 years of age
Exclusion Criteria:
Any metallic implant
Bipolar Disorder or Psychotic Disorder
Heavy alcohol or recreational drug use
Inflammatory disease like Lupus, Rheumatoid Arthritis
Infectious Diseases & Immune System, Prevention, Mental & Behavioral Health
  Email this study information to me
  Contact the study team
  Show all 1 locations

Study Locations

Hide all locations
Location
Hershey, PA

Families Being Supportive Together

This project studies the different ways that caregivers respond to their teens when teens ask for support. The study focuses on youth with and without a risk of developing depression and anxiety. We study how youth ask for help from their caregivers and how caregivers respond in their daily lives by observing family interactions at home. The ultimate goal of this study is to reveal how modern families support their teens and how communication among immediate family members can impact stress, mood, and mental health.
Sunny Bai at sub1164@psu.edu or 814-867-6488
All
All
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Family has youth between ages 12-15 yo
Parent and youth live together at least 5 days/week
Parent has an active driver's license
Family has car that they use regularly
Primary language spoken at home is English
Exclusion Criteria:
Youth or parent has current diagnosis of severe mental illness (ex: Bipolar, OCD, Alcohol/Substance use disorder, Eating disorder, Psychotic disorder)
Youth has developmental disability (Autism spectrum disorders)
Youth or parent has had a suicide attempt, or intensive care (inpatient, partial hospitalization, daily outpatient) care for emotional or behavior problems in the past 12-months
Other social (ex: homelessness) or medical conditions that make participation difficult
Children's Health, Prevention, Mental & Behavioral Health
  Email this study information to me
  Contact the study team
  Show all 2 locations

Study Locations

Hide all locations
Location
Harrisburg, PA
State College, PA

Depressive Symptomatology and Inflammation

The purpose of this research is to investigate the associations between depressive symptoms and inflammation. The researchers are studying how specific symptoms of depression (such as fatigue, sadness, impaired concentration, and loss of pleasure) are related to markers of inflammation, which is a key component of our immune system. Volunteers with depressive symptoms, as well as volunteers without depressive symptoms are needed for this research study. This study includes an online survey to determine eligibility and one in-lab visit. Participants who are eligible will be scheduled for one in-lab visit (2.5-3h for participants with depressive symptoms & 1-2h for participants without depressive symptoms), where they will be asked to answer surveys with questions related to depressive symptoms and complete a number of tasks (using an iPad and a touch screen phone) that measure thinking skills including attention, memory and reaction time. Participants will also undergo a single blood draw to assess inflammatory markers.
Brooke Mattern at bcm5214@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Men and women between the ages of 18-50 years
Have been diagnosed with depression or may experience depressive symptoms (e.g., decreased energy, sadness)
If female: pre-menopausal, not pregnant or nursing
Fluent in English
Exclusion Criteria:
Chronic inflammatory or autoimmune disorders
started antidepressants in the last month
Current eating disorder
Taking anti-inflammatory agent (e.g., Advil), lipid-lowering agents (e.g., statins) everyday within the past month
Diagnosis of bipolar disorder, schizophrenia, or other psychotic disorders
Mental & Behavioral Health
  Email this study information to me
  Contact the study team
  Show all 1 locations

Study Locations

Hide all locations
Location
State College, PA