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Search Results within category "Sports Medicine"

Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.

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11 Study Matches

Site for Poly-omic predictors of symptom duration and recovery for adolescent concussion

Using micro-RNA in saliva coupled with survey data as a prognostic tool with the ability to guide clinical management of concussions
Brennen Harding at bharding@pennstatehealth.psu.edu or 717-531-5656
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All
This study is NOT accepting healthy volunteers
NCT04582682
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Inclusion Criteria:
13-18 years old
Diagnosis of concussion
Exclusion Criteria:
more than 48 hours after injury
Neurology, Sports Medicine
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Hershey, PA

Predicting Concussion Outcomes with Salivary miRNA

The purpose of this study is to identify changes in salivary micro ribosomal nucleic acid (miRNA) expression that are predictive of symptom duration and severity following mild traumatic brain injury (mTBI) in children. The primary endpoints of this study are as follows: 1) Characterization of brain-related miRNA in the saliva of 250 children with mTBI and 200 age- and gender-matched controls between the ages of five and twenty-three years. 2) Identification of a set of salivary miRNAs that is predictive of duration and severity of mTBI symptoms.
Brennen Harding at bharding@pennstatehealth.psu.edu or 717-531-5656
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All
This study is also accepting healthy volunteers
NCT02901821
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Inclusion Criteria:
5 to 23 years of age
Seen in the Penn State Pediatric Concussion Clinic within 2 weeks of most recent concussion
Exclusion Criteria:
Does not speak english
Periodontal disease
Ongoing seizure disorder, or other neurologic disorder
Drug or alcohol dependency
clinical diagnosis of severe TBI
Children's Health, Neurology, Sports Medicine
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Hershey, PA

Interlimb differences in Motor Control and Learning

This study examines how each brain hemisphere contributes to motor control and coordination. Participants play virtual reality/computer games to look at how their arms move during different activities.
Brooke Fosaaen at sainburglab@psu.edu or 814-865-7937
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
over the age of 18
Exclusion Criteria:
neurological disease
upper-extremity orthopedic injuries that interfere with participation
Neurology, Sports Medicine, Muscle & Bone
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Hershey, PA
State College, PA

The effect of positive and negative self-talk on postural control and balance among college-aged adults

The project will aim to examine the role of self-talk or positive self-motivation on controlling body balance while performing specific balance tasks. Previous research has examined how self-talk can impact performance on sport-related movements (i.e. golf or tennis swings), but only a small portion of studies have examined how this strategy can improve balance. These studies have looked at specific populations, such as individuals with learning disabilities and individuals with limb amputations, so the question remains if the self-talk strategy can impact how generally healthy individuals control balance. Participants will test the self-talk strategies while performing tasks in natural environments. These tasks will be specifically designed to elicit postural responses. Therefore, the purpose of this study will be to examine the effects of positive and negative self-talk on balance performance in college-aged adults.
Fabricio Saucedo at Fns5045@psu.edu or 814-949-5703
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
must be healthy and 18-25 years of age
must be healthy and must have no known history of musculoskeletal, neurological, cardiovascular, or pulmonary impairment
must not use any sedative of any type
must understand English
Exclusion Criteria:
history of musculoskeletal, neurological, cardiovascular, or pulmonary impairment
Report use of a pacemaker
Report sedative use
Report an inability to tolerate standing positions of greater than 30 minutes
resting heart rate (HR) > 85% of age-predicted maximal heart rate
Men's Health, Sports Medicine, Women's Health
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Location
Altoona, PA
State College, PA

The changes in insulin resistance and metabolic health among young, middle aged, and older adults meeting the current aerobic exercise training recommendations.

The overall purpose of this research is to evaluate the difference the national cardiorespiratory exercise recommendations have on metabolic and cardiovascular health over 6 weeks in previously sedentary young, middle aged, and older adults matched for obesity. The participants will complete moderate intensity exercise for 30 minutes per day, 5 days per week for 6 weeks. Pre- and post-intervention testing will be completed to evaluate changes in metabolic and cardiovascular health.
Nicole Gilbertson at nmg46@psu.edu or 814-949-5016
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
Ages 19-24 and 45-79 years
Physically inactive
Able to walk for at least 30 minutes
Obese
Exclusion Criteria:
Currently participating in planned, structured physical activity
Lost or gained more than 10 lbs in 6 months
Females currently pregnant or breastfeeding
Currently smoking/using tobacco products or have within the past 6 months
Having signs/symptoms or diagnosed with cardiovascular, lung, kidney, metabolic, or mental health disease
Heart & Vascular, Sports Medicine, Diabetes & Hormones
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Location
Altoona, PA

Evaluation of Changes in Mechanical Properties after Achilles Tendon Repair

Many negative consequences of Achilles tendon ruptures, such as tendon elongation and calf muscle atrophy, develop during the first weeks of healing after a rupture. In order to develop new therapy approaches to address those issues, it is necessary to understand the changes happening in the tendon during the first weeks of recovery. This study will use ultrasound imaging to evaluate the change in mechanical properties of the healing tendon. This properties will be used in the future to develop new therapies focused on preventing muscle atrophy and improving tendon healing.
Andrea Horne at ahorne@pennstatehealth.psu.edu or 717-531-7127
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
Achilles tendon rupture
Exclusion Criteria:
Diabetes
Poor blood circulation to the legs
Any condition impairing normal healing
Sports Medicine, Muscle & Bone
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Location
Hershey, PA
State College, PA

Foot mechanics during gait with load carriage and toe elevation

This experimental study will investigate foot joint function during walking and running and/or hopping and performing heel raises. Participants will walk and run and/or complete heel raises with mass added to their body and will walk and run and/or hop with a plastic wedge secured to the underside of their toes.
Daniel Davis at djd426@psu.edu or 307-680-8816
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Age 18-35
Run > 10 kilometers/week for past 6 months
If participant does not fit running criteria: Lifted weights of at least one bodyweight using barbell >= 2x/week for past 6 months
Exclusion Criteria:
Have had previous lower limb surgery
Experienced pain with walking, running, or (if applicable) weightlifting in past 6 months
Have had plantar fasciitis
Have osteoarthritis in lower limb
Have had diabetes 1 or 2
Sports Medicine, Muscle & Bone
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Study Locations

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Location
State College, PA

AYA-UNITE (Utilizing Novel Information Technology to Promote Exercise and Well-Being) in Adolescents and Young Adults with Cancer

Adolescents and young adults (AYAs) with cancer have many needs for supportive care that differ from younger and older patients. This includes age-appropriate psychological support for management of distress, as well as supports for the social isolation many AYAs experience. One exciting intervention that may provide AYAs with cancer improved psychosocial support, as well as increased physical strength, is physical activity. This feasibility project aims to evaluate the safety, feasibility and acceptability of a physical activity training in AYAs with cancer delivered via a socially interactive videoconferencing platform.
Pooja Rao at prao2@pennstatehealth.psu.edu or 717-531-6012
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All
This study is NOT accepting healthy volunteers
NCT03778658
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Inclusion Criteria:
Participant age 15-29 years old at time of cancer diagnosis

Participant diagnosis of cancer who is currently undergoing active treatment for cancer, or who is within 3 years of end of cancer treatment at the time of enrollment
Participant must have access to a computer or smartphone
Exclusion Criteria:
Cardiovascular or respiratory disease

Absolute contraindication to exercise
Pregnant women
Patients with relapsed cancer
atients who have undergone allogeneic stem cell transplant
Sports Medicine, Mental & Behavioral Health, Cancer
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Site for Refinement of a rapid saliva miRNA diagnostic test for concussion

The purpose of this research is to use saliva swab as a tool to diagnosis concussions and be able to differentiate a concussion and other medical conditions with the similar symptoms.
Brennen Harding at bharding@pennstatehealth.psu.edu or 717-531-5656
All
All
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
13-22 years old
Diagnosis of concussion
Exclusion Criteria:
< 72hrs after TBI
Children's Health, Neurology, Sports Medicine
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Study Locations

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Location
Hershey, PA

Identification of Critical Thermal Environments for Aged Adults

The earth’s climate is warming, and the number of heat waves has increased in recent years. At the same time, the number of adults over the age of 65 is growing. Humans sweat and increase blood flow to the skin to cool their body when they get hot. Older adults do not do this as well as young adults. This makes it harder to safely exercise in warm and/or humid conditions. It is important to learn about safe limits of heat and humidity for older adults to exercise. Also, nearly 40% of adults over age 50 take aspirin to lower their risk for heart disease. Our lab has shown that aspirin lowers the control of body heat. In this study, we will determine critical temperature and humidity environments above which normal body temperature cannot be maintained in young and older adults. We will also look at how aspirin may change critical temperature and humidity thresholds in older adults.
Susan Slimak at sks31@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT04284397
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Inclusion Criteria:
Healthy subjects 18-35 or 40-85 years of age
Asymptomatic and no signs/symptoms of disease
Exclusion Criteria:
Have any conditions to advise against low-intensity physical activity
History of Crohn's disease, diverticulitis, or other similar gastrointestinal disease
Medications that could alter cardiovascular responses or body temperature regulation during exercise (blood pressure reducers, fever reducers, anti-depressants, etc.)
Tobacco or recreational drug use
Post-menopausal women taking hormone replacement therapy
Heart & Vascular, Sports Medicine
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Study Locations

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Location
State College, PA

Effect of Blood Flow Restriction Therapy on Knee Flexor Strength in Healthy Young Adults

This study is seeking to enroll participants who are between the ages of 18-35 that are healthy, physically active. Eligible participants will complete laboratory testing related to knee function, which will include hamstring strength assessment, hamstring tendon stiffness and muscle thickness analysis via ultrasound, hamstring flexibility, and single leg jump testing. Participants will be assigned to one of three groups. Depending on group assignment, participants will either complete a 4-week knee flexor focused training program using a technique called blood flow restriction (BFR) therapy in one limb and normal high intensity training in the other limb (same exercises within each group), or will receive no treatment/intervention and complete normal daily activities. The BFR therapy intervention will consist of three sessions per week (twelve sessions total) that will focus on increasing hamstring strength. Following the 4-week period, all participants will return to the laboratory to repeat similar laboratory testing. Comparisons of the data collected will be made between groups and limbs before and after the 4-week intervention period
Mark Colapietro at mac6033@psu.edu or 814-381-5093
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
All genders age 18-35
No history of significant knee pathology or lower extremity injury that required surgery in either limb
No history of hamstring strains or musculoskeletal injuries in past three months
No history of back pain in past 3 months
Physically active/ good general health
Exclusion Criteria:
History of lower extremity injury or fracture that required surgery
History of acute musculoskeletal injury in past 3 months for both limbs
History of hypertension (blood pressure greater than 130/80 mmHg), diabetes mellitus, compromised vascular circulation, or cancer
Individuals with neurological or other health condition that would limit their ability to flex the knee beyond 90 degrees
Participants with an allergic reaction to ultrasound gels
Sports Medicine, Muscle & Bone
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Study Locations

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Location
State College, PA