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Suggestions within category "Muscle & Bone"


17 Study Matches

Tongue movement in adults with motor speech disorder

Tongue movement in adults with motor speech disorder
Jimin Lee at jxl91@psu.edu or 814-863-5338
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
be a native speaker of American English
have normal hearing
between 18 and 40 years of age
have no known speech, language, learning or neurological disorders
have very little experience in communicating with people that have motor speech disorders
Exclusion Criteria:
younger than 18 years of age; older than 40 years of age
Not a speaker of American English only
With hearing impairment
have neurologic and/or speech/language disorders
have extensive experience in communicating with people that have motor speech disorders
Neurology, Muscle & Bone, Language & Linguistics
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Hershey, PA
State College, PA

Prediction of Muscle Force Generation using Ultrasound Imaging and Computational Simulations

The objective of this study is to develop and validate a method to predict force production of individual muscles from ultrasound measurements of muscle stiffness, size, and structure. We will place acupuncture needles to the muscles and applied a small amount of current to induce contraction. Force and ultrasound measurements will be performed during muscle contraction. This process will be done in three muscles, one in the arm and two in the leg.
Daniel Cortes at researchsubjects@mne.psu.edu or 814-863-3103
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Healthy individuals without history of muscle disease or injury
Exclusion Criteria:
Pregnant women
Allergy to ultrasound gels
contraindications to MRI scans
Muscle & Bone
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Location
State College, PA

Physical Therapists Role in Promoting Physical Activity for People with Chronic Physical Disabilities

We plan to conduct a qualitative study exploring perspectives of physical therapists and people with disability regarding physical activity promotion
Jacob Corey at jjc6062@psu.edu or 814-865-1691
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
At least 18 years of age
Fluent in english
Individual with a physical disability (eg. limb amputation, spinal cord injury, spinabifida, cerebralpalsy, arthritis, motor impairment)
Has participated in physical therapy in the last year
Exclusion Criteria:
Under the age of 18
Does not speak fluent english
does not have a physical disability
Has not participated in physical activity in the last year
Arthritis & Rheumatic Diseases, Neurology, Muscle & Bone
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The Use of Micro-Doppler Radar to Identify Service Members at Risk for Musculoskeletal Injury: A Gold Standard Comparison

The purpose of this research study is to see if we can use micro-doppler signal technology to determine if someone has had an ACL reconstruction in the past. We will do this by comparing a group of people who have had the surgery against a group who has never had this surgery to see if this technology can tell the difference.
Cayce Onks at conks@pennstatehealth.psu.edu or 717-531-8187
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Ages 18-40
ACL Group: ACL Reconstruction surgery 9-24 months prior and approved to return to normal activities
Control group: No history of lower extremity surgery
Able to provide consent and read/write in English
No current musculoskeletal injuries
Exclusion Criteria:
Prisoner
Pregnant person
Below age 18 or above Age 40
Unable to provide consent or read/write in english
Unable to perform movements consistent with daily activities such as jogging, jumping, or moving from sit to stand
Prevention, Sports Medicine, Muscle & Bone
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Hershey, PA

AWS-PSU: Active Women's Study at Penn State University

AWS-PSU: Active Women's Study at Penn State University This research study is being conducted to evaluate the impact of exercise and reproductive function on bone strength. Eligible young women (age 18-30) are those that are generally healthy and either a) exercising and experiencing regular or irregular menstrual cycles, or b) not exercising and experiencing regular menstrual cycles.
Nicole Aurigemma at nca11@psu.edu or 814-863-4488
Female
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Regular or irregular menstrual cycles
Age 18-30
BMI between 16-29.9
No hormonal contraception for 6 months
Exclusion Criteria:
Smoking
Currently using medication impacting bone
Food & Nutrition, Muscle & Bone, Women's Health
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Location
State College, PA

Interlimb differences in Motor Control and Learning

This study examines how each brain hemisphere contributes to motor control and coordination. Participants play virtual reality/computer games to look at how their arms move during different activities.
Brooke Fosaaen at sainburglab@psu.edu or 814-865-7937
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
over the age of 18
Exclusion Criteria:
neurological disease
upper-extremity orthopedic injuries that interfere with participation
Neurology, Sports Medicine, Muscle & Bone
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Hershey, PA
State College, PA

The Effects of Aircraft Seat Width on Passenger Comfort

The objective of this research is to determine the relationship between aircraft seat width and passenger comfort. Airlines are reducing the sizes of seats and improving their ability to fly planes at or near capacity. The combined effect is to decrease the quality of the experience of passengers. This work will help us to understand the degree to which comfort has been reduced.
Ritwik Biswas at AirplaneResearch@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
We are particularly interested in small and large participants.
You must be a healthy adult aged 18 years or older.
Exclusion Criteria:
Individuals under 18 years of age are not eligible.
Muscle & Bone, Mental & Behavioral Health
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State College, PA

In Vivo Assessment of the Effect of Bench Press Exercise on Glenohumeral Cartilage Deformation

The goal of this project is to investigate the impact of high-load exercise, like the bench press with a large amount of weight as opposed to an exercise like the push-up, on the shoulder joint cartilage , tissue on the ends of our bones that cushion and protect them from damage, as well as assess how well qualitative assessments of personal pre- and post-exercise pain coordinate with cartilage structure. We predict that there will be a significant difference in pre- and post-exercise cartilage thickness.
Andrea Myers at amyers1@pennstatehealth.psu.edu or 717-531-3892
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Healthy adults between the ages of 18-35
English speaking
Exclusion Criteria:
Previous injury or surgery to either shoulder
Inability to undergo MRI
Inability to perform exercise protocol
Pregnant
Under the age of 18 or over the age of 35
Muscle & Bone
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Location
Hershey, PA

Penn State Exercising Women's Study

This study aims to assess energy status in young sedentary and exercising women as it is related to menstrual status, bone health, psychological health, sleep variables, and cardiovascular function.
Ana Carla Chierighini Salamunes at akc6247@psu.edu or 814-863-4488
Female
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Women
Age 18-30 years
Body Mass Index between 16-29.9 kg/m2
For sedentary participants: less than 2 hours of purposeful exercise per week and regular menstrual cycles for the last 6 months (i.e. cycles between 26 and 35 days in length)
For exercising participants: exercise at least 2 hours per week AND/OR participate in collegiate athletics. Exercising participants can have regular or irregular menstrual cycles for the last 6 months.
Exclusion Criteria:
Pregnant or lactating
Currently a smoker or history of regular smoking
Taking any hormonal therapy in the past six months
Serious or chronic health condition (including heart condition, thyroid illness, metabolic disease)
Hysterectomy or oophorectomy
Food & Nutrition, Muscle & Bone, Women's Health
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Location
State College, PA

A volunteer study to determine the anatomical distribution of injectate, the extent of sensory block, and the pharmacokinetics of ropivacaine following Erector Spinae Plane (ESP) blocks.

This study will recruit healthy volunteers to determine the effect of a peripheral nerve block. The participants will get an injection in their back muscle after an intravenous line is placed in their hand or arm. After the injection they will have two MRI done at 30 and 90 minute time intervals. A half tablespoon of blood also will be taken through the IV line already placed 6 times during the study period starting just before to Peripheral nerve block placement up to four hours post injections. They will be discharged from the study after half an hour of the last blood sample. During this whole process they will be monitored for their blood pressure, oxygen saturation and other effects related to the procedure.
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT03476642
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Inclusion Criteria:
Healthy adults ages 18 to 60
Weight between 55kgs (~120lbs) and 100kgs (~220lbs)
Height 160cms (~5ft 3in) to 190cms (~6ft 3in)
Exclusion Criteria:
Pregnant females, chronic medical condition requiring medication
History of previous major spinal, abdominal or thoracic surgery, 4. Congenital abnormalities of the spine, back, thorax or abdomen
History of major trauma to the thorax or abdomen; 6. Allergy to ropivacaine or other amide local anesthetics
The presence of any metallic implant in their body, 9. Allergy to Gadolinium radiological contrast agent
Any contraindication to magnetic resonance imaging as determined by completion of a standard questionnaire administered to all patients undergoing magnetic resonance imaging.
Prevention, Muscle & Bone, Pain Management
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Hershey, PA

Foot mechanics during gait with load carriage and toe elevation

This experimental study will investigate foot joint function during walking and running and/or hopping and performing heel raises. Participants will walk and run and/or complete heel raises with mass added to their body and will walk and run and/or hop with a plastic wedge secured to the underside of their toes.
Daniel Davis at djd426@psu.edu or 307-680-8816
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Age 18-35
Run > 10 kilometers/week for past 6 months
If participant does not fit running criteria: Lifted weights of at least one bodyweight using barbell >= 2x/week for past 6 months
Exclusion Criteria:
Have had previous lower limb surgery
Experienced pain with walking, running, or (if applicable) weightlifting in past 6 months
Have had plantar fasciitis
Have osteoarthritis in lower limb
Have had diabetes 1 or 2
Sports Medicine, Muscle & Bone
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Location
State College, PA

Active Men's Study

Description: This research study is to assess energetic status, reproductive health, and bone health in a population of young exercising men. Secondarily, this study will also explore how diet, fitness, cardiovascular function, eating behaviors, stress, cognitive function, and sleep related to energy and reproductive outcomes in exercising men. Eligible young men (age 18-35) are those who are generally healthy and either a) exercising or b) not exercising.
Emily Lundstrom at eal259@psu.edu
Male
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Age 18-35 years
BMI between 16-29.9 kg/m2
Non-smoker
For sedentary participants: less than 150 minutes of purposeful exercise per week
For exercising participants: at least 150 minutes of purposeful exercise per week (moderate to high intensity aerobic and/or resistance training).
Exclusion Criteria:
BMI >29.9 kg/m2 or <16 kg/m2
Procedures using contrast material within the past 7 days, including X-rays, MRI scans, CT scans, barium studies, nuclear medicine exams.
Currently a smoker or history of regular smoking
Prostheses
Vasectomy
Men's Health, Sports Medicine, Muscle & Bone
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State College, PA

Actuation and sensing of ultrasonic guided waves in shin bone using shear wave acoustic emission sensors.

The purpose of this study is to evaluate the effectiveness of ultrasound to assess the current state of the health of shin bones. Ultrasound will be sent along the length of both the shin bones of a volunteer, using a pair of sensors. Physical wave propagation parameters will be derived from the collected data. For this study: 1. We will ask you to briefly answer a list of four questions related to your physical activity and bone fracture history, 2. We will first measure your weight and height, 3. You will be asked to sit on a chair with legs resting comfortably on a stage, 4. We will then ask you to keep your legs below the knee free from garments, 5. We will also ask you to not wear shoes while we make the measurements, 6. We will position the sensors on your leg and acquire data, one leg at a time. Your participation will last for 35 minutes and includes only one study visit per volunteer.
Anurup Guha at anurup@psu.edu or 814-321-7407
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
physically able to walk
above 18 years of age
no recent fracture history
able to keep the region below the knee free of clothes
Exclusion Criteria:
pregnant women
those unable to provide consent
children
prisoners
less than 18 years old
Men's Health, Muscle & Bone, Women's Health
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State College, PA

Evaluation of calf muscle size and structure after an Achilles tendon rupture

The objective of this study is to compare to different methods of measuring the size of calf muscles: magnetic resonance (MRI) and ultrasound imaging. Participant will undergo a MRI scan (about 1 hour) and an ultrasound imaging session (about 1 hour). Images obtained from patients with Achilles tendon rupture will also be used to determine the feasibility of quantifying damage to the soleus muscle.
Daniel Cortes at dhc13@psu.edu or 814-863-3103
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT04727047
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Inclusion Criteria:
Healthy individuals
Exclusion Criteria:
Contraindications to MRI
Previous Achilles injury (only for healthy individuals)
Muscle & Bone
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State College, PA

Effect of Blood Flow Restriction Therapy on Knee Flexor Strength in Healthy Young Adults

This study is seeking to enroll participants who are between the ages of 18-35 that are healthy, physically active. Eligible participants will complete laboratory testing related to knee function, which will include hamstring strength assessment, hamstring tendon stiffness and muscle cross sectional area analysis via ultrasound. Participants will be assigned to one of three groups. Depending on group assignment, participants will either complete a 4-week knee flexor focused training program using a technique called blood flow restriction (BFR) therapy in one limb and normal high intensity training in the other limb (same exercises within each group), or will receive no treatment/intervention and complete normal daily activities. The BFR therapy intervention will consist of three sessions per week (twelve sessions total) that will focus on increasing hamstring strength. The first session will also include 1 repetition max testing for the exercises being completed during the intervention. Following the 4-week period, all participants will return to the laboratory to repeat similar laboratory testing. Comparisons of the data collected will be made between groups and limbs before and after the 4-week intervention period
Mark Colapietro at mac6033@psu.edu or 814-381-5093
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT00000000
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Inclusion Criteria:
All genders age 18-35
No history of significant knee pathology or lower extremity injury that required surgery in either limb
No history of hamstring strains or musculoskeletal injuries in past three months
No history of back pain in past 3 months
Physically active/ good general health
Exclusion Criteria:
History of lower extremity injury or fracture that required surgery
History of acute musculoskeletal injury in past 3 months for both limbs
History of hypertension (blood pressure greater than 130/80 mmHg), diabetes mellitus, compromised vascular circulation, or cancer
Individuals with neurological or other health condition that would limit their ability to flex the knee beyond 90 degrees
Participants with an allergic reaction to ultrasound gels
Sports Medicine, Muscle & Bone
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State College, PA

Metabolic Alterations of the Semitendinosus Muscle After Tendon Harvest for Anterior Cruciate Ligament Reconstruction

This is a cohort study examining the changes in the muscle that occur following ACL injury and reconstruction. This study aims to determine if significant changes to the muscles properties occur as a result of the graft taken for ACL reconstruction, and whether or not these changes serve as a risk factor for further injuries. This study will examine the muscles ability to use oxygen non-invasively, an important determinant of muscle endurance and allow for comparisons of this between individuals with ACL-reconstruction surgery and healthy, non-injured adults.
Jigar Gosalia at jzg691@psu.edu
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
ACL tear within last 12-36 months
Full rehabilitation
autograft taken from hamstring tendon
other autografts may be considered
Recreationally active
Exclusion Criteria:
Other major knee injury (i.e. MCL tear)
Muscle & Bone
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State College, PA

The effect of muscle shortening on the force-length characteristics of neighboring inactive muscles

We are trying to better understand the ways in which people contract their muscles. Specifically, we want to learn more about how connections between our muscles influence how they produce forces. Participants in this study will have their calf muscle group activated while we record the individual muscles' electrical activity and the length of the muscle fibers. This research will help us to understand the underlying mechanical function of muscles in a more realistic context. This understanding may also have profound implications for current computer models of muscles, which most often ignore the connectivity between muscles.
Jonas Rubenson at jxr75@psu.edu or 814-867-6209
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
18-40 years old
Exclusion Criteria:
chronic or acute leg injury in last 12 months
heart condition
chest pain during exercise
balance or dizziness problems
prescribed drugs for blood pressure or heart condition
Muscle & Bone
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State College, PA