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Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (CHAMP)
A study of the safety and effectiveness of an unrelated cord blood transplantation versus haploidentical transplantation for severe aplastic anemia.
Inclusion Criteria:A diagnosis of severe aplastic anemia.
Less than 75 years of age at time of enrollment.
Failed at least one trial of immunosuppressive therapy.
Exclusion Criteria:Inherited bone marrow failure syndromes.
Diagnosis of myelodysplastic syndrome.
Prior allogeneic stem cell transplant or solid organ transplant.
Blood Disorders, Children's Health