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Search Results within category "Infectious Diseases & Immune System"

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Suggestions within category "Infectious Diseases & Immune System"


Study matches: 6

Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.


Procalcitonin Antibiotic Consensus Trial

The study objective is to target emergency department (ED) patients with clinically diagnosed lower respiratory tract infection (LRTI) and test the effects of implementation of a procalcitonin antibiotic guideline for LRTI.
Nancy Campbell RN at ncampbell1@pennstatehealth.psu.edu or 531-1707 ext. 3
All
18 year(s) or older
This study is NOT accepting healthy volunteers
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Inclusion Criteria:
Lower respiratory lung infection < 28 days
Exclusion Criteria:
no antibiotic use for 72 hours before enrollment
no other infections
no cancer
no dialysis
no major surgery in past 7 days
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NCT02130986
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Location
Hershey, PA

An Investigator-Initiated, Phase II, Randomized, Withdrawal Study of Mycophenolate Mofetil (MMF) in Patients with Stable, Quiescent Systemic Lupus Erythematosus (SLE)

This study is for patients diagnosed with systemic lupus erythematosus (SLE) who are taking MMF now and have been taking MMF for 1-2 years and your disease is not active. The purpose of this research study is to find out if patients who have been on MMF for 1 to 2 years and whose disease is quiet can safely stop their MMF medication. This could help standardize treatment for lupus patients in the long-run. Doctors know that continuing MMF for long periods of time can have side effects and they know that stopping MMF will put patients at a higher risk for flare; we are trying to find out how big this risk is and if it is better to stop or continue taking MMF.
Jamie Carter at jcarter3@pennstatehealth.psu.edu
All
18 year(s) or older
This study is NOT accepting healthy volunteers
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Inclusion Criteria:
Diagnosis of Lupus
Currently taking Mycophenolate
Taking Hydroxychloroquine
Exclusion Criteria:
Taking prednisone greater than 25mg per day
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NCT01946880
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Location
Hershey, PA

Microbiome And Procalcitonin Long term outcomes Epidemiology

An ancillary study to ProACT (IRB# 747 ) to determine the impact of a procalcitonin-antibiotic strategy on the microbiome changes that occur during a time of infection.
Nancy Campbell RN at ncampbell1@pennstatehealth.psu.edu or 717-531-1707 ext. 3
All
18 year(s) or older
This study is NOT accepting healthy volunteers
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Inclusion Criteria:
Lower respiratory lung infection < 28 days
older than 18 yrs
Exclusion Criteria:
antibiotics within the last 72 hours
pregnant
metastatic cancer
severe immunosuppression
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N/A
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Study Locations

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Location
Hershey, PA

A Registry of Patients with Primary Immunodeficiency Disorders

The United States Immunodeficiency Network (USIDNET) Consortium is a group of investigators funded by the National Institutes of Health (NIH) working in association with the Immune Deficiency Foundation (IDF) to conduct a study in which a patient Registry is being developed. The Immune Deficiency Foundation is the national patient organization dedicated to improving the diagnosis, treatment and quality of life of persons with primary immunodeficiency diseases through advocacy, education, and research. The IDF provides administrative support for USIDNET and developed the initial Registry of patients with Primary Immunodeficiency that has grown to become the current Registry.
D. Adriana Andreae, MD at dandreae@pennstatehealth.psu.edu
All
Not specified
This study is NOT accepting healthy volunteers
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Inclusion Criteria:
Must have a known or suspected primary immune deficiency disease, or be a genetic carrier of such a defect
Exclusion Criteria:
Individuals with immunodeficiency associated with HIV infection, chemotherapy or other immunosuppressive therapies
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N/A
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A MULTICENTER OPEN-LABEL STUDY OF ETANERCEPT WITHDRAWAL AND RETREATMENT IN SUBJECTS WITH NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS WHO ACHIEVED ADEQUATE 24 WEEK RESPONSE

To estimate the proportion of subjects who flare within 40 weeks following withdrawal of ETN in subjects who have achieved ASDAS CRP less than 1.3 (inactive disease).
Jamie Carter at jcarter3@pennstatehealth.psu.edu or 717-531-0003 Ext. 283833
All
18 year(s) or older
This study is NOT accepting healthy volunteers
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Inclusion Criteria:
Back Pain
Symptoms longer than 3 months less than 5 years
On a stable NSAID
ages 18-50
Exclusion Criteria:
Radiographic Sacroilitis
Previous treatment with a TNF-a Biologic inhibitor
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NCT02509026
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Study Locations

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Location
Hershey, PA

Cognitive abilities and markers of biobehavioral health: Evaluation of potential bi-directional associations

This study will examine how different ways of thinking and feeling emotions may be related to one's physiology. Participants will complete up to four lab visits (one visit is optional) within approximately three to four months where they will asked to indicate how they experience emotions and how they relate to other individuals in addition to completing brain games (e.g., puzzles, memory tasks). They will also complete a blood draw at each visit and provide saliva samples at one visit. Very little blood will be taken during visits (57 ml; a typical blood donation is approximately 475 ml). Participants will wear a non-invasive strap that measures their heart rate around their upper abdomen (except when sleeping or showering) and complete very brief questionnaires about their mood up to five times daily for two weeks on a cell phone provided to them. Participants can earn up to $300 for completing all study procedures.
Jasmin Guevara at jeg90@psu.edu or 814-865-6598
All
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Age 45 to 70
Able to attend clinic visits
Exclusion Criteria:
Pregnant or breastfeeding
Currently working evening shift
Us of non-steroidal anti-inflammatory drugs (NSAIDs)
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N/A
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Study Locations

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Location
State College, PA