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Search Results Within Category "Smoking, Vaping, Nicotine and Tobacco"

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11 Study Matches

Establishing the effect of flavor on the addictive potential of electronic cigarettes

For the current study, nicotine users will use an electronic cigarette in addition to their usual nicotine source for 4 weeks. The electronic cigarette will contain sweet or tobacco flavored liquid that may or may not contain nicotine. Participants will complete functional magnetic resonance imaging scans at the beginning and end of the study to measure how the brain responds to the electronic cigarette flavor.

There will be two remote visits and two in person visits. There will be a MRI during each in person visit and the subject will be given an study electronic cigarette to use between the two MRI visits.

220

Yes
 

Andrea Hobkirk
abl@pennstatehealth.psu.edu 717-531-5473
Psychiatry and Behavioral Health (HERSHEY)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
NCT03905928
STUDY00011837
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Inclusion Criteria:
21-60 years old
Nicotine Useres
Not currently interested in quitting smoking

Exclusion Criteria:
Unstable or significant medical conditions
Pregnant or nursing
Implanted metal in the body
Smoking, Vaping, Nicotine and Tobacco, Addiction & Substance Abuse
I'm interested
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Hershey, PA ,

Testing the effect of ENDS flavors on Neurotransmission

Tobacco users will be randomized to use electronic cigarettes containing varying levels of nicotine and flavor during laboratory protocols to investigate the effects on the brain and behavior. Subjects will complete surveys, functional magnetic resonance imaging scans, and complete computerized tasks. Eligible participants include daily users of inhaled tobacco products who are at least 21 years old, able to read and write in English, and not planning to quit tobacco use within the next month. Exclusion criteria include: current substance use impairing participation, unstable or significant medical conditions, current use of smoking cessation medication, uncontrolled serious mental illness, and MRI safety or neurological contraindications.

Subjects will taste test a variety of e-cigarette flavorings, answer questions and complete a single MRI.

50

Yes
 

Andrea Hobkirk
Kenneth Houser - at abl@pennstatehealth.psu.edu or 717-531-5473
Psychiatry and Behavioral Health (HERSHEY)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
NCT05836051
STUDY00019883
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Inclusion Criteria:
Daily inhaled nicotine user for over 1 year
No plan to quit tobacco use in the next month
Age 21 or older
Able to read and write in English

Exclusion Criteria:
MRI Contraindications
Unstable or Significant Medical Conditions
Uncontrolled serious mental illness
Current substance abuse
Smoking, Vaping, Nicotine and Tobacco, Addiction & Substance Abuse, Mental & Behavioral Health
Prefer not to display
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Hershey, PA ,

Recruitment for Nicotine and Tobacco Related Research at Penn State Hershey

The purpose of this project is to screen potential participants for multiple research studies being conducted by tobacco researchers at Penn State Hershey. Since there are multiple IRB approved studies enrolling at Penn State Hershey with similar but not identical inclusion/exclusion criteria, it is more efficient for the researchers and participants to have one phone number to call initially for basic screening. After completing this, the participant can be redirected for more specific screening if they are found to be potentially eligible for one of the studies.

Participants will fill out a 5-minute survey on tobacco use in order to find out which study they may be eligible for.

Depends on study

Yes
 

Jonathan Foulds
Nicolle Krebs - at nkrebs@pennstatehealth.psu.edu or 844-207-6392
Public Health Sciences (HERSHEY)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00002213
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Inclusion Criteria:
Age 21 or older
Current tobacco user

Exclusion Criteria:
Age less than 21
Smoking, Vaping, Nicotine and Tobacco, Addiction & Substance Abuse, Lung Disease & Asthma
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Harrisburg, PA ,
Hershey, PA ,
York, PA ,

Penn State SELF - Student Engagement, Learning and Flourishing

Substance misuse is a leading national problem, with young adults at high risk. We aim to develop a university resource that elucidates biobehavioral underpinnings of problematic student substance use at University Park campus. This initiative would inform services needed, provide engaged learning opportunities, connect with faculty, and catalyze high-impact, interdisciplinary research. In addition to this primary rationale, this study will allow us to capture detailed information about other critical student experiences such as food and housing insecurity, experiences of discrimination, and daily health practices to prevent the transmission of COVID-19. Participants will be asked to take a baseline survey followed by a 21- daily diary protocol (brief 5 minute survey each day for 21 days. For more information or to register interest in participating please see: https://projectself.psu.edu/register-your-interest/

No
 

Stephanie Lanza
Courtney Whetzel - at projectSELF@psu.edu
Methodology Center (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00015710
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Inclusion Criteria:
Undergraduate at PSU
Enrolled at UP
18-24 years old

Exclusion Criteria:
Non-students
Part-time students
Students located in the EEA
Older than 24
No graduate students
Smoking, Vaping, Nicotine and Tobacco, COVID-19, Mental & Behavioral Health
I'm interested
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Translational Studies on Electronic Cigarette-derived Oxidants and their Long-term Cardiopulmonary Effects

This is a pilot study on the impact of switching from cigarettes to Electronic Cigarettes on disease-related clinical symptoms and biomarkers of harm in smokers with preexisting COPD

You will be asked to reduce your cigarette smoking and use study-provided e-cigarettes for 3 months. You will be asked to attend 2 in-person visits at the Hershey Medical Center and participate in 4 telephone visits. Throughout the study you will be asked to complete questionnaires, have heart rate, blood pressure and pulse oximetry taken, electrocardiograms (ECGs), height and weight measured, provide medical history, perform pulmonary function tests, complete a 6-minute walk, have your exhaled carbon monoxide measured, provide urine specimen and have blood drawn.

Yes
 

Rebecca Bascom
Timothy Sheehan - at tsheehan@pennstatehealth.psu.edu or 717-531-2925
Medicine: Pulmonary, Allergy and Critical Care (HERSHEY)
 

All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT05239793
STUDY00015514
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Inclusion Criteria:
Ages 21-74
mild-moderate COPD
current smoker

Exclusion Criteria:
actively changing smoking behavior
current use of other tobacco products
allergic to vegetable glycerin and/or propylene glycol
chronic drug and/or alcohol abuse
Smoking, Vaping, Nicotine and Tobacco, Addiction & Substance Abuse, Lung Disease & Asthma
Approved device(s)
I'm interested
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Hershey, PA ,

Examining brain responses linked to emotion in individuals who smoke cigarettes

The goal of this study is to measure emotional and brain responses related to the motivation to smoke cigarettes. The study uses a method called functional magnetic resonance imaging, or fMRI, which is a research method for measuring activity in the brain. The study also involves measuring moment-to-moment changes in emotion by coding facial expressions. A primary goal of the project is to examine how changes in brain activity are related to changes in emotion over time. If successful, the project will help to demonstrate the usefulness of combining fMRI and facial coding to study cigarette smoking and other harmful behaviors.

There will be two in-person visits. Brain imaging scans (using functional magnetic resonance imaging) will be completed at one of these visits.

100

Yes
 

Stephen Wilson
Stephen Wilson - at sjw42@psu.edu
Psychology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
NCT04310735
STUDY00011266
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Inclusion Criteria:
Between 21 and 55 years old
Must smoke cigarettes each day
Must be right handed
Must be fluent English speaker
Must be willing to abstain from smoking for 12 hours during the study

Exclusion Criteria:
Must not be actively trying to quit smoking
Must not currently have significant cardiovascular or respiratory disease
Must not be claustrophobic
Smoking, Vaping, Nicotine and Tobacco, Addiction & Substance Abuse, Cancer
Not applicable
I'm interested
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State College, PA ,

Randomized trial of low nicotine cigarettes plus electronic cigarettes in smokers

This study will examine the health effects of lowering the nicotine content in cigarettes while having access to an electronic cigarette.

There are a total of 8 study visits, 5 are in person and 3 are done virtually through a phone or computer. At the third visit you will be randomly assigned to one of two study cigarette groups AND one of two e-cigarette groups for 16 weeks. You will use the study cigarettes and e-cigarette throughout the study. During study visits you will be asked to complete questionnaires, provide urine samples, and complete other health measurements. You will record your cigarette and e-cigarette use every day.

$550

Yes
 

Jonathan Foulds
Nicolle Krebs - at nkrebs@pennstatehealth.psu.edu or 717-531-5673
Public Health Sciences (HERSHEY)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
NCT04058717
STUDY00012579
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Inclusion Criteria:
Ages 21-70
Smoke 5 or more cigarettes per day
Must be willing to both switch to a different type of cigarette and try an electronic cigarette
No serious quit attempt or use of smoking cessation medication in the past 30 days
Meet diagnostic criteria for current or lifetime mental health condition

Exclusion Criteria:
Women who are pregnant, nursing, or trying to become pregnant
Any known allergy to propylene glycol or vegetable glycerin
History of difficulty providing blood samples
Other member of the household currently participating in the study
Unstable or significant medical condition in the past 3 months
Smoking, Vaping, Nicotine and Tobacco, Addiction & Substance Abuse, Mental & Behavioral Health
I'm interested
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Hershey, PA ,

Effect of oral black raspberry administration on oral cell DNA adducts in smokers

This is an intervention study that will examine the effect of black raspberry lozenges on mouth cell DNA damage in smokers.

Following one week of being in the study you will be given black raspberry lozenges to take 5 times daily for 8 weeks. Afterwards you will participate in the study for an additional 4 weeks for a ‘wash-out’ period where no lozenges are given. During study visits you will be asked to complete questionnaires, provide a urine sample, and a mouth cell sample by brushing the inside of your cheek with a toothbrush. You will smoke as you normally do throughout the study. You will record cigarette and lozenge use every day. You will complete 2 phone call interviews about your 24-hour food intake during the beginning and the end of the study.

$380

Yes
 

Karam El-Bayoumy
Nicolle Krebs - at nkrebs@pennstatehealth.psu.edu or 717-531-5673
Biochemistry and Molecular Biology (HERSHEY)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00013621
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Inclusion Criteria:
Smokers (5 cigarettes per day or more)
21-75 years of age
No quit attempt in the prior 30 days
No plans to quit smoking in next 4 months
Willingness and ability to attend 8 visits over 13 weeks

Exclusion Criteria:
Current unstable or significant medical condition
Women who are pregnant or nursing
Use of marijuana or other illegal drugs
Any known allergy to raspberries
Heavy drinking (>4 drinks/day, 5 days/wk)
Smoking, Vaping, Nicotine and Tobacco, Food & Nutrition, Prevention
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Hershey, PA ,

Linking brain network dynamics to smoking-related behavior

Most attempts to quit smoking end in relapse, or a return to regular smoking. One of the biggest threats to cessation is a lapse (i.e., any cigarette use during a quit attempt). Thus, characterizing why lapses occur is essential to understanding and preventing smoking relapse. Functional magnetic resonance imaging (fMRI) is a promising method for characterizing the psychological processes that lead to smoking lapses because it provides a way to measures patterns of brain activity thought to reflect relevant mental processes as they change over time. However, methodological issues have hindered the ability to capitalize on this potential and prevented an understanding of how brain activity and corresponding psychological processes unfold in the critical moments that immediately precede a smoking lapse. The proposed project will address this knowledge gap using a novel fMRI paradigm adapted from a well-validated behavioral lapse task. The goals of the project are to characterize changes in brain activity that lead up to a lapse and to investigate how these changes are related to concurrent affect and subsequent cigarette use.

There will be two in-person visits, both will involve completion of computerized questionnaires and one will involve completing and MRI scan

175

Yes
 

Stephen Wilson
Stephen Wilson - at sjw42@psu.edu or 814-867-2333
Psychology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT05572671
STUDY00020857
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Inclusion Criteria:
Smoke cigarettes
Age 21-65

Exclusion Criteria:
Ineligible for MRI scan
Claustrophobic
Smoking, Vaping, Nicotine and Tobacco, Addiction & Substance Abuse, Mental & Behavioral Health
Not applicable
I'm interested
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State College, PA ,

Pilot study examining adherence to and efficacy of the quitSTART smoking cessation smartphone application

The goal of this pilot study is to collect preliminary information about the effectiveness of a smoking cessation app called quitSTART, which is a product of Smokefree.gov created by the Tobacco Control Research Branch at the National Cancer Institute. The app is available to the public for download at no cost. The aims of the project are: 1) to measure how participants respond to the app and how they use it during an attempt to quit smoking; and 2) receptivity and adherence rates to the app; 2) to examine whether participants reduce or discontinue smoking while using the app.

The study is designed to test the efficacy of a smoking cessation smartphone app and has three parts. For the first part, participants are asked to watch an orientation video about the study, fill out questionnaires, and watch a video tutorial explaining how to use a smartphone app. Then, for the second part of the study, participants are asked to use the smoking cessation app to help them with their quit attempt for 30 days. Finally, for the third part of the study, participants are asked to complete an exit survey about their experience using the app after 30 days.

$20

No
 

Stephen Wilson
Stephen Wilson - at sjw42@psu.edu
Psychology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is NOT accepting healthy volunteers
STUDY00021797
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Inclusion Criteria:
Must be 21-65 years old
Must smoke cigarettes everyday
Must own and regularly use a smartphone
Must be planning a quit attempt within the next month
Must be willing to use a smartphone app to assist them during a quit attempt

Exclusion Criteria:
Meet criteria for current dependence on a substance other than nicotine
Previously used the quitSTART smartphone app
Smoking, Vaping, Nicotine and Tobacco
Survey(s)
I'm interested
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Translational Study on Temperature and Solvent Effects on Electronic Cigarette-Derived Oxidants

Determine if free radicals produced by electronic cigarettes or conventional cigarettes impact inflammation and oxidative stress responses in users.

Subjects will come to the Clinical Research Center at Hershey and if they are a nicotine user they will bring their device (cigarette or e-cigarette) with them. Healthy volunteers will answer the same questionnaires and provide the same samples but will not use any nicotine during their visit. They will provide blood, urine and exhaled breath condensate samples. They will be videotaped using their own devices and they will answer questionnaires. This is a one-time visit that will last around 2 hours.

25

Yes
 

Thomas Spratt
smokingresearch@pennstatehealth.psu.edu
Biochemistry and Molecular Biology (HERSHEY)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00023965
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Inclusion Criteria:
21 years or older
For cigarette or e-cigarette users: No plan on quitting in the next 3 months
For e-cigarette users: E-cigarette use for more than 1 year
For cigarette users: Cigarette use for more than 1 year
For
Healthy volunteers
: No nicotine use via e-cigarette or cigarette use in the past year

Exclusion Criteria:
Respiratory diseases
Uncontrolled substance abuse
Pregnant or nursing
Smoking, Vaping, Nicotine and Tobacco, Addiction & Substance Abuse
Not applicable
I'm interested
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Study Locations

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Hershey, PA ,