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Search Results Within Category "Children's Health"

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42 Study Matches

Prevalence of Avoidant Restrictive Food Intake Disorder (ARFID) traits among children and adolescents with Food Allergy

This study looks at understanding eating behaviors and attitudes toward food in children/adolescents. More specifically the study's goal is to compare those with and without food allergies to gain a better understanding of a possible underlying factor towards certain behaviors. Children and their caregivers will complete a survey composed of a short section on the child's medical history regarding allergies followed with questions in commonly used clinical assessments.

No
 

Jodi Brady-Olympia
Jodi Brady-Olympia - at jbradyolympia@pennstatehealth.psu.edu or 717-531-1383
Pediatrics: General Pediatrics (HERSHEY)
 

All
Younger than 18 years old
This study is also accepting healthy volunteers
STUDY00015831
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Inclusion Criteria:
Ages 8-17

Exclusion Criteria:
Age under 8 years old
Age 18 years or older
Intellectual disability preventing comprehension of questions
Child and/or caregiver unable to respond to English-language questionnaire
Children's Health, Allergies, Food & Nutrition
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Attention and Emotional Development in Children

Children with attention problems often feel anxious or worried, and likewise, children who are anxious or worried often have problems with attention. We are looking for children aged 8-12 who may or may not have problems with attention or anxiety to help us understand what happens in the brain that could explain why. You will receive up to $100 gift card for your participation, and informal clinical feedback on your child.

Two in person visits of 2 hours each to the University Park campus, scheduled at the participant(s) convenience

$100

Yes
 

Cynthia Huang-Pollock
Christina Hlutkowsky - at ChildAttention@psu.edu or 814-863-0250
Psychology (UNIVERSITY PARK)
 

All
All
This study is also accepting healthy volunteers
STUDY00005954
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Inclusion Criteria:
Children aged 8-12

Exclusion Criteria:
Children outside of the 8-12 age range
History of seizures or photosensitive epilepsy
Children's Health, Mental & Behavioral Health
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Altoona, PA ,
State College, PA ,

Parent-to-child anxiety transmission in early childhood: Capturing in-the-moment mechanisms through emotion modeling and biological synchrony

Anxiety can emerge as early as pre-school age (4-6) and is often linked to anxiety in the parent. This study will examine patterns of brain and behavioral synchrony in parent-child pairs as they complete puzzles together and other social activities.

This is a longitudinal study examining the role that parent-child synchrony and emotional modeling plays in the transmission of anxiety. Participants will complete yearly laboratory visits and 6-month follow-up visits. The yearly laboratory visits (V1,3,5) will include a battery of tasks and questionnaires, but the six-month follow-up visits(V2,4) will only include online questionnaires. Participants at both Penn State and Washington University, St. Louis will follow the same procedures.

Participating families will be given $100 at each of V1 and V3, $25 for each of the follow-ups at V2 and V4, $100 and a $50 completion bonus at V5, for a total amount of $400.

Yes
 

Koraly Perez-Edgar
Harmony Nguyen - at harmony@psu.edu or 814-867-2322
Psychology (UNIVERSITY PARK)
 

All
All
This study is also accepting healthy volunteers
STUDY00019415
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Inclusion Criteria:
Families with children between the ages of 4 and 6
Children without serious medical issues or complications
Parents or caregivers aged 18 or older

Exclusion Criteria:
Families that cannot communicate in either English, Spanish, or a language with an available translator
Children diagnosed with any neurological disorders and/or diseases
Children unable to communicate at a level similar to their peers
Children that have experienced a head injury with a loss of consciousness
Children 0 to 3 years of age; Children 7 and older
Children's Health, Mental & Behavioral Health
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State College, PA ,

Caregiver's Perceptions of High-quality Early Education and Care

This is an exploratory study which looks at how caregivers define high-quality early education and care. Participants will fill out a questionnaire containing open-ended and closed-ended questions. It will take participants no longer than 20 minutes to complete.

No
 

Hannah Mudrick
Hannah Mudrick - at hxm99@psu.edu
Behavioral Sciences and Education (HARRISBURG)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00011162
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Inclusion Criteria:
Adults age 18 and older
Adults who are fluent in English
Adults who are regular caregivers of children between birth and age 5
Individuals who can read and respond to written close- and open-ended survey questions electronically
Individuals who live in the United States

Exclusion Criteria:
Individuals under the age of 18
Individuals who are not fluent in English
Individuals who are not regular caregivers of children between birth and age 5
Individuals with poor reading comprehension and are otherwise limited in their ability to read and respond to survey questions
Individuals who do not currently live in the United States of America
Children's Health, Education, Mental & Behavioral Health
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PEDS-PLAN – Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

A study of the safety and feasibility of using molecularly guided therapy in combination with standard therapy followed by maintenance therapy with DFMO in patients with newly diagnosed high risk neuroblastoma.

Participating in this study requires that you visit the study hospital Penn State Hershey Medical Center multiple times over the course of the full study for evaluations (physical exam, blood draw, urine analysis, etc.) and scans (MRI/CT, MIBG). Weekly visits may occur at your home institution with your home treating oncologist. As a subject in this clinical trial you are expected to receive treatment on this phase of the study for a total of about 2 ½ years if you complete all portions. After treatment, you will have follow-up examinations and medical tests.

Yes
 

Valerie Brown
Suzanne Treadway, MS, RN, CCRP - at streadway@pennstatehealth.psu.edu or 717-531-3097
Pediatrics: Hematology/Oncology (HERSHEY)
 

All
All
This study is NOT accepting healthy volunteers
NCT02559778
STUDY00003478
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Inclusion Criteria:
A confirmed diagnosis of neuroblastoma.
Must be 21 years of age or younger when diagnosed.
No prior systemic therapy with some exceptions.
Tumor samples will be obtained only in a non-significant risk manner and not solely for the purpose of the study.

Exclusion Criteria:
Receiving another study drug while on this study.
Female patients who are lactating are not eligible unless they agree not toe breast feed.
Children's Health, Cancer
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Hershey, PA ,

The Penn State Personalized Research for Innovation, Discovery, and Education (PRIDE) Program.

The Penn State Personalized Research for Innovation, Discovery, and Education (PRIDE) Program.The aims of the PRIDE Program are to:1. Create a centralized Biorepository using extra blood obtained from a clinically-ordered, or another IRB approved research protocol initiated blood draw, leftover biospecimens that are removed during medically indicated procedures or a saliva sample from consented participants that do not have clinically ordered blood draws or a medical procedure.2. Construct a dynamic database of health and related data (via both manual and electronic abstraction) from consented participants.3. Establish a mechanism for approving use of the banked biospecimens for future research.

The participant will meet with PRIDE Program team member in person to join the study.The participant with supply a saliva sample for the program.There is no compensation for joining the PRIDE Program.

Yes
 

James Broach
Molly Pells - at IPM@pennstatehealth.psu.edu or 855-369-3540
Biochemistry and Molecular Biology (HERSHEY)
 

All
All
This study is also accepting healthy volunteers
PRAMS00040532
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Inclusion Criteria:
Any age
Ability of patient, child and/or parent to understand or complete the consent process

Exclusion Criteria:
Unable to understand or complete the consent process
Men's Health, Children's Health, Women's Health
Not applicable
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Hershey, PA ,

The HEALthy Brain and Child Development Study (HBCD)

This multi-site consortium research study, entitled the HEALthy Brain and Child Development (HBCD) study, willprospectively examine human brain, cognitive, behavioral, social, and emotional development beginning prenatallythrough age 10 years. The study will determine the short- and long-term impacts of a variety of potentially harmfulas well as protective environmental factors. These include prenatal substance use, mental health, stress,sociodemographics, biological and genetic factors, and parent/child interaction. The overall goal of this study is tounderstand the neurodevelopmental trajectories of children growing up in diverse environments. A sample of~7,500 pregnant women will be recruited from 25 sites across the U.S. and they and their liveborn children will befollowed for 10 years.

If you agree for you and your child to participate, we will ask you to take part in completing visits from pregnancy through the first 10 years of your child’s life. These visits will take place both in-person and remotely. The length of visits will vary and may last between approximately one to nine hours per visit (which can be broken up into multiple visits). Over the first four years of the study, all study visits will require about 33-37 hours total. This will include interviews, questionnaires and other tests about yourself and your child. We will ask you and your child to wear small devices for a few days to measure heart rate and or movement. We will ask you and your child to provide some biological samples. Because this study is looking at how a child’s brain develops in the first years of life, we will ask that you allow your child to have brain scans and other measures of how your child’s brain is developing. This study is being offered in both State College, PA at the University Park campus and in Hershey, PA at the College of Medicine campus. You may choose to complete this study at either site.

$1,350

Yes
 

Koraly Perez-Edgar
hbcd@psu.edu; hbcd@pennstatehealth.psu.edu 814-863-6018
Psychology (UNIVERSITY PARK)
 

All
All
This study is also accepting healthy volunteers
SITE00001129
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Inclusion Criteria:
Pregnant or recently gave birth
Speaks English or Spanish

Exclusion Criteria:
Is not pregnant or does not have newborn
Does not speak English or Spanish
Children's Health, Pregnancy & Infertility, Women's Health
Not applicable
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Study Locations

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Hershey, PA ,
State College, PA ,

Sleep and eating behaviors in rural preadolescent children (Tween SPACE [Sleep Patterns, Appetite Control, and Environment])

The goal of this study is to learn about how children's sleep is related to their eating behaviors the next day. We are also interested in learning about factors that relate to eating behaviors and sleep health that are specific to preadolescent children living in rural communities. Participants will complete two virtual study visits via Zoom, answer surveys, and wear sleep and physical activity monitors for 2 weeks in their own homes.

- Study materials will be mailed to participants- Parent and child will attend a Zoom visit with a researcher to go over study procedures and measure child's height and weight- Child will wear a sleep monitor on their wrist and physical activity monitor around their waist continuously for 14 days- Child will attend a second Zoom visit to complete questionnaires- Parent will complete an online survey- Participants will return study materials via provided, prepaid shipping packaging

$200

No
 

Emily Hohman
Emily Hohman - at tweenspace@psu.edu or 814-865-5245
Center for Childhood Obesity Research (UNIVERSITY PARK)
 

All
Younger than 18 years old
This study is also accepting healthy volunteers
STUDY00020663
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Inclusion Criteria:
Children age 8-12
Living in a rural zip code in United States (as defined by Health Resources & Services Administration)
Child BMI-for-age >=85th percentile OR BMI-for-age >=15th percentile plus one biological parent with overweight
Able to read and answer questions in English

Exclusion Criteria:
Medical conditions that significantly impact eating, sleep or growth (e.g. eating disorder)
Unable to connect to Zoom session via internet or cell-phone data
Unable to receive and sign for package with study supplies
Parent/child living in the same household as a previous or current participant in the study
Children's Health, Food & Nutrition, Sleep Management
Not applicable
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Pennsylvania Adoptees Longitudinal Study (PALS)

This study will examine various factors within the home of children adopted from the child welfare system between the ages of 4 and 10 that may impact their development. The first visit will occur remotely via Penn State Health Microsoft Teams; the second visit is optional and will occur within 4 weeks of the first visit at the Transforming Lives of Children Center in Harrisburg, PA; and the third visit will occur one year after the first visit, when research staff will travel to participants' homes. This research will help understand the factors that impact the development of children adopted from the child welfare system and how we may better serve these children and their families.

The child and parent will be asked to complete interviews, questionnaires and various tasks. Parents may also be asked to complete questionnaires online.Participation will last for one year and include the following:-One visit occurring remotely via PSH Microsoft Teams-One visit at the Transforming the Lives of Children Center in Harrisburg, PA, four weeks after Zoom visit (optional)-Final visit at home will occur one year after the first Zoom visit

$225

Yes
 

Brian Allen
pals@pennstatehealth.psu.edu 717-531-0003, ext=321713
Pediatrics: Child Abuse (HERSHEY)
 

All
All
This study is also accepting healthy volunteers
STUDY00013344
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Inclusion Criteria:
Child age between 4 and 10
Child legally adopted by the caregiver
The same caregiver will participate in each of the visits

Exclusion Criteria:
Child diagnosed with intellectual disability
A biological parent resides in the same home as the child
Children's Health, Mental & Behavioral Health
I'm interested
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Study Locations

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Location Contacts
Altoona, PA ,
Carlisle, PA ,
DuBois, PA ,
Erie, PA ,
Greater Philadelphia Area, PA ,
Greater Pittsburgh Area, PA ,
Harrisburg, PA ,
Hazleton, PA ,
Hershey, PA ,
Mont Alto, PA ,
Reading, PA ,
Schuylkill Haven, PA ,
Sharon, PA ,
State College, PA ,
Wilkes-Barre/Scranton Area, PA ,
Williamsport, PA ,
York, PA ,

Characterizing resilience to food-cue induced overeating in children

This is a behavioral and neuroimaging study that will examine how food commercials affect the way a child eats and responds to food. Children enrolled in the study will complete 5 in-lab sessions that include eating meals and snacks, watching TV, and playing computer games. For one of these sessions, children will complete an fMRI scan. On the first and last visit to the lab, children will receive a DXA scan to assess their body composition.

We are looking for children to help us learn about how kids respond to different types of foods and food advertisements. The study consists of 5 visits to our facilities in Noll and Chandlee Labs, located on the University Park Campus. For 3 visits your child will eat test meals and snack buffets in our laboratory. On 1 visit we will use fMRI to take pictures of your child’s brain. We will use a DXA to scan for lean muscle and conduct an IQ test. These procedures are not harmful. You and your child will fill out questionnaires.Your child will also play computer games and watch commercials.

$250.00-450.00

Yes
 

Kathleen Keller
Jonathan Bauman - at jmb7118@psu.edu or 814-865-9841
Nutritional Sciences (UNIVERSITY PARK)
 

All
Younger than 18 years old
This study is also accepting healthy volunteers
NCT05073185
STUDY00015835
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Inclusion Criteria:
In order to be enrolled, children must be of good health based on parental self-report.
Be 7-9 years-old at enrollment.
Not be taking any medications known to influence body weight, taste, food intake, behavior, or blood flow.
Have no learning disabilities (e.g., ADHD).
The biological mother must have a body mass index either between 18.5 - 25 kg/m2 (low-risk group) or greater than or equal to 30 kg/m2 (high-risk group).

Exclusion Criteria:
They are not within the age requirements (< than 7 years old or > than 9 years-old at baseline).
If they have a learning disability, ADD/ADHD, language delays, autism or other neurological or psychological conditions.
If they have a pre-existing medical condition such as diabetes, rheumatoid arthritis, Cushing’s syndrome, Down’s syndrome, severe lactose intolerance, Prader-Willi syndrome, HIV, cancer, renal failure, cerebral palsy, or can't engage in moderate exercise.
If they don’t speak English.
Biological mother must have a body mass index either between 18.5 - 25 kg/m2 (low-risk group) or greater than or equal to 30 kg/m2 for mothers (high-risk group), or they are excluded.
Children's Health, Food & Nutrition, Prevention
Not applicable
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Study Locations

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State College, PA ,

Expanding Family Foundations to 2nd-Time Parenthood - Focus Group

This focus group study, funded by Penn State's Social Science Research Institute, brings together couples with preschool-aged firstborns who are pregnant with their 2nd child or who have given birth to their 2nd child within the last 12 months. Couples will be interviewed about how they worked together as a team (as coparents) to prepare their firstborn for the birth of the second child and to prepare themselves for 2nd-time parenthood.

Yes
 

Douglas Teti
Douglas Teti - at dmt16@psu.edu or 814-863-9570
Human Development and Family Studies (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00015968
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Inclusion Criteria:
1.Two-caregiver families, any race or ethnicity, with one or two children: a.One subgroup with one child < 6 years of age and pregnant with a 2nd child b.One subgroup with one child < 6 years of age and an infant between 1-to-12 months of age.
2.Each caregiver is over 18 years of age.
3.Caregivers are living together in the same household and are either married or living with a partner.
4.Families living independent of parents’ families of origin.
5.Both caregivers fluent in communicating in English.

Exclusion Criteria:
1.One or the other caregiver cannot understand or speak English
2.Caregivers are under 18 years of age.
3.Caregivers not living together
4.Caregivers not living independently of their families of origin
5.Single-parent families with no live-in partner.
Children's Health, Prevention, Mental & Behavioral Health
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Study Locations

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Location Contacts
Altoona, PA ,
Carlisle, PA ,
DuBois, PA ,
Erie, PA ,
Greater Philadelphia Area, PA ,
Greater Pittsburgh Area, PA ,
Harrisburg, PA ,
Hazleton, PA ,
Hershey, PA ,
Mont Alto, PA ,
Reading, PA ,
Schuylkill Haven, PA ,
Sharon, PA ,
State College, PA ,
Wilkes-Barre/Scranton Area, PA ,
Williamsport, PA ,
York, PA ,

The Child Health Study

We want to understand how a child's environment affects biology in ways that impact child health

The project involves completing three Penn State ChildHealth Days on the University Park Campus in StateCollege, PA 2 years apart. Your child will receive a comprehensivehealth screening and you will be asked to completeseveral assessments about your child’s physical healthand emotional well-being. Travel and hotel costs arefree for eligible families.

520

Yes
 

Hannah Schreier
Finnley Christine - at childhealthstudy@psu.edu or 888-924-4535
Biobehavioral Health (UNIVERSITY PARK)
 

All
Younger than 18 years old
This study is also accepting healthy volunteers
STUDY00006550
Show full eligibility criteria
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Inclusion Criteria:
Children 8-13 years of age
Speak and understand English
Participation of a legal guardian

Exclusion Criteria:
Intellectual or learning disability
Children's Health, Food & Nutrition, Education
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Study Locations

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State College, PA ,

Development of Adolescent and Young Adult Social Health (DASH)

Adolescence is a unique developmental period that prepares individuals for adulthood. We are studying the behavioral and brain basis of this important time, particularly in terms of how adolescents understand and think about other people. To study this important developmental transition, we are inviting typically developing children (6-8 yrs), adolescents (10-14 yrs), and young adults (18-22 yrs) to help us with this study. Participants answer questionnaires, play games of face recognition, and have pictures of their brains taken in a neuroimaging session. Child and adolescent participants also have physical exams. Volunteers are compensated for time (between $185-630) in the lab and for the neuroimaging session.If you are a parent and want to begin the screening process for you child, please go here https://pennstate.qualtrics.com/jfe/form/SV_51lN8sODiukYOONIf you are an adult, and want to begin the screening process please go here:https://pennstate.qualtrics.com/jfe/form/SV_5cXMng6ybKe0WwJ

Participants answer questionnaires, play games of face recognition, and have pictures of their brains taken in a neuroimaging session. Child and adolescent participants also have physical exams. This study requires multiple in-person visits.

between $185-630

Yes
 

Suzy Scherf
Dr. Suzy Scherf - at suzyscherf@psu.edu or 814-954-0112
Psychology (UNIVERSITY PARK)
 

All
All
This study is also accepting healthy volunteers
STUDY00007212
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Inclusion Criteria:
Native English speaker
Normal vision and hearing (with correction)
Free of neuroneurologic, psychiatric, endocrinology disorders
Free of concussions with loss of consciousness

Exclusion Criteria:
Family history of autism spectrum disorders (in parents or full siblings)
History of working with metal
Irremovable metallic implants in the body (e.g. braces)
Pregnancy
Weigh more than 250lbs or get claustrophobic in small spaces
Children's Health, Education, Mental & Behavioral Health
Not applicable
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State College, PA ,

Neurophysiological Markers of Pediatric Irritability and its Response to Intervention

This study uses specific computer tasks to predict irritability in children with Attention Deficit/Hyperactivity Disorder (ADHD), as well as the effect of ADHD medication (stimulants) on irritability symptoms in children with ADHD. Children ages between the ages of 5 and 12 years are eligible and must have an established diagnosis of ADHD or suspected symptoms of ADHD.

Yes
 

Raman Baweja
Vanessa Cao - at vcao@pennstatehealth.psu.edu or 717-531-0003, ext=285966
Psychiatry and Behavioral Health (HERSHEY)
 

All
Younger than 18 years old
This study is NOT accepting healthy volunteers
NCT03279952
STUDY00008087
Show full eligibility criteria
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Inclusion Criteria:
Children between the ages of 5 and 12
Children diagnosed with ADHD or suspected ADHD Symptoms
Children who are able to stop ADHD medication for testing days
Parent/child fluent in English

Exclusion Criteria:
Children younger than 5 year or older than 12 years
Children with visual or hearing deficits or sensitivity to loud noise
Neurological conditions such as active seizure disorder
Prominent traits or diagnosis of Autism, marked developmental delay, mania, psychoses, or suicidal ideation.
Children's Health, Mental & Behavioral Health
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See this study on ClinicalTrials.gov
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Study Locations

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Location Contacts
Hershey, PA ,

Validation and Feasibility of In-Home Child Height Measurement using a Portable Ultrasound Stadiometer

The goal if this study is to determine if a new tool (PUSH stadiometer) can be used by parents to accurately and easily measure children's height in their home.

Participants will be required to attend 1 Zoom visit and 1 in-person visit on Penn State's University Park Campus. Each of these visits will last 30 minutes or less.During the Zoom visit, a researcher will help parents use a new tool (PUSH Stadiometer) to measure their child's height in their home.At the in-person visit, a researcher will measure the child's height and weight, and parents will complete a short survey.

20

Yes
 

Emily Hohman
Emily Hohman - at eeh12@psu.edu or 814-865-5245
Center for Childhood Obesity Research (UNIVERSITY PARK)
 

All
All
This study is also accepting healthy volunteers
STUDY00020741
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Inclusion Criteria:
Child age 3-18 years
Parent age 18 years or older
Able to connect to a Zoom session from home
Able to read and answer questions in English

Exclusion Criteria:
Child has a medical condition that interferes with standing upright (e.g., paralysis, severe scoliosis)
Children's Health, Prevention
Survey(s)
I'm interested
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State College, PA ,

Insulitis, Inflammation, Dietary intake and Omega-3 Biostatus of Youth with Partial Remission of Type 1 Diabetes

Only 50% of patients with type 1 diabetes (T1D) recover insulin secretion function after 3 months of initial diagnosis, and this phase is called partial remission (PR) of T1D, also called "Honeymoon phase". During this PR phase of T1D, patients recover the ability to secrete more than 50% of their insulin secretion function. This phase of PR typically lasts no longer than 6 or up to12 months, and has been frequently defined as requiring exogenous insulin below 0.5 units per kilogram per day, and hemoglobin A1C is typically below 7.5%. Most recently the use of a coefficient called IDAA1C ≤ 9 has became more accepted as the methodology to determine the development of partial clinical remission of T1D (honeymoon phase). Prior data published by the SEARCH study (national epidemiological study) showed that youth with prolonged honeymoon phase had higher intake of omega -3 fatty acids, vitamin D intake and leucine intake than those youth without prolonged honeymoon phase of T1D. Currently, there are not approved medications to prolong this phase of partial remission of type 1 diabetes, however inducing PR in youth with T1D could potentially decrease the risk of multi-organ damage caused by chronic severe hyperglycemia associated to the chronic hyperglycemia related to T1D.We aim to perform a case- multiple control study between youth with prolonged partial remission phase of T1D after one year of diagnosis, and compare these youths with multiple controls matched by age, gender, race, and puberty stage to study the potential protective factors associated to the development of prolonged partial remission of T1D.

Participants will be approached at their routine Pediatric diabetes clinic appointment. If participants agrees to be in the research, informed consent/assent will be reviewed and signed by all parties. Participant's parent/guardian will be asked to complete a questionnaire. The participant's glucose machine/insulin pump will be downloaded for study purposes. Participant will undergo a fingerstick and a blood draw to collect specific lab values as outlined in the consent.

$35.00

Yes
 

Lina Huerta-Saenz
Erica Miller - at emiller25@pennstatehealth.psu.edu or 717-531-5656
Pediatrics: Endocrinology (HERSHEY)
 

All
Younger than 18 years old
This study is NOT accepting healthy volunteers
STUDY00014114
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Inclusion Criteria:
Type 1 diabetes diagnosis for more than one year
Age 1-17 years old, any gender
Attendance to the Pediatric diabetes clinic at Penn State Health in Hershey, PA
Most recent hemoglobin A1C below 7.5%

Exclusion Criteria:
Age older than 17 years old
History of seafood allergies and/or milk/dairy related allergies
Medical conditions (such as severe cerebral palsy, etc.) that could make patients unable to communicate with the study team
Existence of other autoimmune diseases in addition to T1D requiring regular treatment with immunosuppressive or anti-inflammatory treatment
Diagnosis of type 2 diabetes, monogenic diabetes (MODY), secondary diabetes, pregnancy, compromised kidney function, or liver diseases
Children's Health, Food & Nutrition, Diabetes & Hormones
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Study Locations

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Location Contacts
Carlisle, PA ,
Harrisburg, PA ,
Hershey, PA ,

Decision-Making in ADHD: An Evaluation of the Subjective Value of Rewards and Costs

Children with attention and behavior problems often need external rewards to motivate them to perform challenging tasks, but we don’t yet know much about how children weigh potential rewards and the effort required to obtain the rewards. This research is being done to find out how children with varying levels of ADHD symptoms value rewards and costs when making decisions about whether or not to perform a difficult task.

There will be one in-person visit. Children will complete two computerized cognitive tasks (thinking games), and will be able to earn prizes from the points they earn on these tasks. Parents will also be asked to complete a few questionnaires that should take about 25 minutes to finish. Children can earn up to $50 in compensation for completing the study.

$50

Yes
 

Dan Waschbusch
Hunter Weidlich - at abc@pennstatehealth.psu.edu or 717-531-0003, ext=285969
Psychiatry and Behavioral Health (HERSHEY)
 

All
Younger than 18 years old
This study is also accepting healthy volunteers
STUDY00018076
Show full eligibility criteria
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Inclusion Criteria:
Children ages 8 to 12 years old
Children with normal or corrected vision
Caregiver and child must be fluent in written and spoken English
Willing to stop stimulant medications, when appropriate, for research testing

Exclusion Criteria:
Children who are younger than 8 years of age and children who are older than 12 years of age.
Current or past diagnosis of autism spectrum disorder, schizophrenia or other psychotic disorders.
Current use of non-stimulant medication due to its extended washout period.
Physical disabilities that are incompatible with completing laboratory tasks such as hearing impairments, or visual impairments that cannot be corrected with visual aids (i.e., glasses, contacts).
Children's Health, Mental & Behavioral Health
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Location Contacts
Hershey, PA ,

Examining Maternal Reward Responsiveness and the Intergenerational Risk for Depression

Children of depressed mothers are at high risk for developing depression, particularly as youth age into adolescence, yet relatively little is known about the mechanism underlying risk for depression in youth with depressed mothers. The present study examines maternal reward responsiveness, measured across neurophysiological, behavioral, and self-report measures as a marker of depression in mothers of adolescents. Associations between maternal reward responsiveness and parenting difficulties often associated with maternal depression, as well as adolescent functioning will be examined, to explore the clinical impact of maternal reward responsiveness on the intergenerational transmission of depression.

Yes
 

Dahlia Mukherjee
Sarah Shahriar - at sshahriar1@pennstatehealth.psu.edu or 717-531-0003, ext=285189
Psychiatry and Behavioral Health (HERSHEY)
 

All
All
This study is also accepting healthy volunteers
STUDY00009643
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Inclusion Criteria:
Female adults 18 years and above with an adolescent child aged 13-16 years
Capacity for informed consent
Fluent in verbal and written English
Adolescent between the ages of 13 and 16 years (inclusive)

Exclusion Criteria:
Diagnosis of autism spectrum disorder, substance use disorders, schizophrenia or other psychotic disorder
Any hearing or visual impairments
Investigator discretion regarding ability to participate in the study
Children's Health, Mental & Behavioral Health, Women's Health
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Hershey, PA ,

Investigating the impact of food form on children’s ability to compensate for energy

This study is looking at how different apple products (apple juice, apple sauce, and apple slices) might affect children's hunger and fullness. During 5 visits to our laboratory at Penn State, children will participate in a variety of games and tasks, and will eat meals and snacks with a research assistant. Children must be between the ages of 4.5-6 years old to participate in this study.

There will be 5 in-person visits. During each visit, children will consume an apple-based snack (apple slices, apple sauce, or apple juice) before a meal. Children will also wear a small heart rate monitor during each visit. On each visit, different games and tasks will be completed with the children while the parent completes various surveys.

$200-400

Yes
 

Kathleen Keller
Benjamin Baney - at bab349@psu.edu or 814-883-8523
Nutritional Sciences (UNIVERSITY PARK)
 

All
Younger than 18 years old
This study is also accepting healthy volunteers
STUDY00013957
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Inclusion Criteria:
Between age of 4.5-6.0 years-old
No food allergies

Exclusion Criteria:
Taking medication that can affect taste or appetite
Children's Health, Food & Nutrition
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State College, PA ,

Biologic and Environmental Impacts on Neurodevelopment and Growth (BEING)

Examine associations between biologic factors (genetic, epigenetic, transcriptomic, metabolomic) and environmental factors (family psychosocial dynamics, environmental allergens, diet, microbiome) in developing children, and their relationship with health and disease over the lifespan.

Depending on the age your child is when they are enrolled into the study will determine their designated enrollment group (Cohort 1, Cohort 2, Cohort 3, or Cohort 4) to determine how many study visits are required to complete participation in the study.For Cohort 1 participants (for infants enrolled at age 5-50 days):-11 study visits total -Each study visit includes surveys that assess your child's growth and development that you can complete via your email-Each study visit includes at minimum a saliva swab sample**Infants will be asked to collect a stool sample for 3 study visits-Optional mother participant for breast-feeding mothers who will agree to provide a small breast milk sample for 3 study visits.For Cohort 2 participants (for children enrolled at age ~24 months):-8 study visits total -Each study visit includes surveys that assess your child's growth and development that you can complete via your email-Each study visit includes a saliva swab sample**Children will be asked to collect a stool sample for 1 study visitFor Cohort 3 participants (for children enrolled at age 5-7 years):-5 study visits total -Each study visit includes surveys that assess your child's growth and development that you can complete via your email-Each study visit includes a saliva swab sampleFor Cohort 4 participants (for children enrolled at age 12-14 years):-2 study visits total -Each study visit includes surveys that assess your child's growth and development that you can complete via your email-Each study visit includes a saliva swab sample

30-100

No
 

Steven Hicks
Alexandra Confair - at aconfair1@pennstatehealth.psu.edu or 717-531-0003, ext=323206
Pediatrics: General Pediatrics (HERSHEY)
 

All
Younger than 18 years old
This study is also accepting healthy volunteers
STUDY00014022
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Inclusion Criteria:
Child participant under 18 years old
Fluent in spoken/written English
Parent or legal guardian 18+ years old
Child ages: 5-50 days old, 2 years old, 5-7 years old, and 12-14 years old

Exclusion Criteria:
Wards of the state
Non-english speaking
Parent or legal guardian with decisional impairment
Children's Health
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Parent-to-child anxiety transmission in early childhood: Capturing in-the-moment mechanisms through emotion modeling and biological synchrony

Anxiety can emerge as early as pre-school age (4-7) and is often linked to anxiety in the parent. This study will examine patterns of brain and behavioral synchrony in parent-child pairs as they complete puzzles together and other social activities.

Participation requires three steps; a remote video session with the primary parent, an in-lab visit scheduled with the primary parent and child, and then an additional set of questionnaires given to the secondary caregiver.The remote session consists of obtaining consent, 2 questionnaires, and a clinical interview. The in-lab visit typically lasts about 2-3 hours, consisting of two parent-child activities and several child-only activities. Participants will be asked to wear mobile eye-tracking glasses and special caps used to measures brain activity during some of the tasks.

$125, $100 for the primary parent/or child and $25 for secondary parent

Yes
 

Koraly Perez-Edgar
Dakota Reis - at drr5484@psu.edu or 814-867-2322
Psychology (UNIVERSITY PARK)
 

All
All
This study is also accepting healthy volunteers
STUDY00017857
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Inclusion Criteria:
Parents/Caregivers over 18
Children ages 4 to 6

Exclusion Criteria:
major medical illness
Children less than age 4 or over age 6
Children's Health, Mental & Behavioral Health
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State College, PA ,

Interoception, the 8th Sensory System, Is it measurable?

Sensory processing is often affected in children and adolescents with ASD (autism). The 8th sensory system, coined interoception, is under studied in how it affects children with autism. Our study will compare children with and without autism (ages 11-18 years) using a tool we are developing. Our study hopes to develop psychometric properties of a tool to measure this new sensory sense.

No
 

Cheryl Tierney
Cheryl Tierney - at ctierney@pennstatehealth.psu.edu or 717-531-8414
Pediatrics: General Pediatrics (HERSHEY)
 

All
All
This study is also accepting healthy volunteers
STUDY00004312
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Inclusion Criteria:
Ages 11-18
Reading at 5th grade level in English
Healthy controls OR high functioning Autism

Exclusion Criteria:
Unable to read at 5th grade reading level
Under age 11 or over age 18
Cannot read English
Children's Health, Mental & Behavioral Health
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Strong Foundations: Intervening to Promote Co-Parenting and Reduce Father Hazardous Drinking in Expectant Parents.

This is a randomized efficacy trial of a family and alcohol intervention (mFF+) for expecting couples with heavy drinking fathers and light drinking/abstaining (in pregnancy) mothers. We propose to test an innovative preventive strategy by adapting an evidence-based preventive intervention for couples at the transition to parenthood - Family Foundations (FF) - to yield a multi-modal intervention that incorporates alcohol content into existing modules of FF and adding alcohol screening and brief intervention (SBI) for hazardous drinking. This is a multi-PI application with Drs. Eiden (at Penn State) and Godleski (at Rochester Institute of Technology) as co-PIs. Dr. Colder (at the University at Buffalo (UB)) is a co-investigator and will serve as PI of the UB subcontract. Families will be recruited in Western New York (Buffalo and Rochester). Investigators at Penn State (Drs. Eiden and Feinberg) will provide training and supervision. Data management and analyses will occur at Penn State

Couples will be asked to participate in online parenting classes and family assessments during and after pregnancy. There are 3-5 prenatal and 1-4 postnatal classes that take place over Zoom. Family are also asked tp participate in 3 family assessments: 1 during pregnancy, 1 at 6 months of infant age, and one at 12 months of infant age. Families will be asked to complete inline surveys before each assessment. Additionally, families are asked to submit hair and saliva samples.

425.00

No
 

Rina Eiden
Rebecca Lim - at becca.lim@psu.edu or 814-865-6902
Psychology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
NCT04441307
SITE00000607
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Inclusion Criteria:
Pregnant/Expecting Couples
First time parents
18 years of age or above
English speaking
Both parents living together

Exclusion Criteria:
Below 18 years of age
Not pregnant with first child
Parents not living together
Children's Health, Pregnancy & Infertility, Women's Health
Survey(s)
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NMTT- Neuroblastoma Maintenance Therapy Trial Using Difluoromethylornithine (DFMO)

A study of DFMO for patients with neuroblastoma in remission.

Participating in this study requires that you visit the Penn State health Medical Center multiple times over the course of the full study for evaluations (physical exam, blood draw, urine analysis, etc.) and scans (MRI/CT, MIBG).If you agree to take part, you will receive treatment on this study for about 2 years and will be followed for survival for 5 years after the last dose of study drug. You will be asked to return to the research site approximately 15 times.

Yes
 

Valerie Brown
Suzanne Treadway, MS, RN, CCRP - at streadway@pennstatehealth.psu.edu or 717-531-3097
Pediatrics: Hematology/Oncology (HERSHEY)
 

All
All
This study is NOT accepting healthy volunteers
NCT02679144
STUDY00004295
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Inclusion Criteria:
A confirmed diagnosis of neuroblastoma.
Must be in complete remission (CR).
Tests and scans will be required to confirm remission.

Exclusion Criteria:
Patients below the defined minimum of height and weight.
Patients who are currently receiving another study drug may not participate.
Patients who are currently receiving other anticancer agents may not participate.
Children's Health, Cancer
Prefer not to display
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Hershey, PA ,

Attitudes and ethical concerns toward use of TMS in depressed adolescents: a qualitative study of recipients and their parents

This project will examine adolescents', parents'/guardians', and society's attitudes toward the use of repetitive transcranial magnetic stimulation (rTMS) and theta burst stimulation (TBS) in adolescent depression. The attitudes and concerns of adolescents,their parents/guardians, and society around TMS are important as they can influence the uptake of the interventions, with adolescents playing an important role in assenting to the intervention, and parents/guardians consenting to treatment.

Participation will involve about 1 hour of your time in a semi-structured interview. We will have a separate 1 hour semi-structure interview with your child. The interviews will take place via Zoom or phone. Interviews will be recorded. Phone calls to Zoom meetings are encouraged, if phone calls are the preferred interview method.

$50.00

No
 

Laura Cabrera
Patricia Henegan - at plh5212@psu.edu or 814-863-2092
Engineering Science and Mechanics (UNIVERSITY PARK)
 

All
All
This study is also accepting healthy volunteers
STUDY00020208
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Inclusion Criteria:
Adolescents between 12-17 years old with the ability to assent
Adults with the capacity to consent
Able to conduct the interview in English

Exclusion Criteria:
Children below 12 years old
Children who lack the capacity to assent
Adults who llack the capacity to consent
Children's Health, Mental & Behavioral Health
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Emotion Regulation and Mother-Infant Synchrony

The aim of this study is to better understand emotion regulation in infants by measuring brain, behavior, and mother-infant relational mechanisms. We plan to collect simultaneous brain activation in mothers and infants while they engage in a face-to-face interaction. We will then test associations between individual brain activation, mother-infant brain synchrony, and infant emotion regulation behaviors.

Participants complete questionnaires online, then come in for 1 in-person visit. Mother and baby complete a play and a neutral task while fNIRS is collected from them simultaneously.

40

Yes
 

Berenice Anaya
Berenice Anaya - at bua25@psu.edu
Psychology (UNIVERSITY PARK)
 

All
All
This study is also accepting healthy volunteers
STUDY00018109
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Inclusion Criteria:
Infants who are 4 months and their mother.
Infants born 3 weeks within their due date.
Infants of a birth weight > 2500 g.
Infants with NO serious medical complications.
English-speaking families.

Exclusion Criteria:
Infants who were < 2500 g at birth.
Infants who experienced any serious medical complications.
Infants who were born > 3 weeks before the indicated gestational period.
Families who do not understand and do not speak English
Children's Health, Neurology
Not applicable
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State College, PA ,

Predicting Concussion Outcomes with Salivary miRNA

The purpose of this study is to identify changes in salivary micro ribosomal nucleic acid (miRNA) expression that are predictive of symptom duration and severity following mild traumatic brain injury (mTBI) in children. The primary endpoints of this study are as follows:1)Characterization of brain-related miRNA in the saliva of 250 children with mTBI and 200 age- and gender-matched controls between the ages of five and twenty-three years.2)Identification of a set of salivary miRNAs that is predictive of duration and severity of mTBI symptoms.

Saliva collection and surveys at baseline, 7 days, and 30 Days

$20

Yes
 

Jayson Loeffert
Brennen Harding - at bharding@pennstatehealth.psu.edu or 717-531-5656
Family and Community Medicine (HERSHEY)
 

All
All
This study is also accepting healthy volunteers
NCT02901821
STUDY00003729
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Inclusion Criteria:
5 to 23 years of age
Seen in the Penn State Pediatric Concussion Clinic within 2 weeks of most recent concussion

Exclusion Criteria:
Does not speak english
Periodontal disease
Ongoing seizure disorder, or other neurologic disorder
Drug or alcohol dependency
clinical diagnosis of severe TBI
Children's Health, Neurology, Sports Medicine
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Hershey, PA ,

Califormula Study: Calibrated Formula Feeding to Optimize Infant Growth

This pilot study seeks to determine if formula feeding recommendations that are adjusted using age and weight specific caloric intake recommendations can prevent excessive infant weight gain and reduce overweight in the first 6 months after birth among infants born to mothers with overweight prior to pregnancy electing to exclusively formula feed their infants.

There will be 5-7 visits, where you will record formula volumes on diary cards for a total of 6 days per visit, and be given formula volume recommendations if you are in the intervention group. All participants will complete surveys when their infants are 1 and 6 months of age.

$300

Yes
 

Ian Paul
Courtney Byrnes - at cbyrnes@pennstatehealth.psu.edu or 717-531-0003, ext=322458
Pediatrics: General Pediatrics (HERSHEY)
 

All
Younger than 18 years old
This study is also accepting healthy volunteers
NCT05104073
STUDY00018788
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Inclusion Criteria:
Formula-fed infants
Term or Early term Infants (≥37 weeks)
Infant birthweight ≥50th percentile

Exclusion Criteria:
Infants who weigh less than their birthweight between 14-21 days after delivery
Children's Health, Food & Nutrition
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Hershey, PA ,

Normalizing preteen HPV vaccination with practice-based communication strategies (Protect Them)

This study seeks to adapt and test a culturally-relevant, web-based game intervention to motivate Spanish-speaking preteens to initiate and complete human papillomavirus (HPV) vaccination. The present study will adapt an existing web-based game developed as an educational tool on HPV vaccination for English-speaking preteens in North Carolina. The study includes the recruitment of paired dyads (Spanish-speaking preteens and parents) to focus groups to evaluate the acceptability of cultural adaptations to the existing web-based game intervention. We will recruit up to 25 parents and preteens ages 11-12 who will receive a link to the Spanish game to play for 7-10 days in advance of the focus group discussions. The focus groups will ask participants about cultural and language adaptations to the existing game and how they react to a game that will serve as an interactive, educational tool on HPV vaccination. The focus groups will take place in Harrisburg, PA between January and March of 2018. No health information will be collected as part of this study.

Yes
 

William Calo
William Calo - at wcalo@phs.psu.edu or 717-531-3535
Public Health Sciences (HERSHEY)
 

All
All
This study is also accepting healthy volunteers
SITE00000339
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Inclusion Criteria:
Pretens 11 or 12 years old
Not vaccinated with the HPV vaccine
Have computer, tablet, or smartphone

Exclusion Criteria:
Having received the HPV vaccine
Children's Health, Prevention
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Harrisburg, PA ,

Nurse Situation Awareness in ICUs

This is an interview and survey study that will examine how the design of ICU warning information system influence nurses situation awareness.

This study aims to understand how the design factors of warning information system influence nurse situation awareness in ICUs. You will participate an online interview study and fill out two questionnaires. The study takes 1-2 hours.

$30

No
 

Yiqi Zhang
Yiqi Zhang - at yuz450@psu.edu
Industrial and Manufacturing Engineering (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00020979
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Inclusion Criteria:
Be a practicing nurses or a nursing student who has clinical experience in ICU settings

Exclusion Criteria:
NA
Children's Health, Education, Mental & Behavioral Health
Not applicable
I'm interested
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