The objectives of this study are to understand attitudes, emotional response, and behavioral intention related to receiving COVID-19 public health messaging via the Wireless Emergency Alert system.

Measures of actual human-machine interaction are required to generate ecologically valid, translatable discoveries that enhance human-systems integration and performance. Here, the proposed methods center on human-robot decision tasks to assess key determinants of human trust in robot recommendations (e.g., factors such as threat-salience and/or robot appearance), and the concomitant impacts of trust on performance.

There will be one in person visit, you will be asked to interact with a robot in a virtual environment.

10

Reducing intake from large portions is of critical importance to preventing obesity. People consistently eat more when they are served larger portions, a phenomenon known as the portion size effect. The mechanisms of the portion size effect are not well understood, and investigating the underlying neurobiology that drives this phenomenon may inform the development of more effective obesity prevention programs. The proposed research will follow healthy weight children who vary by family risk for obesity to identify the neurobiological and appetitive traits that are implicated in overeating and weight gain during the critical pre-adolescent period. We expect results to confirm the hypothesis that reduced function of brain inhibitory pathways and increased activity in brain reward pathways in response to portion size cues contributes to excess intake with large portions and greater weight gain over time, particularly in children who have higher risk for obesity. The proposed studies will characterize the relationship between brain response to portion size and eating behavior and will allow us to determine whether brain and behavioral responses predict body fat gain during pre-adolescence. These studies will contribute essential information to our understanding of the pathways implicated in overeating and obesity and will facilitate the characterization of “at risk” phenotypes that can be targeted by prevention programs.

There will be seven in person visits with two DEXA measurements, one fMRI scan and five meals.

$350

This research study is being done to gather information from parents to figure out strategies and difficulties in their coparenting relationship for an intervention program which helps them to navigate the transition to parenthood process more comfortably and build up supportive relationships between parents.

We are experiencing global outbreak of coronavirus (COVID-19) recently. Millions of people are suffering and dying every day, in spite of putting our best efforts. We are doing this survey to understand people’s reaction to this situation. The survey will ask about your knowledge, practices and worries. Your response will help us to understand how to better control these situations. Your feedback is highly important to us, as we need to find out the best way to stop the disease from spreading and killing thousands of lives, and to reduce the stress among the population.

This study will use interviews to explore to explore perceptions of rurality, physical activity behaviors and physical activity intervention preferences among rural older adults who live in Pennsylvania

This study aims to understand the association between young adults' perceived parenting, intolerance of uncertainty, and trait anxiety. Participant will be asked to complete a questionnaire that aims to answer the environment and parenting beliefs around which they were brought up, and if they face stressors and anxieties associated with them. This is a correlational study

This study is being done to answer the following question:Can tomosynthesis mammography, three-dimensional x-ray imaging of the breast, lower your chance of developing life-threatening breast cancer through routine screening compared with digital mammography, two-dimensional x-ray imaging of the breast?We are doing this study because we want to find out which of the two usual approaches to breast cancer screening are better in the early detection of life-threatening breast cancers.

This is a behavioral and neuroimaging study that will examine how food commercials affect the way a child eats and responds to food. Children enrolled in the study will complete 5 in-lab sessions that include eating meals and snacks, watching TV, and playing computer games. For one of these sessions, children will complete an fMRI scan. On the first and last visit to the lab, children will receive a DXA scan to assess their body composition.

We are looking for children to help us learn about how kids respond to different types of foods and food advertisements. The study consists of 5 visits to our facilities in Noll and Chandlee Labs, located on the University Park Campus. For 3 visits your child will eat test meals and snack buffets in our laboratory. On 1 visit we will use fMRI to take pictures of your child’s brain. We will use a DXA to scan for lean muscle and conduct an IQ test. These procedures are not harmful. You and your child will fill out questionnaires.Your child will also play computer games and watch commercials.

$250.00

The purpose of this voluntary research study is to determine the effects of different methods of promoting physical activity with wearable devices and technology.

Participants will participate in an 18-month study with virtual study visits.-Use provided digital tools (activity tracker and messages) to monitor physical activity-Set goals to increase physical activity levels based on national guidelines-Monitor weight and complete questionnaires at five times throughout the study (at the beginning, 3 months, 6 months, 12 months and 18 months)

Up to $235 and a Fitbit tracker and BodyTrace scale

This focus group study, funded by Penn State's Social Science Research Institute, brings together couples with preschool-aged firstborns who are pregnant with their 2nd child or who have given birth to their 2nd child within the last 12 months. Couples will be interviewed about how they worked together as a team (as coparents) to prepare their firstborn for the birth of the second child and to prepare themselves for 2nd-time parenthood.

This study aims to examine the effect of pedaling a compact elliptical device at the desk on employees' work productivity. This study also aims to evaluate the effect of different types of incentives on promoting desk-based pedaling.

The goal if this study is to determine if a new tool (PUSH stadiometer) can be used by parents to accurately and easily measure children's height in their home.

Participants will be required to attend 1 Zoom visit and 1 in-person visit on Penn State's University Park Campus. Each of these visits will last 30 minutes or less.During the Zoom visit, a researcher will help parents use a new tool (PUSH Stadiometer) to measure their child's height in their home.At the in-person visit, a researcher will measure the child's height and weight, and parents will complete a short survey.

20

This study will examine the effects of different brain games on cognitive and everyday activities in middle-aged and older adults. Participants will play either 20 or 40 hours of ENACT brain games on a study provided laptop. They will also complete daily surveys on a study-provided mobile phone for the duration of the study. These surveys will take approximately 5-6 minutes to complete per day. The study will last either 6 or 9 months depending on the brain game training time. The study will be done remotely from the comfort of home using study-provided mobile devices. Participants are compensated for their time.

Participants will play either 20 or 40 hours of ENACT brain games on a study provided laptop. They will also complete daily surveys on a study-provided mobile phone for the duration of the study. These surveys will take approximately 5-6 minutes to complete per day. The study will last either 6 or 9 months depending on the brain game training time. The study will be done remotely from the comfort of home using study-provided mobile devices.

$230

This is an intervention study that will examine the effect of black raspberry lozenges on mouth cell DNA damage in smokers.

Following one week of being in the study you will be given black raspberry lozenges to take 5 times daily for 8 weeks. Afterwards you will participate in the study for an additional 4 weeks for a ‘wash-out’ period where no lozenges are given. During study visits you will be asked to complete questionnaires, provide a urine sample, and a mouth cell sample by brushing the inside of your cheek with a toothbrush. You will smoke as you normally do throughout the study. You will record cigarette and lozenge use every day. You will complete 2 phone call interviews about your 24-hour food intake during the beginning and the end of the study.

$380

The purpose of this research study is to see if we can use micro-doppler signal technology to determine if someone has had an ACL reconstruction in the past. We will do this by comparing a group of people who have had the surgery against a group who has never had this surgery to see if this technology can tell the difference.

If you join this study you would be asked to come to a one-hour appointment at the Lebanon Valley College campus in Annville, PA and perform a variety of activities that are part of daily life, such as walking, jumping, and standing from a seated position. We'll ask you to complete a questionnaire on any musculoskeletal pain you're experiencing and report your demographic information.

50

The purpose of the study is to examine how individuals change over time and what impacts their development. In particular, we are interested in mental health outcomes in young adulthood. Participants will be required to complete a survey one time that will take about 10-15 minutes to complete. Participants will be eligible to win a $10.00 amazon gift card.

The primary objective of this study is to examine, via online focus groups, the perceptions that are held by potentially-eligible subjects in the PSH DPP program in regard to the importance of physical exercise, particularly within the context of diet, social connectivity, and stress reduction. These perspectives will then be used to help develop, test, and refine additional motivational text messages that can be used in a text messaging intervention. Participants will receive a $25.00 gift card.

Adults recently diagnosed with SARS-CoV-2 infection who use a 4-day combined intervention of nasal washes with 1% baby shampoo solution and oral gargles with Listerine Antiseptic® will have a reduced SARS-CoV-2 viral load compared to those using nasal and oral washes with normal saline. This combined intervention should be acceptable, tolerable and safe in this population. To test this, we are conducting a trial comparing the efficacy of a number of washes in reducing the oral and nasal SARS-CoV-2 viral load amongst adults.

At their home, participants will perform three nasal and oral rinses per day for 4 days and self-swab the nose and mouth before and after each morning rinse to collect specimens under the guidance of a zoom visit. On the morning of the 5th day participants will also self swab the nose and mouth for a final collection specimen. Participants will answer questions on an app and online platform.

100

This study is being conducted to determine whether patient navigation improves informed decision making for prostate cancer screening. Participants will be offered the opportunity to discuss and address issues related to PSA testing with a patient navigator over a one month period. Surveys at the beginning and end of this period will include health knowledge, opinions on telehealth, and barriers to health care. All sessions will be conducted virtually.

Complete short on-line questionnairesComplete at least one telehealth session with the Patient Navigator

100

Site For Protect Them-Spanish groups

The purpose of this research study is to understand how caregivers communicate with teenagers through the ups and downs of daily life. We would like to know how caregivers and teens in a modern family act around each other, and how family communication affects well being. The study is conducted all online (e.g., video chats and surveys on phones).

Parent-teen pairs will be asked to do the following:1. A 2-hour baseline Zoom appointment2. Brief 1-2 minute long surveys throughout the day for one to two weeks3. Provide brief video recordings of their interactions during car rides over the one to two week period4. Carry study-provided smartphones with them at all times when not at school5. A 30-minute follow-up Zoom appointment

$100 per person

The purpose of this study is to investigate the underlying biological causes of the loss of pleasure in individuals diagnosed with depression. This study will examine brain, behavioral, and inflammatory markers of depression. Participants will answer questions, give blood and saliva, undergo fMRI and perform computer tasks. The study is also recruiting healthy controls with no history of major mental illnesses.Participants will be compensated $130 in total. To limit time in-person, the first portion of the study will be conducted remotely (1.5hrs), followed by an in-person appointment (3hrs). Mandatory COVID-19 precautions will be taken to ensure safety for the in-person appointment.

There will be one virtual visit where participants will review consent, answer questions about their mental health, and complete online questionnaires. There will also be one in-person visit where blood will be drawn, vitals (blood pressure, height, weight, and pulse) will be taken, participants will undergo an fMRI scan and complete computer tasks, and saliva samples will be collected at 3 time points.

$130

This project seeks to take advantage of emerging strategies for remote research and self-collection of biospecimens for wider use in research on families with and at-risk for substance use disorders and to refine/expand them to enhance substance use treatment and medical care possible through telehealth paired with remote sample/assessment strategies.

You will be asked to complete online questionnaires, watch videos and provide a hair sample, and give your opinion about your willingness to participate in research similar to that presented in the video content. Giving your opinion about this research may take place in the form of focus groups and/or interviews. Focus groups and interviews may occur either in-person or via Zoom depending on individual’s comfort with in-person contact and the amount of distance researchers and participants would need to travel.

$50

The purpose of this study is to conduct semi-structured interviews with students at Penn State who are working towards degrees in fields that require a high vocal demand (e.g. teachers, lawyers, singers, actors, etc). The purpose is to learn more about what students think about their voice, what they know about protecting their voice, and what they would do if they had a voice disorder. This information can be used to design interventions and preventative outreach programs for these students.

The purpose of this study is to see if stool or blood can be used to determine whether or not a patient has any colon polyps or colon cancer. This study will compare these biological samples (blood, urine, stool) to any colonoscopy or surgery a patient has to see if the outcome could be predicted.

This is a qualitative study that will examine the sex education experiences of sexual and gender minority emerging adults and help inform the development of inclusive comprehensive sex education curricula.

Participants will be asked to complete a one time interview about their sex education experiences. We will conduct one in-depth interview via Zoom for each participant. The interview will be audio and visual recorded. Interviews will take place in a private setting of the subjects’ choice. Interviews will be approximately 30-60 minutes.

$20

This study explores participants mood and how it changes from day to day and how mood and other things like personality and relationships influence thoughts of suicide or self-harm. Participants will both track and be able to visualize their mood and other experiences on a daily basis from their own smartphones.

There will be a set of questionnaires to complete online that will last between 45 and 90 minutes. Then participants will complete very brief (about 2 minute) surveys a few times per day on their smartphone over 12 weeks.

$140

This study is being done to find out how whether sleep duration is associated with pain responses and if a sleep intervention predicts a higher tolerance and a higher threshold for pain. This is a 21-day study. Participants will be asked to wear sleep-monitoring watches. Pressure pain and cold pain will be measured at study visits.

There will be four in-person visits. Pain will be measured during visits 2-4. Blood will be drawn during visits 2-4. Retinal images will be captured during visits 2-4. Participants will also be asked to complete surveys during each study visit and to provide screen shots of their phone screen use at visits 2-4.

$150

Pfizer, in collaboration with the European company Valneva, is developing a vaccine called VLA15 to protect people against an infectious disease called Lyme borreliosis, also known as Lyme disease (LD).

If you participate in the study, you will be assigned by chance (like flipping a coin) to receive either VLA15 or placebo. If you are included in the lot consistency portion of the study, you will receive either VLA15 (1 of 3 different lots) or placebo. VLA15 and placebo are referred to as “study vaccine” throughout this form. You will receive a 3-dose primary vaccination series at about 0, 2, and 5 to 9 months and then a booster dose about 12 months later. The study vaccine will be given as a 0.5 mL (about 1/10 of a teaspoon) injection administered in the muscle of the top part of your arm. There will be seven in person visits and blood will be drawn at four of these visits.