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Search Results Within Category "Women's Health"

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Effects of amiloride on walking ability in patients with peripheral artery disease

The purpose of the study is to determine the effects of amiloride on the blood pressure response to walking in PAD patients and healthy controls.

In each visit, you will be asked to walk on a treadmill. You will also be asked to take capsules prior to visit 2 and 3. The capsules for one visit will be a drug called amiloride (10mg, in 2 capsules with 5mg of amiloride in each capsule), which was traditionally used to lower blood pressure. The other capsules will be a placebo (no active medication). A blood sample will be drawn at each visit.

You will receive $25 per hour for your participation in this research study

Yes
 

Jian Cui
Cheryl Blaha - at cblaha@pennstatehealth.psu.edu or 717-531-1605
Heart and Vascular Institute (HERSHEY)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00018296
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Inclusion Criteria:
Men and women age 21- 85 years
Any race or ethnicity
Healthy: Free of acute medical conditions
PAD: Diagnosis of PAD, no pain at rest

Exclusion Criteria:
Pregnant or nursing women
Resting blood pressure of 150/100 or higher
Already taking amiloride
Recent heart attack or epilepsy
Peripheral neuropathy
Men's Health, Heart & Vascular, Women's Health
Not applicable
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Hershey, PA ,

Healthy Mom Zone: Control Systems Engineering for Optimizing a Prenatal Weight Gain Intervention Study 2.0

The proposed overall research aims to establish feasibility of delivering an individually-tailored, behavioral intervention to manage gestational weight gain [GWG] that adapts to the unique needs and challenges of overweight/obese pregnant women [OW/OB-PW] and will utilize control systems engineering to optimize this intervention; in other words, make this intervention manage GWG in OW/OB-PW as effectively and efficiently as possible.

You will be randomized into an intervention or attention control group from ~8 weeks gestation to ~37 weeks gestation with a BMI of 24-45 (>40 with physician consent).You will have 1 pre-intervention session that explains the study procedures and to get you ready for the study. Here you will also complete various measures of demographics, behavioral surveys, etc.Over the course of the study, you will weigh yourself each day, wear an activity monitor and complete various surveys. If you are randomized to the intervention group, you may have healthy eating demonstrations and/or physical activity sessions each week.You will have 1 post-intervention session where you will return your devices, complete a 30-60 minute interview and complete the last of the surveys.

$175

Yes
 

Danielle Downs
Abigail Pauley - at healthymomzone@psu.edu
Kinesiology (UNIVERSITY PARK)
 

Female
18 year(s) or older
This study is also accepting healthy volunteers
NCT05807594
STUDY00019075
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Inclusion Criteria:
Pregnant women
18-45 years old
8-18 gestational weeks
English speaking
BMI 24-45 (>40 with provider consent)

Exclusion Criteria:
Non-pregnant
Men
Younger than 18
Non-English speaking
BMI <24
Pregnancy & Infertility, Mental & Behavioral Health, Women's Health
I'm interested
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Altoona, PA ,
State College, PA ,

Postmenopausal women and their endothelium: Is dietary nitrate supplementation protective?

Heart disease is the leading cause of death in the United States. The loss of estrogen from menopause puts women at a greater risk of developing heart disease. The purpose of this study is to determine the effects of drinking beetroot juice on measures of blood vessel health and blood pressure. Participants will drink beetroot juice and placebo juice each for one week followed by blood pressure measurements and ultrasound imaging of an artery in the upper arm. A sub-aim of this study is to investigate the effects of estrogen status on blood vessel function between pre- and post-menopausal women.

There are a total of 6 in-person visits to the Clinical Research Center. You will be asked to drink beetroot juice (2 oz) every day for 7 days. Participants will undergo vascular assessments, blood pressure measurements, and blood draws (11 in total for 6 visits).

$120

Yes
 

David Proctor
Jocelyn Delgado - at jmd956@psu.edu or 408-679-8390
Kinesiology (UNIVERSITY PARK)
 

Female
18 year(s) or older
This study is also accepting healthy volunteers
NCT03644472
STUDY00010017
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Inclusion Criteria:
Post-menopausal women (1-6 years since menopause preferred)
BMI <35
Blood pressure <130/80
LDL <170 mg/dL

Exclusion Criteria:
Individuals taking hormone therapy
Individuals with resting blood pressure > or = 130/80 mmHg
Users of any tobacco and/or nicotine products (smokers, chewing tobacco, nicotine-containing patches/gum, smokeless cigarettes)
Individuals with any overt cardiovascular, metabolic, hematologic, pulmonary, renal, musculoskeletal, and/or neurological disease(s)
Individuals with active cancer
Food & Nutrition, Heart & Vascular, Women's Health
I'm interested
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Altoona, PA ,
State College, PA ,

Women and Infants' Stress and Health

The goal of this study is to understand how babies and their mothers learn to respond to stress during the early years of the baby's life. Participating women complete questionnaires and do a mildly stressful task alone (during pregnancy) or with their babies (at four different times over the first two years of the baby's life) and collect saliva samples that tell us about stress responses, either at home or at one of our lab sites. We aim to use what we learn to better support expecting parents who may be at risk for stress-related health problems and improve their children's resilience to stress throughout life.

Women are asked to participate in six sessions over Zoom and/or at the PACT Center between their 28th week of pregnancy and when their child is 2 years old. During these sessions, which last up to 2 hours each, mothers and babies will1.participate in mildly stressful tasks (like having the mother leave the room for up to 3 minutes and then return) and games to assess the baby’s emotional and cognitive development2.provide saliva samples by drooling into a tube (for the mother) or holding a cotton swab in their baby’s mouth to get it wet3.fill out questionnaires about themselves and their baby4.take part in clinical interviews that ask about mood and other markers of psychological ill-being

$220

Yes
 

Heidemarie Laurent
Sandra Rosario - at PRISMlab@psu.edu or 814-867-6482
Human Development and Family Studies (UNIVERSITY PARK)
 

All
All
This study is also accepting healthy volunteers
STUDY00019133
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Inclusion Criteria:
Pregnant (up to 32 weeks gestation)
18 or older
English speaking

Exclusion Criteria:
Unable to participate in either Harrisburg or State College study site at 15-24 months postnatal
Pregnancy & Infertility, Mental & Behavioral Health, Women's Health
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Harrisburg, PA ,
State College, PA ,

The Impact of Menstrual Cup Distribution Programming on College Student Perpetuation of Period Stigma

This is a social sciences study to analyze the effect of menstrual cup introduction through the "CampusCup" free menstrual cup distribution program on the tendency of college students to perpetuate period stigma. A survey will be conducted across samples of students who participated in the CampusCup program, students who use menstrual cups independent of the CampusCup program, and students who have never used menstrual cups. The survey will address motivations behind menstrual cup usage and personal attitudes towards periods. The study seeks to investigate relationships between menstrual cup usage &amp; CampusCup participation and impacts on community attitudes towards menstruation.

No
 

Jessica Strait
Jessica Strait - at jls7571@psu.edu
Information Sciences and Technology (UNIVERSITY PARK)
 

Female
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00018450
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Inclusion Criteria:
Currently enrolled as an undergraduate student at a US-based university
At least 18 years of age
Has experienced a menstrual period in the last calendar year

Exclusion Criteria:
Not currently enrolled as an undergraduate student in a US-based university
Less than 18 year of age
Has not experienced a menstrual period in the last calendar year
Education, Mental & Behavioral Health, Women's Health
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Mental wellbeing during the Covid-19 pandemic: a study of essential workers and social media use

Through in-depth interviews, we examine how the Covid-19 pandemic has impacted the daily lives and mental well-being of essential workers, as well as their use of social media.

No
 

Saeed Abdullah
Johnna Blair - at jlb883@psu.edu
Information Sciences and Technology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is NOT accepting healthy volunteers
STUDY00015851
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Inclusion Criteria:
Considered an “essential worker”---working outside of their homes during the Covid-19 pandemic (e.g. front line medical professionals, paramedics, hospital workers, grocery store employees, delivery drivers, factory workers, etc.)
Social media users (e.g. Twitter, Instagram, Facebook)
Adults 18 or older
Social media users

Exclusion Criteria:
Considered "non-essential" workers during the Covid-19 pandemic
those working from home during the Covid-19 pandemic
minors (those under 18)
those who do NOT use social media
Men's Health, Mental & Behavioral Health, Women's Health
I'm interested
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Smart Connected Water Bottle and Lighting Devices: A Prenatal Pilot Study

We will conduct a pilot study to test feasibility of an innovative light device and blue-light glasses for promoting better sleep and a novel, smart water bottle for proper hydration. We will also examine women’s sleep and hydration behaviors in relation to their perceptions of pain, and obtain feedback from the participants on the overall patient intervention content to reduce prescription opioid use and promote behavioral pain management strategies after delivery.

Currently recruiting pregnant women who are in their 2nd or 3rd trimester.Attend a pre-session (in person OR remote) to explain the use of the water bottle, lighting devices, activity monitors, and weight scaleUse the devices for 22 days and complete surveys in your own homeAttend a post-session (in person OR remote) to return devices and participate an interview about the last 22 days

$100

Yes
 

Danielle Downs
Abigail Pauley - at amp34@psu.edu
Kinesiology (UNIVERSITY PARK)
 

Female
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00019938
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Inclusion Criteria:
Pregnant
2nd or 3rd trimester
18-45
Reside around State College, PA

Exclusion Criteria:
Sleep apnea/diagnosed sleep disorders
Diagnosed eating disorders/extreme dietary restrictions
Currently diagnosed with gestational diabetes
Currently diagnosed with pre-eclampsia
Not pregnant
Pregnancy & Infertility, Sleep Management, Women's Health
Survey(s)
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State College, PA ,

AWS-PSU: Active Women's Study at Penn State University

AWS-PSU: Active Women's Study at Penn State University This research study is being conducted to evaluate the impact of exercise and reproductive function on bone strength. Eligible young women (age 18-30) are those that are generally healthy and either a) exercising and experiencing regular or irregular menstrual cycles, or b) not exercising and experiencing regular menstrual cycles.

Yes
 

Mary Jane De Souza
Nicole Aurigemma - at nca11@psu.edu or 814-863-4488
Kinesiology (UNIVERSITY PARK)
 

Female
18 year(s) or older
This study is also accepting healthy volunteers
PRAMS00043507
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Inclusion Criteria:
Regular or irregular menstrual cycles
Age 18-30
BMI between 16-29.9
No hormonal contraception for 6 months

Exclusion Criteria:
Smoking
Currently using medication impacting bone
Food & Nutrition, Muscle & Bone, Women's Health
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State College, PA ,

Human-Centric Non-Invasive Physiological Sensing System for Early Detection of Workers’ Heat Stress in the Field

This study will examine different structural designs of stretchable, skin-like sensors on the surface of human skin for workers.

There will be one in person visit;Subjects will first be asked to sit still for 3 minutes and then move their skin by the research team for another 3 minutes.

Yes
 

Larry Cheng
Huanyu Cheng - at huc@psu.edu or 814-863-5945
Engineering Science and Mechanics (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00020880
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Inclusion Criteria:
no existing skin conditions or open wounds, or other disorders that make them have altered temperature responses
be over 18 years old
must understand English
resources from Penn State, University Park

Exclusion Criteria:
people with a metal allergy
Men's Health, Women's Health
Prefer not to display
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State College, PA ,

Voice Perception Study

This is a voice perception study that asks participants to listen to voices and rate on various attributes such as attractiveness, social status, health, and others.

No
 

Toe Aung
Toe Aung - at txa96@psu.edu or 775-225-1747
Anthropology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is NOT accepting healthy volunteers
STUDY00009763
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Inclusion Criteria:
Age 18-40
Gender/Sex: Men/Male; Women/Female
Education: PSU students and participants recruited online

Exclusion Criteria:
Uncorrected severe defects of hearing
Participants who already completed the survey
Participants who took the survey on the mobile phone
Men's Health, Women's Health
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Mindful Moms study

This study (Mindful Moms) is being done to understand how an 8-week app-based mindfulness program called Calm impacts breastfeeding and maternal well-being. Eligible participants will be asked to complete three online surveys (each survey will take about 20 minutes) and take part in an 8-week app-based mindfulness program. Eligible participants will also be asked to take part in one online interview that will take about 25-30 minutes once the mindfulness program is over.

Participants will take part in one of two groups: A group asked to take part in a free 8-week app-based mindfulness program on their smartphone starting when they are 36 weeks pregnant or 4 weeks after delivery. The program will teach participants about mindfulness and breathing strategies to assist with calming their mind and body. or A group asked to take part in a free 8-week app-based mindfulness program on your smartphone starting 4 weeks or 12 weeks after they deliver. The program will teach participants about mindfulness and breathing strategies to assist with calming their mind and body. Participants will also be asked to complete three online surveys (each survey will take about 20 minutes) and take part in one online interview that will take about 25-30 minutes once the mindfulness program is over.

$130

No
 

Amy Moore
Amy Moore - at amm9107@psu.edu or 814-865-6714
Center for Childhood Obesity Research (UNIVERSITY PARK)
 

Female
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00018380
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Inclusion Criteria:
18 years of age or older
currently pregnant (12 to 34 weeks) or recently delivered (within the past 4 weeks)
intend to or are currently breastfeeding
daily access to a smartphone
willing to download a free mobile app

Exclusion Criteria:
have a current daily meditation practice
Food & Nutrition, Pregnancy & Infertility, Women's Health
I'm interested
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Early Identification in Older Adults of Risks to Sleep Health, Movement, and Cognition Using Ecological Methods

This proposal is a prospective study in which we will collect both subjective and objective quantitative data from older adults residing in independent living retirement communities, microlongitudinally (~1wk). Comprehensive measures of sleep health, cognition, and movement will be collected at community residences. The first phase of this project will recruit local, State College area adults over 70 residing in independent living facilities (e.g., Foxdale Village and The Village at Penn State). A second phase of data collection will extend to community-based older adults in rural parts of Centre and nearby counties.With this prospective, microlongitudinal information we will evaluate the characteristics of sleep predictive of daytime cognitive and neurobehavioral function and use those conclusions to inform nonpharmacologic, preventative interventions for older adults.

After consent, there will be 6 study visits at either Penn State University Park campus or at the participant's personal residence. Study participation lasts about 1 week.Participants wear non-invasive ambulatory watch-like activity monitors throughout (both day and night) the week. Participants complete electronic surveys and cognitive tests 6 times daily, with additional surveys at study conclusion.Sleep and daytime brain and heart activity are recorded (without video) using non-invasive clinical-type wire sensors applied to the face, head, and chest. Wires are worn on the face, head, and chest throughout the first two study nights. Wires are worn on the head and chest throughout the first two study days. There is not a sleep intervention in this study. We are collecting data about the typical sleep health of older adults and its relation to cognitive health.

$350

Yes
 

Orfeu Buxton
Margeaux Gray - at ecosleep@psu.edu or 814-863-5800
Biobehavioral Health (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00011786
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Inclusion Criteria:
>=50 and <91 years of age
Resident of PA, Centre County region
Living without functional assistance
Able to walk unassisted for at least 5min

Exclusion Criteria:
Previous participants are not eligible
Evidence of cognitive impairment (will be tested)
Men's Health, Sleep Management, Women's Health
Not applicable
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State College, PA ,

Modifiable Prevention and Early Intervention Targets for Unhealthy Eating Behaviors: A Study in First Year Undergraduates

This is a research study investigating the prevalence and manifestation of unhealthy eating behaviors and the relationships of energetic status, cognitive function, and reproductive health in a population of first year college students.

Phase 1 will involve a minimum of 1-2 visits, and completion of surveys about your general health, exercise and nutrition history, eating behaviors and attitudes, stress, and reproductive health, as well as cognitive testing and hair sampling. For those who qualify, Phase 2 will involve approximately 4 additional visits. Each visit will be about 2 hours. The visits include completion of surveys about general health, exercise and nutrition history, eating behaviors and attitudes, stress, and reproductive health, as well as cognitive testing and physiological measurements including blood and hair sampling, and tests of metabolism. Study participation will last at minimum about 1 week, and at maximum completion of Phase 1 and Phase 2 will occur over the course of a full academic year.

$25 per visit, up to $75

Yes
 

Nancy Williams
Jaime Rodden - at whel@psu.edu
Kinesiology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00022878
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Inclusion Criteria:
First Year College Student
Age 18-25 Years
BMI 16.5-30 kg/m2
No apparent metabolic, endocrine, or musculoskeletal disease.

Exclusion Criteria:
Pregnancy or intention to become pregnant in the next 9 months
Serious or chronic health condition (including thyroid illness, metabolic disease)
Unwilling to adhere to study protocol
Lactating
Does not speak English or are unable to give consent
Men's Health, Mental & Behavioral Health, Women's Health
Not applicable
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State College, PA ,

Driver Training on the Advanced Driving Assistant System

This research aims to study the training knowledge that is essential for drivers to use Advanced Driving Assistant Systems safely and properly and identify the optimal training approaches.

If you participate in the first experiment, you will receive training of the in-vehicle system via videos and manuals, complete a driving task on the driving simulator, and answer questions from questionnaires. If you participate in the second experiment, there will be two visits. In the first visit, you will receive training via watching and interacting with online videos, watching an experimenter operating ADAS at the test track, or practicing the functions of ADAS in a vehicle at the test track. The functions in the training include adaptive cruise control, lane-keeping assistance, and Highway Driving Assist. In the second visit, you will complete a driving task on the driving simulator and answer questions from questionnaires.

$30 for experiment1 and $60 for experiment 2

Yes
 

Yiqi Zhang
Ruby Kim - at rubykim@psu.edu
Industrial and Manufacturing Engineering (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00020300
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Inclusion Criteria:
Being over 18 years old
Being fluent in English
Have a valid driver license for at least one year
have normal vision or corrected vision only wearing contact lenses

Exclusion Criteria:
NA
Education, Mental & Behavioral Health, Women's Health
Not applicable
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State College, PA ,

Respect and Satisfaction in Same-Sex Romantic Relationships

The purpose of this study is to expand on previous research looking at respect and relationship satisfaction among heterosexual relationships and compare it to that of same-sex relationships to find where they are similar or different. Participants will complete self-report measures regarding their romantic relationships, including respect toward partner, satisfaction, and attitudes toward love. 30 minutes will be required for the study.

No
 

Michelle Yarwood
Michelle Yarwood - at mxg925@psu.edu or 814-867-4851
Psychology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00014276
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Inclusion Criteria:
age 18 years or older

Exclusion Criteria:
younger than 18 years of age
Men's Health, Mental & Behavioral Health, Women's Health
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Daily Thought Monitoring Study for Anxiety and Depression

This study aims to assess the relations among our daily thought patterns, positive emotions, everyday experiences, and cognitive functioning abilities. Eligible participants will complete a series of online questionnaires, a short 15- to 25-minute psychological interview, and brief cognitive functioning tests at Day 1 and Day 16. All visits will occur via Zoom. In between study visits on Day 1 and Day 16, they will be prompted to complete smartphone-delivered assessments of cognitive functioning, symptoms, and experiences for 14 days, 5 times a day. This is important to inform clinicians and researchers on how best to develop effective digital mental health therapies.

During Day 1, participants will undergo a brief 15- to 25-minute clinical interview over Zoom. After the clinical interview, if participants meet the study eligibility criteria, we will continue with the procedures outlined below. Otherwise, if they are ineligible for the study, we will mention that this study is not suitable for them and provide the contact of mental health treatment services. Eligible participants will then conduct a series of self-report questionnaires and performance-based cognitive functioning tests for the next 35 minutes. Participants will then complete a series of 14-day brief ecological momentary assessments administered on their smartphone five times a day, for 14 days. Last, participants will return for a 35- to 45-minute visit on Day 15 to complete a series of self-report questionnaires and performance-based cognitive functioning tests.

15

No
 

Michelle Newman
Nur Hani Zainal - at nvz5057@psu.edu
Psychology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00018534
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Inclusion Criteria:
Over 18 years of age
Owns an Android or iPhone
Fluent in the English language
Scores on self-report questionnaires suggest person does or does not struggle with depression and/or anxiety
Pregnant women will be allowed to participate

Exclusion Criteria:
Owns a Life’s Good Android phone brand that does not support the app
Unable to consent
Younger than 18 years of age
Reports struggling with suicidal thoughts
Judged to have alcohol, substance use, and/or eating disorder
Men's Health, Mental & Behavioral Health, Women's Health
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A Phase 2a/b, Randomized, Double-blind, Placebo-controlled, Parallel Group, Multicenter, Clinical Study to Evaluate the Efficacy and Safety of OG-6219 in 3 Dose Levels, in Women 18 to 49 Years of Age with Moderate to Severe Endometriosis-related Pain

A 16 week double blind treatment period to investigate the safety and effectiveness of 3 doses of the study drug vs placebo for endometriosis related pain.

There will be 8 onsite visits and 2 phone visits, blood will be drawn at the onsite visitsThere is an ediary that must be completed every dayStudy exams include a TVU ultrasound, ECG, vital signs, urine pregnancy tests and blood work

$1477.00

Yes
 

Stephanie Estes
Amyee McMonagle - at amcmonagle@pennstatehealth.psu.edu or 717-531-4484
Medicine: Endocrinology, Diabetes and Metabolism (HERSHEY)
 

Female
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT05560646
SITE00001406
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Inclusion Criteria:
premenopausal women
age 18-49
documented surgical diagnosis of endometriosis
moderate to severe endometriosis pain
regular menstrual cycles

Exclusion Criteria:
hysterectomy or bilateral oophorectomy
chronic pelvic pain not endometriosis related
pregnant or breastfeeding
hereditary abnormal hemoglobin or hemolytic anemia
uncontrolled hypertension
Women's Health
Experimental drug compared to a placebo/”sugar pill”
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Hershey, PA ,

A Randomized Controlled Pilot Study of the Use of Cannabidiol in the Management of Endometriosis Pain

We are looking to conduct a study looking at the effects of cannabidiol (CBD) in patients with endometriosis. We believe that CBD will improve both pain and quality of life. The study will last a total of 12 weeks and involve several onsite visits in addition to daily pain assessments.

There will be five in person visitsblood will be drawn at all of these visits

$175

Yes
 

Kristin Riley
Robinn Moyer - at rmoyer3@pennstatehealth.psu.edu or 717-531-6272
Obstetrics and Gynecology (HERSHEY)
 

Female
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT04527003
STUDY00013752
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Inclusion Criteria:
Females ages 18-45 years at the time of enrollment
Diagnosed with endometriosis by surgical diagnosis with direct visualization and/or histopathologic confirmation of endometriosis

Exclusion Criteria:
Women that are pregnant, breastfeeding or trying to conceive
Women with chronic daily opioid use ( > 14 days / month)
Women that are currently using Cannabis based products
Non-English speaking or inability to read and understand English
Pain Management, Women's Health
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Hershey, PA ,

TMIST_EA1151

This study is being done to answer the following question:Can tomosynthesis mammography, three-dimensional x-ray imaging of the breast, lower your chance of developing life-threatening breast cancer through routine screening compared with digital mammography, two-dimensional x-ray imaging of the breast?We are doing this study because we want to find out which of the two usual approaches to breast cancer screening are better in the early detection of life-threatening breast cancers.

Yes
 

Rebecca Sivarajah
Swati Shah - at sshah@pennstatehealth.psu.edu
Radiology (HERSHEY)
 

Female
18 year(s) or older
This study is also accepting healthy volunteers
NCT03233191
SITE00000587
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Inclusion Criteria:
Women age 45 or older and under age 75 at the time of study entry
Patients must be scheduled for, or have intent to schedule, a screening mammogram.
Patients must be able to tolerate digital breast tomosynthesis and fullfield digital mammographic imaging required by protocol.
Patients must be willing and able to provide a written informed consent.

Exclusion Criteria:
Women of childbearing potential must not be known to be pregnant or lactating.
Patients must not have new symptoms or signs of benign or malignant breast disease
Patients must not have had a screening mammogram within the last 11 months prior to date of randomization.
Patients must not have previous personal history of breast cancer including ductal carcinoma in situ
Patients must not currently have breast enhancements (e.g., implants or injections).
Prevention, Cancer, Women's Health
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Hershey, PA ,

Factors Influencing the Decision to Report Sexual Violence on Campus

Research project to understand why students do or do not choose to report sexual assault exposure to police or university officials.

One interview via video conferencing or in person.Optional follow up interview via video conferencing.

$35 for initial interviews; $12 for follow ups

No
 

Kamaria Porter
Kamaria Porter - at porterkb@psu.edu
Education Policy Studies (UNIVERSITY PARK)
 

Female
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00021495
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Inclusion Criteria:
Woman (cis-gender, nonbinary, Trans women)
experienced unwanted sex, assault, or harassment during higher education study
currently in undergraduate or graduate program
recently graduated, transferred, or pausing higher education program
Racial background is Black, Afro-Latina, Afro-Indigenous, Black Multiracial

Exclusion Criteria:
did not experienced unwanted sex, assault, or harassment during higher education study
Education, Women's Health
Not applicable
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Heart Rate Variability in Orthostatic Hypertension

The study will examine a condition known as orthostatic hypertension, which is a sudden increase in blood pressure when a person stands up. Orthostatic hypertension is a recognized risk factor for cardiovascular diseases. This project will also examine the differences in blood pressure responses to standing between African Americans and other races, since African Americans are more likely to develop high blood pressure than other races.

If you are eligible, you will be asked to complete the following activities in a single visit:• Lie down for 10 minutes while the team completes anelectrocardiogram (EKG) and blood pressure measurements• Stand up for 10 minutes while the team continues the EKGand blood pressure measurements

$25

Yes
 

Jian Cui
Cheryl Blaha - at cblaha@pennstatehealth.psu.edu or 717-531-1605
Heart and Vascular Institute (HERSHEY)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00017924
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Inclusion Criteria:
21 – 80 years of age
Are capable of giving informed consent
Are of any race or ethnicity
Can stand for over 10 minutes

Exclusion Criteria:
Age < 21 years of age or > 80 years of age.
Are pregnant or nursing women
Have a history of low blood pressure with standing or passing out.
Cannot stand for 10 minutes
History of blood clots
Men's Health, Heart & Vascular, Women's Health
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Hershey, PA ,

The role of thromboxane A2 and its receptor in vascular regulation in women with endometriosis

Women with endometriosis have more thromboxane being produced in their platelets. Thromboxane affects blood vessels, making them constrict, and sensory nerves, making them more sensitive. This study will determine if women with endometriosis are negatively effected by the excess thromboxane.

There will be three in-person visits: one screening and two experimental visits. Participants will take aspirin before one visit and a placebo before the other then will undergo brief tests of nerve sensitivity and a blood draw.

$150

Yes
 

Lacy Alexander
Sue Slimak - at sks31@psu.edu or 814-863-8556
Kinesiology (UNIVERSITY PARK)
 

Female
18 year(s) or older
This study is also accepting healthy volunteers
NCT05962034
STUDY00021851
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Inclusion Criteria:
18-48 years
born with a uterus
with and without endometriosis

Exclusion Criteria:
diagnosed cardiovascular disease
hormone replacement therapy within previous 2 months
nicotine use
pregnant or breastfeeding
aspirin allergy or hypersensitivity
Heart & Vascular, Pain Management, Women's Health
Approved drug(s)
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Hershey, PA ,
State College, PA ,

Women, Opioid Use Disorder, and Criminal Justice: A Qualitative Study

Opioid-related overdose deaths and incarceration rates have skyrocketed and have disproportionately affected women. Despite having a higher burden of substance use disorders and HIV/AIDS than criminal justice-involved (CJI) men, CJI women are less likely to have access to substance use and HIV treatment. This qualitative study will conduct in-depth interviews with CJI women, MAT providers, and criminal justice professionals to identify facilitators and barriers to illicit opioid use cessation and related issues among CJI women.

No
 

Abenaa Jones
Abenaa Jones - at avj5462@psu.edu
Human Development and Family Studies (UNIVERSITY PARK)
 

Female
18 year(s) or older
This study is NOT accepting healthy volunteers
STUDY00018974
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Inclusion Criteria:
women
substance use
opioid use
criminal justice
drug treatment

Exclusion Criteria:
Younger than 18 years of age
Addiction & Substance Abuse, Mental & Behavioral Health, Women's Health
I'm interested
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Optimizing Maternal Nutrition: Adaptive trials and molecular methods to improve maternal and newborn health

Poor maternal nutrition is linked to poor birth outcomes. Current vitamin and mineral recommendations in pregnancy are based on limited data mostly from animal models and non-pregnant people. This study seeks to improve our understanding of the amounts of vitamins and minerals that are needed during pregnancy, to improve the health of women and newborns, especially in low-and middle-income countries. Nutrients travel around the body in blood, therefore part of the research is to understand how much blood and the watery component of blood (plasma) increases in pregnancy. This is a collaborative study with George Washington University (lead PI is there). The Penn State team will conduct pilot work to establish a method for measuring plasma volume in 2 phases. In phase 1, nonpregnant will be asked to attend one visit and plasma volume will be measured by injecting indocyanine-green (ICG, a green dye) and hydroxyethyl starch (HES, a form of starch) through an IV in the arm. In phase 2, pregnant women will be asked to attend 2 visits that are 4 weeks apart, but only HES (the starch) will be injected. For both phases (1 and 2), blood draws will occur at each visit and other non-invasive measurements will also be taken (e.g. weight, height, blood pressure). Each visit should take less than 2 hours and will be conducted at the Clinical Research Center in Noll Laboratory on the Penn State campus.

In phase 1, nonpregnant will be asked to attend one visit and plasma volume will be measured by injecting indocyanine-green (ICG, a green dye) and hydroxyethyl starch (HES, a form of starch) through an IV in the arm. In phase 2, pregnant women will be asked to attend 2 visits that are 4 weeks apart, but only HES (the starch) will be injected. For both phases (1 and 2), blood draws will occur at each visit and other non-invasive measurements will also be taken (e.g. weight, height, blood pressure). Each visit should take less than 2 hours and will be conducted at the Clinical Research Center in Noll Laboratory on the Penn State campus.

$50 per visit

Yes
 

Alison Gernand
Leigh Taylor - at lam5935@psu.edu or 814-867-5938
Nutritional Sciences (UNIVERSITY PARK)
 

Female
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00016189
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Inclusion Criteria:
Are a female 18-44 years old
Are generally healthy with normal blood pressure and BMI
Phase 1 - not pregnant
Phase 2 - are currently pregnant (22-32 weeks)

Exclusion Criteria:
Known allergy to iodine, shellfish, or corn
Currently have low or high blood pressure
Taking regular medication(s) prescribed by a physician
Phase 1 - pregnant or breastfeeding
Phase 2 - multiple/twin pregnancy
Food & Nutrition, Pregnancy & Infertility, Women's Health
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State College, PA ,

Examining responses to rewards in the laboratory and during daily life in individuals who smoke cigarettes

The goal of this study is to learn more about how people who smokecigarettes respond to rewards, such as winning money, under different conditions. The study uses a method called functional magnetic resonance imaging, or fMRI, which is a research method for measuring activity in the brain. In this study, we are using fMRI to measure how brain activity changes in people who smoke when they receive rewards. The fMRI measures are collected during two separate visits. Participants are also asked to fill out questionnaires and complete computer tasks while in the lab. In addition, the study involves measuring thoughts and behaviors in people who smoke in real life by asking them to fill out surveys on a smartphone. Participants are asked to carry a smartphone for a total of 10 days and answer several surveys throughout each day. In order to be eligible for the study, individuals must be between 18 and 55 years old and you must smoke on a daily basis.

Yes
 

Stephen Wilson
Julian Peck - at jnp5021@psu.edu or 814-867-2333
Psychology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00003602
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Inclusion Criteria:
21-55 years of age
Right Handed
Smokes cigarettes

Exclusion Criteria:
under 21 years of age or over 55 years of age
Left Handed
non-smokers
Men's Health, Addiction & Substance Abuse, Women's Health
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Altoona, PA ,
State College, PA ,

The Penn State Personalized Research for Innovation, Discovery, and Education (PRIDE) Program.

The Penn State Personalized Research for Innovation, Discovery, and Education (PRIDE) Program.The aims of the PRIDE Program are to:1. Create a centralized Biorepository using extra blood obtained from a clinically-ordered, or another IRB approved research protocol initiated blood draw, leftover biospecimens that are removed during medically indicated procedures or a saliva sample from consented participants that do not have clinically ordered blood draws or a medical procedure.2. Construct a dynamic database of health and related data (via both manual and electronic abstraction) from consented participants.3. Establish a mechanism for approving use of the banked biospecimens for future research.

The participant will meet with PRIDE Program team member in person to join the study.The participant with supply a saliva sample for the program.There is no compensation for joining the PRIDE Program.

Yes
 

James Broach
Molly Pells - at IPM@pennstatehealth.psu.edu or 855-369-3540
Biochemistry and Molecular Biology (HERSHEY)
 

All
All
This study is also accepting healthy volunteers
PRAMS00040532
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Inclusion Criteria:
Any age
Ability of patient, child and/or parent to understand or complete the consent process

Exclusion Criteria:
Unable to understand or complete the consent process
Men's Health, Children's Health, Women's Health
Not applicable
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Hershey, PA ,

Future of Construction Workplace Health Monitoring

This study will examine different structural designs of stretchable, skin-like sensors on the surface of human skin for construction workplace health monitoring.

There will be one in person visit, you will be asked to sit still for 3 minutes and then move your skin for another 3 minutes.

Yes
 

Larry Cheng
Huanyu Cheng - at huc24@psu.edu or 814-863-5945
Engineering Science and Mechanics (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00020934
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Inclusion Criteria:
no existing skin conditions or open wounds, or other disorders that make them have altered temperature responses.
be over 18 years old.
must understand English.
from Penn State, University Park

Exclusion Criteria:
have existing skin conditions or open wounds, or other disorders that make them have altered temperature responses.
cannot understand English
under 18 years old
Men's Health, Women's Health
Prefer not to display
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State College, PA ,

Use of the Frequen-ZZZ Sleep Pad to Increase Restorative Sleep: A Proof-of-Concept Study

This research is a small, 8wk clinical trial testing the potential effects of an investigational device, Frequen-ZZZ/Sleepergize Sleep Pad, on the sleep of adults 40-65 years old. We aim to determine whether sleeping with the Sleep Pad, which creates an electromagnetic field around the sleeper, has an improving effect on sleep. Sleep will be primarily measured using a non-invasive clinical standard method, called polysomnography (PSG), for 6 separate nights in the personal residence of participants. Sleep will also be measured both day and night with a watch-like device that measures activity, and with surveys. We will look for changes in sleep quality, in sleep duration, and in the way that sleep is organized by the body. We will also measure changes in inflammation, which is related to sleep, from 3 blood samples collected during the study. There are 15-17 in-person appointments across the course of the study. With the data, we hope to also evaluate the feasibility and effect sizes of this non-pharmacological intervention to inform future research, and we plan to use data in support of a future FDA application for the device.

Participation involves sleeping with the investigational device, 6 separate nights of sleep monitoring in your home with standard equipment that is used in clinical settings, 3 blood draws, surveys, and wearing an activity watch, all over the course of an ~8wk participation period. There are 15-17 in-person appointments and about 15 active hours of engagement involved in the study.

$3,000.

Yes
 

Anne-Marie Chang
Anne-Marie Chang - at sleeppad@psu.edu
Biobehavioral Health (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
NCT05908344
STUDY00020435
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Inclusion Criteria:
40-65 years of age (inclusive)
At least some Insomnia symptoms
Living without assistance and able to sign own informed consent
Not a nocturnal shift or rotating shift-worker
English speaker/reader

Exclusion Criteria:
Current smoker
Diagnosed with a sleep disorder
Pacemaker
Pregnant, breast-feeding, or planning to become pregnant
Taking prescribed medication or therapy for sleep
Men's Health, Sleep Management, Women's Health
Experimental device
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State College, PA ,

Coping with it All from Labor to Maternity

The CALM Project is looking to learn how different birthing classes prepare child-bearers for parenthood. Participants attend a free birthing class between their 20th and 37th weeks of pregnancy with their partners and fill out three questionnaires during pregnancy and postpartum. Three months after their baby is born, they are video-recorded interacting with their baby in their home and have their brain scanned using MRI. We aim to understand how different childbirth classes support mothers' well-being and bonding with their babies.

Women are asked to 1.complete 3 self-report questionnaires online during pregnancy and after their baby is born (45 minutes each)2.attend a childbirth preparation class (from a few hours to a 9-week class)3.participate in 2 in-person sessions (1.5 hours each): a videorecording with their baby in the home and a brain scan using MRI at Penn State Hershey Medical Center.

$160 + free birthing class

Yes
 

Heidemarie Laurent
Sandy Rosario - at PRISMLab@psu.edu or 814-867-6482
Human Development and Family Studies (UNIVERSITY PARK)
 

Female
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00019138
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Inclusion Criteria:
Less than 28 weeks pregnant
At least 18 years old
Speaks English

Exclusion Criteria:
MRI contraindications (metal implants, brain injury, etc.)
Pregnancy complications that would prevent you from participating in an online class
Pregnancy & Infertility, Women's Health
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Harrisburg, PA ,
Hershey, PA ,

Psychological and Biological Determinants of Eating Disorder Pathology in Endurance and Aesthetic Athletes

The purpose of this study is to investigate psychobiological factors that impact the development and manifestation of eating disorder (ED) pathology in elite male and female athletes before and during their competitive season.

The purpose of this voluntary research study is to assess how changes in stress, cognitive flexibility, response inhibition, and reward delay predict the trajectory of eating disorder behaviors and associated side effects of energy deficiency from the off-season compared to the competitive season. Your participation in this study will last approximately the duration of one season of your sport, specifically 4-weeks of data collection prior to season commencement (baseline), 4-weeks of data collection during peak competition season, and 4-weeks of data collection during off-season. The total time spent in the lab will be approximately 10-14 hours. Procedures will occur three times and measurements will be taken twice following baseline measures (once during the peak competition season, once during off-season), if you agree to do so.

$50

Yes
 

Mary Jane De Souza
Ana Carla Salamunes - at whel@psu.edu or 814-863-4488
Kinesiology (UNIVERSITY PARK)
 

All
18 year(s) or older
This study is also accepting healthy volunteers
STUDY00018984
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Inclusion Criteria:
Age 18-25 years
A member of a Penn State NCAA Division 1 Sports team, or Penn State affiliated competitive club team, or competitive community sport team
Exercising without any training modifications that reduce training participation.
non-smoker
No serious of chronic health conditions

Exclusion Criteria:
BMI >32kg/m2 or <16.5 kg/m2
Currently a smoker or history of regular smoking (including nicotine products, e-cigarettes, vaping)
Medications influencing metabolic or endocrine factors (e.g., hormonal use in previous 6 months)
Medical instability or history of psychosis
Vasectomy (male) or Hysterectomy or oophorectomy (female)
Men's Health, Food & Nutrition, Women's Health
Not applicable
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State College, PA ,