Search Results Within Category "Mental & Behavioral Health"
Healthy Mom Zone: Control Systems Engineering for Optimizing a Prenatal Weight Gain Intervention Study 2.0
The proposed overall research aims to establish feasibility of delivering an individually-tailored, behavioral intervention to manage gestational weight gain [GWG] that adapts to the unique needs and challenges of overweight/obese pregnant women [OW/OB-PW] and will utilize control systems engineering to optimize this intervention; in other words, make this intervention manage GWG in OW/OB-PW as effectively and efficiently as possible.
You will be randomized into an intervention or attention control group from ~8 weeks gestation to ~37 weeks gestation with a BMI of 24-45 (>40 with physician consent).You will have 1 pre-intervention session that explains the study procedures and to get you ready for the study. Here you will also complete various measures of demographics, behavioral surveys, etc.Over the course of the study, you will weigh yourself each day, wear an activity monitor and complete various surveys. If you are randomized to the intervention group, you may have healthy eating demonstrations and/or physical activity sessions each week.You will have 1 post-intervention session where you will return your devices, complete a 30-60 minute interview and complete the last of the surveys.
$250
18-45 years old
8-18 gestational weeks
English speaking
BMI 24-45 (>40 with provider consent)
Men
Younger than 18
Non-English speaking
BMI <24
Women and Infants' Stress and Health
The goal of this study is to understand how babies and their mothers learn to respond to stress during the early years of the baby's life. Participating women complete questionnaires and do a mildly stressful task alone (during pregnancy) or with their babies (at four different times over the first two years of the baby's life) and collect saliva samples that tell us about stress responses, either at home or at one of our lab sites. We aim to use what we learn to better support expecting parents who may be at risk for stress-related health problems and improve their children's resilience to stress throughout life.
Women are asked to participate in six sessions over Zoom and/or at the PACT Center between their 28th week of pregnancy and when their child is 2 years old. During these sessions, which last up to 2 hours each, mothers and babies will1.participate in mildly stressful tasks (like having the mother leave the room for up to 3 minutes and then return) and games to assess the baby’s emotional and cognitive development2.provide saliva samples by drooling into a tube (for the mother) or holding a cotton swab in their baby’s mouth to get it wet3.fill out questionnaires about themselves and their baby4.take part in clinical interviews that ask about mood and other markers of psychological ill-being
$220
18 or older
English speaking
Slips of Action in Adolescents and Young Adults
Adolescence is a critical period during which many important healthhttps://irb.psu.edu/IRB/sd/ResourceAdministration/Project/ProjectEditor?Project=com.webridge.entity.Entity[OID[058ACDEB3E43384D816C7E390C2B83F6]]&Mode=smartform&WizardPageOID=com.webridge.entity.Entity[OID[E4552FC57E491543A6B7FD8268E23FD7]] habits form in humans. However, animal models provide mixed information about habit formation across development and there are relatively few human studies that address differences between habit formation in adolescents and adults. To address this gap, the proposed study will assess differences in habit formation in adolescents and adults as measured by the "Slips of Action" task, which seeks to discriminate between habitual and goal-directed learning of visual stimuli pairings.
There will be one in-person visit lasting about one hour. Visits will begin with informed consent. Participants will complete a computer task where they are asked to learn associations between pictures and then will be tested on the associated pairings. They will also complete questionnaires and cognitive tasks.
$20
Healthy adults between the ages of 25 to 40
No learning disabilities (e.g., ADHD) or diagnosed psychological conditions (e.g. anxiety)
Right handed
Not on any medications known to influence behavior
Diagnosed neurological or psychological condition including severe anxiety and/or depression, schizophrenia, learning disability, ADD/ADHD, or autism
Significant family history of neurological or psychological disorders
Left handed
Participant is on any medication that may influence behavior
The Impact of Menstrual Cup Distribution Programming on College Student Perpetuation of Period Stigma
This is a social sciences study to analyze the effect of menstrual cup introduction through the "CampusCup" free menstrual cup distribution program on the tendency of college students to perpetuate period stigma. A survey will be conducted across samples of students who participated in the CampusCup program, students who use menstrual cups independent of the CampusCup program, and students who have never used menstrual cups. The survey will address motivations behind menstrual cup usage and personal attitudes towards periods. The study seeks to investigate relationships between menstrual cup usage & CampusCup participation and impacts on community attitudes towards menstruation.
At least 18 years of age
Has experienced a menstrual period in the last calendar year
Less than 18 year of age
Has not experienced a menstrual period in the last calendar year
Penn State Hershey Sitting and Health Study
This study aims to examine the effect of pedaling a compact elliptical device at the desk on employees' work productivity. This study also aims to evaluate the effect of different types of incentives on promoting desk-based pedaling.
Overweight or obese
Spend at least 5 hours per day sitting at a desk
Have eligible overweight/obese coworker who can do study together with you
18-70 years old
Planned surgical or medical treatment that will prevent ability to complete study
Heart condition, or chest pain during physical activity
Planned travel or relocation during study period
Already have desk cycling device or treadmill at desk
Seeking support from romantic partners
The purpose of this study is to determine whether and how people's perceptions of the power in their romantic relationships shape the messages they use to seek support from their romantic partners.
Have you sought comfort, advice, information, esteem boosts, or emotional support from your romantic partner within the last 4 weeks?
People who are not in a romantic relationship
People who did not seek support from their romantic partner in the last 4 weeks.
People who do not have access to technology to compete the survey.
Mental wellbeing during the Covid-19 pandemic: a study of essential workers and social media use
Through in-depth interviews, we examine how the Covid-19 pandemic has impacted the daily lives and mental well-being of essential workers, as well as their use of social media.
Social media users (e.g. Twitter, Instagram, Facebook)
Adults 18 or older
Social media users
those working from home during the Covid-19 pandemic
minors (those under 18)
those who do NOT use social media
The Effects of Aircraft Seat Width on Passenger Comfort
The objective of this research is to determine the relationship between aircraft seat width and passenger comfort. Airlines are reducing the sizes of seats and improving their ability to fly planes at or near capacity. The combined effect is to decrease the quality of the experience of passengers. This work will help us to understand the degree to which comfort has been reduced.
You must be a healthy adult aged 18 years or older.
PLS Natural History Study
This study will provide a strong basis and foundation for future clinical trials that use historical controls. The study will collect clinical data and biological specimens to create a dataset and biorepository to be shared with other researchers as a foundation for future clinical trials.
This is a volunteer study for participants diagnosed with Primary Lateral Sclerosis (PLS) or suspected to have PLS by a neurologist. You will be expected to attend scheduled visits in person or by telephone, complete study testing and audio/video recordings. The study includes clinical measurements to assess disease status and motor function, a number of questionnaires, collection of biospecimens including DNA, blood, and urine, and an electromyography (EMG) test. There will be 6 visits over 24 months, of these 6 three will be in-person visits (2-3 hours) and the other three will be telephone calls (lasting about 45 minutes to an hour). Blood and urine samples will be collected during these visits.
$100 per in person visit (three) and $50 for telephone visit (three) completed.
Symptom onset was no more than 15 years prior to baseline
Ability to independently walk with or without an assistive device (e.g., walker) at the baseline evaluation
In cases where a molecular test has been done prior to enrollment in this study, HSP or HSP-related mutations are negative
Expected to have at least some bulbar symptoms (dysarthria, dysphagia, drooling or pseudobulbar affect); however, the absence of these symptoms will not exclude participants when molecular testing is negative for known HSP
UMN symptoms and signs only in the legs
Unwilling or unable to visit the study site asrequired
Clinically obvious cognitive impairment that precludes obtaining informed consent, as determined by the site PI
Participating in clinical treatment trials
Self-Help for Stress Related to COVID-19
This is a study on internet-based self-help for stress related to the COVID-19 pandemic. College and university students who screen high on perceived stress or measures of risk for anxiety, depression, or eating disorders during the COVID-19 pandemic will be invited to participate in this study. Participants will be randomly assigned to receive access to an internet-based self-help program for stress resilience and coping with the COVID-19 pandemic or care as usual. Symptoms of stress, anxiety, depression, and eating disorders, as well as secondary outcomes, will be assessed via questionnaire at baseline (pre-randomization), one month post-randomization, and three months post-randomization.
Participants will be randomly assigned to receive access to an internet-based self-help program for stress resilience and coping with the COVID-19 pandemic or care as usual. Symptoms of stress, anxiety, depression, and eating disorders, as well as secondary outcomes, will be assessed via questionnaire at baseline (pre-randomization), one month post-randomization, and three months post-randomization.
Up to $50 (raffle-based)
Fluent in English
Current college or university student
Under 18 years of age
Not a college or university student
Not fluent in English
Emotion in Motion: Behavior and Mental State Analysis on Human Visual Data
The main purpose of the proposed study is to examine the relationship between emotional body expression and internal emotional and psychophysiological processes among individuals with mental disorders in social interaction situations.
In this study, participants will be asked to answer structured questions. After this, participants will be asked to engage in emotional induction tasks, communicate with another person, and walk. During the interview and experimental procedures, your motion will be video recorded.
40
Fluent in English
Able to walk at a leisurely pace on a treadmill without assistance
Not fluent in English
Unable to walk at a leisurely pace on a treadmill without assistance
Experiencing cognitive impairments
Neurophysiological Markers of Pediatric Irritability and its Response to Intervention
This study uses specific computer tasks to predict irritability in children with Attention Deficit/Hyperactivity Disorder (ADHD), as well as the effect of ADHD medication (stimulants) on irritability symptoms in children with ADHD. Children ages between the ages of 5 and 12 years are eligible and must have an established diagnosis of ADHD or suspected symptoms of ADHD.
Children diagnosed with ADHD or suspected ADHD Symptoms
Children who are able to stop ADHD medication for testing days
Parent/child fluent in English
Children with visual or hearing deficits or sensitivity to loud noise
Neurological conditions such as active seizure disorder
Prominent traits or diagnosis of Autism, marked developmental delay, mania, psychoses, or suicidal ideation.
Depressive Symptomatology and Inflammation
The purpose of this research is to investigate the associations between depressive symptoms and inflammation. The researchers are studying how specific symptoms of depression (such as fatigue, sadness, impaired concentration, and loss of pleasure) are related to markers of inflammation, which is a key component of our immune system. Volunteers with depressive symptoms, as well as volunteers without depressive symptoms are needed for this research study. This study includes an online survey to determine eligibility and one in-lab visit. Participants who are eligible will be scheduled for one in-lab visit (2.5-3h for participants with depressive symptoms & 1-2h for participants without depressive symptoms), where they will be asked to answer surveys with questions related to depressive symptoms and complete a number of tasks (using an iPad and a touch screen phone) that measure thinking skills including attention, memory and reaction time. Participants will also undergo a single blood draw to assess inflammatory markers.
Participation will require one in person visit at the CRC that takes from 1 to 1.5 hours total where they will have their blood drawn, fill out surveys about their mood, and complete cognitive tests.
30
No history of depression
Free of chronic inflammatory or autoimmune disorders
If female, not pregnant or nursing
Taking non-steroidal anti-inflammatory agents or statins everyday within the past month
Taking antipsychotics or mood stabilizers
If female, are post-menopausal or pregnancy/lactation
Exploring the Needs and Challenges of Care Partners to Support Financial Management of Individuals with AD/ADRD
The project focuses on gathering initial evidence about the opportunities and challenges of designing tailored financial technology (fintech) to support the care partners of persons living with Alzheimer’s disease (AD) and AD-related dementia (ADRD) to help them with collaborative and longitudinal financial management. To accomplish this goal, we will conduct 20 min survey study and optional follow-up interview activities with care partners.
We are recruiting care partners of individuals living with Alzheimer's Disease and Alzheimer's Disease Related Dementias. There will be two phases in the study. The first phase is a 20-min survey that will ask participants about their financial management behavior. The second phase is optional, and it is a 40-min follow-up interview with similar questions.
For the first phase, each participant may choose to enter a drawing for a chance to win a $50 Amazon eGift card. For the second phase, each participant will receive a $30 Amazon eGift card for their time.
Ability to understand or speak English
Age range: over 21 years and less than 89 years.
Non-English-speaking respondents
Those who are NOT care partners of individuals living with Alzheimer's Disease and Alzheimer's Disease Related Dementias
The Blended4Blues Study
An intervention using an internet-based platform for coping and mood difficulties. Participants will be able to use cognitive-behavioral therapy (CBT) based online self-help modules over the course of a 10-week program.
Participants will engage with online materials on a weekly basis for 10 weeks.
$25
U.S. resident currently residing in the United States
Fluent in the English language in terms of speaking, listening, reading, and writing.
Aged 18-19 years
Presence of depressive symptoms as measured by a score ≥ 10 on the QIDS-17-SR
Unable to speak, read, listen, and write English fluently.
Do not meet inclusion criteria for clinical depression on the QIDS-17-SR, i.e., score ≥ 10
Does not fulfill DSM-5 Criteria for MDE on the MINI Clinical Interview.
Expressed suicidal ideation defined as score >1 on the suicide ideation item on the PHQ-9, and/or on the MINI.
A qualitative exploration of rurality, physical activity, and intervention preferences among older residents in Pennsylvania
This study will use interviews to explore to explore perceptions of rurality, physical activity behaviors and physical activity intervention preferences among rural older adults who live in Pennsylvania
Currently residing in Pennsylvania
Able to speak, read, and write in English
Not currently residing in Pennsylvania
Not able to speak, read, and write in English
Modifiable Prevention and Early Intervention Targets for Unhealthy Eating Behaviors: A Study in First Year Undergraduates
This is a research study investigating the prevalence and manifestation of unhealthy eating behaviors and the relationships of energetic status, cognitive function, and reproductive health in a population of first year college students.
Phase 1 will involve a minimum of 1-2 visits, and completion of surveys about your general health, exercise and nutrition history, eating behaviors and attitudes, stress, and reproductive health, as well as cognitive testing and hair sampling. For those who qualify, Phase 2 will involve approximately 4 additional visits. Each visit will be about 2 hours. The visits include completion of surveys about general health, exercise and nutrition history, eating behaviors and attitudes, stress, and reproductive health, as well as cognitive testing and physiological measurements including blood and hair sampling, and tests of metabolism. Study participation will last at minimum about 1 week, and at maximum completion of Phase 1 and Phase 2 will occur over the course of a full academic year.
$25 per visit, up to $75
Age 18-25 Years
BMI 16.5-30 kg/m2
No apparent metabolic, endocrine, or musculoskeletal disease.
Serious or chronic health condition (including thyroid illness, metabolic disease)
Unwilling to adhere to study protocol
Lactating
Does not speak English or are unable to give consent
Penn State SELF - Student Engagement, Learning and Flourishing
Substance misuse is a leading national problem, with young adults at high risk. We aim to develop a university resource that elucidates biobehavioral underpinnings of problematic student substance use at University Park campus. This initiative would inform services needed, provide engaged learning opportunities, connect with faculty, and catalyze high-impact, interdisciplinary research. In addition to this primary rationale, this study will allow us to capture detailed information about other critical student experiences such as food and housing insecurity, experiences of discrimination, and daily health practices to prevent the transmission of COVID-19. Participants will be asked to take a baseline survey followed by a 21- daily diary protocol (brief 5 minute survey each day for 21 days. For more information or to register interest in participating please see: https://projectself.psu.edu/register-your-interest/
Enrolled at UP
18-24 years old
Part-time students
Students located in the EEA
Older than 24
No graduate students
Driver Training on the Advanced Driving Assistant System
This research aims to study the training knowledge that is essential for drivers to use Advanced Driving Assistant Systems safely and properly and identify the optimal training approaches.
If you participate in the first experiment, you will receive training of the in-vehicle system via videos and manuals, complete a driving task on the driving simulator, and answer questions from questionnaires. If you participate in the second experiment, there will be two visits. In the first visit, you will receive training via watching and interacting with online videos, watching an experimenter operating ADAS at the test track, or practicing the functions of ADAS in a vehicle at the test track. The functions in the training include adaptive cruise control, lane-keeping assistance, and Highway Driving Assist. In the second visit, you will complete a driving task on the driving simulator and answer questions from questionnaires.
$30 for experiment1 and $60 for experiment 2
Being fluent in English
Have a valid driver license for at least one year
have normal vision or corrected vision only wearing contact lenses
Respect and Satisfaction in Same-Sex Romantic Relationships
The purpose of this study is to expand on previous research looking at respect and relationship satisfaction among heterosexual relationships and compare it to that of same-sex relationships to find where they are similar or different. Participants will complete self-report measures regarding their romantic relationships, including respect toward partner, satisfaction, and attitudes toward love. 30 minutes will be required for the study.
Daily Thought Monitoring Study for Anxiety and Depression
This study aims to assess the relations among our daily thought patterns, positive emotions, everyday experiences, and cognitive functioning abilities. Eligible participants will complete a series of online questionnaires, a short 15- to 25-minute psychological interview, and brief cognitive functioning tests at Day 1 and Day 16. All visits will occur via Zoom. In between study visits on Day 1 and Day 16, they will be prompted to complete smartphone-delivered assessments of cognitive functioning, symptoms, and experiences for 14 days, 5 times a day. This is important to inform clinicians and researchers on how best to develop effective digital mental health therapies.
During Day 1, participants will undergo a brief 15- to 25-minute clinical interview over Zoom. After the clinical interview, if participants meet the study eligibility criteria, we will continue with the procedures outlined below. Otherwise, if they are ineligible for the study, we will mention that this study is not suitable for them and provide the contact of mental health treatment services. Eligible participants will then conduct a series of self-report questionnaires and performance-based cognitive functioning tests for the next 35 minutes. Participants will then complete a series of 14-day brief ecological momentary assessments administered on their smartphone five times a day, for 14 days. Last, participants will return for a 35- to 45-minute visit on Day 15 to complete a series of self-report questionnaires and performance-based cognitive functioning tests.
15
Owns an Android or iPhone
Fluent in the English language
Scores on self-report questionnaires suggest person does or does not struggle with depression and/or anxiety
Pregnant women will be allowed to participate
Unable to consent
Younger than 18 years of age
Reports struggling with suicidal thoughts
Judged to have alcohol, substance use, and/or eating disorder
Attention and Emotional Development in Children
Children with attention problems often feel anxious or worried, and likewise, children who are anxious or worried often have problems with attention. We are looking for children aged 8-12 who may or may not have problems with attention or anxiety to help us understand what happens in the brain that could explain why. You will receive up to $100 gift card for your participation, and informal clinical feedback on your child.
Two in person visits of 2 hours each to the University Park campus, scheduled at the participant(s) convenience
$100
History of seizures or photosensitive epilepsy
Study Driver Characteristics in Mixed Traffic with a Driving Simulator
This is a driving simulator behavioral study. This study aims to investigate drivers' subjective feelings and driving performance in mixed traffic shared by automated vehicles and human-driven vehicles.
This study aims to investigate the effects of drivers’ driving style and automated vehicle penetration rate on drivers’ subjective feelings and driving performance in mixed traffic shared by automated vehicles and human-driven vehicles. There will be one in-person visit for the experiment. This experiment involves driving on a driving simulator and filling out several questionnaires.
$15/hour
Have a valid US driver license for at least one year
Have normal vision or corrected vision only wearing contact lenses
Advanced fMRI Study on the Functional Abnormality of BNST in Anorexia Nervosa Restricting-type
This research is being done to better understand how certain parts of the brain may react differently in people who have a particular eating disorder, anorexia nervosa, which may help us understand why they respond to food in the way they do. This may help us design more effective treatments for people with anorexia nervosa.
You will complete a package of surveys for personality, psychopathology, an evaluation of taste functions, and an MRI/fMRI examination.
Up to a total of $100.
Anorexia nervosa restricting type patients
Healthy volunteer with normal body weight
Right-handed
Fluent in written and spoken English
Pregnancy or breastfeeding
History of diabetes, substance abuse, head trauma
Allergy to milk and milk products
Cannot have MRI due to claustrophobia or specific implants
Audio-based mental health intervention study
This study tests the effect of an audio-based mental health intervention for symptoms of depression. Participants will be asked to listen to an audio program and perform exercises to support their mental health as suggested by the program. Participants will be asked to complete questionnaires about their depression and related mental health symptoms at pre-intervention, mid-intervention, post-intervention, and follow-up.
The study takes place over five total weeks, with four survey sessions (the first two of which are live on Zoom), and two weeks of brief daily surveys. Detailed information is below.For the first day, participants would be asked to complete Visit 1, which involves an interview, listening to a mental health audio program, and completing surveys. One week later, participants would be asked to complete Visit 2, which involves listening to another mental health audio program and completing surveys. One week after that, participants would be asked to complete Visit 3, which involves completing surveys. Three weeks after that, participants would be asked to complete Visit 4, which involves completing surveys. For the week following Visits 1 and 2, participants would also be asked to complete daily surveys.
Up to $40
Moderate or higher depression symptoms as indicated by survey and interview
Score below moderate depression symptom range in survey and/or interview
Drawing and Anxiety Study Phase 2
This study will test the efficacy of novel guided drawing activities for reducing anxiety in young adults
For this study, your teen will be asked to in a 90 minute in-person lab visit. Cardiac data will be recorded as your teen engages in a drawing activity. Your teen will also answer questionnaires during the visit and again approximately one week later, online via Qualtrics. This final questionnaire will take approximately 30 minutes to complete.
$25
Youth must be able to speak, understand and read English.
2.Youth who cannot speak, understand, and read English.
The association between perceived parenting styles, intolerance of uncertainty, and anxiety among young adults
This study aims to understand the association between young adults' perceived parenting, intolerance of uncertainty, and trait anxiety. Participant will be asked to complete a questionnaire that aims to answer the environment and parenting beliefs around which they were brought up, and if they face stressors and anxieties associated with them. This is a correlational study
Geographical location: USA
All genders
All ethnicities
Individuals over 34 years
Individuals residing outside USA
Investigation of Digital Media Use, Anxiety, and Biobehavioral Emotion Regulation in Adolescents
Over the past few decades, the social world of teens has been transformed by the use of digital technology. This study will examine associations between digital media use and emotions in adolescents' daily lives.Youth and their parent will complete questionnaires and semi-structured clinical interviews regarding the youth’s emotions, social experiences, and possible anxiety symptoms. For 10 consecutive days, youth will complete one computerized task once per day and four mini questionnaires via the Wear-It app on the youth's mobile device.Some youth will also participate in a lab visit that will last approximately two hours. Six months later, all youth will be asked to repeat one computerized task once per day and four mini questionnaires via the Wear-It App on the youth's mobile device.One year after enrollment, participants will complete final questionnaires, interviews, one computerized task once per day and four mini questionnaires via the Wear-It App on the youth's mobile device. Some youth will also participate in a lab visit that will last approximately two hours.
Over the past few decades, the social world of teens has been transformed by the use of digital technology. This study will examine associations between digital media use and emotions in adolescents' daily lives.Youth and their parent will complete questionnaires and semi-structured clinical interviews regarding the youth’s emotions, social experiences, and possible anxiety symptoms. For 10 consecutive days, youth will complete one computerized task once per day and four mini questionnaires via the Wear-It app on the youth's mobile device.Some youth will also participate in a lab visit that will last approximately two hours. Six months later, all youth will be asked to repeat one computerized task once per day and four mini questionnaires via the Wear-It App on the youth's mobile device.One year after enrollment, participants will complete final questionnaires, interviews, one computerized task once per day and four mini questionnaires via the Wear-It App on the youth's mobile device. Some youth will also participate in a lab visit that will last approximately two hours.
$495
Speak, write and read English
Must reside and participate from the US
Neurological disorders (ie, Autism, seizures)
Youth of parent not between 14-16.9 years of age
Those not residing in or participating from the US
Strengths, Outcomes, Adversity, and Resilience in College-Aged Childhood Cancer Survivors: The PSU SOAR Study
The purpose of this study is to analyze the strengths, outcomes, adversity, and resilience, as indicated by self-reported experiences in college students who may or may not be childhood cancer survivors. We are asking college students aged 18-23 years attending 4 year universities in the United States to report on their childhood health experiences and their current mental, physical, and social well being during college using a confidential survey. We plan to recruit students who have or have not had a childhood history of cancer and will also ask questions about their demographic information and health habits.
The participants will be asked to complete a confidential online survey that will take 10-15 minutes to complete.
Participants are eligible to earn a $75 Amazon gift card through a random drawing that they can choose to enter after submitting their survey responses
College student attending 4 year university
English as primary language
Not attending a 4 year university
Does not have English as primary language
Abstract Reasoning, Decision Making and Social Judgment as Markers of Frontotemporal Lobar Degeneration (FTLD) in Midlife in Juvenile Myoclonic Epilepsy (JME)
This study will look for emerging patterns of Frontotemporal Lobar Degeneration (FTLD), an early onset dementia, in Juvenile Myoclonic Epilepsy (JME). JME is a type of epilepsy that usually begins in adolescence and is known to be associated with disturbances of higher-level reasoning, mood and personality. JME patients are often managed by family physicians, rather than epilepsy specialists; with little known about aging with JME. We think that JME patients will demonstrate a pattern of executive dysfunction that is consistent with consensus criteria for FTLD, characterized by declines in abstract reasoning, judgment, and verbal problem solving, as well as behavior. We also think that there will be an inverse relationship between apathy and conscientiousness. We plan to obtain this information by formal cognitive testing of non-demented JME patients over a period of 2 years, at 6-month intervals, to look for progression of symptoms. Loved ones/caregivers will complete informant questionnaires about patient's mood and personality at the beginning of the study and at 6 month intervals throughout the duration of the 24 month study. We will also include loved one/caregiver cognitive testing at the beginning of the study to obtain healthy information for comparison to patient's findings. Our objectives are to characterize the executive functioning profiles of JME in midlife, taking into account cognition, mood, personality, nutritional status and lifestyle. The information obtained may contribute to better care of JME patients prior to midlife and throughout the course of aging.
Visit 1 for both patient and healthy caregiver participants will involve administration of the JME Virtual Visit Protocol via PSH Zoom. Participants will have completed their REDCap questionnaires prior to the visit to the research coordinator, who will be conducting the assessment. Visit 2-5 for patient participants will involve administration of the JME Virtual Visit Protocol via PSH Zoom. JME participation consists of 5 virtual visits with the study’s research coordinator, lasting approximately two hours each, for completion of standardized tests of problem-solving, thinking, and concentration, as defined above. Caregiver healthy control participation consists of 1 virtual visit with the study’s research coordinator, lasting approximately two hours, for completion of standardized tests of problem-solving, thinking, and concentration, as defined above. Remaining participation involves completion of objective inventories providing a caregiver perspective of the patient participant’s mood and behavior at 6-month intervals, within the 24 month time frame of the study.
Primary language English
age 35 - 65
Mainstream Education
Loved one or caregiver to complete questionnaires
Cardiac conditions affecting cognition
Other medical conditions affecting cognition,e.g.,hypoglycemia
Hospitalization for major depressive disorder within the past year
No available loved one or caregiver to complete questionnaires