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Predicting Concussion Outcomes with Salivary miRNA
The purpose of this study is to identify changes in salivary micro ribosomal nucleic acid (miRNA) expression that are predictive of symptom duration and severity following mild traumatic brain injury (mTBI) in children.
The primary endpoints of this study are as follows:
1) Characterization of brain-related miRNA in the saliva of 250 children with mTBI and 200 age- and gender-matched controls between the ages of five and twenty-three years.
2) Identification of a set of salivary miRNAs that is predictive of duration and severity of mTBI symptoms.
Brennen Harding at bharding@pennstatehealth.psu.edu or 717-531-5656
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NCT02901821
Children's Health, Neurology, Sports Medicine