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A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Omecamtiv Mecarbil on Mortality and Morbidity in Subjects With Chronic Heart Failure With Reduced Ejection Fraction

The study is looking to find out more about how an investigational study drug called omecamtiv mecarbil works in people with heart failure. Omecamtiv mecarbil is also known as AMG 423. Omecamtiv mecarbil is an investigational medicine that increases the heart’s ability to pump.
18 year(s) or older
This study is NOT accepting healthy volunteers
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Inclusion Criteria:
Hospitalized or an urgent ER visit for heart failure within the last 12 months.
Exclusion Criteria:
Age greater than 85 at the time of first study visit
Require dialysis
Require use of oxygen
Cancer requiring treatment within the last 5 years (Some exceptions may apply)
Unable to swallow pills
Heart & Vascular
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Hershey, PA