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Application of graph theory to both resting-state and task-based fMRI data to uncover brain-behavior relationships related to therapy outcomes in aphasia
This project will use fMRI to examine changes in the brain related to behavioral therapy outcomes in persons with aphasia. We aim to recruit twenty persons with aphasia. Each participant will receive 4 MRI scans. Between scan 1 and scan 2, no therapy will be provided (10 week break). Between scan 2 and scan 3, ten weeks of word finding therapy will be provided. Between scan 3 and scan 4, no therapy will be provided (10 week break). The therapy used is abstract word retrieval training. The results of this project will help inform rehabilitation practices in aphasia.
There will be 4 fMRI scans. After the first and third fMRI scans, there will be an assessment. After the second fMRI scan, there will be 10 weeks of treatment.
$460
Yes
Chaleece Sandberg - at cws18@psu.edu or 814-863-2006
Communication Sciences and Disorders (UNIVERSITY PARK)
All
18 year(s) or older
NCT03550092
STUDY00009502
Inclusion Criteria:
Diagnosis of aphasiaSustained stroke at least 6 months ago
Right-handed
Native English speaker
Completed at least a high school education
Exclusion Criteria:
History of neurodegenerative disease (e.g., Alzheimer's)History of other acquired neurological disorder (e.g., TBI)
History of developmental disorder (e.g., autism)
History of psychological disorder (e.g., schizophrenia)
Unsafe to receive MRI (e.g., pacemaker)
Neurology, Language & Linguistics