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Assessment of Endothelial Function in Post-Menopausal Women with Depression

The goal of this project is to understand the contribution of depression on blood vessel function in post-menopausal women, a population at heightened risk for cardiovascular disease. Currently, little is known about the combined impact of depressive symptoms and the effects of reproductive aging on blood vessel function. As such, there is a greater need to characterize blood vessel function in post-menopausal women with depressive symptoms. Participants depressive symptoms will be assessed and non-invasive vascular measures will be performed.
Jigar Gosalia at or 814-863-3182
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Post-menopausal women who are at least 1 year removed from their final menstrual period and between the ages of 50 and 80
Postmenopausal women with moderate to severe depression
Non-depressed post-menopausal women are needed as well for control group comparisons
Free from blood-pressure lowering medication and lipid lowering medication
Exclusion Criteria:
Individuals with any overt cardiovascular, metabolic, hematologic, pulmonary, renal, musculoskeletal, and/or neurological disease(s).
Users of any tobacco and/or nicotine products (smokers, chewing tobacco, nicotine-containing patches/gum, smokeless cigarettes)
Individuals taking hormone therapy
Individuals with a BMI > 35
Heart & Vascular, Mental & Behavioral Health, Women's Health
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State College, PA