This research is being done to compare the differences in traditional cigarette reduction between smokers who receive a 0 mg/ml nicotine e-cig and those who receive a 58 mg/ml nicotine e-cig. We will also compare differences between the groups for changes in breathing (lung function), heart activity (EKG), blood pressure, and smoking-related chemicals found in urine.

The study consists of 3 in-person visits at the Milton S. Hershey Medical Center. At the first visit, eligibility will be confirmed, then participants will be provided with an electronic cigarette and asked to use the electronic cigarette as a complete replacement for their cigarettes, starting the very next day. Participants are followed up 3 and 6 weeks later.

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