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1 Study Matches

Measuring Neuroadaptations in Response to Very Low Nicotine Content Cigarettes

For this study, 75 smokers will be randomly assigned to smoke research cigarettes with a very low or normal nicotine content. Participants will complete functional magnetic resonance imaging (MRI) scans at 2 in-person study visits to help us better understand how reducing nicotine intake affects decision making and reward processing.
Brianna Hoglen at
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Smoke greater than or equal to 5 cigarettes per day
21-60 years old
>1 year daily smoking
Live local for next 3 months
No plans to quit smoking in next 6 mos.
Exclusion Criteria:
Regular use of non-cigarette tobacco products
MRI safety contraindications
Unstable or significant medical conditions
smell dysfunction
Addiction & Substance Abuse, Smoking, Vaping, Nicotine and Tobacco
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Hershey, PA