Search Results

Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.

1 Study Matches

Age Comparisons of Exercising Muscle O2 Supply in Healthy Adults: Effects of Esmolol Infusion

This research is being conducted to determine how oxygen extraction within exercising muscles is altered in younger and older women when beta-1 receptors (receptors that contribute to the rise in heart rate with exercise) are temporarily blocked through a medication infused into an arm vein. The findings will help us understand how aging affects the regulation of oxygen supply to working muscles is regulated with normal aging.

There will be 3 in person visits. Visit 1) Subjects will undergo a physical and one blood draw in the Clinical Research Center and then perform two recumbent cycling exercise trials on a stationary bike. Visit 2) Subjects will undergo a DXA scan and then perform two recumbent cycling exercise trials. Visit 3) Subjects will have an IV catheter inserted into an arm vein. They will then perform two recumbent cycling exercise trials. During one trial the will receive esmolol via the IV catheter and during the other they will receive saline via the IV catheter (random order).


Matthew Studinski - at or 715-498-8093

18 year(s) or older
This study is also accepting healthy volunteers
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Premenopausal women (18-35 years)
Postmenopausal women (55-70 years)

Exclusion Criteria:
Users of any tobacco and/or nicotine products
Individuals taking hormone therapy
Pregnant or lactating
Individuals with any over cardiovascular, metabolic, hematologic, pulmonary, renal, musculoskeletal, and/or neurological disorders
Heart & Vascular
I'm interested
Share via email
See this study on
Show 1 location

Study Locations

Hide all locations
Location Contacts
State College, PA ,