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Age Comparisons of Exercising Muscle O2 Supply in Healthy Adults: Effects of Esmolol Infusion

This research is being conducted to determine how oxygen extraction within exercising muscles is altered in younger and older women when beta-1 receptors (receptors that contribute to the rise in heart rate with exercise) are temporarily blocked through a medication infused into an arm vein. The findings will help us understand how aging affects the regulation of oxygen supply to working muscles is regulated with normal aging.
Matthew Studinski at mxs1455@psu.edu or 715-498-8093
Female
18 year(s) or older
This study is also accepting healthy volunteers
NCT04181606
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Inclusion Criteria:
Premenopausal women (18-35 years)
Postmenopausal women (55-70 years)
Exclusion Criteria:
Users of any tobacco and/or nicotine products
Individuals taking hormone therapy
Pregnant or lactating
Individuals with any over cardiovascular, metabolic, hematologic, pulmonary, renal, musculoskeletal, and/or neurological disorders
Heart & Vascular
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Location
State College, PA