Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.
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Study Matches
Assessment of nocturnal hypoventilation in amyotrophic lateral sclerosis
The overall goals of this study are to identify how measurement of carbon dioxide during sleep can improve recognition of respiratory distress in neuromuscular disease and thus improve timely access to respiratory therapies which prolong survival.
Subjects in this study will participate for up to one year, during which their carbon dioxide levels will be measured in clinic and in their homes during sleep.
Diagnosis of amyotrophic lateral sclerosis 18 years of age or older. Plan to be followed up in person in the Hershey ALS Clinic for the next 12 months. Experiencing early respiratory change. Able to perform or have assistance performing home CO2 measurements.
Exclusion Criteria:
In hospice or in active transition to hospice Use of any type of non-invasive ventilation, except in the case of CPAP for obstructive sleep apnea, or have a tracheostomy Use of diaphragm pacer Pre-existing pulmonary disease requiring supplemental oxygen for any portion of the day or night