Hand Action and Perception in Parkinsons Disease
The purpose of this research study is 1.) to determine if Parkinson’s Disease (PD) causes changes in the way that people sense the movements of and forces produced by their bodies, and to connect any of these changes in sensation to changes in the brain, and 2.) to identify how changes in movement might come from different parts of the nervous system. This study will use a combination of electromyography, via electrodes placed on the skin, and finger force recordings to infer how PD effects patients' sense of force production, and the neural mechanisms underlying this change.
This study requires a single in-person visit and will use adhesive skin sensors on the forearms to measure muscle activity while subjects press on sensors which record force levels. Subjects will be asked to match force levels between hands and to move an on-screen cursor into a target.
No history of earning disability, neurodevelopmental disorder, seizures, multiple concussion (> 3), cerebrovascular disease, brain tumor, hydrocephalus, or any CNS disease other than PD.
No present carpal tunnel syndrome, cervical myelopathy, brachial plexopathy, hand pain, or another neuromusculoskeletal disorder affecting hand function
No history of alcohol and/or drug abuse.