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Effect of Nitrate Supplementation on Cerebrovascular function and Cognitive Function in Older Adults with Metabolic Syndrome

The aim of this study is to determine the impact of cardiometabolic disease risk factors on cognitive performance and brain vascular function, as well as, to see if beetroot juice supplementation can improve these outcomes and reduce risk of cognitive decline and brain vascular dysfunction that is seen with aging and disease.

Participants with and without high blood pressure, high cholesterol, and high blood sugar will be recruited. These are all considered cardiovascular disease risk factors. Individuals without multiple cardiovascular disease risk factors will have 2 visits and complete cognitive and blood vessel function assessments. There involves a blood draw in each visit. All study assessments are non-invasive. Total compensation is $30. Individuals with cardiovascular disease risk factors will have 5 total visits and complete cognitive and blood vessel function assessments. Additionally, participants will drink beetroot juice for 4 weeks to determine the potential health benefits on cognitive, blood vessel function, and metabolic health. There will involve blood draws and all assessments are non-invasive. Total compensation is up to $170.

$30 -170

DAVID PROCTOR
Jigar Gosalia - at jzg691@psu.edu or 516-816-1654
 

All
18 year(s) or older
This study is also accepting healthy volunteers
NCT05532423
STUDY00020830
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Inclusion Criteria:
Age 55 - 75
high blood pressure and/or high cholesterol and/or high cholesterol
the above criteria does not apply for the control group

Exclusion Criteria:
Smoking
Severe visual impairment
Individuals with any overt cardiovascular, hematologic, pulmonary, renal, musculoskeletal, and/or neurological disease(s)
Food & Nutrition, Heart & Vascular, Women's Health
Experimental drug compared to a placebo/”sugar pill”
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See this study on ClinicalTrials.gov
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Location Contacts
State College, PA ,