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Study matches: 133

Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.


Natural History Study of the Development of Type 1 Diabetes

Natural History Study of the Development of Type 1 Diabetes
Patricia Carper at pcarper@pennstatehealth.psu.edu or 717-531-5656
All
Not specified
This study is also accepting healthy volunteers
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Inclusion Criteria:
aged 1-45 years and a sibling, offspring, or parent of an individual with type 1 diabetes
aged 1-20 years and a niece, nephew, aunt, uncle, grandchild, cousin, or half sibling of an individual with Type 1 diabetes
willing to have blood drawn
Exclusion Criteria:
Have previous or current use of medications for the control of hyperglycemia
Currently use immunosuppressive or immunomodulatory therapies
Has diabetes
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NCT00097292
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Location
Hershey, PA

Cognitive Processes in Bilinguals: ERP Studies

In this study, we examine how people read words and sentences in their first language or in their second language (if they speak or are learning a second language). We use behavioral (e.g., button presses or recording people's eye movements) or neuroscience methods (e.g., recording of brain waves using electrodes) to collect our data. Participants receive monetary compensation for their participation. I hope you contact us to participate!
Paola Dussias at pdussias@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Adults 18 years or older
Right handed
Normal or corrected-to-normal vision
No history of neurological disorders or language disorders
Participants will be recruited from the following language groups: monolingual English speakers; bilinguals whose native language is English; native speakers of Spanish whose second language is English
Exclusion Criteria:
Children under the age of 18
Left handed or ambidextrous
Uncorrected vision
A history of neurological disorders or language disorders
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N/A
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Location
State College, PA

Establishing a Normal Database for Comparison to Specialized Populations; Oxygen consumption

This study will examine the cardiovascular and respiratory responses to exercise testing on a treadmill, stationary bike or arm bike to determine overall aerobic fitness capacity. This will contribute to a database of healthy adults to compare to persons with disabilities.
Kristin Slavoski, MS at PMR_research@pennstatehealth.psu.edu or 7175310003 x283816
All
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Healthy Adults
Exclusion Criteria:
Known cardiovascular, pulmonary or metabolic disease
Current orthopedic injuries
Claustrophobia
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N/A
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Location
Hershey, PA

Characterizing the gait mechanics of adolescents

The purpose of this study is to characterize the effect of weight on walking and running in adolescents. A better understanding of the mechanical consequences of weight will allow us to design training programs to minimize injuries and improve participation in physical activity.
Allison Singles at ara5093@psu.edu or 610-396-6152
All
Younger than 18 years old
This study is also accepting healthy volunteers
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Inclusion Criteria:
Between 12 and 16 years old
Exclusion Criteria:
Any major injuries or surgeries
Cannot walk or run independently
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N/A
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Study Locations

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Location
Reading, PA

PIRE II (Translating cognitive and brain science research to the field and education settings): How Children and Adults Understand Sentences

The focus of the research being conducted asks how bilingual Spanish-English children who are growing up in a Spanish-speaking environment (Granada) but who attend a private school in which they are instructed solely in English, process syntactic ambiguity in Spanish and English. The study is motivated by two questions that the parents of these children have concerning their children’s language development. These are: (1) Whether their children are learning to process English natively; and (2) What effect learning English has on the children’s ability to process Spanish. In this respect, the results have the potential to inform decisions about bilingual education ( translation al implication). In addition to testing bilingual Spanish-English children in Granada, we will also test: bilingual Spanish-English children in the US; bilingual Spanish-English adults in the US; bilingual Spanish-English adults in Spain; monolingual Spanish adults; monolingual English adults; monolingual Spanish children; monolingual English children to serve as our control groups.
Paola Dussias at pdussias@psu.edu
All
Not specified
This study is also accepting healthy volunteers
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Inclusion Criteria:
Monolingual adults whose native language is English OR Spanish-English bilingual adults
Be 18 years or older (adults)
Have normal to corrected vision
Monolingual children whose native language is English OR Spanish-English bilingual children
Be between 4-14 years old (children)
Exclusion Criteria:
Children who are not monolingual native English speakers or who are not Spanish-English bilinguals
Children outside of the target age range
Adults who are under the age of 18
Children who are not typically developing
Monolingual adults whose native language is not English or adults who are not Spanish-English bilingual speakers
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N/A
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Study Locations

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Location
State College, PA

Parental Stress and Coping Post-NICU Discharge: Perceptions of Daily Stress and Psychobiological Patterns of Response to Stress Challenge

Parental stress levels following discharge from the neonatal intensive unit (NICU) can have impacts on mental health and relationship functioning. The current practice and understanding of Family-centered NICU care often does not address interventions to facilitate parental means to cope with this stress, be it through religious/spiritual means or traditional forms of coping, both of which are tied to their babies’ functioning outside of the NICU. Thus, parental experiences of stress as assessed through self-perceptions and biological and behavioral indicators of stress and coping strategies is an important first-step in future development of a psychospiritual intervention, which is thus far lacking in family-centered NICU care.  
Fumiyuki Gardner at fgardner1@pennstatehealth.psu.edu or 717-531-0003 x286280
All
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Parent of a former preterm infant hospitalized in NICU within the past 12 months with parental custody of the infant
Fluent in written and spoken English
Exclusion Criteria:
Chronic illness impacting cardiovascular or autonomic stress measurement (autoimmune disorders- e.g., Lupus, RA, Crohn’s disease)
Advanced cardiovascular disease (e.g., CHD, CHF, arrhythmia, pacemaker, history of MI)
Individuals with endocrine disorders impacting stress hormonal measures (e.g., Cushing’s Disease, Addison’s Disease, IDDM)
Mental illness (e.g., schizophrenia, psychosis, panic disorder)
Pregnant women
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N/A
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Study Locations

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Location
Hershey, PA

Improving Autism Screening with Brain-Related miRNA

The central aim of this project is to characterize the expression of exosomal microRNA (miRNA) in children with autism spectrum disorder (ASD). We propose to measure the expression of extracellular miRNA in children with ASD. Expression levels of miRNA from blood and saliva will be compared between children with autism and normally developing controls. The goal of this study will be to identify genetic regulatory mechanisms involved in ASD and provide potential biomarkers for diagnostic screening.
Julie Vallati at jvallati@pennstatehealth.psu.edu or 7175313049
All
Younger than 18 years old
This study is also accepting healthy volunteers
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Inclusion Criteria:
Age: 24 Months
•6 Years
Confirmed Diagnosis of Autism or Developmental Delay or Healthy Child
Exclusion Criteria:
Wards of the state
Underlying Seizure Disorder
Underlying Genetic Disorder
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NCT02712853
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A Pilot Trial of Subtyping Pediatric Conduct Problems by the Presence of Severe Persistent Irritability and Callous Unemotional Traits

Youth with irritable and aggressive behaviors, or conduct problems, are thought to be sensitive to rewards and insensitive to punishments. Parents and children will complete rating scales and computer tasks that will assess for sensitivity to rewards and punishments. This study will help to target interventions for treating children with conduct problems.
Sara Mills at smills1@pennstatehealth.psu.edu or 17175310003285968
All
Younger than 18 years old
This study is also accepting healthy volunteers
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Inclusion Criteria:
Ages 7--12 years
Elevated degree of conduct problems
IQ greater than 80
Exclusion Criteria:
Diagnosis of an intellectual disability, psychosis, ASD, or a pervasive developmental disorder
Sever suicidality
Visual or hearing impairments
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N/A
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Location
Hershey, PA

Memory and Aging Study

This research is being done to find out more about changes in the brain as we age and to determine if MRI, genetic (DNA) variations, and neuropsychological tests can be used to evaluate memory loss and cognitive impairment.
Lauren Spreen at lspreen@pennstatehealth.psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Diagnosis of Alzheimer's disease
Diagnosis of Mild Cognitive Impariment
Normal Controls-Cognitively normal functioning
Exclusion Criteria:
Neurological disease (e.g., stroke, tumor, Parkinson's disease, etc.)
Psychiatric disorder (e.g., bi-polar, schizophrenia, etc.)
History of chemotherapy
Presence of a cold or viral infection
Presence of a pacemaker, aneurysm clips, or any metal in body
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N/A
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Study Locations

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Location
Hershey, PA

Development of a caregiver-report instrument to assess child behavior.

It is commonly agreed that school-aged children display observable attachment behavior, although it is difficult to elicit in laboratory tasks. However, caregivers will observe this behavior on a regular basis when it occurs and can provide useful information regarding the structure and function of that behavior. The goal of the current proposal is to define a potential caregiver-reported instrument assessing early school-age children’s attachment behavior and collect initial data sufficient to examine the factor structure and reliability of the measure. Data collection will utilize anonymous online survey methodology and recruit through schools and preschools.
Brian Allen at ballen1@pennstatehealth.psu.edu or 7175314100
All
Not specified
This study is also accepting healthy volunteers
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Inclusion Criteria:
Adult caregiver of a child between the ages of 4 and 8
Adult caregiver is at least 18 years of age
Adult caregiver is the primary caregiver of the child.
Exclusion Criteria:
Child has an autism spectrum disorder, intellectual disability, or other developmental delay.
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N/A
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Tongue movement in adults with motor speech disorder

Tongue movement in adults with motor speech disorder
Elizabeth Rodriguez at ezr16@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
be a native speaker of American English
have normal hearing
between 18 and 40 years of age
have no known speech, language, learning or neurological disorders
have very little experience in communicating with people that have motor speech disorders
Exclusion Criteria:
younger than 18 years of age; older than 40 years of age
Not a speaker of American English only
With hearing impairment
have neurologic and/or speech/language disorders
have extensive experience in communicating with people that have motor speech disorders
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N/A
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Study Locations

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Location
State College, PA

Role of angiotensin II and inflammation in persistent vessel dysfunction following preeclampsia

The purpose of this study is to determine what contributes to blood vessel damage during and immediately following a preeclamptic pregnancy. To do this, we examine blood vessel function in the small vessels in the skin. Understanding what contributes to these impairments may lead to better treatments and/or prevention strategies for vessel dysfunction in women who have or had preeclampsia. Two groups of subjects will be enrolled in this study: women who have delivered within 1 year and who have had a preeclamptic pregnancy diagnosed by their obstetrician, and women who have delivered within 1 year and did not have preeclampsia.
Susan Slimak at sks31@psu.edu or 814-863-8556
Female
18 year(s) or older
This study is also accepting healthy volunteers
Hide eligibility criteria
Inclusion Criteria:
had a baby in the last 12 months
had preeclampsia or did not have preeclampsia
Exclusion Criteria:
had gestational diabetes
history of hypertension prior to pregnancy
current tobacco use
currently pregnant
currently taking medication to lower cholesterol
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N/A
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Study Locations

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Location
State College, PA

Exploring Parental Influence in Youth Disability Sport Participation

We are conducting an online survey study for parents of children with disabilities that explores their perceptions of participation in disability sport within their communities.
Courtney Jasiulevicius at cmj5308@psu.edu or 8138464145
All
18 year(s) or older
This study is also accepting healthy volunteers
Hide eligibility criteria
Inclusion Criteria:
has a child with a physical disability or sensory disability
has a child that is enrolled in a disability or adapted sport program
has a child between the ages of 10 and 17
Exclusion Criteria:
does not have a child with a physical or sensory disability
does not have a child with a disability between the ages of 10 and 17
does not have a child that plays a disability or adapted sport
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N/A
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Cheese Consumption and Human Microvascular Function

The human body controls the amount of blood flowing through healthy blood vessels. The body performs this vital function by changing the diameter of the blood vessels. The way the body controls blood flow can be different with age and the presence of some diseases such as hypertension (high blood pressure). One of the first signs of a disease that affects blood vessels is a change in the function of the very small blood vessels (microcirculation) of the skin. Studying blood flow control in the skin’s blood vessels helps researchers to learn about the onset and effects of, and develop treatments for diseases that affect blood vessels. Dietary sodium can impair the function of the microcirculation in the skin. This study’s goal is to determine if and how natural cheese may protect against impairments in the function of the microcirculation caused by sodium in an otherwise healthy older people. We conduct a study in which participants eat cheese (6 servings/day) or no cheese during a 7-day low-sodium or high-sodium base-diet. Our approach uses methods specific to the microcirculation to examine how sodium causes human microcirculation impairment and the potential protective effects of natural cheese. Also, we measure blood biomarkers and the function of larger blood vessels to examine the effects of cheese on overall vascular health.
Susan Slimak at sks31@psu.edu or 814-863-8556
All
18 year(s) or older
This study is also accepting healthy volunteers
Hide eligibility criteria
Inclusion Criteria:
Men and women (55-75 years)
Apparently healthy
Normal blood pressure
Non-diabetic (HbA1C <5.7%)
Exclusion Criteria:
Taking a drug that alters peripheral vascular control
Pregnant or Breastfeeding
Females taking contraceptives (pills, patches, shots, etc.) or hormone replacement therapy
Use of nicotine use (e.g. smoking, chewing tobacco, etc.)
Known allergy to latex or investigative substances
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NCT03376555
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Location
State College, PA

Assessing Dietary Requirements in Relation to Resting Metabolic Rate in Spinal Cord Injury

This research is being done to examine the relationship between body composition, metabolism, and dietary needs in people with Spinal Cord Injury.
Slavoski at PMR_research@pennstatehealth.psu.edu or 717-531-0003
All
18 year(s) or older
This study is also accepting healthy volunteers
Hide eligibility criteria
Inclusion Criteria:
C4-T4 Spinal Cord Injury greater than 12 months
Motor Complete (AIS A & B) spinal cord injury
<5% change in body weight over the past 12 months
Exclusion Criteria:
<22% body fat
Coronary artery disease
Type 1 Diabetes or insulin requiring Type 2 Diabetes
Hypothyroidism
Renal Disease
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N/A
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Location
Hershey, PA

Mechanisms of neurovascular dysfunction in psoriasis patients

The purpose of this study is to determine what leads to blood vessel and nervous system dysfunction and the increased risk of cardiovascular disease in adults with psoriasis. Psoriasis is an independent risk factor for cardiovascular disease, because cardiovascular disease and psoriasis share common underlying inflammatory causes. This study may lead to treatment and/or prevention strategies to reduce cardiovascular disease risk in psoriasis patients. We explore 1) changes in nitric oxide that could make the body less able to relax blood vessels and 2) changes in sympathetic nervous system function that may contribute to increased cardiovascular disease risk in psoriasis patients. We will investigate the effect of oral salsalate administration on neural and blood vessel function in adults with psoriasis. The study includes experiments that examine blood vessel function in small vessels in the skin and nerve activity in the leg.
Billie Alba at bka125@psu.edu or 814-863-8557
All
18 year(s) or older
This study is also accepting healthy volunteers
Hide eligibility criteria
Inclusion Criteria:
Men and women (18-65 years)
Apparently healthy
Exclusion Criteria:
Pregnant or Breastfeeding
Allergies to NSAIDs or aspirin
Bleeding disorders or history of gastrointestinal bleeding
Renal disease
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N/A
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Study Locations

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Location
State College, PA

Variation of muscle stiffness induced by blood pressure changes

Blood pressure is the amount of force created inside the arteries and veins, this force varies between a maximum and minimum value during the cardiac cycle. Blood pressure may affect mechanical properties of muscles (particularly the ones near arteries) due to the variation of internal force in the tissue. In order to accurately evaluate muscle stiffness, and to diagnose several cardiovascular diseases is necessary to describe the relationship between of blood pressure on muscle stiffness. The objective of this study is to quantify changes in lower-leg muscle stiffness using ultrasound shear wave elastography (SWE) in healthy subjects by changing intramuscular blood pressure (IMP) through changes in elevation of the leg, different body positions and using a blood pressure cuff around the thigh. Intramuscular pressure may also be measured through a needle inserted in the muscle (under local anesthesia)
Daniel Cortes at researchsubjects@mne.psu.edu or 814-863-3103
All
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Healthy subject between 18
•45 years old
Exclusion Criteria:
allergic reaction to ultrasound gels
cardiovascular diseases
diabetes
individuals who can easily bruise
pregnant women
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N/A
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Study Locations

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Location
State College, PA

Penn State Hershey Sitting and Health Study

This study aims to examine the effect of pedaling a compact elliptical device at the desk on employees' work productivity. This study also aims to evaluate the effect of different types of incentives on promoting desk-based pedaling.
Liza Rovniak at activitystudy@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
Hide eligibility criteria
Inclusion Criteria:
Penn State Hershey full time employee
Overweight or obese
Spend at least 5 hours per day sitting at a desk
Have eligible overweight/obese coworker who can do study together with you
18-70 years old
Exclusion Criteria:
Currently pregnant
Planned surgical or medical treatment that will prevent ability to complete study
Heart condition, or chest pain during physical activity
Planned travel or relocation during study period
Already have desk cycling device or treadmill at desk
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NCT03274635
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Location
Hershey, PA

Nasality characteristics in adults with motor speech disorder

The goal of this proposed study is to understand nasality characteristics in individuals with dysarthria (motor speech disorder) secondary to ALS. The research question the proposed study seeks to answer is how does the perception of speakers’ hypernasality relate to the severity of their dysarthria and their nasalance scores.
Elizabeth Rodriguez at ezr16@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
Hide eligibility criteria
Inclusion Criteria:
are 18-40 years of age
are a speaker of American English only
have normal hearing
have no neurologic and/or speech/language disorders
have very little experience in communicating with people that have motor speech disorders
Exclusion Criteria:
younger than 18 years of age; older than 40 years of age
Not a speaker of American English only
With hearing impairment
have neurologic and/or speech/language disorders
have extensive experience in communicating with people that have motor speech disorders
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N/A
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Study Locations

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Location
State College, PA

Replication of The Multi-Media Social Skills Project for Adolescents with Autism Spectrum Disorders

Replication of The Multi-Media Social Skills Project for Adolescents with Autism Spectrum Disorders
Michael Klemick at mklemick@pennstatehealth.psu.edu or 7175310003 x.284923
All
Younger than 18 years old
This study is also accepting healthy volunteers
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Inclusion Criteria:
Between 13 and 17 years of age or still enrolled in high school
A primary diagnosis of Asperger's Syndrome or high-functioning autism, as confirmed by the Checklist for Autism Spectrum Disorders (CASD; Mayes, 2012)
English as primary language spoken
Ability to fluently speak in full sentences
A verbal IQ of 85 or above on the Kaufman Brief Intelligence Test, Second Edition (KBIT-2; Kaufman & Kaufman, 1990)
Exclusion Criteria:
A significant language delay
Difficulty with aggression directed at peers
A primary thought disorder
A secondary disorder of anxiety or depression so severe as to prevent the individual's participation in the treatment
Low social motivation demonstrated through formalized assessment (SRS) and/or by responses given to screening interviews assessing treatment goals
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N/A
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Study Locations

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Location
Altoona, PA
Greater Philadelphia Area, PA
Greater Pittsburgh Area, PA
Hershey, PA
Wilkes-Barre/Scranton Area, PA

A Longitudinal Study To Identify Early Non-invasive Ocular Markers of Diabetic Complications

This is a human subject study looking at the complications arising in newly diagnosed diabetic patients using non-invasive measures, optical coherence tomography (OCT) and corneal confocal microscope (CCM), indicative of peripheral neuropathy and diabetic retinopathy. Through the use of these devices we would like to determine the onset of corneal nerve fiber alterations and retinal thinning in newly diagnosed diabetics. This information could help investigators find early and reversible biomarkers to target for therapeutic options.
Ellen Stoute at estoute@pennstatehealth.psu.edu or 717-531-4696
All
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Corrected visual acuity of 20/25 or better
Patients with diabetes must be newly diagnosed, withing the last 5 years
Diabetics must have initial HbA1c of greater than 6.5 or a fasting glucose of 126 or higher
Healthy controls must have HbA1c less than 6.5 or fasting blood glucose of 100mg/dl or less
Exclusion Criteria:
History of vitreous or retinal surgery
Lasix surgery
Previous ocular trauma
History of diabetic complications
Cataract surgery within 3 months of enrollment
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N/A
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Study Locations

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Location
Hershey, PA

Aging and Language

The purpose of this study is to investigate how language is organized in neurologically normal adults using magnetic resonance imaging (MRI) and behavioral measures. Our overarching goal is to characterize the behavioral and MRI responses associated with language production and language comprehension in older and younger adults, and to examine the relations between age, behavior, cognition, and neural factors.
Anna Eppes at aze23@psu.edu or 814-865-2912
All
18 year(s) or older
This study is also accepting healthy volunteers
Hide eligibility criteria
Inclusion Criteria:
Age over 18 years old
Native Monolingual English Speaker
Right-handed
Exclusion Criteria:
History of neurological injury or disease
Taking medications that affect the brain of blood flow
Contraindications to MRI (e.g., pacemaker)
Claustrophobia
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N/A
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Study Locations

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Location
State College, PA

Cyclic Variation in Micronutrient Concentrations and Plasma Volume in Reproductive-Age Women

In this study, we will examine how the menstrual cycle influences micronutrient concentrations in women of reproductive age. We will also examine how the menstrual cycle affects plasma volume in these women. Finally, we will assess the relationship between plasma volume and micronutrient concentrations among study participants. This study involves three visits to the Clinical Research Center (CRC) located in Noll lab, University Park. To participate, interested women will contact the study coordinator via phone or email and provide their name and phone number. A member from the PI lab will contact the interested participant to screen her for eligibility. If a participant is eligible, she will be scheduled to visit the CRC, where eligibility will be confirmed. To confirm eligibility, we will measure her weight, height, blood pressure and conduct a pregnancy test. If eligible, we will conduct hydration test, and measure body composition, then she will complete a short questionnaire about her pregnancy histories and health. She will then rest on bed for 15 to 20 minutes and the nurse will insert an IV to draw some blood ~15mL. Then the nurse will inject her with a small amount of a green dye followed by a series of blood draws (total ~15mL) within the next 5 minutes. She will relax on the bed or sit on a chair for 15 minutes to be monitored by the nurse, to be sure that she is okay. Then we will provide her with a home-based fertility monitor to be used to track her menstrual cycle. We will instruct her on how to use her urine sample to track daily changes in some targeted reproductive hormones during the cycle. The results are displayed in a simple to read format from the monitor. We will use the readings from this monitor to schedule visit 2 (~ day 12 of her cycle). After visit 2, the participant will conduct a few more urine test at home and the results of those tests will be used to schedule her final last visit (~ day 21 of her cycle). On the 2nd and 3rd visits, we will again measure her weight, height, blood pressure and conduct pregnancy to confirm that the participant is still eligible. If we confirm she is still eligible, we will complete the rest of the measurements as in visit one. Blood samples at each visit will be processed and stored at -80C until the data collection is completed. Plasma samples will be processed same day to determine the subject’s plasma volume.
Sixtus Aguree at sua204@psu.edu or 814-867-5938
Female
18 year(s) or older
This study is also accepting healthy volunteers
Hide eligibility criteria
Inclusion Criteria:
Female
18 to 44 years of age
General good health (does not have a known, ongoing health condition/medical issue that requires regular monitoring by a doctor or regular visits to the hospital)
BMI 18.5-24.9 kg/m2
Regular menstrual cycle (26-35 days) & currently non-pregnant
Exclusion Criteria:
Known allergy to shellfish or iodine
Currently using hormonal birth control or used within last 3 months
Blood pressure on the day of measurements is low or high (SBP <100 or >140 mmHg and/or DBP <60 or >90 mmHg)
Current hypertension or previous hypertensive disorder in pregnancy (gestational hypertension or preeclampsia)
Currently trying to conceive
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N/A
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Study Locations

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Location
State College, PA

Interoception, the 8th Sensory System, Is it measurable?

Sensory processing is often affected in children and adolescents with ASD (autism). The 8th sensory system, coined interoception, is under studied in how it affects children with autism. Our study will compare children with and without autism (ages 11-18 years) using a tool we are developing. Our study hopes to develop psychometric properties of a tool to measure this new sensory sense.
Cheryl Tierney at ctierney@pennstatehealth.psu.edu or 717-531-8414
All
Not specified
This study is also accepting healthy volunteers
Hide eligibility criteria
Inclusion Criteria:
Ages 11-18
Reading at 5th grade level in English
Healthy controls OR high functioning Autism
Exclusion Criteria:
Unable to read at 5th grade reading level
Under age 11 or over age 18
Cannot read English
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N/A
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Prediction of Muscle Force Generation using Ultrasound Imaging and Computational Simulations

The objective of this study is to develop and validate a method to predict force production of individual muscles from ultrasound measurements of muscle stiffness, size, and structure. We hypothesize that there is a linear relationship between muscle size, shear modulus and force generated by the muscle.
Daniel Cortes at researchsubjects@mne.psu.edu or 814-863-3103
All
18 year(s) or older
This study is also accepting healthy volunteers
Hide eligibility criteria
Inclusion Criteria:
Healthy individuals without history of muscle disease or injury
Exclusion Criteria:
Pregnant women
Allergy to ultrasound gels
contraindications to MRI scans
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N/A
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Study Locations

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Location
State College, PA

Patterns of brain function associated with the Affective Processing and Executive Control (APEC) Task

In this pilot study, we wish to test the effectiveness of a novel functional imaging measure that combines affective processing and cognitive control components. The measure (i.e., the Affective Processing and Executive Control (APEC) task) has been designed for use in a large study in children and brings together measures that are developmentally appropriate and have been well established in the literature. However, the combination of measures is unique and so we wish to ensure that patterns of performance and indices of functional activation associated with the paradigm components are as expected. We will do this by examining brain function and behavior during performance of the task while participants undergo functional magnetic resonance imaging. Participants in this pilot study will be healhty adults (N=20, &gt;18 years old, 50% male).
Emma Rose at ejr5384@psu.edu or 8148650114
All
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Aged 18
•65 years
Generally healthy
Right-handed
Exclusion Criteria:
History of drug or alcohol abuse
History of head injury or neurological disease
Current or past psychiatric or neurodevelopmental illness
Claustrophobia
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N/A
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Location
State College, PA

Using Serious Game Technology to Improve Sensitivity to Eye Gaze in Autism

We are developing and testing a computer game to help adolescents with autism improve social skills. In this game, players become a teenage pet detective. They interact with animals and human characters, navigate worlds, find objects, and solve mysteries. The game teaches players to attend to nonverbal social cues and use them to solve pet mysteries. Participants get to play the game from their own home! Adolescents and their families visit the lab prior to the intervention and after the intervention so that we can assess the impact of the game on behavior and social skills.
Dr. Suzy Scherf at suzyscherf@psu.edu or 814-867-2921
All
Younger than 18 years old
This study is also accepting healthy volunteers
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Inclusion Criteria:
Autism Spectrum Diagnosis
Ages 10-18
Speaks in full sentences
Can follow written and oral instructions
Can use a computer in a basic way
•click mouse for responses and use arrow keys on keyboard to navigate
Exclusion Criteria:
Uncorrected vision or hearing problems
Seizures within last 2 years
Does not have minimum of 2nd grade reading level
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NCT02968225
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Location
State College, PA

AWS-PSU: Active Women's Study at Penn State University and AWS-Lincoln: Active Women’s Study Lincoln University

AWS-PSU: Active Women's Study at Penn State University and Lincoln University This research study is being conducted to evaluate the impact of exercise and reproductive function on bone strength. Eligible young women (age 18-30) are those that are generally healthy and either a) exercising and experiencing regular or irregular menstrual cycles, or b) not exercising and experiencing regular menstrual cycles.
Emily Southmayd at eas5377@psu.edu or 814-863-4488
Female
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Regular or irregular menstrual cycles
Age 18-30
BMI between 18 and 30
No hormonal contraception for 6 months
Exclusion Criteria:
Smoking
Currently using medication impacting bone
Current diagnosis of an eating disorder
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N/A
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Location
State College, PA

Evaluation of Concert Hall Acoustics Stimuli

The overall goal of the project is to better understand how people subjectively perceive differences in concert hall acoustics. Subjects will listening to musical passages, side-by-side, in aural simulations of being in different concert halls or rooms. Subjects will then be asked to provide subjective data about the different rooms in which they are listening. The passages may be rated on subjective parameters such as preference, reverberance, warmth, clarity, envelopment, intimacy, brightness, etc. The results from this research will help to better understand how concert-goers perceive different room, and will help acoustic consultants to better design concert hall in the future to produce more pleasing acoustic environments.
Matthew Neal at mtn5048@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
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Inclusion Criteria:
Must have normal hearing thresholds (tested at beginning of test)
Minimum 5 years of combinbed musical training (i.e. private lessons, ensembles, etc.)
Must be actively studying music or involved in a musical ensemble or group.
Exclusion Criteria:
Cannot have sigificant hearing loss (tested at beginning of test)
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N/A
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Location
State College, PA

Quantifying knee injury risk during a wrestling takedown

This study aims to investigate the mechanics of two different wrestling takedown to determine the knee mechanics of the defensive wrestler. Using motion tracking sensors, three-dimensional mechanics will be quantified during 10 wrestling takedowns and the risk of knee injury during each type will be quantified. The results of this study will be used to inform wrestling training programs and knee brace design specifically for wrestlers, who are at a disproportionately high risk for devastating knee injuries.
Zach Fox at zzf5041@psu.edu
Male
18 year(s) or older
This study is also accepting healthy volunteers
Hide eligibility criteria
Inclusion Criteria:
At least 1 year of wrestling experience
Between the ages of 18 and 35
Between 165 lbs and 225 lbs
Exclusion Criteria:
No recent lower extremity injuries
No recent lower extremity surgeries
Females
No wrestling experience
Less than 165 lbs and more than 225 lbs
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N/A
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Study Locations

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Location
Reading, PA