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Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.

247 Study Matches

Improving Autism Screening with Brain-Related miRNA

The central aim of this project is to characterize the expression of exosomal microRNA (miRNA) and nucleic acids in children with autism spectrum disorder (ASD). We propose to measure the expression of extracellular miRNA and nucleic acids in children with ASD. Expression levels of miRNA and nucleic acids from blood and saliva will be compared between children with autism and normally developing controls. The goal of this study will be to identify genetic regulatory mechanisms involved in ASD and provide potential biomarkers for diagnostic screening.
All
Younger than 18 years old
This study is also accepting healthy volunteers
NCT02712853
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Inclusion Criteria:
Age: 1-4 years
Confirmed Diagnosis of Autism or Developmental Delay or Healthy Child
Exclusion Criteria:
Wards of the state
Sensory Impairment (blindness/deafness)
Confounding neurological condition (cerebral palsy, epilepsy)
Gastrostomy Tube Dependence
Active Peridontal Disease
Children's Health, Mental & Behavioral Health
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Hershey, PA

Memory and Aging Study

This research is being done to find out more about changes in the brain as we age and to determine if MRI, genetic (DNA) variations, and neuropsychological tests can be used to evaluate memory loss and cognitive impairment.
Lauren Spreen at lspreen@pennstatehealth.psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Diagnosis of Alzheimer's disease
Diagnosis of Mild Cognitive Impariment
Normal Controls-Cognitively normal functioning
Exclusion Criteria:
Neurological disease (e.g., stroke, tumor, Parkinson's disease, etc.)
Psychiatric disorder (e.g., bi-polar, schizophrenia, etc.)
History of chemotherapy
Presence of a cold or viral infection
Presence of a pacemaker, aneurysm clips, or any metal in body
Neurology
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Location
Hershey, PA

Tongue movement in adults with motor speech disorder

Tongue movement in adults with motor speech disorder
Jimin Lee at jxl91@psu.edu or 814-863-5338
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
be a native speaker of American English
have normal hearing
between 18 and 40 years of age
have no known speech, language, learning or neurological disorders
have very little experience in communicating with people that have motor speech disorders
Exclusion Criteria:
younger than 18 years of age; older than 40 years of age
Not a speaker of American English only
With hearing impairment
have neurologic and/or speech/language disorders
have extensive experience in communicating with people that have motor speech disorders
Neurology, Muscle & Bone, Language & Linguistics
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Location
Hershey, PA
State College, PA

Exploring Parental Influence in Youth Disability Sport Participation

We are conducting an online survey study for parents of children with disabilities that explores their perceptions of participation in disability sport within their communities.
Courtney Jasiulevicius at cmj5308@psu.edu or 813-846-4145
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
has a child with a physical disability or sensory disability
has a child that is enrolled in a disability or adapted sport program
has a child between the ages of 10 and 17
Exclusion Criteria:
does not have a child with a physical or sensory disability
does not have a child with a disability between the ages of 10 and 17
does not have a child that plays a disability or adapted sport
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Penn State Hershey Sitting and Health Study

This study aims to examine the effect of pedaling a compact elliptical device at the desk on employees' work productivity. This study also aims to evaluate the effect of different types of incentives on promoting desk-based pedaling.
Liza Rovniak at activitystudy@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT03274635
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Inclusion Criteria:
Penn State Hershey full time employee
Overweight or obese
Spend at least 5 hours per day sitting at a desk
Have eligible overweight/obese coworker who can do study together with you
18-70 years old
Exclusion Criteria:
Currently pregnant
Planned surgical or medical treatment that will prevent ability to complete study
Heart condition, or chest pain during physical activity
Planned travel or relocation during study period
Already have desk cycling device or treadmill at desk
Heart & Vascular, Prevention, Mental & Behavioral Health
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Hershey, PA

Aging and Language

The purpose of this study is to investigate how language is organized in neurologically normal adults using magnetic resonance imaging (MRI) and behavioral measures. Our overarching goal is to characterize the behavioral and MRI responses associated with language production and language comprehension in older and younger adults, and to examine the relations between age, behavior, cognition, and neural factors.
Michele Diaz at mtd143@psu.edu or 814-863-1726
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Age over 18 years old
Native Monolingual English Speaker
Right-handed
Exclusion Criteria:
History of neurological injury or disease
Taking medications that affect the brain of blood flow
Contraindications to MRI (e.g., pacemaker)
Claustrophobia
Language & Linguistics
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Location
State College, PA

Interoception, the 8th Sensory System, Is it measurable?

Sensory processing is often affected in children and adolescents with ASD (autism). The 8th sensory system, coined interoception, is under studied in how it affects children with autism. Our study will compare children with and without autism (ages 11-18 years) using a tool we are developing. Our study hopes to develop psychometric properties of a tool to measure this new sensory sense.
Cheryl Tierney at ctierney@pennstatehealth.psu.edu or 717-531-8414
All
All
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Ages 11-18
Reading at 5th grade level in English
Healthy controls OR high functioning Autism
Exclusion Criteria:
Unable to read at 5th grade reading level
Under age 11 or over age 18
Cannot read English
Children's Health, Mental & Behavioral Health
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Prediction of Muscle Force Generation using Ultrasound Imaging and Computational Simulations

The objective of this study is to develop and validate a method to predict force production of individual muscles from ultrasound measurements of muscle stiffness, size, and structure. We will place acupuncture needles to the muscles and applied a small amount of current to induce contraction. Force and ultrasound measurements will be performed during muscle contraction. This process will be done in three muscles, one in the arm and two in the leg.
Daniel Cortes at researchsubjects@mne.psu.edu or 814-863-3103
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Healthy individuals without history of muscle disease or injury
Exclusion Criteria:
Pregnant women
Allergy to ultrasound gels
contraindications to MRI scans
Muscle & Bone
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Location
State College, PA

Study driver situation awareness and behavior in connected and autonomous vehicles with a driving simulator

This is a behavioral study that will examine the effect of different message designs and driver characteristics on driver situation awareness and driving behavior in connected and autonomous vehicles. The driving simulator will be used to simulate various traffic events in connected and autonomous vehicle environments. All you need to do is driving on a driving simulator or watch driving scenarios online and complete questionnaires.
Xiaomei Tan at xzt24@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
You must possess a valid and unrestricted driver’s license for at least two years, and display it to the experimenter
You must not be under the influence of alcohol, and have abstained from drinking alcohol for no less than 8 hours prior to participating in this study
You must have normal vision or correct vision.
Exclusion Criteria:
Participants who doesn't possess a valid driver license will be excluded from the study
Participants who drinks alcohol within the 8 hours before the study will be excluded from the study
Education, Mental & Behavioral Health, Language & Linguistics
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Role of microRNA activation of lectin-like oxidized LDL receptor (LOX-1) mechanisms in microvascular dysfunction in women with endometriosis

Endometriosis is a gynecological disorder associated with chronic pelvic pain, pain during intercourse, and infertility. With endometriosis, endometrium-like tissue is found in sites outside the uterine cavity. This disorder affects 6% - 10% of women of reproductive age. It can be as high as 35-50% in women who have pain or infertility. Endometriosis is associated with higher risk of hypercholesterolemia and hypertension that increases risk for cardiovascular disease (CVD). CVD is characterized by dysfunction of the blood vessels of the body. CVD is the leading cause of death in women. Two groups of women complete this study: 1) healthy women between the ages of 18 and 45 years (Controls); 2) women between the ages of 18 and 45 years with endometriosis. The screening and two experiments include blood draws. After passing a medical screening, each subject participates in a microdialysis (MD) experiment before and after 6-9 days of oral atorvastatin therapy (10mg/day). Atorvastatin (brand name: Lipitor) is an FDA-approved drug that physicians prescribe to lower blood cholesterol. The atorvastatin also suppresses substances made by the body that increase the risk of CVD. MD is a procedure in which a thin tube of membrane that mimics a capillary blood vessel is implanted in the skin. Substances of interest are added to the saline flowing through the MD sites and are delivered into small areas of skin. The MD experiments combine the perfusion of the test-substances with local heating of the skin to explore the causes for the dysfunction of blood vessels and increased risk for CVD that occurs with endometriosis.
Susan Slimak at sks31@psu.edu or 814-863-8556
Female
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Women, Ages 18-45
Do or do not have endometriosis
Have normal blood pressure
Exclusion Criteria:
Use of nicotine-containing products (e.g. smoking, chewing tobacco, etc.)
High Blood Pressure
Abnormal liver function
Known allergy statins (Lipitor)
Pregnant or Breastfeeding
Heart & Vascular, Pregnancy & Infertility, Women's Health
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Study Locations

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Location
State College, PA

Invisible Sojourners: Second Language Socialization Among International Spouses

This study will examine how international spouses improve their English ability and form connections with the local community. Participants will be interviewed to learn about their experiences. Social events that are found to be positive will be recorded so that the interactions in that space can be analyzed to determine how they help international spouses.
Jade Sandbulte at jfs5644@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Traveled to the U.S. with a spouse who was enrolled at Penn State
Understands spoken English
Exclusion Criteria:
Is not a student at Penn State OR was not a student when you first arrived
Education, Language & Linguistics
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Location
State College, PA

Investigation of Semantic Processing in Context

The purpose of this study is to investigate the effects of context on the processing of words in young adults with and without an autism spectrum disorder. The knowledge gained may lead to further understanding of the cognitive and linguistic processing of individuals with autism spectrum disorder—how they understand and see the world around them. The study is being conducted at our on-campus lab and includes the completion of some standardized paper and pencil tests and some computer-based activities. Participants receive compensation for their participation.
DIANE WILLIAMS at dlw81@psu.edu or 814-865-3177
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Speak English as primary language
Normal or corrected to normal vision
Normal hearing
With or without a diagnosis of an autism spectrum disorder or Asperger syndrome
Exclusion Criteria:
Cannot speak sentence length English
Vision problems (uncorrected)
Hearing problems
Mental & Behavioral Health, Language & Linguistics
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State College, PA

Reducing Perception Error in Diagnostic Radiology

This research is being done to find out the relationship between an individual’s mental state and how well they perform visual-perceptual tasks. This will allow us to understand the brain processes related to errors in image perception, to understand how mental states impact medical image interpretation. Overall, this research will help us develop training programs to reduce the amount of perceptual errors in diagnosing images
Lauren Spreen at lspreen@pennstatehealth.psu.edu or 717-531-5857
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Radiologists with different levels of experience
Healthy adults, with college or advanced degree
Normal or corrected to normal vision
Exclusion Criteria:
Non-English speaking
Pregnant or lactating
Presence of pacemaker, aneurysm clips, or any metal in the body
A history of welding or grinding
Claustraphobia
Education
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Study Locations

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Location
Hershey, PA

Asymmetric neurodegeneration of central olfactory system in early-stage Parkinson’s disease

This research is being done to study the deterioration of the central olfactory system (sense of smell system) in the brains of patients diagnosed with H&Y stage 1 or 2 Parkinson’s disease compared to that of healthy volunteers.
Lauren Spreen at lspreen@pennstatehealth.psu.edu or 717-531-5857
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Cognitively-normal H&Y stage 1 PD patients. A physician-documented parkinsonian symptom onset between the ages of 40-59. 1st visit prior to age 65. PD stage I diagnosis must be documented for a min of 2 years.
Cognitively-normal H&Y stage 2 PD patients. H&Y stage 2, as defined by an exam in the practically defined “off” state, and have a diagnosis of PD at the age of 59 or younger. 1st visit prior to age 65
Healthy participants between ages 40-64 at their first visit.
Able and willing to provide informed consent
Fluent in written and spoken English
Exclusion Criteria:
Parkinson-plus syndrome
Dementia
Previous antipsychotic or anti-dopamine drug therapy
Traumatic head injury
Other neurological diseases or disorders
Neurology
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Study Locations

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Location
Hershey, PA

Site For COMET-PCOS

Site For COMET-PCOS
Patsy Rawa at prawa@pennstatehealth.psu.edu or 717-531-3692
Female
18 year(s) or older
This study is also accepting healthy volunteers
NCT03229057
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Inclusion Criteria:
Polycystic ovary syndrome (PCOS)
BMI >=25 to <=45
In good general health
Willing to avoid pregnancy for duration of study
Exclusion Criteria:
Currently pregnant or desire of pregnancy
Currently breastfeeding
Untreated thyroid disease
Untreated hyperprolactinemia
Type 1 or Type 2 diabetes
Women's Health
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Study Locations

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Location
Hershey, PA

Immersive Virtual Reality Storm Surge: Scale and Risk Perception

Evaluating if an immersive virtual reality experience of storm surge flooding gives people an understanding of the scale of the flooding and increases their risk perception of such flooding compared to a non-immersive desktop experience.
Mark Simpson at marksimpson@psu.edu or 575-491-5512
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Normal or corrected-to-normal vision
English-speaking
Exclusion Criteria:
Under age 18
Education
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State College, PA

Creative Thinking and Problem Solving

This is a behavioral study that will examine cognitive processes relevant for creative thinking. Participants will be asked to complete a series of cognitive tasks and self-report measures on a computer.
James Lloyd-Cox at jll487@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
18 years or older
They must consent to participate in research
Healthy volunteers

Native English Speakers
Exclusion Criteria:
Cannot be non-native English speakers
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State College, PA

A more naturalistic interaction: using back-channeling in smart-speakers to indicate active listening

In this project, we aim to extend the capabilities of smart-speakers (such as Amazon Alexa, Google Home, Siri, etc.) to support more engaging interactions with their users. Specifically, we would like to make the future of smart-speakers more conversational. One of the key aspects in developing a conversation is to be an active listener; showing interest in the speaker and allowing them to extend their turn in talk. In this study we investigate how smart-speakers can become better listeners by incorporating some of the human-human conversational features of active listening. Our question is, how can smart-speakers extend the users' turn in talk by being better listeners?
Nasim Motalebi at nfm5140@psu.edu or 814-753-2081
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
18 years of age and older
English speaking individuals
Exclusion Criteria:
under 18 years old
non english-speaking individuals
Mental & Behavioral Health
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Study Locations

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Location
State College, PA

Coparenting, Infant Sleep, and Infant Development: An Intervention Study

This application proposes a randomized clinical trial (RCT) to evaluate the effects of a sleep-enhanced adaptation of an evidence-based transition-to-parenting coparenting intervention program [Family Foundations - FF). The study has three arms. In one arm, families will experience FF as originally formulated; in the second, families will receive an adapted FF that emphasizes coparenting in infant sleep contexts; the third arm will serve as controls. Assessments of coparenting and parenting in infant sleep contexts, parental adjustment to infant sleep behavior, choices about sleep arrangements, infant and parent sleep quality, and infant socio-emotional functioning, will serve as outcomes.
Morgan Loeffler at FF@psu.edu or 717-695-7050
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT03187561
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Inclusion Criteria:
Parents must live together
Parents must be expecting their first baby together
We must start working with the couple before the baby is born
Parents must be 18 years or older
Families who can speak and understand English
Exclusion Criteria:
Single-parent families
Families with more than one-child
Familes who cannot speak or understand English
Families in which one parent is under the age of 18
Pregnancy & Infertility, Sleep Management, Women's Health
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Carlisle, PA
Harrisburg, PA
Hershey, PA

Walking through the forests of the future: Using data-driven iVR to visualize forests under climate change

We used a combination of ecological modeling, procedural modeling, and virtual reality to provide an embodied experience of “walking through the forests of the future”. This study will provide empirical evidence of the effectiveness of this immersive experience based on users’ feedbacks on different kinds of tools we developed.
Jiawei Huang at jzh87@psu.edu or 734-355-5327
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
forestry or climate science related majors (include but not limited to agricultural sciences, environmental resources management, forest ecosystem management, plant science, ecology, biology, meteorology and atmospheric science)
undergraduate or graduate students at Penn State University who are older than 18.
participants should be healthy (without contagious disease)
Exclusion Criteria:
people under 18
people who are cognitively impaired
people who have contagious disease
Education, Language & Linguistics
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Location
State College, PA

"Alexa, I’m in pain! "A Real-Time Mindfulness Intervention to Control Pain: Delivery Through a Conversational Agent

We are interested in learning about people’s experiences with using the Amazon Alexa for delivery of a real-time mindfulness intervention to help with chronic pain management. Participation will include a free day-long introductory mindfulness training followed by daily use of mindfulness practices using the Amazon Alexa to establish a habit of use. The participants will use our developed Amazon Alexa app ("skill") and provide assessments. We will ask participants to complete short daily surveys and a follow-up interview.
Sebrina Doyle at sld40@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Individuals who had some experience with chronic pain over the last 6 months
Living in homes with internet access
Willing to use a smart-home device (Amazon Alexa)
Have access to a smart phone
Read, write, and speak English
Exclusion Criteria:
Under 18 years old
Major mental health issue that is not currently under advisement of a doctor/therapist
Actively struggling with addiction to substances or newly in recovery
Participants who currently report using mindfulness practices more than 1x a month
Pain Management
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State College, PA

Describing your voice: Viewpoints from pre-professional voice users

The purpose of this study is to conduct semi-structured interviews with students at Penn State who are working towards degrees in fields that require a high vocal demand (e.g. teachers, lawyers, singers, actors, etc). The purpose is to learn more about what students think about their voice, what they know about protecting their voice, and what they would do if they had a voice disorder. This information can be used to design interventions and preventative outreach programs for these students.
Nicole Etter at oppal@psu.edu or 814-863-2021
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
18 years and older
Working towards a degree in a field requiring high vocal demand (e.g. future teachers, lawyers, voice performers including singers and actors)
Exclusion Criteria:
Currently being treated for a voice disorder
Prevention, Education, Language & Linguistics
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Randomized trial of low nicotine cigarettes plus electronic cigarettes in smokers

This study will examine the health effects of lowering the nicotine content in cigarettes while having access to an electronic cigarette.
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT04058717
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Inclusion Criteria:
Ages 21-70
Smoke 5 or more cigarettes per day
Must be willing to both switch to a different type of cigarette and try an electronic cigarette
No serious quit attempt or use of smoking cessation medication in the past 30 days
Meet diagnostic criteria for current or lifetime mental health condition
Exclusion Criteria:
Women who are pregnant, nursing, or trying to become pregnant
Any known allergy to propylene glycol or vegetable glycerin
History of difficulty providing blood samples
Other member of the household currently participating in the study
Unstable or significant medical condition in the past 3 months
Smoking, Vaping, Nicotine and Tobacco, Addiction & Substance Abuse, Mental & Behavioral Health
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Location
Hershey, PA

Assessing cognitive and psychosocial mechanisms of Useful Field of View cognitive training using ecological momentary assessment

We are interested in how brain games impact everyday life in healthy older adults. Participants will play 20 hours of brain games on a study-provided laptop, and we will examine how the brain games impact everyday life. This study will be performed remotely in participants homes using study-provided laptops. Some participants may also participate in 2 optional visits with brain MRI scans at Penn State University and at home sleep monitoring.
Courtney Fine at cjf5860@psu.edu or 814-865-4773
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT04651582
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Inclusion Criteria:
65 or older
no diagnosis of dementia
available for 6 months
Exclusion Criteria:
64 or younger
dementia or motor movement disorder diagnosis
cognitive training within past 2 years
Mental & Behavioral Health
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Cardio-metabolic effects of diets including pecans

The purpose of the study is to examine how the inclusion of 2 oz./day of pecans into a typical American diet and a healthy diet affect risk factors for heart disease and diabetes.
Philip Sapp at pzs5199@psu.edu or 866-778-3438
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT04487808
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Inclusion Criteria:
Age 25-70 years
BMI 25-40 kg/m2
Not taking anti-hypertensive, lipid lowering, glucose lowering drugs, steroids, or antibiotics
Not currently using tobacco products or smoking
Exclusion Criteria:
Established heart disease, stroke, diabetes, liver, kidney, autoimmune diseases or inflammatory conditions such as gastrointestinal disorders or rheumatoid arthritis
Tree nut allergy
Pregnant, lactating, planning to become pregnant or have given birth in the past year
Weight loss of ≥10% of body weight within the past 6 months
Not willing to consume all meals and snacks provided for the study
Food & Nutrition
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Location
State College, PA

Understanding the effect of drivers’ profile information on riders’ feedback in ride-sharing context

This study aims to understand ways to affect how riders perceive and provide feedback to drivers through technology intervention. Particularly, we investigate how presenting drivers’ personal profile under different trip conditions may lead to differences in the ways riders may provide feedback. We hypothesize that riders will provide positive feedback when provided drivers’ personal information when the trip goes well, and that riders will provide less negative feedback when provided drivers’ personal information when the trip goes bad due to uncontrollable reasons.
Ning Ma at nzm37@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Taken at least 10 Uber/Lyft ride in the last 12 months.
You are willing to share several of your past Uber/Lyft trip records in the app with us.
Exclusion Criteria:
You are a current or past employee with one of the ride-sharing corporations (Uber/Lyft)
Education
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Location
State College, PA

The Daily Reflections Study

This 14-day daily diary study is being conducted to better understand how young adults' thoughts and feelings about their bodies influence their health behaviors, and how their daily experiences and characteristics contribute to their health behaviors. Participants will be asked to complete a 10-20 minute baseline survey and a brief (5-8 minutes) daily survey each day for 14 consecutive days. Surveys will include questions about participants' mental and physical health, emotions, relationships, health behaviors, thoughts, and experiences.
Anna Hochgraf at akh7@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Age 18-25 years
Enrolled in undergraduate degree program at Penn State's University Park Campus
Access to internet between 8:00 AM and 2:00 PM
Proficient in English language
Living in University Park or State College this semester
Exclusion Criteria:
Not between ages 18-25 years
Not enrolled in undergraduate degree program at Penn State's University Park campus
No access to internet between 8:00 AM and 2:00 PM
Not proficient in English language
Not living in University Park or State College this semester
Smoking, Vaping, Nicotine and Tobacco, Mental & Behavioral Health, Women's Health
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Neural Correlates of Cognitive Dysfunction in Postural Tachycardia Syndrome

Postural tachycardia syndrome (POTS) is a chronic syndrome in which the heart beats too quickly when standing. POTS primarily affects young women. People with POTS also experience symptoms such as feeling faint, fatigue, nausea, and mental clouding or "brain fog." “Brain fog” is one of the most bothersome symptoms of POTS and it is unknown why people with POTS experience this symptom. Some studies have shown that POTS patients have problems with attention, memory and executive function (ability to plan, organize information, and adapt to changes) while seated and when upright. In this study, we will evaluate how brain function during mental tasks is affected in people with POTS compared to healthy volunteers. All volunteers will complete mental tasks while lying down and standing. If eligible, we will measure brain activity using functional magnetic resonance imaging (fMRI).The findings from this study will increase our understanding of the mental complaints in people with POTS, to hopefully help with development of new treatments.
Amanda Miller at aross1@pennstatehealth.psu.edu or 717-531-7676
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT04137757
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Inclusion Criteria:
Men and women of all races
18- 60 years old
Previously Diagnosed with POTS or healthy people without chronic illness
Capable of giving informed consent
Exclusion Criteria:
Age <18 years or >60 years
Pregnant or breastfeeding women
Other potential causes for tachycardia (e.g. prolonged bed rest, dehydration)
Taking stimulant medications within the past 3 months as these may alter cognition
Unable to tolerate an MRI scanner (e.g. claustrophobia, implanted metal)
Heart & Vascular, Neurology
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Location
Hershey, PA

Collaborative Research: Measuring and Enhancing Scientific Creative Thinking for STEM Education and Research: Classroom-Aligned Assessment and Network Neuroscience-Based Mechanisms

The project is interested in understanding how the brain supports creative thinking in the context of solving scientific problems. During functional magnetic resonance imaging (fMRI) and behavioral experiments, participants will be presented with open-ended scientific questions and asked to produce responses.
Brendan Baker at brendan.baker@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Over 18 in age
English is first language
Right-handed
No history of neurological injury or disease
Under 300 lbs in weight
Exclusion Criteria:
Claustrophobic
Taking medication that affects brain or blood flow
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Study Locations

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Location
State College, PA

Characterization and Exploration of Cognitive Assistants in the Space of Knowledge and Social Demands

The objective of this study is to investigate the effects of artificial intelligence on ideation in groups (specifically the process of brainstorming). Facilitation and facilitator/participant perceptions will also be analyzed. This study collects qualitative data through surveys, interviews, and audio/video recording.
Torsten Maier at torstennamaier@psu.edu or 812-781-0014
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Individuals must be 18 years of age or older
Individuals must be an undergraduate OR graduate student at Penn State
Exclusion Criteria:
Individuals under the age of 18
Individuals who are not an undergraduate OR graduate student at Penn State
Education, Language & Linguistics
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Study Locations

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Location
State College, PA