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410 Study Matches

Social Values for Bird Conservation in PA

The purpose of this study is to examine public attitudes and willingness to pay for bird conversation activities on private forest lands.
Melissa Kreye at mxk1244@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
lives in Pennsylvania
Exclusion Criteria:
Does not live in Pennsylvania
Education
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Learning about Girls’ Emotions Study

In this study, we hope to better understand whether certain behaviors, reactions and feelings associated with Borderline Personality Disorder (BPD) are found in girls, and how these things may or may not be related to ADHD and brain activity patterns. BPD is a condition that usually is found in adults, and is linked to emotional and behavior problems in children. In doing so, we are asking girls between the ages of 8-12 years and their parents to participate in our research.
Attention and Behavior Clinic Research Group at abc@pennstatehealth.psu.edu or 717-531-0003, ext=285966
Female
Younger than 18 years old
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Ages 8-12 years
Female
With or without ADHD Diagnosis
Speak fluent English
Exclusion Criteria:
Younger than 8 years old
Older than 12 years old
Male
Neurology, Mental & Behavioral Health
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Study Locations

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Location
Hershey, PA

Sharing healthy activities among family members: A lightweight photo journaling design experiment

We want to develop and deploy alternative design solutions to examine how non-collocated families exchange support and collaborate on healthy living via online platform in their everyday life.
Jomara Sandbulte at jmb89@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Individuals should be 18 years or older, working adults, financially self-reliant
Individuals should have living family members who would be willing to take part on the study
Individuals should have a computer or tablet with internet access
Individuals should have Facebook account
Individuals should be living geographically distant from family members
Exclusion Criteria:
Non-English speakers
Elderly people cognitively impaired
Minors (age under 18)
Adult children who are not financially independent of their parents
Food & Nutrition, Education, Mental & Behavioral Health
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Study Locations

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Location
State College, PA

Collaboration and moderation in online games

The project seeks to use empirical methods such as interview and survey to understand how game players collaborate in video games (e.g., how they work together to kill a monster in game), when breakdowns happen in collaboration (e.g., they blame each other when they fail to achieve their in-game goal), and what moderation mechanisms could be used to enhance collaboration (e.g., mechanisms that discourage them from harassing their teammates).
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
The proposed study will involve adults no less than 18 years old who have played online games.
Participants need to speak English.
Exclusion Criteria:
Vulnerable populations such as pregnant women, children, cognitive impaired adults, and prisoners.
People who have never played online games.
People who are less than 18 years old.
People who do not speak English.
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Barriers to Transgender Healthcare in Rural Communities

The purpose of this study is to comprehensively explore the barriers to healthcare among rural transgender or non-binary adults in rural Pennsylvania, using a convergent mixed-methods approach.
Oluwamuyiwa Adebayo at owa2@psu.edu or 814-867-4656
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Aged 18 years and older
Identify as transgender or non-binary or genderqueer
Fluent in English
Reside in Rural Pennsylvania County
Exclusion Criteria:
Younger than 18 years
Identify as cisgender
Men's Health, Prevention, Women's Health
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Speech Production in Noise

This study aims to investigate the effect of background noise on speech production. Participants will be asked to describe an image or concept while their speech is recorded.
Catherine Pham at catherine.pham@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
18 years of age or old
Native monolingual English speaker
Minimum high school education
Normal or corrected-to-normal vision/hearing
Exclusion Criteria:
Those unable to consent, pregnant women, children, and prisoners will be excluded
Under 18 years of age
Non-native monolingual English speaker
Less than high school education
Non-normal vision/hearing
Language & Linguistics
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Study Locations

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Location
State College, PA

EAT-10 Implementation in Amyotrophic Lateral Sclerosis (ALS) Clinic

This study will evaluate the implementation of a clinical tool (EAT-10) within the Penn State Hershey ALS Center. Participation in the study requires completion of 2 surveys - one during an ALS clinic visit and another one 6 weeks later. This will be repeated at up to 10 visits.
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
At least 18 years old
Diagnosed with motor neuron disease, including but not limited to amyotrophic lateral sclerosis (ALS), primary lateral sclerosis (PLS), or progressive muscular atrophy (PMA)
Receive care at the Penn State Hershey ALS Center
Exclusion Criteria:
Significant cognitive impairment
Neurology
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Examining views associated with physical exercise and its connection to diet, social connectivity, and stress reduction: Focus Groups

The primary objective of this study is to examine, via focus groups, the perceptions that are held by potentially-eligible subjects in the PSH DPP program in regard to the importance of physical exercise, particularly within the context of diet, social connectivity, and stress reduction. These perspectives will then be used to help develop, test, and refine additional motivational text messages that can be used in a text messaging intervention.
Selena Ortiz at suo13@psu.edu or 814-863-8041
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Be at least 18 years old and under age 65
Body Mass Index ≥25 kg/m2 (≥23 kg/m2 if Asian)
Have no previous diagnosis of type 1 or type 2 diabetes
Fluent in English
Exclusion Criteria:
Under 18 years old and over age 65
Body Mass Index <25 kg/m2 (<23 kg/m2if Asian)
Previous diagnosis of type 1 or type 2 diabetes
Not fluent in English
Prevention, Education, Diabetes & Hormones
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Study Locations

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Location
State College, PA

Understanding the Experiences of College Students of Color with Psychiatric Disabilities

The purpose of this study is to develop a better understanding of the lived experiences of college students of color with psychiatric disabilities, particularly related to the formation of racial identity, disability identity, and the impact of perceived discrimination.
Amber O'Shea at amo5208@psu.edu or 814-867-5721
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Currently enrolled as a college student
18 years of age or older
Capable of providing informed consent
Diagnosis of a psychiatric disability
Identify as a person of color
Exclusion Criteria:
Adults unable to provide legal consent
Individuals who are not yet legal adults
Prisoners
Unable to speak/read English Language at time of interview
Addiction & Substance Abuse, Education, Mental & Behavioral Health
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Study Locations

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Location
State College, PA

Identification of Critical Thermal Environments for Aged Adults

The earth’s climate is warming, and the number of heat waves has increased in recent years. At the same time, the number of adults over the age of 65 is growing. Humans sweat and increase blood flow to the skin to cool their body when they get hot. Older adults do not do this as well as young adults. This makes it harder to safely exercise in warm and/or humid conditions. It is important to learn about safe limits of heat and humidity for older adults to exercise. Also, nearly 40% of adults over age 50 take aspirin to lower their risk for heart disease. Our lab has shown that aspirin lowers the control of body heat. In this study, we will determine critical temperature and humidity environments above which normal body temperature cannot be maintained in young and older adults. We will also look at how aspirin may change critical temperature and humidity thresholds in older adults.
Susan Slimak at sks31@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Healthy subjects 18-30 or 65-85 years of age
Non-obese
Normal blood glucose (HbA1C <5.7%)
Normal cholesterol (LDL cholesterol <180 mg/dl)
Asymptomatic and no signs/symptoms of disease
Exclusion Criteria:
Have any conditions to advise against low-intensity physical activity
Received a prior diagnosis of cancer, cardiovascular disease, diabetes, or metabolic syndrome
Medications that could alter cardiovascular responses or body temperature regulation during exercise (blood pressure reducers, fever reducers, anti-depressants, etc.)
Tobacco or recreational drug use
Post-menopausal women taking hormone replacement therapy
Heart & Vascular, Sports Medicine
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Study Locations

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Location
State College, PA

Developing a Recommendation System for Local Community Events

In this study, we investigate a recommender system for public, local events in Centre County, PA. Currently, there is no platform that aggregates all the events that take place in a community. The data is fragmented among many platforms and it can be difficult for people to find interesting things to do. Participants will interact with our software system and discuss their experiences through a survey and/or interview.
Tiffany Knearem at tak54@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Must be 18 years or older
Must be a University Park student or local resident of Centre County
Exclusion Criteria:
Persons under 18 years of age
Persons who do not live in Centre County, PA
Education
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Study Locations

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Location
State College, PA

An open-label, multinational study of fitusiran prophylaxis in male pediatric subjects aged 1 to less than 12 years with hemophilia A or B.

A study to confirm the appropriate dose of fitusiran when given to severe Hemophilia A or B patients with inhibitors between the ages of 1 and &lt;12 years old.
Male
Younger than 18 years old
This study is NOT accepting healthy volunteers
NCT03974113
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Inclusion Criteria:
Severe hemophilia A or B (FVIII <1% or FIX ≤2%)
Inhibitory antibodies to FVIII or FIX
Age 1 to <12 years
Exclusion Criteria:
AT activity <60% at screening
Co-existing thrombophilic disorder
Central or peripheral indwelling catheter, with a hx of venous access complications
Anticipated need of surgery during the study
Presence of clinically significant liver disease
Blood Disorders
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Study Locations

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Location
Hershey, PA

Gait Variability Due to Ankle Stiffness Imposed by an Exoskeleton

Using an exoskeleton to investigate the effects of changing ankle stiffness on parameters that predict fall risk. Subjects walk on a treadmill wearing an exoskeleton controlled to act with a certain stiffness.
Dave Schmitthenner at dhs5071@psu.edu or 585-313-1131
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
BMI under 30.
Normal Ankle function.
Calf width less than 5 inches, sitting knee height greater than 16 inches, shoe size less than men's 10 and women's 12.
Able to walk for 10 minutes at a time without assistance.
Able to walk for at least 45 minutes total within 2.5 hours.
Exclusion Criteria:
Previous or existing neurological pathologies, injuries or illnesses likely to affect gait.
History of neuromuscular disorders or lower limb joint replacements.
Currently taking blood thinners (small risk of bruising).
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Study Locations

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Location
State College, PA

User experience with smart devices

This study investigates users’ experience with smart devices. This study makes further implications for designing more user-friendly devices for better user experience. We aim to make such contributions by answering these questions: 1. How do users interact with smart devices? 2. What challenges do users face when using smart devices? 3. What strategies do users apply to adapt themselves to smart devices? 4. What service do smart device producers provide for users to get a better user experience? 5. When does user experience break down when interacting with smart devices? The study methods are social media data analysis, interview, survey, and focus group.
Yao Lyu at yml5549@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
18 years or elder
all genders included
have prior experience with smart devices
Exclusion Criteria:
younger than 18 years old
all vulnerable populations, such as pregnant women, cognitive impaired adults, and prisoners.
no prior experience with smart device
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Study Locations

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Location
State College, PA

Effect of oral black raspberry administration on oral cell DNA adducts in smokers

This is an intervention study that will examine the effect of black raspberry lozenges on mouth cell DNA damage in smokers.
Nicolle Krebs at nkrebs@pennstatehealth.psu.edu or 717-531-5673
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Smokers (cigarettes per day or more)
No plans to quit smoking in next 4 months
Healthy
Willingness and ability to attend 4 visits over 14 weeks
21-65 years of age
Exclusion Criteria:
Unstable or significant medical condition
Women who are pregnant or nursing
Use of marijuana or other illegal drugs
Any known allergy to raspberries
Heavy drinking (>4 drinks/day, 5 days/wk)
Prevention
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Study Locations

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Location
Hershey, PA

Novel Therapies to Improve Cardiac and Skeletal Muscle O2 Supply-Demand Mismatch in Older Adults with Peripheral Arterial Disease: Esmolol infusion

This research is being conducted to determine how oxygen delivery to the heart and leg muscles is altered when beta-1 receptors (receptors involved in the “fight or flight” response) are temporarily blocked through a medication infused into an arm vein (compared to when a simple saline solution is infused). This will help us determine whether the medication, Esmolol, a beta-1 blocker, can eventually be used in the evaluation or treatment of PAD.
Aimee Cauffman at acauffman@pennstatehealth.psu.edu or 717-531-1617
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT04181606
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Inclusion Criteria:
Men and women age 21-85 years
Healthy
Not currently taking medications affecting heart rate or contractility
Exclusion Criteria:
Females who are pregnant or lactating
Bleeding or clotting disorder
HIstory of angina or recent heart attack
Diabetes or hypertension
Heart & Vascular
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Study Locations

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Location
Hershey, PA

The effectiveness of a community-based steps challenge on cardiovascular health outcomes in previously sedentary adults

The purpose of this study is to determine the effect of Blair County’s Active Living Steps Challenge on cardiovascular health in physically inactive adults participating in the intervention compared to a control group of adults also living in Blair county who are not participating in the Steps Challenge.
Nicole Gilbertson at nmg46@psu.edu or 814-949-5016
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Males and Females
Ages 18-65 years old
Currently living and/or working in Blair County, Pennsylvania
Not currently participating in planned, structured physical activity at least 30 minutes at moderate intensity on at least 3 days/week for at least 3 months
Ability to walk for >10 minutes at a time
Exclusion Criteria:
Known cardiovascular disease, chronic obstructive pulmonary disease, cancer, diabetes, or renal disease
Conditions associated with cognitive impairment or medical instability that puts the subject at risk
Signs or symptoms suggestive of cardiovascular, metabolic, or renal disease
Females currently pregnant or breastfeeding
Currently involved in a program to gain or lose weight
Heart & Vascular, Prevention
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Study Locations

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Location
Altoona, PA

Site for Phase III IGRT and SBRT VS IGRT and Hypofractionated IMRT for Localized Intermediate Risk Prostate Cancer (NRG-GU005) (PSCI# 19-073)

The purpose of this study is to compare any good and bad effects of using stereotactic body radiation therapy (SBRT), a technique that gives treatment in a shorter amount of time compared to the usual radiation therapy. SBRT is experimental for treating this type of cancer. SBRT uses special equipment to position a participant and precisely deliver radiation to tumors in the body. Both the study and the usual radiation treatments use daily images to guide the radiation treatment to protect normal tissue. The study treatment, treatment over a shorter amount of time, may prevent the tumor from returning but it could also cause side effects. This study will allow the researchers to know whether this different approach using SBRT is better, the same, or worse than the usual approach. To be better, the study treatment should increase the time without the cancer coming back by six months or more compared to the usual approach, and show improvements in side effects to the bladder or rectum.
Male
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03367702
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Inclusion Criteria:
ECOG Performance Status 0-1 60 days prior to registration
Previously untreated localized adenocarcinoma of the prostate
Clinical stage by digital rectal exam of either T1c or T2a/b
The prostate volume must be < 60 cc as reported at time of biopsy or by separate measure with ultrasound or other imagining modalities including MRI or CT scan
Age is 18 years or older
Exclusion Criteria:
Definitive clinical or radiologic evidence of metastatic disease. No nodal involvement or evidence of metastatic disease allowed as defined by screening of the pelvis
Definitive T3 disease on MRI
Prior or current invasive malignancy with current evidence of active disease within the past 3 years
Prior systemic chemotherapy for the study cancer; note that prior chemotherapy for a different cancer is allowable; must be off treatment
Prior radiotherapy to the region of the study cancer that would result in overlap of radiation therapy fields
Cancer
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Study Locations

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Location
Hershey, PA

NRG-GU002: Phase II-III Trial Of Adjuvant Radiotherapy and Androgen Deprivation Following Radical Prostatectomy With or without Adjuvant Docetaxel

Purpose of this study is to compare any good and bad effects of using docetaxel along with the radiation therapy and hormone suppression therapy versus using radiation and hormone suppression therapy alone in men with a high chance of prostate cancer recurrence after surgically removing the prostate.
Daniel Ward at dward1@pennstatehealth.psu.edu or 610-378-2336
Male
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03070886
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Inclusion Criteria:
post-prostatectomy with baseline Gleason ≥ 7
post prostatectomy PSA never undetectable
Any type of radical prostatectomy is permitted
Prior androgren deprivation therapy allowed
Exclusion Criteria:
Clinical or radiologic evidence of metastatic disease
Prior radiotherapy to the prostate
Prior chemotherapy for prostate cancer
Prostatectomy performed greater than 365 days prior to study entry
Cancer
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Study Locations

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Location
Reading, PA

A Survey to Estimate the Socio-Economic Impact of the Novel Corona Virus (COVID-19) Pandemic

We are experiencing global outbreak of coronavirus (COVID-19) recently. Millions of people are suffering and dying every day, in spite of putting our best efforts. We are doing this survey to understand people’s reaction to this situation. The survey will ask about your knowledge, practices and worries. Your response will help us to understand how to better control these situations. Your feedback is highly important to us, as we need to find out the best way to stop the disease from spreading and killing thousands of lives, and to reduce the stress among the population.
Pritish Mondal at pmondal@pennstatehealth.psu.edu or 717-897-0652
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
General population
Adult
Exclusion Criteria:
Age below 18 years
Mentally impaired
Infectious Diseases & Immune System, Prevention, Lung Disease & Asthma
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