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442 Study Matches

The Role of Emojis in Generating and Responding to Critiques of Work

An online survey about emojis for text feedback on a short story or design. You categorize emojis for this task, write a critique with emojis, and then answer a survey for an Amazon gift card.
Chulakorn Aritajati at cya5092@psu.edu
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
18 year old or older
Can read and write English
Exclusion Criteria:
Under 18 years
Education, Language & Linguistics
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Behind virtual world building: Studying virtual reality environmental characteristics

This is a user study to investigate the environmental characteristics of virtual reality (VR). This study will provide empirical evidence of the essential characteristics based on users’ feedbacks. During your visit, you will receive a brief training about using a VR headset and navigating in the virtual environment. After the training, you will explore the virtual environment, complete tasks in VR, and answer questions regarding your feelings to our VR application.
Jiawei Huang at jzh87@psu.edu or 734-355-5327
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
students at Penn State
healthy participants
Exclusion Criteria:
students that are cognitive impaired
students under 18
students with contagious disease
Education, Language & Linguistics
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Study Locations

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Location
State College, PA

Verbal Encoding and Visuospatial Recall in Autism Spectrum Disorder

In this study, we ask adults with autism spectrum disorder to view short animated clips and then provide verbal narratives and visuospatial reenactments of the animations. Our goal is to better understand the ways verbal and visuospatial working memory each contribute to memory formation and expression in autism.
Diane Williams at dlw81@psu.edu or 814-865-3177
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
age range 18 to 50 years
sentence-length English as primary language
normal or corrected to normal vision
have an autism spectrum disorder
willing to consent and complete study requirements
Exclusion Criteria:
cannot communicate in sentence-length English
uncorrected vision problems
significant learning problems
unwilling to consent or complete study requirements
Mental & Behavioral Health, Language & Linguistics
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Study Locations

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Location
State College, PA

Heritage Speakers Processing of the Spanish subjunctive during online comprehension

This study investigates how individuals who speak Spanish as a first or second language understand the subjunctive as they listen to contextualized sentences and their eye movements are recorded.
Priscila Lopez-Beltran at pul57@psu.edu or 814-206-6437
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
First language is English, second language is Spanish.
Started learning Spanish after age 6.
Very high proficiency in Spanish (at least level 400).
Born and raised in the U.S.
No history of neurological disorders or language disorders.
Exclusion Criteria:
Only speaks English.
Started learning English and Spanish at the same time.
Was born in a Spanish-speaking country.
Low or intermediate proficiency in Spanish.
History of neurological disorders or language disorders.
Language & Linguistics
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Study Locations

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Location
State College, PA

Functional magnetic resonance imaging (fMRI) and psychophysical studies of sensory perception and cognition

The purpose of this study is (1) to understand how the brain processes sensory information and (2) how this is affected by factors like blindness or synesthesia. In addition to behavioral testing, the study will use functional magnetic resonance imaging (fMRI) which enables us to take pictures of the brain while you are doing a task, using an instrument called an MRI scanner.
Simon Lacey at slacey2@pennstatehealth.psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Healthy adults over 18 years old
Normal or corrected-to-normal vision
No other sensory deficits
Adults who experience synesthesia
Must pass MRI safety screen (if applicable)
Exclusion Criteria:
Pregnant women (excluded from fMRI studies)
Minors under the age of 18
Individuals who fail the MRI safety screen (may still do behavioral studies)
Neurology, Language & Linguistics, Vision & Eyes
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Location
Hershey, PA

A randomized double-blind placebo controlled trial to assess the effectiveness of low-dose naltrexone in combination with standard treatment in women with chronic pelvic pain secondary to endometriosis.

Pelvic pain associated with endometriosis is in part due to inflammation of a layer of tissue in the abdomen (stomach area). This leads to the great potential of relieving endometriosis related pelvic pain in a non-narcotic medication by decreasing the inflammation. The purpose of this study is to evaluate how a low dose of naltrexone compared to placebo (inactive substance) impacts your daily pain and the quality of your life with endometriosis. Naltrexone is approved by the U.S. Food and Drug Adminstration (FDA) for the treatment of opioid overdose and addiction. At much lower doses, naltrexone has been shown to be beneficial in pain relief of inflammatory disorders with promising results, but the use of the low dose in this study to treat endometriosis pain is investigational and has not been approved by the FDA.
Heidi Watts at hwatts@pennstatehealth.psu.edu or 717-531-6272
Female
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03970330
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Inclusion Criteria:
Surgical diagnosis of endometriosis within last 10 years
Pelvic Pain associated with endometriosis
age 18-45
Exclusion Criteria:
Daily opioid use
Pregnant
Breast Feeding
Allergy to oxycodone, motrin, naltrexone
Pain Management, Women's Health
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Location
Hershey, PA

A Phase 1b-2 Study to Evaluate Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Various Regimens of Erdafitinib in Subjects with Metastatic or Locally Advanced Urothelial Cancer

The purpose of this study is to see whether taking the drug Erdafitinib and the drug JNJ-63723283 is safe and effective in treating patients with advanced bladder cancer.
Kathleen Rizzo at kar23@psu.edu or 717-531-0003, ext=289630
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03473743
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Inclusion Criteria:
≥18 years of age.
Histologic demonstration of transitional cell carcinoma of the urothelium.
Stage IV disease (metastatic or Locally Advanced cT4b, N+, or M+ cancer).
Meet appropriate molecular eligibility criteria
Documented progression of disease per RECIST 1.1, defined as any progression that requires a change in treatment, prior to randomization.
Exclusion Criteria:
Treatment with any other investigational agent or participation in another clinical study with therapeutic intent within 30 days prior to Cycle 1 Day 1. For Phase 1b, subjects who have received the following prior antitumor therapy
Chemotherapy within 3 weeks of Cycle 1 Day 1
Prior anti-PD-1, anti-PD-L1, or anti-PD-L2 therapy
Active malignancies (ie, requiring treatment change in the last 24 months) other than urothelial cancer (except skin cancers within the last 24 months that are considered completely cured).
Symptomatic central nervous system metastases.
Cancer
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Location
Hershey, PA

Site for Randomized Phase II/III Trial of Radiotherapy with Concurrent MEDI4736 (Durvalumab) vs. Radiotherapy with Concurrent Cetuximab in Patients with Locoregionally Advanced Head and Neck Cancer with a Contraindication to Cisplatin

The purpose of this study is to compare any good and bad effects of usual radiation plus the study treatment drug (durvalumab), to the usual therapy of radiation plus the drug (cetuximab) in patients with head and neck cancer who cannot take the drug cisplatin.
Irina Geier at iug29@psu.edu
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03258554
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Inclusion Criteria:
squamous cell carcinoma
18 or older
Adequate hematologic function
Adequate hepatic function
Adequate renal function
Exclusion Criteria:
invasive malignancy within the past 3 years
Prior radiotherapy
Prior immunotherapy
Major surgery within 28 days prior to Step 1 registration
Uncontrolled hypertension
Cancer
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Study Locations

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Location
Hershey, PA

Assessment of Endothelial Function in Post-Menopausal Women with Depression

The goal of this project is to understand the contribution of depression on blood vessel function in post-menopausal women, a population at heightened risk for cardiovascular disease. Currently, little is known about the combined impact of depressive symptoms and the effects of reproductive aging on blood vessel function. As such, there is a greater need to characterize blood vessel function in post-menopausal women with depressive symptoms. Participants depressive symptoms will be assessed and non-invasive vascular measures will be performed.
Jigar Gosalia at jzg691@psu.edu or 814-863-3182
Female
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Post-menopausal women who are at least 1 year removed from their final menstrual period and between the ages of 50 and 80
Postmenopausal women with moderate to severe depression
Non-depressed post-menopausal women are needed as well for control group comparisons
Free from blood-pressure lowering medication and lipid lowering medication
Exclusion Criteria:
Individuals with any overt cardiovascular, metabolic, hematologic, pulmonary, renal, musculoskeletal, and/or neurological disease(s).
Users of any tobacco and/or nicotine products (smokers, chewing tobacco, nicotine-containing patches/gum, smokeless cigarettes)
Individuals taking hormone therapy
Individuals with a BMI > 35
Heart & Vascular, Mental & Behavioral Health, Women's Health
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Study Locations

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Location
State College, PA

Epigenetics and Bipolar Disorder: The Role of Reelin in Bipolar Disorder

This study is designed to compare biological markers of mood in participants with bipolar disorder to individuals without bipolar disorder. Participants will answer questions, give blood, and undergo a clinical interview. This study is a 1 time appointment lasting no longer than 1.5 hours and participants will be compensated $50.
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Healthy Control
18 Years or Older
No diagnosis of psychiatric disorder
Exclusion Criteria:
Diagnosis of autism spectrum disorder, substance use disorders, schizophrenia or other psychotic disorder
Pregnancy
Investigator discretion regarding ability to participate in the study
Mental & Behavioral Health
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Study Locations

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Location
Hershey, PA

Multidisciplinary Collaboration as a Bridge to the Ethical Collection of Patient-level Data on Social Determinants of Health (SDoH)

The purpose of this study is to create a tool that will evaluate a patients social determinants of health, which is the environment in which someone is born, works and lives. This tool could provide information to physicians that could help the patient avoid negative health outcomes.
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Adult 18+
Patient at Penn State Health OR Community Member
Can read and write in English
Exclusion Criteria:
Inability to make their own decisions/consent
prisoner
Brain Injury
Education
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Study Locations

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Location
Harrisburg, PA
Hershey, PA

fMRI based mapping of the supraspinal projections of the exercise pressor reflex

This study will examine how the brain controls blood pressure responses during exercise, and will include 3 separate visits. In one visit, you will perform a series of handgrip exercises followed by inflation of a blood pressure cuff while we collect muscle nerve activity and blood pressure. In the other two sessions you will perform a similar task while laying in an MRI machine.
Aimee Cauffman at acauffman@pennstatehealth.psu.edu or 717-531-1617
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
age between 21 and 40 years
healthy
able to perform handgrip execise
normal blood pressure
Exclusion Criteria:
claustrophobic
have metal implants
taking heart medication
pregnant/nursing
smoker
Heart & Vascular
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Study Locations

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Location
Hershey, PA

Seeking support from romantic partners

The purpose of this study is to determine whether and how people's perceptions of the power in their romantic relationships shape the messages they use to seek support from their romantic partners.
Andy High at ach208@psu.edu or 814-863-3969
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Are you currently in a romantic relationship?
Have you sought comfort, advice, information, esteem boosts, or emotional support from your romantic partner within the last 4 weeks?
Exclusion Criteria:
People who are under 18 years old
People who are not in a romantic relationship
People who did not seek support from their romantic partner in the last 4 weeks.
People who do not have access to technology to compete the survey.
Mental & Behavioral Health, Language & Linguistics
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Recruitment for Nicotine and Tobacco Related Research at Penn State Hershey

The purpose of this project is to screen potential participants for multiple research studies being conducted by tobacco researchers at Penn State Hershey. Since there are multiple IRB approved studies enrolling at Penn State Hershey with similar but not identical inclusion/exclusion criteria, it is more efficient for the researchers and participants to have one phone number to call initially for basic screening. After completing this, the participant can be redirected for more specific screening if they are found to be potentially eligible for one of the studies.
Candace Bordner at cbordner@phs.psu.edu or 844-207-4594
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Age 21 or older
Current tobacco user
Exclusion Criteria:
Age less than 21
Addiction & Substance Abuse, Lung Disease & Asthma
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Study Locations

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Location
Harrisburg, PA
Hershey, PA
York, PA

Understanding the Media Literacy Competencies of Today’s College Students

This study will involve surveying college students regarding their media literacy competencies and experiences with media literacy education.
Hans Schmidt at hcs10@psu.edu or 610-892-1251
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
College student
18 years of age or older
Exclusion Criteria:
Not 18 years of age or older
Education
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Social Values for Bird Conservation in PA

The purpose of this study is to examine public attitudes and willingness to pay for bird conversation activities on private forest lands.
Melissa Kreye at mxk1244@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
lives in Pennsylvania
Exclusion Criteria:
Does not live in Pennsylvania
Education
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Learning about Girls’ Emotions Study

In this study, we hope to better understand whether certain behaviors, reactions and feelings associated with Borderline Personality Disorder (BPD) are found in girls, and how these things may or may not be related to ADHD and brain activity patterns. BPD is a condition that usually is found in adults, and is linked to emotional and behavior problems in children. In doing so, we are asking girls between the ages of 8-12 years and their parents to participate in our research.
Attention and Behavior Clinic Research Group at abc@pennstatehealth.psu.edu or 717-531-0003, ext=285966
Female
Younger than 18 years old
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Ages 8-12 years
Female
With or without ADHD Diagnosis
Speak fluent English
Exclusion Criteria:
Younger than 8 years old
Older than 12 years old
Male
Neurology, Mental & Behavioral Health
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Study Locations

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Location
Hershey, PA

Collaboration and moderation in online games

The project seeks to use empirical methods such as interview and survey to understand how game players collaborate in video games (e.g., how they work together to kill a monster in game), when breakdowns happen in collaboration (e.g., they blame each other when they fail to achieve their in-game goal), and what moderation mechanisms could be used to enhance collaboration (e.g., mechanisms that discourage them from harassing their teammates).
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
The proposed study will involve adults no less than 18 years old who have played online games.
Participants need to speak English.
Exclusion Criteria:
Vulnerable populations such as pregnant women, children, cognitive impaired adults, and prisoners.
People who have never played online games.
People who are less than 18 years old.
People who do not speak English.
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Barriers to Transgender Healthcare in Rural Communities

The purpose of this study is to comprehensively explore the barriers to healthcare among rural transgender or non-binary adults in rural Pennsylvania, using a convergent mixed-methods approach.
Oluwamuyiwa Adebayo at owa2@psu.edu or 814-867-4656
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Aged 18 years and older
Identify as transgender or non-binary or genderqueer
Fluent in English
Reside in Rural Pennsylvania County
Exclusion Criteria:
Younger than 18 years
Identify as cisgender
Men's Health, Prevention, Women's Health
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Speech Production in Noise

This study aims to investigate the effect of background noise on speech production. Participants will be asked to describe an image or concept while their speech is recorded.
Catherine Pham at catherine.pham@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
18 years of age or old
Native monolingual English speaker
Minimum high school education
Normal or corrected-to-normal vision/hearing
Exclusion Criteria:
Those unable to consent, pregnant women, children, and prisoners will be excluded
Under 18 years of age
Non-native monolingual English speaker
Less than high school education
Non-normal vision/hearing
Language & Linguistics
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Study Locations

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Location
State College, PA

Examining views associated with physical exercise and its connection to diet, social connectivity, and stress reduction: Online Focus Groups

The primary objective of this study is to examine, via online focus groups, the perceptions that are held by potentially-eligible subjects in the PSH DPP program in regard to the importance of physical exercise, particularly within the context of diet, social connectivity, and stress reduction. These perspectives will then be used to help develop, test, and refine additional motivational text messages that can be used in a text messaging intervention. Participants will receive a $25.00 gift card.
Selena Ortiz at suo13@psu.edu or 814-863-8041
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Be at least 18 years old and under age 65
Body Mass Index ≥25 kg/m2 (≥23 kg/m2 if Asian)
Have no previous diagnosis of type 1 or type 2 diabetes
Fluent in English
Exclusion Criteria:
Under 18 years old and over age 65
Body Mass Index <25 kg/m2 (<23 kg/m2if Asian)
Previous diagnosis of type 1 or type 2 diabetes
Not fluent in English
Prevention, Education, Diabetes & Hormones
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Understanding the Experiences of College Students of Color with Psychiatric Disabilities

The purpose of this study is to develop a better understanding of the lived experiences of college students of color with psychiatric disabilities, particularly related to the formation of racial identity, disability identity, and the impact of perceived discrimination.
Amber O'Shea at amo5208@psu.edu or 814-867-5721
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
Hide eligibility criteria
Inclusion Criteria:
Currently enrolled as a college student
18 years of age or older
Capable of providing informed consent
Diagnosis of a psychiatric disability
Identify as a person of color
Exclusion Criteria:
Adults unable to provide legal consent
Individuals who are not yet legal adults
Prisoners
Unable to speak/read English Language at time of interview
Addiction & Substance Abuse, Education, Mental & Behavioral Health
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Study Locations

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Location
State College, PA

Identification of Critical Thermal Environments for Aged Adults

The earth’s climate is warming, and the number of heat waves has increased in recent years. At the same time, the number of adults over the age of 65 is growing. Humans sweat and increase blood flow to the skin to cool their body when they get hot. Older adults do not do this as well as young adults. This makes it harder to safely exercise in warm and/or humid conditions. It is important to learn about safe limits of heat and humidity for older adults to exercise. Also, nearly 40% of adults over age 50 take aspirin to lower their risk for heart disease. Our lab has shown that aspirin lowers the control of body heat. In this study, we will determine critical temperature and humidity environments above which normal body temperature cannot be maintained in young and older adults. We will also look at how aspirin may change critical temperature and humidity thresholds in older adults.
Susan Slimak at sks31@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Healthy subjects 18-30 or 65-85 years of age
Non-obese
Normal blood glucose (HbA1C <5.7%)
Normal cholesterol (LDL cholesterol <180 mg/dl)
Asymptomatic and no signs/symptoms of disease
Exclusion Criteria:
Have any conditions to advise against low-intensity physical activity
Received a prior diagnosis of cancer, cardiovascular disease, diabetes, or metabolic syndrome
Medications that could alter cardiovascular responses or body temperature regulation during exercise (blood pressure reducers, fever reducers, anti-depressants, etc.)
Tobacco or recreational drug use
Post-menopausal women taking hormone replacement therapy
Heart & Vascular, Sports Medicine
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Study Locations

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Location
State College, PA

Developing a Recommendation System for Local Community Events

In this study, we investigate a recommender system for public, local events in Centre County, PA. Currently, there is no platform that aggregates all the events that take place in a community. The data is fragmented among many platforms and it can be difficult for people to find interesting things to do. Participants will interact with our software system and discuss their experiences through a survey and/or interview.
Tiffany Knearem at tak54@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Must be 18 years or older
Must be a University Park student or local resident of Centre County
Exclusion Criteria:
Persons under 18 years of age
Persons who do not live in Centre County, PA
Education
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Study Locations

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Location
State College, PA

An open-label, multinational study of fitusiran prophylaxis in male pediatric subjects aged 1 to less than 12 years with hemophilia A or B.

A study to confirm the appropriate dose of fitusiran when given to severe Hemophilia A or B patients with inhibitors between the ages of 1 and &lt;12 years old.
Male
Younger than 18 years old
This study is NOT accepting healthy volunteers
NCT03974113
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Inclusion Criteria:
Severe hemophilia A or B (FVIII <1% or FIX ≤2%)
Inhibitory antibodies to FVIII or FIX
Age 1 to <12 years
Exclusion Criteria:
AT activity <60% at screening
Co-existing thrombophilic disorder
Central or peripheral indwelling catheter, with a hx of venous access complications
Anticipated need of surgery during the study
Presence of clinically significant liver disease
Blood Disorders
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Location
Hershey, PA

Gait Variability Due to Ankle Stiffness Imposed by an Exoskeleton

Using an exoskeleton to investigate the effects of changing ankle stiffness on parameters that predict fall risk. Subjects walk on a treadmill wearing an exoskeleton controlled to act with a certain stiffness.
Dave Schmitthenner at dhs5071@psu.edu or 585-313-1131
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
BMI under 30.
Normal Ankle function.
Calf width less than 5 inches, sitting knee height greater than 16 inches, shoe size less than men's 10 and women's 12.
Able to walk for 10 minutes at a time without assistance.
Able to walk for at least 45 minutes total within 2.5 hours.
Exclusion Criteria:
Previous or existing neurological pathologies, injuries or illnesses likely to affect gait.
History of neuromuscular disorders or lower limb joint replacements.
Currently taking blood thinners (small risk of bruising).
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Location
State College, PA

User experience with smart devices

This study investigates users’ experience with smart devices. This study makes further implications for designing more user-friendly devices for better user experience. We aim to make such contributions by answering these questions: 1. How do users interact with smart devices? 2. What challenges do users face when using smart devices? 3. What strategies do users apply to adapt themselves to smart devices? 4. What service do smart device producers provide for users to get a better user experience? 5. When does user experience break down when interacting with smart devices? The study methods are social media data analysis, interview, survey, and focus group.
Yao Lyu at yml5549@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
18 years or elder
all genders included
have prior experience with smart devices
Exclusion Criteria:
younger than 18 years old
all vulnerable populations, such as pregnant women, cognitive impaired adults, and prisoners.
no prior experience with smart device
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Study Locations

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Location
State College, PA

Effect of oral black raspberry administration on oral cell DNA adducts in smokers

This is an intervention study that will examine the effect of black raspberry lozenges on mouth cell DNA damage in smokers.
Nicolle Krebs at nkrebs@pennstatehealth.psu.edu or 717-531-5673
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Smokers (cigarettes per day or more)
No plans to quit smoking in next 4 months
Healthy
Willingness and ability to attend 4 visits over 14 weeks
21-65 years of age
Exclusion Criteria:
Unstable or significant medical condition
Women who are pregnant or nursing
Use of marijuana or other illegal drugs
Any known allergy to raspberries
Heavy drinking (>4 drinks/day, 5 days/wk)
Prevention
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Study Locations

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Location
Hershey, PA

Novel Therapies to Improve Cardiac and Skeletal Muscle O2 Supply-Demand Mismatch in Older Adults with Peripheral Arterial Disease: Esmolol infusion

This research is being conducted to determine how oxygen delivery to the heart and leg muscles is altered when beta-1 receptors (receptors involved in the “fight or flight” response) are temporarily blocked through a medication infused into an arm vein (compared to when a simple saline solution is infused). This will help us determine whether the medication, Esmolol, a beta-1 blocker, can eventually be used in the evaluation or treatment of PAD.
Aimee Cauffman at acauffman@pennstatehealth.psu.edu or 717-531-1617
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT04181606
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Inclusion Criteria:
Men and women age 21-85 years
Healthy
Not currently taking medications affecting heart rate or contractility
Exclusion Criteria:
Females who are pregnant or lactating
Bleeding or clotting disorder
HIstory of angina or recent heart attack
Diabetes or hypertension
Heart & Vascular
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Location
Hershey, PA

The effectiveness of a community-based steps challenge on cardiovascular health outcomes in previously sedentary adults

The purpose of this study is to determine the effect of Blair County’s Active Living Steps Challenge on cardiovascular health in physically inactive adults participating in the intervention compared to a control group of adults also living in Blair county who are not participating in the Steps Challenge.
Nicole Gilbertson at nmg46@psu.edu or 814-949-5016
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Males and Females
Ages 18-65 years old
Currently living and/or working in Blair County, Pennsylvania
Not currently participating in planned, structured physical activity at least 30 minutes at moderate intensity on at least 3 days/week for at least 3 months
Ability to walk for >10 minutes at a time
Exclusion Criteria:
Known cardiovascular disease, chronic obstructive pulmonary disease, cancer, diabetes, or renal disease
Conditions associated with cognitive impairment or medical instability that puts the subject at risk
Signs or symptoms suggestive of cardiovascular, metabolic, or renal disease
Females currently pregnant or breastfeeding
Currently involved in a program to gain or lose weight
Heart & Vascular, Prevention
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Study Locations

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Location
Altoona, PA