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417 Study Matches

Explaining Preference Elicitation Process in Health Recommendation Systems

Our research explores the possible solutions to explaining preference elicitation processes in health recommendation systems, including a range of advanced intelligent user interfaces (UI) to support exploration, transparency, explainability, and controllability of health recommendations (Chen et al, 2016).
Chun-Hua Tsai at ctsai@psu.edu or 814-865-4558
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
1. The proposed study will involve adults no less than 18 years old.
2. Efforts will be made to include both men and women.
3. Participants need to speak English.
4. No vulnerable populations will be included.
Exclusion Criteria:
1. Vulnerable populations such as children, pregnant women, cognitively impaired adults, and prisoners.
2. People who have never used recommendation systems.
3. People who are less than 18 years old.
4. People who do not speak English.
Education
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State College, PA

In Alexa, we Trust. Or do we ? : A Case Study of Privacy Policies of Amazon's Intelligent Voice Assistant

Trying to understand how humans alter their behavior when presented with new information regarding privacy rules.
Sanjana Gautam at sqg5699@psu.edu or 814-867-5787
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Must be 18 years of age or older
Must own a smart home device
Exclusion Criteria:
Most not be younger than 18 years of age
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How do cues from the environment affect sound perception?

This study is about investigating how certain elements of urban configuration affects people's subjective perception of noise in urban environments. This section of the study assesses participants' subjective reactions to noise intensity when the tree density changes in various spaces.
Sohail Sadroleslami at sbs5622@psu.edu or 814-883-7773
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Age: 18 -24
Gender: all
no visual or hearing impairments
Exclusion Criteria:
no visual or hearing impairments
Vision & Eyes
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Study Locations

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Location
State College, PA

Better Together: Understanding Family Engagement in Early Childcare Education Centers in Central Pennsylvania

The purpose of this study is to use a short survey to understand family involvement in early childcare education centers throughout central Pennsylvania (Dauphin, Lancaster, and Lebanon counties). This understanding will help to better engage families and promote child health and wellness.
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Adult parents/guardians of infants/toddlers that attend an ECEC.
The ECEC is located in either Dauphin, Lebanon, or Lancaster county.
Must have an email account.
Must have access to a mobile phone, tablet, desktop or laptop computer to complete survey.
Parent/guardian must be able to fluently read and understand English.
Exclusion Criteria:
Parents/guardians less than 18 years old.
Children's Health, Education, Mental & Behavioral Health
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COVID-19 in Pregnancy Study

We are interested in learning more about how COVID-19 impacts the health of moms and their babies from pregnancy to the first month of life. This study will help us gather more evidence that could guide the clinical care provided to moms and their babies.
Kristin Sznajder at ksznajder@phs.psu.edu
Female
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Pregnant
>=18 years
Seeking care at Penn State Health
Exclusion Criteria:
Not planning on being a caregiver to the infant after it is delivered
Children's Health, Pregnancy & Infertility, Women's Health
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Social Distancing Well-Being Study

We are seeking volunteers to help us learn more about the implications of social-distancing and staying home during a pandemic.
Natasha DeMeo at nnd7@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
18 years or older
Living in the United States
Able to read/write in English
Social distancing for at least the past week
Exclusion Criteria:
Working more than 40 hours per week (i.e., overtime) outside of the home over the past week
Mental & Behavioral Health
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The Muscle Reflex: MRI Studies

This research is being done to examine how the response to leg exercise measured with MRI is different between patients with Peripheral Arterial Disease (PAD) and healthy volunteers.
Cheryl Blaha at cblaha@pennstatehealth.psu.edu or 717-531-1605
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
At least 21 years old
healthy
•no major medical concerns
women and men of all races
Exclusion Criteria:
have a chronic medical concern
females who are pregnant or lactating
have ferromagnetic metal implants
are claustrophobic
Heart & Vascular
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Location
Hershey, PA

Psychopathy and Affective Priming

This is a study which examines whether priming for fear can influence affective empathy in persons high in psychopathic traits.
Daniel Komar at dzk231@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Adults over the age of 18
Able to read and write in English
Exclusion Criteria:
Persons unable to read and write in English
Persons under the age of 18
Mental & Behavioral Health
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COPE Study: COVID-19 and Perinatal Experiences

This two-component observational study aims to assess and address the needs of women who are pregnant during the COVID-19 pandemic, as pregnant women are likely to experience different stressors compared to non-pregnant women. For the cross-sectional portion of the study, participants will be asked to complete an online survey that asks questions about their experiences related to being pregnant during COVID-19; the survey will take about 25 minutes to complete. For the optional longitudinal portion of the study, participants will be asked to take three additional online surveys which will take about 25 minutes each to complete.
Jenna Knepp at devriskandres@psu.edu
Female
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Pregnant or parenting a child 6 months of age or less
18 years or older
Female
Exclusion Criteria:
Cannot speak either English or Spanish
Pregnancy & Infertility
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CCTG MA.39- A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive Breast Cancer

Purpose of this study is to compare any good and bad effects of not using regional radiotherapy to using radiotherapy. The study will help researcher learn if not giving regional radiotherapy is just as good as using regional therapy to treat node positive breast cancer in women.
Michelle Eschbach at meschbach@pennstatehealth.psu.edu or 610-378-2336
Female
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03488693
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Inclusion Criteria:
Estrogen Receptor Positive / Her2 Negative Breast Cancer
No evidence of metastasis
1
•3 positive lymph nodes
May have had breast conserving surgery or mastectomy
40 years of age or older
Exclusion Criteria:
Nodal disease limited to micromets or isolated cells
History of ipsilateral breast cancer or DCIS
Synchronous or contralateral breast cancer
pT3 or pT4 disease
Neoadjuvant Chemotherapy for breast cancer
Cancer
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Location
Reading, PA

Site for PD-INHIBITOR (NIVOLUMAB) AND IPILIMUMAB FOLLOWED BY NIVOLUMAB VS. VEGF TKI CABOZANTINIB WITH NIVOLUMAB: A PHASE III TRIAL IN METASTATIC UNTREATED RENAL CELL CANCER [PDIGREE] (PSCI# 19-109) (A031704)

The purpose of this study is to compare the usual treatment of advanced kidney cancer (treatment with ipilimumab and nivolumab followed by nivolumab alone) to the usual treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib. This study will help the study doctors find out if this different approach is better than the usual approach. To decide if it is better, the study doctors will be looking to see if adding cabozantinib to nivolumab can increase the percentage of patients alive at 3 years from 60% to 70%.
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03793166
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Inclusion Criteria:
Histologic documentation of renal cell carcinoma with clear cell component
Age ≥ 18 years
Karnofsky performance status greater than or equal to 70%
Hemoglobin ≥8 g/dL
Platelet Count ≥ 100,000/mm3
Exclusion Criteria:
No prior previous systemic therapy for renal cell carcinoma.
No cancer therapy less than 28 days prior to registration; this includes radiation therapy.
Not pregnant and not nursing, because this study involves an agent that has known genotoxic, mutagenic, and teratogenic effects.
No history of HIV or active hepatitis B/C, or tuberculosis
No uncontrolled hypertension (systolic BP >150mmHg or diastolic BP
Cancer
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Location
Hershey, PA

Beneficial effects of moderate heating on cardiovascular control in heart failure

The purpose of this project, is to examine if moderate whole body heating will effect the resting muscle sympathetic nerve activity (MSNA) and the MSNA response to the stimulation of muscle mechanoreceptors in chronic heart failure patients.
Cheryl Blaha at cblaha@pennstatehealth.psu.edu or 717-531-1605
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
non-smoker
Heart failure patients
•may be on medications
Healthy subjects
•no blood pressure or cholesterol meds
Exclusion Criteria:
pregnant or nursing women
uncontrolled blood pressure
recent heart attack in past 6 months
on kidney dialysis
Heart & Vascular
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Location
Hershey, PA

Perception of English sentences in context

This study tracks the eye movements of 30 adults to gather information on how they process sentences when presented in a context.
Frances Blanchette at fkb1@psu.edu or 814-863-7392
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
adult (18+)
native speaker of American English
grew up mainly in the US
Exclusion Criteria:
under 18 years of age
not a native speaker of American English
did not grow up mainly in the US
Language & Linguistics
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Study Locations

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Location
State College, PA

Dining with Diabetes in Pennsylvania

Penn State Extension's Dining with Diabetes program is an evidence-based community education program for people with or at risk for type 2 diabetes. The program teaches participants how to prevent or manage their disease by providing practical knowledge and strategies to make the necessary lifestyle changes that will lead to healthier living and reduction in the risk of complications. The overall goals and objectives of the program are as follows: Increasing knowledge of healthy food choices for families with or at risk for diabetes Promoting behavior changes by offering demonstrations and tasting of healthy food. Increasing knowledge of essential medical tests associated with diabetes management. Promoting physical activity as a component of diabetes control. Encouraging self-management and self-efficacy skill. Connecting participants to their healthcare providers for long-term follow-up. The program is designed to meet 4 consecutive weeks and then a 3 month follow-up. Classes consist of a nutrition lesson, physical activity, cooking demonstration and food tasting.
Debra Griffie at dab210@psu.edu or 610-489-4315
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT04080960
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Inclusion Criteria:
Individulas with type 2 diabetes
individuals with pre-diabetes
individuals at risk of developing type 2 diabetes
healthy family members/caretakers
healthy volunteers
Exclusion Criteria:
under the age of 18
Diabetes & Hormones
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Altoona, PA
DuBois, PA
Erie, PA
Greater Pittsburgh Area, PA
Hazleton, PA
Reading, PA
State College, PA
Wilkes-Barre/Scranton Area, PA

The peripheral vascular effects of sulfhydryl-containing antihypertensive pharmacotherapy on microvascular function and vessel remodeling in hypertensive humans

High blood pressure can cause physical changes to the blood vessels of the body (remodeling). If a person who has high blood pressure also has a lot of blood vessel remodeling with their condition, they are more likely to have poor results with medical treatment for hypertension. We examine the impact of different classes of drugs that doctors use to treat high blood pressure (hypertension) on blood vessel remodeling. Some drugs that doctors prescribe for their patients contain a “sulfhydryl group” (a sulfur atom bonded to a hydrogen atom). Drugs that have the sulfhydryl group may reduce blood vessel remodeling more that drugs that do not. For this study, participants who have high blood pressure perform the experiments, take a drug for 16-weeks to lower blood pressure, and repeat the experiments. We randomly assign one of three drugs to participants who have high blood pressure: a diuretic (“water pill”), a drug containing a sulfhydryl group, or a drug that does not contain a sulfhydryl group. Participants who do not have high blood pressure perform the experiments, but do not take any of the drugs. In some of our experiments, we use a technique called “microdialysis” (MD). With MD, we perfuse some research drugs into the skin on the forearm through tiny tubing that mimics capillaries. These MD drugs mimic or block substances the body naturally makes to control the small blood vessels in the skin. The drugs remain in nickel-sized areas around the tubing and do not go into the rest of the body. We also analyze very small skin samples (skin biopsy) obtained from the forearm. Lastly, we use a standard technique called “flow mediated dilation” (FMD) that uses blood pressure cuffs and ultrasound to look at the health of larger blood vessels in the body. FMD includes placing a small tablet of nitroglycerin under the tongue during part of the test.
Susan Slimak at sks31@psu.edu or 814-863-8556
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT03179163
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Inclusion Criteria:
Women and men
40-65 years
May or may not have high blood pressure
Women who are post-menopausal are not taking hormone replacement therapy
· May or may not be taking a drug to lower blood pressure
Exclusion Criteria:
Current medications which could conceivably alter the cardiovascular or thermoregulatory control or responses (e.g. beta blockers, calcium channel blockers, ACE inhibitors, angiotensin receptor blockers)
Allergy to latex
Use of tobacco products
Use of illegal/recreational drugs
Pregnancy or breastfeeding
Heart & Vascular
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State College, PA

Regional Brain Manganese Accumulation and Functional Consequences in Welders

This study is looking at the effects of welding fumes on brain health. Our group has found brain structure and functional changes using brain MRI and other tests for movement and function in active welders. Now, we are very interested to see if the brain function and structural changes persist in welders, particularly after they retire. This is an independent study sponsored by the National Institute of Environmental Health Sciences, with no affiliation to any private entities such as law firms. In this study participants will be asked to undergo clinical tests (blood draw, motor examination, memory tests), complete lifestyle questionnaires, and undergo an MRI scan during a baseline visit and again for an 18 month follow-up visit.
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Welders: Boilermakers, pipefitters, etc.
Controls: No past exposure to welding
Controls: Males ages 40-70
Fluent in English
Consent to MRI
Exclusion Criteria:
Severe memory impairment or signs of dementia
Claustrophobia or unwillingness to participate in a MRI
Significant medical and neurological defects
Significant recreational drug use or alcohol abuse
Neurology
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Study Locations

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Location
Hershey, PA

Understanding Practices on Social Network Sites and Social Relationships

Social network site (SNS) use has been very integrated into our daily practices. The distinctions between offline and online social relationship management become blurred with the mediation of SNSs. We are interested in how people perceive and use SNS and engage in social relationship management, such as self-disclosure or privacy management. Users may appropriate technological features to meet their own needs and such practices may be different from how others use the sites. The discrepancy of usage may in turn influence social relationship maintenance.
Tina Yuan at tuy11@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Social network site user (Facebook, Instagram, WeChat, etc.)
18 years and older
Exclusion Criteria:
Non-social network site users
Below 18 years old
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State College, PA

Early Childhood practitioner’s knowledge and attitudes regarding reporting child abuse/neglect: iLookOut- Phase II

Despite their daily interactions with young children, little research has been conducted into early childhood practitioners’ (ECPs’) knowledge of, and attitudes towards, reporting of child abuse/neglect. Researchers have developed an eLearning Module (iLook Out for Child Abuse) created to train and inform early childhood practitioners (ECPs). Study plans to recruit ECPs to take the learning program. The learner will be asked to answer questions before and after the learning program to help the study team evaluate the effectiveness, engagement, and usability of the program. This study is the second phase of a currently approved study- STUDY00000376.
Nicole Verdiglione at nverdiglione@pennstatehealth.psu.edu or 717-531-4552
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT02225301
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Inclusion Criteria:
Early Child Care Provider (i.e. working in a Child care center, child care home, or volunteer)
Over 18 Years of Age
Exclusion Criteria:
Under 18 years of age
Children's Health, Education
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A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Intravenously Administered BIIB092 in Participants with Progressive Supranuclear Palsy

This study is for patients who have been diagnosed with Progressive Supranuclear Palsy (PSP) which is a rare brain disorder that causes serious and progressive problems with control of walking and balance, eye movement and thinking. This research is being done to see how well an investigational medicine compared to placebo and the long-term safety and tolerability of the drug in patients with PSP. The study will also measure the amount of study drug in your blood after taking the drug, determine how your immune system reacts to BIIB092 and check other areas of health and disease that may be related to the study drug.
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03068468
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Inclusion Criteria:
Patients diagnosed with Progressive Supranuclear Palsy (PSP)
Must have a caregiver who is willing to attend clinic visits with you
Be able to walk independently or with assistance (ability to take at least 10 steps with a walker or 10 steps without a walker/cane with the assistance of another person)
Able to tolerate MRI testing
Exclusion Criteria:
Presence of other significant neurologic or psychiatric disease
Diagnosis of ALS or other motor neuron disease
History of rapid eye movement sleep behavior disorder
Considering major surgery prior to study enrollment
Neurology
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Hershey, PA

Alcohol habits in daily life

This study examines alcohol-related triggers, behaviors, and habits for 5 consecutive days in the daily lives of young adults using mobile phone surveys and alcohol monitoring wearable devices.
Rachel Bomysoad at RNB82@psu.edu or 814-863-0190
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
age 21+
Exclusion Criteria:
under age 21
Addiction & Substance Abuse
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Location
State College, PA

Examining elderly traumatic brain injury and risk for neurodegeneration

The purpose of this proposal is to understand the risk factors for Alzheimer’s disease after TBI, including time since diagnosis, ethnicity, and genetic predictors. In Aim 1 the goal is to collect data in a large group of individuals with TBI to understand these interacting factors in predicting cognitive decline. Then in Aim 2, in a sub-group of individuals we use brain imaging methods in order to determine the network response associated with neurodegeneration decades post TBI. Ultimately, the ability to monitor the neural network response to injury-specific factors in combination with risk/resiliency factors (e.g., genetic, health) may bring greater precision to rehabilitation in TBI and aid in identifying patients at risk for neurodegeneration years prior to onset. Three specific aims were designed to clarify the role of neural recruitment in recovery from TBI: 


Frank Hillary at fgh3@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
>54 years of age
sustained a traumatic brain injury
Exclusion Criteria:
<55 years of age
history of neurological disorder such as stroke, epilepsy, or multiple sclerosis
history of bipolar
Neurology
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Location
State College, PA

IMpact of PRehabilitation in Oncology Via Exercise – Breast cancer

It is well known that breast cancer patients suffer from many cancer- and treatment-related side effects that all worsen overall quality of life. Besides dealing with existing treatment-related side-effects, there is the idea of prehabilitation a process on the cancer continuum of care that occurs between the time of cancer diagnosis and the beginning of acute treatment. IMPROVE-B will evaluate an exercise prehabilitation approach with regard to safety, feasibility, acceptability and effectivity in breast cancer patients (n=30) prior surgery.
Joachim Wiskemann at jwiskema@phs.psu.edu or 717-531-0003, ext=289736
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
Scheduled for breast cancer surgery
Not metastatic (stage <4)
more than 2 weeks till surgery
Exclusion Criteria:
Receiving neoadjuvant chemotherapy or radiotherapy
Pregnant
• Engaging in systematic intense exercise training (at least 1h twice per week)
Cancer
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Hershey, PA

A Phase 3, Double-Blind, Randomized, Long-Term, Placebo-Controlled, Multicenter Study Evaluating the Safety and Efficacy of Obeticholic Acid in Subjects with Nonalcoholic Steatohepatitis (NASH)

This Phase 3, double-blind, randomized, long-term, placebo-controlled, multicenter international study will evaluate the effect of OCA on histological improvements in NASH, all-cause mortality, and liver-related clinical outcomes. Primary Objective Assessed at 18 Months • To evaluate the effect of OCA compared to placebo on histological improvement in NASH by assessing the following as co-primary endpoints using NASH CRN scoring criteria: − Improvement in fibrosis by at least 1 stage with no worsening of NASH defined as no increase in hepatocellular ballooning or lobular inflammation Page 33 of 261 Protocol 747-303 Version 4: 14 Apr 2016 Page 34 Confidential and Proprietary − Resolution of NASH as defined by overall histopathological interpretation with no worsening of fibrosis 6.2. Secondary Objectives Assessed at 18 Months • To evaluate the effect of OCA compared to placebo on histological improvement in NASH by assessing the following using NASH CRN scoring criteria: − Improvement of fibrosis and NASH as a composite endpoint and as defined by improvement in fibrosis by at least 1 stage and improvement in NAFLD activity score (NAS) by at least 2 points with at least 1 point improvement each for hepatocellular ballooning and lobular inflammation − Resolution of fibrosis − Improvement in NAS by at least 2 points with no worsening of fibrosis − Improvement in each key histological feature of NASH by at least 1 point (steatosis, lobular inflammation, and hepatocellular ballooning)
laurie peiffer at lpeiffer@pennstatehealth.psu.edu or 717-531-5226
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT02548351
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Inclusion Criteria:
NASH
fibrosis stage 2 or 3
stable body weight
Exclusion Criteria:
cirrhosis
prior cancer
heptocellular cancer
hiv, hcv, hbv
hba1c>9.5
Digestive Systems & Liver Disease
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Hershey, PA

Risk-based, response-adapted, Phase II open-label trial of nivolumab + brentuximab vedotin (N + Bv) for children, adolescents, and young adults with relapsed/refractory (R/R) CD30 + classic Hodgkin lymphoma (cHL) after failure of first-line therapy, followed by brentuximab + bendamustine (Bv + B) for participants with a suboptimal response. CheckMate 744: CHECKpoint pathway and nivolumab clinical Trial Evaluation

This is is a Phase 2, open-label study of nivolumab and brentuximab for children and young adults with relapsed/refractory classic Hodgkin lymphoma.
Suzanne Treadway, MS, RN, CCRP at streadway@pennstatehealth.psu.edu or 717-531-3097
All
All
This study is NOT accepting healthy volunteers
NCT02927769
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Inclusion Criteria:
Must be 5-30 Years of Age
A confirmed diagnosis of Classic Hodgkin Disease
Failed or did not respond to initial treatment
Exclusion Criteria:
A previous allogeneic stem cell transplant
Received certain antibody therapies in the past
Cancer
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Hershey, PA

The development of face processing in children and adolescents

Adolescence is a unique developmental period that prepares individuals for adulthood. We are studying the behavioral basis of this important time, particularly in terms of how adolescents understand and think about other people. To study this important developmental transition, we are inviting typically developing adolescents (15-17 yrs) to help us with this study for a one-time session lasting approximately 1.5 hours. Participants answer questionnaires about their social relationships (including friendships and romantic relationships) and play games of face recognition. Volunteers are compensated $10/hour for their time.
Suzy Scherf at suzyscherf@psu.edu or 814-863-0159
All
Younger than 18 years old
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Native English speaker
Normal vision and hearing (with correction)
Free of neurologic, psychiatric, endocrinology disorders
Exclusion Criteria:
Family history of autism spectrum disorders (in parents or full siblings)
Children's Health, Education
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State College, PA

Measuring the impact of three types of resistant starch on fecal butyrate levels and the gut microbiome in healthy and obese individuals

This is dietary intervention trial that will examine the impact of consuming three different types of resistant starch on the gut microbiome and butyrate levels in normal weight and obese individuals. Participants will consume starch samples daily for 24 weeks, collecting weekly fecal samples that will be returned to the lab. Researchers will analyze the bacterial fermentation products in these samples, particularly butyrate and analyze the microbiome composition. This will allow identification of differences in resistant starch (a dietary fiber) processing between normal weight and obese individuals and will also determine if the three resistant starches tested have differing impacts on the microbiome and butyrate levels.
Darrell Cockburn at dwc30@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
BMI greater than 30
Exclusion Criteria:
Diagnosis of Inflammatory Bowel Disease
Diagnosis of Diabetes
Pregnant
Taking antibiotics
Food & Nutrition
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State College, PA

Lexical and sentence processing in novice L2 learners: Psycholinguistic and neurocognitive investigations

We are studying how children and adults learn second languages in the classroom. To do this, we ask children and adults to read words or sentences in English and in Spanish while we record brainwaves using noninvasive sensors. The participant wears a cap that looks like a swimmers cap with the sensors attached to it.
Katharine Donnelly Adams at kda11@psu.edu
All
Younger than 18 years old
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Adults enrolled in third semester (intermediate) Spanish
Middle school students enrolled in first year Spanish
Monolingual English speaker
Right-handed
Normal or corrected-to-normal vision
Exclusion Criteria:
Not fluent in any language other than English
History of neurological disorders
Uncorrected vision
Education, Language & Linguistics
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State College, PA

Effects of Office Noise on Annoyance and Task Performance

There are two objectives of this study: (1) to determine the characteristics of a “good” quiet workspace and (2) to investigate the effects of typical office noise on task performance. The tests will include Ambisonic presentation (aural reproduction) of recorded office soundscapes to subjects in an anechoic chamber to determine subject preference for annoyance and effects on task performance due to noises that commonly occur in open-office environments.
Zhi Zhou at zmz5181@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
18 years or older
Must have a hearing threshold of 25 dB HL (assessed during test session)
Exclusion Criteria:
Not meeting the inclusion criteria.
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State College, PA

Raising a Child with T1D and Autism: Qualitative Thematic Analysis

We have utilized a previously completed forum and blog analysis conducted as STUDY00007977 to begin to identify to successes and challenges families raising a child with both T1D and autism experience. This study seeks to expand our knowledge through conducting interviews with families recruited both online and through the clinic. By using an Interview Guide created with our themes identified thus far, we will have a chance to expand on these themes through interviews, as well as hear from families that may not use the online community. We will recruit and interview families through the diabetes online community and through Penn State Hershey--6-8 of these families will have a child with optimal glycemic control and 6-8 of these families will have a child with suboptimal glycemic control. In addition to refining themes, this effort will help us assess the reliability, credibility, and validity of what was found via forum and blog analysis.
Jessica Wright at jwright3@pennstatehealth.psu.edu
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
Able to read, write and communicate effectively in English
Caregiver (parent, grandparent, adult sibling, guardian) to a child age 5-18 years with both T1D and Autism
Telephone and internet access
Willing to consent and complete study requirements
Exclusion Criteria:
Unable to read, write and communicate effectively in English
Not a caregiver (parent, grandparent, adult sibling, guardian) to a child age 5-18 years with both T1D and Autism
No access to phone or internet
Unwilling to consent or complete study requirements
Children's Health, Mental & Behavioral Health, Diabetes & Hormones
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Application of graph theory to both resting-state and task-based fMRI data to uncover brain-behavior relationships related to therapy outcomes in aphasia

This project will use fMRI to examine changes in the brain related to behavioral therapy outcomes in persons with aphasia. We aim to recruit twenty persons with aphasia. Each participant will receive 4 MRI scans. Between scan 1 and scan 2, no therapy will be provided (10 week break). Between scan 2 and scan 3, ten weeks of word finding therapy will be provided. Between scan 3 and scan 4, no therapy will be provided (10 week break). The therapy used is abstract word retrieval training. The results of this project will help inform rehabilitation practices in aphasia.
Chaleece Sandberg at cws18@psu.edu or 814-863-2006
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
Diagnosis of aphasia
Sustained stroke at least 6 months ago
Right-handed
Native English speaker
Completed at least a high school education
Exclusion Criteria:
History of neurodegenerative disease (e.g., Alzheimer's)
History of other acquired neurological disorder (e.g., TBI)
History of developmental disorder (e.g., autism)
History of psychological disorder (e.g., schizophrenia)
Unsafe to receive MRI (e.g., pacemaker)
Neurology, Language & Linguistics
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Study Locations

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Location
Hershey, PA