The CALM Project is looking to learn how different birthing classes prepare child-bearers for parenthood. Participants attend a free birthing class between their 20th and 37th weeks of pregnancy with their partners and fill out three questionnaires during pregnancy and postpartum. Three months after their baby is born, they are video-recorded interacting with their baby in their home and have their brain scanned using MRI. We aim to understand how different childbirth classes support mothers' well-being and bonding with their babies.

Women are asked to 1.complete 3 self-report questionnaires online during pregnancy and after their baby is born (45 minutes each)2.attend a childbirth preparation class (from a few hours to a 9-week class)3.participate in 2 in-person sessions (1.5 hours each): a videorecording with their baby in the home and a brain scan using MRI at Penn State Hershey Medical Center.

$160 + free birthing class

The purpose of this study is to investigate psychobiological factors that impact the development and manifestation of eating disorder (ED) pathology in elite male and female athletes before and during their competitive season.

The purpose of this voluntary research study is to assess how changes in stress, cognitive flexibility, response inhibition, and reward delay predict the trajectory of eating disorder behaviors and associated side effects of energy deficiency from the off-season compared to the competitive season. Your participation in this study will last approximately the duration of one season of your sport, specifically 4-weeks of data collection prior to season commencement (baseline), 4-weeks of data collection during peak competition season, and 4-weeks of data collection during off-season. The total time spent in the lab will be approximately 10-14 hours. Procedures will occur three times and measurements will be taken twice following baseline measures (once during the peak competition season, once during off-season), if you agree to do so.

$50

The objectives of this study are to understand attitudes, emotional response, and behavioral intention related to receiving COVID-19 public health messaging via the Wireless Emergency Alert system.

The purpose of this study is to compare the usual treatment of the immune therapy drug atezolizumab alone, to using radiation therapy plus the usual treatment. The addition of radiation to the usual treatment could shrink your cancer or prevent it from returning. This study will help the study doctors find out if this different approach is better, the same or worse than the usual approach. To decide if it is better, the study doctors will be looking to see if the study approach increases the life of patients or extends your time without disease compared to the usual approach.

The purpose of this study is to compare the usual treatment of the immune therapy drug atezolizumab alone, to using radiation therapy plus the usual treatment.

Research study to assess visual outcomes after cataract surgery between different devices. 3 trial groups open to males and females over the age of 18 who are to undergo cataract surgery.

There will be 3 in person visits per surgery eye.Vision will be checked at 2 of these visitsCataract surgery will be done at 1 of these visits

Rates of obesity have risen sharply throughout the world over the past several decades. The increase in the availability of highly palatable, high-calorie foods may be one factor that has contributed to this trend. That is, the availability of such foods may lead to their over-consumption and corresponding weight gain. Currently, relatively little is known about how the availability of foods, per se, affects things such as the motivation to eat and the ability to resist doing so. The current study is designed to help address this knowledge gap by examining the effects of food availability in people with high levels of dietary restraint. Dietary restraint, which refers to the intention to restrict food intake deliberately in order to prevent weight gain or to promote weight, is linked to problematic patterns of eating. This project uses laboratory tasks and brain imaging to study the effects of food availability on various outcomes, including food choices, food craving, and responses in brain areas linked to motivation.

Participants will be asked to fill out some online questionnaires and complete some computerized behavioral tasks. They will be asked to attend a one-hour virtual screening/baseline session via Zoom, and a 3-hour MRI session in the Penn State campus, University Park. In the MRI session, participants will be performing on a task involving asking them to view a series of colorful food pictures inside an MRI scanner while their brain activity is being scanned.

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The goal of this research is an assessment of spirituality as a coping mechanism related to self and community stigmatization faced by gender nonconforming individuals and those in the LGBTQ+ community. Examination of discriminatory events, spiritual coping, and sense of community belonging will also be conducted.

Participants will complete a series of online questionnaires

The aim of this study is to determine the impact of cardiometabolic disease risk factors on cognitive performance and brain vascular function, as well as, to see if beetroot juice supplementation can improve these outcomes and reduce risk of cognitive decline and brain vascular dysfunction that is seen with aging and disease.

Participants with and without high blood pressure, high cholesterol, and high blood sugar will be recruited. These are all considered cardiovascular disease risk factors.Individuals without multiple cardiovascular disease risk factors will have 2 visits and complete cognitive and blood vessel function assessments. There involves a blood draw in each visit. All study assessments are non-invasive. Total compensation is $30. Individuals with cardiovascular disease risk factors will have 5 total visits and complete cognitive and blood vessel function assessments. Additionally, participants will drink beetroot juice for 4 weeks to determine the potential health benefits on cognitive, blood vessel function, and metabolic health. There will involve blood draws and all assessments are non-invasive. Total compensation is up to $170.

$30 -170

Anxiety can emerge as early as pre-school age (4-6) and is often linked to anxiety in the parent. This study will examine patterns of brain and behavioral synchrony in parent-child pairs as they complete puzzles together and other social activities.

This is a longitudinal study examining the role that parent-child synchrony and emotional modeling plays in the transmission of anxiety. Participants will complete yearly laboratory visits and 6-month follow-up visits. The yearly laboratory visits (V1,3,5) will include a battery of tasks and questionnaires, but the six-month follow-up visits(V2,4) will only include online questionnaires. Participants at both Penn State and Washington University, St. Louis will follow the same procedures.

Participating families will be given $100 at each of V1 and V3, $25 for each of the follow-ups at V2 and V4, $100 and a $50 completion bonus at V5, for a total amount of $400.

Fieldwork is a core activity in the geosciences. Immersive technologies, such as virtual reality (VR), allow for embodied experiences while not physically present at a field site or create experiences not possible in physical reality. Immersive VR (short: iVR) refers to systems using head-mounted displays to deliver 360-degree experiences. It can deliver remote and large-scale geological entities to the laboratory, allowing geoscientists to apply real-world skills and methods to explore and interact with 3D geological models. We describe a project in which we developed an iVR workbench and experience for Iceland’s Thrihnukar volcano combining satellite imagery with terrain elevation data to create a basic reconstruction of the real world, using terrain elevation terrestrial LiDAR data to provide a point cloud model of the entire magmatic-volcanic system and intensity values for the identification of rock types, and Structure from Motion (SfM) mapping to construct a photorealistic point cloud of the volcano. To reproduce fieldwork activities, this project digs deeply into the scientific workflow of geosciences research, evaluates the priorities of the major phases of geosciences fieldwork, and develops a prototype immersive workbench for direct manipulation, information retrieval, geometric measurement, and the integration of multimedia resources. This workbench offers analytic functions currently not available in the field and is expected to help making fieldwork experiences accessible, shareable, and available any time. Future developments will also allow for collaborating remotely as well as designing repositories for comparative studies.

In prior research, it was found that the major source of drivers’ feelings of lack of safety is the passenger (Almoqbel and Wohn, 2020); in this research, we aim to understand the perceptions of rideshare passengers of the drivers’ safety. We plan to interview 30 rideshare passengers from the U.S. We ask them questions about their behavior in the rideshare cars and their perception of the driver's safety. The results will provide insights into passengers’ behaviors that could be influenced by platforms to enhance the safety of both app users, the driver, and the passenger.

We are researchers to work on understanding users’ rideshare experience. If you often use rideshare apps (e.g., almost every week), such as Uber or Lyft, please consider participating in our 30 mins to 1 hours interview to share your rideshare and app usage experience. We can have a remote interview with Zoom, Discord, phone call, or Skype.

$15

This is a phase 2/3, multi-center, randomized, double-blind, study for patients with moderate to severe Crohn's disease. Subjects with refractory CD or who are intolerant to at least one current therapy will be considered. The study consists of four substudies. They are designed to investigate efficacy, safety, tolerability of etrasimod as therapy for CD.

The study consists of a screening period, a 14-week induction period, a 6-week extended induction period (if applicable), and a follow-up period. •The subject will have to go to the study center for the visits and follow the instructions the study doctor and the study team give them, and take the study medication, as directed.They are required to bring all unused study medication and packaging to each study visit. The subject should complete their eDiary every day and bring it with you to all visits. They also must remember to return your Holter monitor to the study clinic.Other tests that the subject is required to complete will include ECG, drug test, TB test at screening. Also urine and blood tests at all induction visits except day 1 extension, vital signs and physical at every visit, eye and pulmonary function tests will be done at screening.

$600

This study includes the questionnaire related to "BRITE Synergy: Developing and Validating a Framework for Measuring Resilience in Low-Income Housing in the Post-Pandemic World" which has been previously submitted. The objective of this part of the research is examining the extent to which energy burden linked to the use of inefficient appliance within the context of a changing climate can be a good proxy for community resilience and if the ongoing building electrification drive.

Participants will be asked to complete an online survey via a link that will be accessed.

10 random participants will receive $20 gif cards.

The purpose of this study is to compare any good and bad effects of using stereotactic body radiation therapy (SBRT), a technique that gives treatment in a shorter amount of time compared to the usual radiation therapy. SBRT is experimental for treating this type of cancer. SBRT uses special equipment to position a participant and precisely deliver radiation to tumors in the body. Both the study and the usual radiation treatments use daily images to guide the radiation treatment to protect normal tissue. The study treatment, treatment over a shorter amount of time, may prevent the tumor from returning but it could also cause side effects. This study will allow the researchers to know whether this different approach using SBRT is better, the same, or worse than the usual approach. To be better, the study treatment should increase the time without the cancer coming back by six months or more compared to the usual approach, and show improvements in side effects to the bladder or rectum.

The purpose of this study is to compare any good and bad effects of using stereotactic body radiation therapy (SBRT), a technique that gives treatment in a shorter amount of time compared to the usual radiation therapy. SBRT is experimental for treating this type of cancer. SBRT uses special equipment to position a participant and precisely deliver radiation to tumors in the body. Both the study and the usual radiation treatments use daily images to guide the radiation treatment to protect normal tissue. The study treatment, treatment over a shorter amount of time, may prevent the tumor from returning but it could also cause side effects. This study will allow the researchers to know whether this different approach using SBRT is better, the same, or worse than the usual approach. To be better, the study treatment should increase the time without the cancer coming back by six months or more compared to the usual approach, and show improvements in side effects to the bladder or rectum.

In this study, we are studying how listeners use information in spoken language to anticipate upcoming information. We study this in typical listening conditions (e.g., when others are speaking simultaneously).

In a single visit lasting between 60 ~ 90 minutes, you will be asked to listen to speech played over headphones and verify/click on the pictures on the screen if they are mentioned. While you do so, your gaze behavior will be tracked. At the end, we will ask you questions about your general language history and complete answer some simple questions about words and sentences.

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The purpose of this study is to create a model that can predict a quantifiable change in human trust based on the performance of artificial intelligence. This is done through a 30 turn financial simulation where participants must invest "money" in stocks while being given the option to use or not use the assistance of an artificial intelligence.

Parkinson’s disease and a number of similar conditions, such as progressive supranuclear palsy and multiple system atrophy, often look very similar clinically, particularly early in the disease. Since there is no objective way to diagnose these disorders definitively, the current practice is to follow patients over time to allow the disease to reveal itself. Evidence indicates, however, that even the best movement disorder specialist can provide the wrong diagnosis approximately 25 percent of the time. This lack of diagnostic certainty has limited both clinical practice and research. The goal of this longitudinal study is to determine whether specific MRI and biofluid measures, such as proteins in blood and cerebrospinal fluid, can help better diagnose Parkinson’s, progressive supranuclear palsy and multiple system atrophy patients.

Participants are asked to complete a screening, baseline and 12-month visit. During the baseline and 12-month visit, participants are asked to complete some questionnaires as well as a fasting blood draw, motor evaluation, smell test and MRI. Participants also may choose to complete additional study components that ultimately may guide the diagnosis, prognosis and treatment of Parkinson's and its related disorders. These optional components include skin punch biopsies, a lumbar puncture and participation in the Translational Brain Research Center's brain donation program.

$900.00

The purpose of this study is to compare the usual treatment of advanced kidney cancer (treatment with ipilimumab and nivolumab followed by nivolumab alone) to the usual treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib. This study will help the study doctors find out if this different approach is better than the usual approach. To decide if it is better, the study doctors will be looking to see if adding cabozantinib to nivolumab can increase the percentage of patients alive at 3 years from 60% to 70%.

We are asking you to take part in a research study. We do research studies to try to answer questions about how to prevent, diagnose, and treat diseases like cancer.We are asking you to take part in this research study because you have advanced or metastatic kidney cancer.

To evaluate the effect of Saroglitazar Magnesium compared with Placebo on liver scarring in patients with NASH.

There will be 11 in person visits, various procedures will be completed such as a fibroscan, liver biopsy, blood draws and DXA scan. You will be randomly assigned by chance (like the flip of a coin) to receive either Saroglitazar 4 mg or Saroglitazar 2 mg or placebo (inactive substance).

1,325

The purpose of this study is to better understand the use and acceptance of conversational agents (CAs) aiming to support individuals with post-traumatic stress disorder (PTSD). Specifically, we will focus on examining CA prototypes that can provide useful information and support individuals with PTSD while sustaining adherence and engagement. This study corresponds to Phase 1 of the NSF grant (e.g., participatory design). The outcomes of the study will be used to advance to Phase 2 of the grant (i.e., system development"). A separate IRB application will be submitted for Phase 2. Toward this goal, we will interview individuals living with PTSD to assess the feasibility, acceptability, and correctness of the prototype of CAs.

1. Individuals who self-report having been diagnosed with PTSD2. Participants are adults, aged 18 years or older.

$30 gift card

The purpose of this research study is to compare and see if medications used in ADT treatment, either relugolix or leuprolide acetate, lower the risk of cardiovascular events in patients with prostate cancer. You (or your caregiver) will be asked to complete questionnaires electronically (such as computer, tablet, or smartphone) and/or share information via phone calls every three months until the end of your participation in the study. You will receive the study medications for treatment (either relugolix or leuprolide acetate)

Participants will be required to complete questionnaires electronically (such as computer, tablet, or smartphone) and/or share information via phone calls every three months until the end of your participation in the study. You will receive the study medications for treatment (either relugolix or leuprolide acetate)

$150 per year

This is a behavioral and neuroimaging study that will examine how food commercials affect the way a child eats and responds to food. Children enrolled in the study will complete 5 in-lab sessions that include eating meals and snacks, watching TV, and playing computer games. For one of these sessions, children will complete an fMRI scan. On the first and last visit to the lab, children will receive a DXA scan to assess their body composition.

We are looking for children to help us learn about how kids respond to different types of foods and food advertisements. The study consists of 5 visits to our facilities in Noll and Chandlee Labs, located on the University Park Campus. For 3 visits your child will eat test meals and snack buffets in our laboratory. On 1 visit we will use fMRI to take pictures of your child’s brain. We will use a DXA to scan for lean muscle and conduct an IQ test. These procedures are not harmful. You and your child will fill out questionnaires.Your child will also play computer games and watch commercials.

$250.00-450.00

This study uses a baseline assessment and 28 days of ecological momentary assessment to examine the association of emotion dynamics to craving and alcohol use among people in the first year of cessation of heavy drinking and remission from DSM-5 AUD.

There will be one in person visit. Participants will be asked to complete baseline questionnaires. After the baseline assessment, participants will complete 28 days of daily diary questions on their cell phone. A prompt will be sent to the phone 3 times per day. It should take 5 minutes (15 minutes total/day) to complete the questions.

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The purpose of this study is to examine the sexual relationships among heterosexual female college students (ages 18-22) via Qualtrics (a web-based survey). Utilizing latent class analysis with a distal outcome, the proposed cross-sectional study seeks to do the following: Aim 1. Examine the heterogeneity in relationship quality among female college students. Research question 1: Is there a latent class structure that adequately represents the heterogeneity in relationship quality among female undergraduate students participating in penile-vaginal sex? If so, what are the types and their corresponding prevalence?Aim 2. Examine the association between relationship characteristics and latent class membership.Research question 2: Are relationship characteristics (partner type, relationship duration, exclusivity/monogamy, and frequency of sex) predictive of membership in latent classes of relationship quality?Aim 3. Examine the association between latent classes of relationship quality and condom use.Research question 3: Which identified latent class of relationship quality is significantly associated with condom use at last penile-vaginal sex?Please note that the indicators measuring relationship quality will include the following variables: 1) trust, 2) love, 3) passion, 4) commitment, 5) relationship satisfaction, 6) sexual satisfaction, 7) intimacy, and 8) decision-making dominance.

A study of DFMO for patients with neuroblastoma in remission.

Participating in this study requires that you visit the Penn State health Medical Center multiple times over the course of the full study for evaluations (physical exam, blood draw, urine analysis, etc.) and scans (MRI/CT, MIBG).If you agree to take part, you will receive treatment on this study for about 2 years and will be followed for survival for 5 years after the last dose of study drug. You will be asked to return to the research site approximately 15 times.

This study will investigate whether contempt is a positive, negative, or mixed emotion.

Prediction of a subject's goal in a task based on patterns in their body language, speech, facial expressions, reaction to outcome, in short any observable measure.

This study is a phase 3 study that will be comparing recurrence-free survival (RFS) between patients withlocally advanced renal cell carcinoma randomly assigned toperioperative nivolumab in conjunction with radical or partialnephrectomy with patients randomized to surgery alone.

You are being asked to take part in this research study because you have cancer in your kidney, which is planned to be removed by a surgeon. The standard treatment for your disease is to remove the kidney or part of the kidney that contains the cancer by surgery. You are then monitored after surgery with imaging scans and exams to watch for any possiblesigns of recurrence (close observation)

The purpose of this voluntary research study is to see if neratinib, endocrine therapy, and trastuzumab completely shrink breast tumors before having breast cancer surgery. You will need to have the following exams, tests, or procedures: blood draws, ECG, Echo or MUGA, ultrasound, MRI, receive study treatment, and breast biopsy.

Participants will be required to receive study treatments, laboratory assessments, undergo breast biopsy, and radiologic assessments,

This study, part of a broader dissertation on terrorism and radicalization, aims to experimentally determine how collective punishment fuses individual identities to that of an ingroup, expanding extant knowledge of identity fusion theory.