No recent history (< 1 year) of injuries to Achilles tendon
No history of lower limb reconstruction or surgery
age 70 year or older
History of any previous surgery to lower limb
History of rheumatoid arthritis or other degenerative joint disease
Non English speaking
Inability to provide consent

Age 18 or older
Any gender
Newly diagnosed type 2 diabetes patient within the past 12 months
Have attended at least one diabetes education after diagnosis
Able to provide consent in English
Patients who are below 18 years
Patients who have a different type of diabetes either than type 2
Patients diagnosed with Type 2 diabetes more than 12 months
Newly diagnosed diabetes patients who have not attended diabetes self-management education

Histologically confirmed non-muscle invasive urothelial carcinoma of the bladder (Ta, T1, or Tis stage) on transurethral resection of bladder tumor (TURBT) obtained within 60 days of registration.
ECOG (WHO) performance status 0 or 1
Age ≥ 18 years old at time of consent
White blood cell count (WBC) > 3.0 K/mm3
Absolute neutrophil count (ANC) ≥ 1.5 K/mm3
Subjects with muscle-invasive (i.e. T2, T3, T4), locally advanced unresectable, or metastatic urothelial carcinoma as assessed on baseline radiographic imaging obtained within 60 days prior to study registration.
Subjects with another active second malignancy other than non-melanoma skin cancers and biochemical relapsed prostate cancer.
Subjects that have completed all necessary therapy and are considered to be at less than 30% risk of relapse are not considered to have an active second malignancy and are eligible for enrollment.
Subjects who have received the last administration of an anti-cancer therapy including chemotherapy, immunotherapy, and monoclonal antibodies ≤ 4 weeks prior to starting study drug, or who have not recovered from the side effects of such therapy.
Subjects who have had any prior radiation to the prostate or pelvis.

At least 21 years old
healthy
normal blood pressure
can perform 20 continuous min of cycling
Females who are pregnant or lactating
Smoker
blood pressure over 150/100
taking medications that affect the heart
unable to perform 20 continuous min of cycling

moderate to severe ulcerative colitis
failed prior treatment
women breast feeding or pregnant
no cancer in past 5 years
no Crohns disease

Subject must have an established Rare Coagulation Disorder diagnosis (
Must currently receive or have received care at and ATHN affiliated HTC
Subject must have opted into the ATHNdataset
Subject is unwilling to sign informed consent form

At least 21 years old
healthy
•no major medical concerns
women and men of all races
Females who are pregnant or lactating
have a chronic medical concern

people who livestream
people who watch livestreams
aged 13 or older (if not yet legally adults, with parental/guardian permission)
online content creators
gamers or esports viewers
under 13 years of age
cannot read, communicate or provide consent in English
does not livestream or watch livestreams or create content online
if a minor, does not have parental/legal guardian permission

HS diagnosis for at least 1 year
HS lesions in at least 2 different areas
Willing to follow all study guidelines
Certain treatments for HS are not allowed; coordinator will discuss specific treatments
Positive test results for HIV, hepatitis B, or hepatitis C

At least 21 years old
free of acute medical conditions
any race or ethnicity
women or men
have a chronic medical concern
females who are pregnant or lactating
age < 21 years old

At least 18 years of age.
Currently living in Centre County, PA.
Expecting to continue living in Centre County, PA through at least April (students) or June (community) of 2021.
Capable of providing your own Informed Consent.
Fluent in the English language.
If you have any symptoms of acute infection, you will be excluded from in-person visits until 14 days after presenting symptoms but may still be eligible for the survey portion of the research.
Individuals unable to tolerate wearing a mask (up to 60mins) may only be eligible for the survey portion of the research.
Pregnant, lactating, or planning to become pregnant in the next 12mos may only be eligible for the survey portion of the research.
Not at least 18 years of age.
Not living in Centre County, PA.

BMI between 16 and 45
Celiac diagnosis for at least 6 months
Follows a gluten free diet
Open abdominal surgery in the last 6 months
Chronic GI disease other than celiac
Received antibiotics in past 4 weeks
Diagnosis of cancer in past 5 years
Uncontrolled Type 2 diabetes

40 years and older
Hearing proficiency enough to complete a semi-structured interview
English proficiency enough to complete a semi-structured interview
History of dysphagia (swallowing disorders)
Currently on a modified dysphagia diet
Currently receiving treatment for dysphagia (swallowing problem)
Participant reports diagnosed dementia or related cognitive disorder
Participant reports any progressive neurologic diagnosis (e.g. Parkinson’s disease, Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS), etc)

Phase 1, histologically and / or cytological confirmed unresectable or metastatic solid malignancy, refractory to standard therapies with no more than three prior lines of therapy
Women of child-bearing potential (WOCBP) must have a negative serum or β-human chorionic gonadotropin (β-hCG) at screening or evidence of surgical sterility or evidence of postmenopausal status.
Abnormal c-Met dysregulation, by tissue and/or plasma, defined as the following from local/archival molecular pre-screening evaluations.
Measurable disease according to RECIST v1.1
Eastern Cooperative Oncology Group (ECOG) performance status of 0–1
Hypersensitivity to APL-101, excipients of the drug product, or other components of the study treatment regimen.
Known mutation/gene rearrangement of EGFR (except for Cohort C), ALK, ROS1, RET, NTRK, KRAS, and BRAF.
Active uncontrolled systemic bacterial, viral, or fungal infection or clinically significant, active disease process
History of, or currently, or at risk for, cardiac disease (e.g., long QT syndrome [> 450 msec QTcF or concurrent treatment with any medication that prolongs QT interval).
Impairment of gastrointestinal function or gastrointestinal disease that may significantly alter drug absorption (e.g., Crohn’s, ulcerative colitis, active inflammatory bowel disease, uncontrolled nausea, vomiting, diarrhea, or malabsorption sydrome).

Healthy pregnant women between the ages of 18 and 49
No significant fetal anomalies noted on ultrasound at at least 18 weeks gestation
HIV, syphilis, and hepatitis b negative
Planning to deliver at Hershey Medical Center
Willing to consent for infant to participate in study
Pre-pregnancy BMI >40
History of severe adverse/allergic reaction to vaccination
Current pregnancy resulting from in vitro fertilization
Current or past pregnancy complications or abnormalities

over age 18
English speaking/reading
Books a medical appointment for upper respiratory tract infection
Patient took antibiotics in the past week
Patient participated in STUDY00012891 previously
Reason for medical visit is not upper respiratory tract infection
Patient is pregnant
Patient has a medical history that includes diagnosis of any intestinal related disease

English Speakers
Between 18 and 65 years of age
Those with diagnosed speech, hearing or language issues

Cisgender women
18 and older
Selling sexual content online for a period of at least 3 months
Men
Under 18

Subjects who are 18 years of age or older
Subjects have a valid U.S. driver license or are allowed to drive in the US
Subjects who under 18 years of age
Subjects who do not have a valid U.S. driver license or are not allowed to drive in the US

Must be female
May or may not have ADHD
Has a mobile device and capable of downloading applications
Male
Not fluent in English

Must be 18 years of age or older.
Players that engage in role-play gaming using a character they have spent a significant amount of time creating.
Participants that can understand English
Participants younger than 18 years of age.
Players that do not engage in role-play gaming using a character they have spent a significant amount of time creating.
People who do not speak and read English.

Architecture Students
Architectural Engineering Students
4th or 5th year undergrads with internship experience
Graduate students
First, Second, or Third year students

Patients must have histologically documented locally advanced or metastatic urothelial (previously known as transitional cell) cancer (i.e., cancer of the bladder, renal pelvis, ureter, or urethra).
Patients in dose-escalation cohorts, Cohort A, Optional Cohort B, Cohort G, and Cohort K must be eligible for CPI therapy.
Minimum age of 18 years
Patients must have measurable disease according to RECIST Version 1.1
An ECOG performance status of 0, 1, or 2
Received any prior treatment with a CPI. A CPI is defined as a PD-1 inhibitor, PD-L1 inhibitor, or PD-L2 inhibitor (including, but not limited to, atezolizumab, pembrolizumab, nivolumab, durvalumab, or avelumab).
Ongoing sensory or motor neuropathy Grade 2 or higher.
Active central nervous system (CNS) metastases.
Ongoing clinically significant toxicity (Grade 2 or greater) associated with prior treatment (including radiotherapy or surgery).
Patients with conditions requiring high doses of steroids (>10 mg/day of prednisone or equivalent) or other immunosuppressive medications are excluded.

Pathologically (histologically or cytologically) proven diagnosis of squamous cell carcinoma of the oral cavity
Age ≥ 18
Zubrod Performance Status 0-2 within 42 days prior to registration
Only English speaking patients (able to read and understand English) are eligible to participate as the mandatory patient reported NDII tool is only available in this language
For women of child bearing potential, negative serum or urine pregnancy test within 42 days prior to registration
Definitive clinical or radiologic evidence of regional (cervical) and/or distant metastatic disease
Prior systemic chemotherapy for the study cancer; note that prior chemotherapy for a different cancer is allowable
Patient with severe, active co-morbidity that would preclude an elective or completion neck dissection
Incomplete resection of oral cavity lesion with a positive margin; however, an excision biopsy is permitted
Actively receiving systemic cytotoxic chemotherapy, immunosuppressive, anti-monocyte or immunomodulatory therapy.

Pregnant/Expecting Couples
First time parents
18 years of age or above
English speaking
Both parents cohabiting
Below 18 years of age
Not pregnant with first child
Parents not living together

HS lesions present in at least 2 locations (armpits, under breast, abdomen, groin, buttock),
Diagnosed with HS for at least 6 months
failed antibiotic treatment for HS
certain medication are not allowed; study coordinator will provide more information
Diagnosis of sarcoidosis, Systemic lupus erythematosus, or active IBD
Have had a splenectomy
Positive test result for Hepatitis B or Hepatitis C
Have had major surgery in the past 3 months

The child must be age 7-8 when the first study visit is completed
The child must not have any food allergies to foods used in the study, learning disabilities, psychological diagnoses, red/green color blindness, or claustrophobia.
The child must not be taking any medications known to influence cognitive function, taste, appetite or blood flow
The child's BMI must be below the 90th percentile at the first visit
The biological mother and father must have a BMI between 18.5-25 kg/m2 (low-risk group) or greater than or equal to 30 kg/m2 for mothers and greater than or equal to 25 kg/m2 for fathers (high-risk group) and 1 parent must attend all visits.
Children will be excluded if they are not within the age requirements (< than 7 years old or > than 8 years-old at the first visit).
Children will be excluded if they have any food allergies, learning disabilities, psychological diagnoses, red/green color blindness, or claustrophobia
Children will be excluded if they are taking cold or allergy medication, or other medications known to influence cognitive function, taste, appetite, or blood flow
Children will be excluded if their BMI is above the 90th percentile at the first visit
Families will be excluded if the biological mother or father do not fit the BMI requirements

Be in a romantic relationship
Live in State College area
Has visited at least 5 places with their romantic partner(s) in State College
Have never lived in State College area
have never engaged in a romantic relationship

Child between the ages of 6 and 17
Child has a history of physical abuse, sexual abuse, or other type of maltreatment
Child displays posttraumatic stress symptoms
Primary caregiver willing to participate in treatment
Child has a developmental or intellectual delay.
Uncontrolled allergy to or fear of dogs on part of either the child or caregiver.
CHild or caregiver has a history of aggression toward animals

Age 55-75
Postmenopausal
Not taking osteoporosis medication
Normal to low bone density
Willing to add dried plums to diet
Currently using osteoporosis medication
Other medications known to impact bone health
Extremely low or high bone density