College Student
Military Veteran
Current Member of the Military
Non-Military Civilians
Under age 18

Positive for ANA (antinuclear antibodies)
Age 18 to 49 years, inclusive
Have never taken hydroxychloroquine
Previous use of immunosuppressive drugs
Diagnosis of systemic lupus erythematosus

18-55 years of age
Right Handed
Smokes cigarettes
under 18 years of age or over 55 years of age
Left Handed
non-smokers

All Genders
All races/ethincities
Participants between 18 and 25
Participants YOUNGER than 18
Participants OLDER than 25

Children 8-13 years of age
Speak and understand English
Participation of a legal guardian
Intellectual or learning disability

Healthy throwing athletes (baseball, javelin, football)
Athletes with Ulnar Collateral Ligament Injury
Ulnar Collateral Ligament Surgery
Tommy John's Surgery
Sensibility to Ultrasound Gels

Native English speaker
Normal vision and hearing (with correction)
Free of neuroneurologic, psychiatric, endocrinology disorders
Free of concussions with loss of consciousness
Family history of autism spectrum disorders (in parents or full siblings)
History of working with metal
Irremovable metallic implants in the body (e.g. braces)
Pregnancy
Weigh more than 250lbs or get claustrophobic in small spaces

18-50 years old
No known hearing impairment
No known speaking impairment
Subjects will need to be bilingual (with varying proficiency in the second language
•beginner to advanced) or monolingual
Known hearing impairment (past or present)
Known speech impairment (past or present)
Under 18 or over 50

40 years of age or older
Patient Group: Fibrotic lung disease with chronic cough symptoms or Idiopathic cough syndrome
Healthy Control Group: no cough (either chronic or acute)
Recent history of smoking (former smokers must be tobacco-free for at least 1 year)
History of (other) lung diseases
History of uncontrolled gastroesophageal reflux disease (GERD)
Use of exclusionary medications (i.e. steroids, ACE inhibitors, narcotics, cough suppressants)
History of uncontrolled post nasal drip

Men and Women aged 18-30 and 60-80 years old
Healthy weight
Not taking high cholesterol/high blood pressure medication
Non-diabetic
Tobacco use
Illegal/recreational drug use
Pregnant or breastfeeding
Allergy to latex

Scheduled for colonoscopy in the next 4 months
age 50 and older who are undergoing their first ever screening colonoscopy
adults age 70 and older with colonoscopy more than 9.5 years ago
willing to provide blood, urine and stool samples
able to tolerate removal of 5 tubes (3.5 tablespoons) of blood
positive stool blood test (FIT/FOBT) in the past year
ever had colon or rectal cancer
history of inflammatory bowel disease
confirmed hereditary non-polyposis colorectal cancer, familial adenomatous polyposis, HIV or chronic viral hepatitis
cancer diagnosis or treatment in past year

Be willing to not start or stop any NSAID or disease modifying treatments for SLE during the study
Be wiling to not use any legal or illegal cannabinoids, including FDA-approved cannabinoids during study participation
If female of child-bearing potential must be willing to use highly effective contraception during study participation
Treatment with steroids in the past 28 days
Actively listed on organ transplant list or have received an organ transplant other than a corneal transplant
Have active or chronic infections
Have a history of cancer (except cervical treated successfully with curative therapy or basal cell carcinoma)
Have a history of significant heart disease

Between the ages of 30-65
Able and willing to undergo an MRI
Able to travel to State College for the Study
Current psychotherapy treatment for depression
Started anti-depressant medication in the last 2 months
Diagnosis of bipolar disorder, schizophrenia, or significant neurocognitive impairment
Very severe depression that would interfere with the ability to participate or suicidal ideations
Unable to undergo an MRI (metal in your body)

Hemophilia A
FVIII Level <1% or 1-2% with> 10 bleeds past 52 weeks or 1-2% on prophy treatment
Greater than 150 exposure days to Factor VIII concentrate or cryo
No evidence of Factor VIII Inhibitor
Acceptable lab values as defined by protocol
Active Hep B or C &/or current antiviral therapy for Hep B or C
Significant underlying liver disease
HIV-1 or HIV-2 with CD4 count </=l to 200
Other investigational product in the past 12 weeks or gene therapy research within the past 52 weeks
Any other significant condition/disease that in the opinion of the investigator would make the subject unsuuitable

Premenopausal female aged 18 to 50 years old
Has a diagnosis of endometriosis verified by surgery in the last 10 years
Has regular menstrual cycles (21 to 35 days long)
Has moderate, severe, or very severe pain during menstrual cycles
Is not expected to undergo gynecological surgery (or other surgical procedures for treatment of endometriosis) during the study
Has a history of chronic pelvic pain that is not caused by endometriosis
Has had 4 or more prior laparoscopic, surgical, or other invasive procedure for endometriosis
Has had gynecological surgery or other surgical procedures for treatment of endometriosis within the 3 months prior to the Screening visit
Has unexplained vaginal bleeding outside of the patient’s regular menstrual period or pregnancy
Has a gastrointestinal disorder affecting absorption or gastrointestinal motility, history of or currently has osteoporosis or a systemic autoimmune disease

Children between the ages of 5 and 12
Children diagnosed with ADHD or suspected ADHD Symptoms
Children who are able to stop ADHD medication for testing days
Parent/child fluent in English
Children younger than 5 year or older than 12 years
Children with visual or hearing deficits or sensitivity to loud noise
Neurological conditions such as active seizure disorder
Prominent traits or diagnosis of Autism, marked developmental delay, mania, psychoses, or suicidal ideation.

Journalism student
Involvement on student newspaper
Involvement with other student media
No involvement in student journalism

Children aged 8-12
Children outside of the 8-12 age range
History of seizures or photosensitive epilepsy

Patient must have a subjective memory concern as reported by patient, study partner, or clinician
Age 55-90 (inclusive)
Study Partner is available who has frequent contact with the patient (e.g. an average of 10 hours per week or more), and can accompany the patient to most visits to answer questions about the patient
Must speak English fluently
Good general health with no additional diseases/disorders expected to interfere with the study
Any use of tobacco or nicotine products within the past year
Any significant neurologic disease such as Alzheimer’s disease dementia, Parkinson’s disease, multi-infarct dementia, brain tumor, seizure disorder, etc.
History of alcohol or substance abuse or dependence within the past 2 years

Adult (aged 30-75)
Cancer diagnosis (stage 0 through 3 only)
Completed primary cancer treatment at least 3 months prior to participating
Have a scheduled or plan to schedule a follow-up cancer screening appointment in the next 30 days
Fluent in English
No cancer diagnosis, or diagnosis of Stage 4 cancer
No access to desktop/laptop computer with active internet connection
Diagnosis of psychiatric disorder AND recent hospitalization
Visual impairments that would prevent use of mobile device or computer use
Severe cognitive impairment

Adults & Children 12 years or older
Diagnoses with HAE Type 1 or Type 2
2 or more HAE attacks per month
Pregnant females or planning on becoming pregnant or nursing
Anticipated use of short-term prophylaxis for pre-planned procedure or surgery
Chest pain, heart attack, passing out or significant heart beat abnormality
Pacemaker or defibrillator implanted
Family history of sudden cardiac death not related to HAE

Over the age of 18
Have a basic proficiency of English
Physically able
Under the age of 18
Physically unable to climb stairs

>= age 13
read and speak English
neurological disorders
developmental disorders
Autism

Speak sentence length English as primary language
Normal or corrected to normal vision
Normal hearing
Individuals with and without an autism spectrum disorder or Asperger syndrome
Willing to consent and complete study requirements
Cannot speak sentence length English
Vision problems (uncorrected)
Hearing problems
Significant learning problems
Unwilling to consent or complete study requirements

Over the age of 18
Physically and mentally able
Basic proficiency of english
Under the age of 18
Unwilling to have video footage of the experiment taken

aged 18 – 24
able to speak and understand English language fluently
able to provide written informed consent
engaged in sexual activity in the past 6 months
fit into either study Group I (self-initiated STI testing) or Group II (never tested for STI) or Group III (Clinician-initiated)
Not meeting all the inclusion criteria

Age 18-60 years
Obesity (defined as body mass index between 30-40 kg/m2)
Hypertension (defined as seated blood pressure greater than 130/80 mmHg)
Able and willing to give informed consent
Pregnant or breastfeeding women
Current smokers
Type I or type II diabetes
History of major cardiovascular disease, immune or liver diseases, impaired renal or liver function
Age less than 18 years or greater than 60 years

Female adults 18 years and above with an adolescent child aged 13-16 years
Capacity for informed consent
Fluent in verbal and written English
Adolescent between the ages of 13 and 16 years (inclusive)
Diagnosis of autism spectrum disorder, substance use disorders, schizophrenia or other psychotic disorder
Any hearing or visual impairments
Investigator discretion regarding ability to participate in the study

Women following menopause
Individuals taking hormone therapy
Individuals with resting blood pressure > or = 130/80 mmHg
Users of any tobacco and/or nicotine products (smokers, chewing tobacco, nicotine-containing patches/gum, smokeless cigarettes)
Individuals with any overt cardiovascular, metabolic, hematologic, pulmonary, renal, musculoskeletal, and/or neurological disease(s)

Age > 18 years
Suspected or confirmed infection
Sepsis induced hypotension
> 4 hours from start of hypotension
> 3 L intravenous fluids
Pregnancy
Severe volume depletion
Immediate surgical intervention planned