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Here are the studies that match your search criteria. If you are interested in participating, please reach out to the contact listed for the study. If no contact is listed, contact us and we'll help you find the right person.

442 Study Matches

Identifying views of Military Veterans Regarding Contemporary War and Conflict Reporting

This study will involve surveying and interviewing US military veterans and non-veterans regarding their perceptions of the quality, accuracy, and themes of contemporary war and conflict reporting.
Hans Schmidt at hcs10@psu.edu or 610-892-1251
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
College Student
Military Veteran
Current Member of the Military
Non-Military Civilians
Exclusion Criteria:
Under age 18
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Study of Antimalarials in Incomplete Lupus Erythematosus (SMILE)

This is a study to test whether a widely-used drug, hydroxychloroquine, might slow the progression of lupus like features in individuals who are at high risk for developing systemic lupus erythematosus. This will be measured by the accumulation of clinical and laboratory features of lupus. The study will randomize subjects to the active drug, hydroxychloroquine, or placebo, with an equal chance of receiving either treatment. The study treatment lasts approximately 2 years with visits approximately every 3 months.
Jamie Carter at jcarter3@pennstatehealth.psu.edu or 717-531-4921
All
All
This study is NOT accepting healthy volunteers
NCT03030118
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Inclusion Criteria:
Positive for ANA (antinuclear antibodies)
Age 18 to 49 years, inclusive
Have never taken hydroxychloroquine
Exclusion Criteria:
Previous use of immunosuppressive drugs
Diagnosis of systemic lupus erythematosus
Arthritis & Rheumatic Diseases
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Location
Hershey, PA

Examining responses to rewards in the laboratory and during daily life in individuals who smoke cigarettes

The goal of this study is to learn more about how people who smoke cigarettes respond to rewards, such as winning money, under different conditions. The study uses a method called functional magnetic resonance imaging, or fMRI, which is a research method for measuring activity in the brain. In this study, we are using fMRI to measure how brain activity changes in people who smoke when they receive rewards. The fMRI measures are collected during two separate visits. Participants are also asked to fill out questionnaires and complete computer tasks while in the lab. In total, participants are required to visit the research lab on the University Park campus a total of five times. In addition, the study involves measuring thoughts and behaviors in people who smoke in real life by asking them to fill out surveys on a smartphone. Participants are asked to carry a smartphone for a total of 10 days and answer several surveys throughout each day. In order to be eligible for the study, individuals must be between 18 and 55 years old and you must smoke on a daily basis.
Julian Peck at jnp5021@psu.edu or 814-867-2333
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
18-55 years of age
Right Handed
Smokes cigarettes
Exclusion Criteria:
under 18 years of age or over 55 years of age
Left Handed
non-smokers
Men's Health, Addiction & Substance Abuse, Women's Health
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Study Locations

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Location
Altoona, PA
State College, PA

An Examination of Student-Mentor Relationships

This is a self-report survey and questionnaire study that examines whether members of marginalized groups are more motivated than members of dominant groups to give referent power to high status others in attempts to belonging.
Maria Sanchez at mfs5350@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
All Genders
All races/ethincities
Participants between 18 and 25
Exclusion Criteria:
Participants YOUNGER than 18
Participants OLDER than 25
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The Child Health Study

We want to understand how a child's environment affects biology in ways that impact child health
Megann Koegler at childhealthstudy@psu.edu or 888-924-4535
All
Younger than 18 years old
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Children 8-13 years of age
Speak and understand English
Participation of a legal guardian
Exclusion Criteria:
Intellectual or learning disability
Children's Health, Food & Nutrition, Education
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Study Locations

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Location
State College, PA

Evaluation of injuries in the ulnar collateral ligament (UCL) in baseball and javelin athletes

The objective of this study is to establish possible relationships between changes in the mechanical properties of the ulnar collateral ligament and symptoms and functionality of the arm in baseball players and javelin athletes. For comparison purposes, healthy subjects will also be evaluated.
Daniel Cortes at researchsubjects@mne.psu.edu or 814-863-3103
All
All
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Healthy throwing athletes (baseball, javelin, football)
Athletes with Ulnar Collateral Ligament Injury
Ulnar Collateral Ligament Surgery
Tommy John's Surgery
Exclusion Criteria:
Sensibility to Ultrasound Gels
Sports Medicine, Muscle & Bone
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Study Locations

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Location
State College, PA

Development of Adolescent and Young Adult Social Health (DASH)

Adolescence is a unique developmental period that prepares individuals for adulthood. We are studying the behavioral and brain basis of this important time, particularly in terms of how adolescents understand and think about other people. To study this important developmental transition, we are inviting typically developing children (6-8 yrs), adolescents (10-14 yrs), and young adults (18-22 yrs) to help us with this study. Participants answer questionnaires, play games of face recognition, and have pictures of their brains taken in a neuroimaging session. Child and adolescent participants also have physical exams. Volunteers are compensated for time (between $185-630) in the lab and for the neuroimaging session. If you are a parent and want to begin the screening process for you child, please go here https://pennstate.qualtrics.com/jfe/form/SV_51lN8sODiukYOON If you are an adult, and want to begin the screening process please go here: https://pennstate.qualtrics.com/jfe/form/SV_5cXMng6ybKe0WwJ
Dr. Suzy Scherf at suzyscherf@psu.edu or 814-954-0112
All
All
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Native English speaker
Normal vision and hearing (with correction)
Free of neuroneurologic, psychiatric, endocrinology disorders
Free of concussions with loss of consciousness
Exclusion Criteria:
Family history of autism spectrum disorders (in parents or full siblings)
History of working with metal
Irremovable metallic implants in the body (e.g. braces)
Pregnancy
Weigh more than 250lbs or get claustrophobic in small spaces
Children's Health, Education, Mental & Behavioral Health
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Study Locations

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Location
State College, PA

Second language speech perception and production

In this a behavioral study that will examine how second language learners perceive and produce second language speech - often in comparison to native speakers - and how these skills develop. Participants might be asked to read word lists or sentences, describe pictures or answer questions, listen to speech samples and make judgments about them (e.g. was this a real word in English? which sound did you hear?), complete a proficiency test, and fill out some background information including a language background questionnaire.
Katharina Schuhmann at kxs811@psu.edu or 814-863-7867
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
18-50 years old
No known hearing impairment
No known speaking impairment
Subjects will need to be bilingual (with varying proficiency in the second language
•beginner to advanced) or monolingual
Exclusion Criteria:
Known hearing impairment (past or present)
Known speech impairment (past or present)
Under 18 or over 50
Education, Language & Linguistics
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Study Locations

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Location
State College, PA

Evaluating the Cough Reflex in Fibrotic and Healthy Lungs

Determining cough threshold in patients with fibrotic lung disease and in healthy controls by stimulating cough.
Timothy Sheehan at tsheehan@pennstatehealth.psu.edu or 717-531-2925
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
40 years of age or older
Patient Group: Fibrotic lung disease with chronic cough symptoms or Idiopathic cough syndrome
Healthy Control Group: no cough (either chronic or acute)
Exclusion Criteria:
Recent history of smoking (former smokers must be tobacco-free for at least 1 year)
History of (other) lung diseases
History of uncontrolled gastroesophageal reflux disease (GERD)
Use of exclusionary medications (i.e. steroids, ACE inhibitors, narcotics, cough suppressants)
History of uncontrolled post nasal drip
Lung Disease & Asthma
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Study Locations

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Location
Hershey, PA

The effects of habitual physical activity on EDHF-mediated vasodilation in healthy aging

Cardiovascular disease remains the leading cause of death in the United States. Increased age is the leading risk factor for cardiovascular disease. Aging is associated with decreased vessel function. Nitric oxide, a substance produced by our bodies, is responsible for making our vessels increase their diameter and allow blood to flow. However, other substances may also cause our blood vessels to get larger. We are doing this research project to understand how physical activity affects these other substances.
Sue Slimak at sks31@psu.edu or 814-863-8556
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Men and Women aged 18-30 and 60-80 years old
Healthy weight
Not taking high cholesterol/high blood pressure medication
Non-diabetic
Exclusion Criteria:
Tobacco use
Illegal/recreational drug use
Pregnant or breastfeeding
Allergy to latex
Heart & Vascular, Prevention, Sports Medicine
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Study Locations

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Location
State College, PA

GLNE 010: Validation and Comparison of Biomarkers for the Early Detection of Colorectal Adenocarcinoma

The purpose of this study is to see if stool, urine or blood can be used to find colon cancer as early or earlier than colonoscopy can. The researchers want to use these samples to learn about specific proteins or genes (also called biomarkers) that may indicate if someone has colon polyps (pre-cancer), colon cancer, or an increased risk for developing colon cancer. The researchers are part of a National Cancer Institute program called the Early Detection Research Network (EDRN). We have some biomarkers that are very promising, so we are testing them (“validating them”) in this study.
Amanda Taylor Gehman at ataylor6@pennstatehealth.psu.edu or 717-531-1283
All
18 year(s) or older
This study is also accepting healthy volunteers
NCT01511653
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Inclusion Criteria:
Scheduled for colonoscopy in the next 4 months
age 50 and older who are undergoing their first ever screening colonoscopy
adults age 70 and older with colonoscopy more than 9.5 years ago
willing to provide blood, urine and stool samples
able to tolerate removal of 5 tubes (3.5 tablespoons) of blood
Exclusion Criteria:
positive stool blood test (FIT/FOBT) in the past year
ever had colon or rectal cancer
history of inflammatory bowel disease
confirmed hereditary non-polyposis colorectal cancer, familial adenomatous polyposis, HIV or chronic viral hepatitis
cancer diagnosis or treatment in past year
Prevention, Digestive Systems & Liver Disease, Cancer
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Location
Hershey, PA

A Phase 2, Double-blind, Randomized, Placebo-controlled Multicenter Study to Evaluate Efficacy, Safety, and Tolerability of JBT-101 in Systemic Lupus Erythematosus

This study is for patients with Systemic Lupus Erythematosus (SLE) to test the effect, safety, and tolerability of the experimental drug JBT-101 in people with SLE to see if JBT-101 stops inflammation and how well JBT-101 is tolerated. The study will evaluate whether JBT-101 will decrease the pain associated with active arthritis or tendonitis in SLE patients.
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03093402
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Inclusion Criteria:
Be willing to not start or stop any NSAID or disease modifying treatments for SLE during the study
Be wiling to not use any legal or illegal cannabinoids, including FDA-approved cannabinoids during study participation
If female of child-bearing potential must be willing to use highly effective contraception during study participation
Exclusion Criteria:
Treatment with steroids in the past 28 days
Actively listed on organ transplant list or have received an organ transplant other than a corneal transplant
Have active or chronic infections
Have a history of cancer (except cervical treated successfully with curative therapy or basal cell carcinoma)
Have a history of significant heart disease
Arthritis & Rheumatic Diseases
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Study Locations

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Location
Hershey, PA

Imaging and Depression with or without MS

A study looking at the neural and genetic correlates of depression. Presently, the current study is looking to recruit individuals for two separate groups: 1. MS but NO history of depression 2. Depression but NO history of MS or neurological disease. The purpose of the study is to look at patterns of brain structure and function in individuals with depression and compare them to those with MS. We will explore how any differences we find contribute to more problems with depression in MS and see how such differences might lead to better treatment options for depression.
Cristina Roman at car342@psu.edu or 814-865-5578
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
Between the ages of 30-65
Able and willing to undergo an MRI
Able to travel to State College for the Study
Exclusion Criteria:
Current psychotherapy treatment for depression
Started anti-depressant medication in the last 2 months
Diagnosis of bipolar disorder, schizophrenia, or significant neurocognitive impairment
Very severe depression that would interfere with the ability to participate or suicidal ideations
Unable to undergo an MRI (metal in your body)
Mental & Behavioral Health
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Location
State College, PA

Gene-transfer, open-label, dose-escalation study of SPK-8011 [recombinant adeno-associated viral vector with B-domain deleted human factor VIII gene] in individuals with hemophilia A

Gene-transfer, open-label, dose-escalation study of SPK-8011 in individuals with hemophilia A. Primary Objective to evaluate the safety, tolerability and efficacy of SPK-8011 a recombinant adeno-associated viral vector with B-domain deleted human factor VIII gene.
Cynthia Campbell-Baird at cbaird@pennstatehealth.psu.edu or 717-531-5777
Male
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03003533
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Inclusion Criteria:
Hemophilia A
FVIII Level <1% or 1-2% with> 10 bleeds past 52 weeks or 1-2% on prophy treatment
Greater than 150 exposure days to Factor VIII concentrate or cryo
No evidence of Factor VIII Inhibitor
Acceptable lab values as defined by protocol
Exclusion Criteria:
Active Hep B or C &/or current antiviral therapy for Hep B or C
Significant underlying liver disease
HIV-1 or HIV-2 with CD4 count </=l to 200
Other investigational product in the past 12 weeks or gene therapy research within the past 52 weeks
Any other significant condition/disease that in the opinion of the investigator would make the subject unsuuitable
Blood Disorders
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Location
Hershey, PA

SPIRIT 1: An International Phase 3 Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study to Evaluate Relugolix Administered with and without Low-Dose Estradiol and Norethindrone Acetate in Women with Endometriosis-Associated Pain

Endometriosis is a common chronic condition that can cause pain in the lower part of the stomach (pelvis) during the menstrual period and at other times and pain during sexual intercourse. The purpose of this study is to test how effective and safe the investigational study drug, relugolix (rel-U-GO-lix), given with or without low-dose estradiol and norethindrone is in treating endometriosis-associated pain. Estradiol is a form of estrogen and norethindrone is form of progesterone. Both estrogen and progesterone are hormones normally made by women’s bodies. These hormones help control the menstrual cycle and menstrual periods and also support bone health. The study wants to know if endometriosis pain affects how women function, how they feel and if the study drug is effective and safe at treating the pain from endometriosis.
Heidi Watts at hwatts@pennstatehealth.psu.edu or 717-531-6272
Female
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03204318
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Inclusion Criteria:
Premenopausal female aged 18 to 50 years old
Has a diagnosis of endometriosis verified by surgery in the last 10 years
Has regular menstrual cycles (21 to 35 days long)
Has moderate, severe, or very severe pain during menstrual cycles
Is not expected to undergo gynecological surgery (or other surgical procedures for treatment of endometriosis) during the study
Exclusion Criteria:
Has a history of chronic pelvic pain that is not caused by endometriosis
Has had 4 or more prior laparoscopic, surgical, or other invasive procedure for endometriosis
Has had gynecological surgery or other surgical procedures for treatment of endometriosis within the 3 months prior to the Screening visit
Has unexplained vaginal bleeding outside of the patient’s regular menstrual period or pregnancy
Has a gastrointestinal disorder affecting absorption or gastrointestinal motility, history of or currently has osteoporosis or a systemic autoimmune disease
Pain Management, Women's Health
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Location
Hershey, PA

Neurophysiological Markers of Pediatric Irritability and its Response to Intervention

This study uses specific computer tasks to predict irritability in children with Attention Deficit/Hyperactivity Disorder (ADHD), as well as the effect of ADHD medication (stimulants) on irritability symptoms in children with ADHD. Children ages between the ages of 5 and 12 years are eligible and must have an established diagnosis of ADHD or suspected symptoms of ADHD.
All
Younger than 18 years old
This study is NOT accepting healthy volunteers
NCT03279952
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Inclusion Criteria:
Children between the ages of 5 and 12
Children diagnosed with ADHD or suspected ADHD Symptoms
Children who are able to stop ADHD medication for testing days
Parent/child fluent in English
Exclusion Criteria:
Children younger than 5 year or older than 12 years
Children with visual or hearing deficits or sensitivity to loud noise
Neurological conditions such as active seizure disorder
Prominent traits or diagnosis of Autism, marked developmental delay, mania, psychoses, or suicidal ideation.
Children's Health, Mental & Behavioral Health
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Location
Hershey, PA

Analyzing Student Newspaper Political Coverage

This study involves a content analysis of student newspaper political articles, as well as a survey of student journalists regarding their views about how politics are reported in student media.
Hans Schmidt at hcs10@psu.edu or 610-892-1251
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Journalism student
Involvement on student newspaper
Involvement with other student media
Exclusion Criteria:
No involvement in student journalism
Education
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Attention and Emotional Development in Children

Children with attention problems often feel anxious or worried, and likewise, children who are anxious or worried often have problems with attention. We are looking for children aged 8-12 who may or may not have problems with attention or anxiety to help us understand what happens in the brain that could explain why. You will receive up to $100 gift card for your participation, and informal clinical feedback on your child.
Caitlin Givens at ChildAttention@psu.edu or 814-863-0250
All
Younger than 18 years old
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Children aged 8-12
Exclusion Criteria:
Children outside of the 8-12 age range
History of seizures or photosensitive epilepsy
Children's Health, Mental & Behavioral Health
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Study Locations

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Location
Altoona, PA
State College, PA

Long-Term Nicotine Treatment of Mild Cognitive Impairment

The purpose of this study is to determine whether nicotine can improve symptoms of memory loss in people experiencing mild memory problems (referred to in this study as “mild cognitive impairment” or MCI). Recent studies have suggested that one of the causes of memory disorders may be a reduction in a particular chemical substance in the brain. This chemical substance, acetylcholine, is thought to act on certain brain cells in a specific way that helps us to remember and use memories as well as affect our attention. In people with MCI (and Alzheimer’s disease), the level of acetylcholine may be changed, and this may impair brain functioning. Preliminary studies have suggested that short-term administration of nicotine appears to improve memory in patients with mild memory loss and early Alzheimer’s disease (AD). It has been known for many years that nicotine imitates many of the actions of acetylcholine. By administering nicotine over a longer period of time to participants with MCI, we hope to better understand whether nicotine may act to improve memory loss symptoms over the longer term and whether it may help to delay the progression of memory loss symptoms. The amount of nicotine in each patch used in this study is the same as patches that are FDA approved for use in people who are trying to quit smoking.
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT02720445
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Inclusion Criteria:
Patient must have a subjective memory concern as reported by patient, study partner, or clinician
Age 55-90 (inclusive)
Study Partner is available who has frequent contact with the patient (e.g. an average of 10 hours per week or more), and can accompany the patient to most visits to answer questions about the patient
Must speak English fluently
Good general health with no additional diseases/disorders expected to interfere with the study
Exclusion Criteria:
Any use of tobacco or nicotine products within the past year
Any significant neurologic disease such as Alzheimer’s disease dementia, Parkinson’s disease, multi-infarct dementia, brain tumor, seizure disorder, etc.
History of alcohol or substance abuse or dependence within the past 2 years
Neurology, Mental & Behavioral Health
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Location
Hershey, PA

An investigation of the daily experiences of cancer survivors preparing for follow-up appointments: An ecological momentary assessment study

Have you been diagnosed with cancer? Have you completed cancer treatment(s)? Have you scheduled or are you planning to schedule a follow-up appointment? We are trying to understand how follow-up appointments impact the everyday health and wellbeing of cancer survivors. We are seeking men and women (age 30-75) who have completed treatments for cancer (stages 0-3), and have a scheduled or plan to schedule a follow-up cancer screening appointment in the next 30 days. In this study, you will be asked to: - Attend two remote sessions with a Penn State researcher via Zoom or phone call - Complete two online surveys - Carry around a study smartphone for 2 weeks to answer brief surveys throughout the day Participants in this study can receive up to $160 compensation for their time. If you are interested in learning more about this study or would like to find out if you are eligible, please contact our study team at (814) 424-5601 or email jaj53@psu.edu
Jillian Johnson at jaj53@psu.edu or 814-424-5601
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
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Inclusion Criteria:
Adult (aged 30-75)
Cancer diagnosis (stage 0 through 3 only)
Completed primary cancer treatment at least 3 months prior to participating
Have a scheduled or plan to schedule a follow-up cancer screening appointment in the next 30 days
Fluent in English
Exclusion Criteria:
No cancer diagnosis, or diagnosis of Stage 4 cancer
No access to desktop/laptop computer with active internet connection
Diagnosis of psychiatric disorder AND recent hospitalization
Visual impairments that would prevent use of mobile device or computer use
Severe cognitive impairment
Cancer
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Study Locations

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Location
State College, PA

A Phase 3 Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Two Dose Levels of BCX7353 as an Oral Treatment for the Prevention of Attacks in Subjects with Hereditary Angioedema

This study is for patients diagnosed with Type 1 or Type 2 Hereditary Angioedema (HAE) and have suffered HAE attacks (episodes of swelling), and are either not using HAE medications to prevent HAE attacks or for medical or personal choice reasons have decided to discontinue using these medications. This research is being done to compare the effects of two different doses of BCX7353 compared to placebo. Placebo-containing capsules look exactly like BCX7353 capsules, but do not contain BCX7353 or any other drug. The Sponsor will test two different doses of BCX7353 to see if BCX7353 is able to prevent or reduce the number of swelling episodes or attacks in people with HAE when taken every day by mouth, compared to placebo. This research study will also assess the safety of the new drug BCX7353.
Terri Smith at tjs97@psu.edu or 717-531-4513
All
All
This study is NOT accepting healthy volunteers
NCT03485911
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Inclusion Criteria:
Adults & Children 12 years or older
Diagnoses with HAE Type 1 or Type 2
2 or more HAE attacks per month
Exclusion Criteria:
Pregnant females or planning on becoming pregnant or nursing
Anticipated use of short-term prophylaxis for pre-planned procedure or surgery
Chest pain, heart attack, passing out or significant heart beat abnormality
Pacemaker or defibrillator implanted
Family history of sudden cardiac death not related to HAE
Infectious Diseases & Immune System, Allergies
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Location
Hershey, PA

Human Robot Trust in a Belay Experiment

Studying the factors affecting trust or lack there of when a human is belayed by a robot
Vidullan Surendran at vus133@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Over the age of 18
Have a basic proficiency of English
Physically able
Exclusion Criteria:
Under the age of 18
Physically unable to climb stairs
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Study Locations

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Location
State College, PA

Temperament, Evolving Emotions, Neuroscience Study (T.E.E.N.S.)

We are conducting a study examining factors associated with anxiety development in adolescence. We do this through questionnaires and observations of behavior in our laboratory. In this study, we will examine adolescent's emotional development through encountering novel social situations, measuring heart rate and brain activity, and using eye tracking during computer tasks.
All
Younger than 18 years old
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
>= age 13
read and speak English
Exclusion Criteria:
neurological disorders
developmental disorders
Autism
Mental & Behavioral Health
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Study Locations

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Location
Altoona, PA
Harrisburg, PA
Hershey, PA
State College, PA

Identification of Emotion in Music in Autism Spectrum Disorders

The purpose of the project is to learn more about reactions to music by adults with and without autism spectrum disorders. Participants will listen to short pieces of music and answer some questions on a computer. They will also complete some formal testing and answer some interview questions.
Diane Williams at dlw81@psu.edu or 814-865-3177
All
18 year(s) or older
This study is NOT accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Speak sentence length English as primary language
Normal or corrected to normal vision
Normal hearing
Individuals with and without an autism spectrum disorder or Asperger syndrome
Willing to consent and complete study requirements
Exclusion Criteria:
Cannot speak sentence length English
Vision problems (uncorrected)
Hearing problems
Significant learning problems
Unwilling to consent or complete study requirements
Mental & Behavioral Health, Language & Linguistics
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Study Locations

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Location
Greater Pittsburgh Area, PA
State College, PA

Investigating the emotional and behavioral response in humans playing games against a humanoid robot

We would like to study the emotional and behavioral response of a human playing games against a robot. Games such as Connect Four and card games will be used.
Vidullan Surendran at vus133@psu.edu
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
Show full eligibility criteria
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Inclusion Criteria:
Over the age of 18
Physically and mentally able
Basic proficiency of english
Exclusion Criteria:
Under the age of 18
Unwilling to have video footage of the experiment taken
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Location
State College, PA

Exploring Facilitators and Barriers to Self-Initiated Sexually Transmitted Infection Testing among College Student

The purpose of this study is to identify modifiable facilitators and barriers to self-initiated sexually transmitted infection (STI) testing among college students aged 18 – 24 years. This study will entail filling out a demographic and sexual history questionnaire, and a private face-to-face interview.
Oluwamuyiwa Adebayo at DAresearch@psu.edu or 814-867-4656
All
18 year(s) or older
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
aged 18 – 24
able to speak and understand English language fluently
able to provide written informed consent
engaged in sexual activity in the past 6 months
fit into either study Group I (self-initiated STI testing) or Group II (never tested for STI) or Group III (Clinician-initiated)
Exclusion Criteria:
Not meeting all the inclusion criteria
Infectious Diseases & Immune System, Men's Health, Women's Health
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Location
Altoona, PA
Harrisburg, PA
Hershey, PA
State College, PA
Williamsport, PA

Cardiovascular Effects of Angiotensin 1-7 in Obesity Hypertension

The purpose of this study is to see if the hormone angiotensin-(1-7) improves the function of blood vessels and lowers blood pressure in obese subjects with hypertension.
Aimee Cauffman at acauffman@pennstatehealth.psu.edu or 717-531-1617
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT03604289
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Inclusion Criteria:
Age 18-60 years
Obesity (defined as body mass index between 30-40 kg/m2)
Hypertension (defined as seated blood pressure greater than 130/80 mmHg)
Able and willing to give informed consent
Exclusion Criteria:
Pregnant or breastfeeding women
Current smokers
Type I or type II diabetes
History of major cardiovascular disease, immune or liver diseases, impaired renal or liver function
Age less than 18 years or greater than 60 years
Heart & Vascular
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Location
Hershey, PA

Examining Maternal Reward Responsiveness and the Intergenerational Risk for Depression

Children of depressed mothers are at high risk for developing depression, particularly as youth age into adolescence, yet relatively little is known about the mechanism underlying risk for depression in youth with depressed mothers. The present study examines maternal reward responsiveness, measured across neurophysiological, behavioral, and self-report measures as a marker of depression in mothers of adolescents. Associations between maternal reward responsiveness and parenting difficulties often associated with maternal depression, as well as adolescent functioning will be examined, to explore the clinical impact of maternal reward responsiveness on the intergenerational transmission of depression.
All
All
This study is also accepting healthy volunteers
N/A
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Inclusion Criteria:
Female adults 18 years and above with an adolescent child aged 13-16 years
Capacity for informed consent
Fluent in verbal and written English
Adolescent between the ages of 13 and 16 years (inclusive)
Exclusion Criteria:
Diagnosis of autism spectrum disorder, substance use disorders, schizophrenia or other psychotic disorder
Any hearing or visual impairments
Investigator discretion regarding ability to participate in the study
Children's Health, Mental & Behavioral Health, Women's Health
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Location
Hershey, PA

Postmenopausal women and their endothelium: Is acute dietary nitrate supplementation protective?

Cardiovascular disease is the leading cause of death in the United States. Due to the loss of estrogen, women experience a unique accelerated rise in cardiovascular disease risk factors following menopause. Postmenopausal women represent a population at heightened risk for cardiovascular disease development. The purpose of this study is to test the effects of a one time dose of beetroot juice on blood vessel function and resting blood pressure in healthy, postmenopausal women. Participants will drink beetroot juice and a placebo juice and blood pressure and blood vessel function will be measured.
Jocelyn Delgado at jmd956@psu.edu or 408-679-8390
Female
18 year(s) or older
This study is also accepting healthy volunteers
NCT03644472
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Inclusion Criteria:
Women following menopause
Exclusion Criteria:
Individuals taking hormone therapy
Individuals with resting blood pressure > or = 130/80 mmHg
Users of any tobacco and/or nicotine products (smokers, chewing tobacco, nicotine-containing patches/gum, smokeless cigarettes)
Individuals with any overt cardiovascular, metabolic, hematologic, pulmonary, renal, musculoskeletal, and/or neurological disease(s)
Food & Nutrition, Heart & Vascular, Women's Health
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State College, PA

Site For CLOVERS

Site For CLOVERS
Nancy Campbell RN at ncampbell1@pennstatehealth.psu.edu or 717-531-1707, ext=3
All
18 year(s) or older
This study is NOT accepting healthy volunteers
NCT00343402
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Inclusion Criteria:
Age > 18 years
Suspected or confirmed infection
Sepsis induced hypotension
Exclusion Criteria:
> 4 hours from start of hypotension
> 3 L intravenous fluids
Pregnancy
Severe volume depletion
Immediate surgical intervention planned
Infectious Diseases & Immune System, Heart & Vascular
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Study Locations

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Location
Hershey, PA